Top similar games like Defense Grid 2:

Defense Grid: The Awakening is a unique spin on tower defense gameplay that will appeal to players of all skill levels. A horde of enemies is invading, and it's up to the player to stop them by strategically building fortification towers around their base.

Sanctum 2 is the sequel to the world’s first Tower Defense/FPS hybrid game. Pick from four unique character classes and embark on a mission to protect the oxygen-producing Cores from hordes of deadly aliens who are threatened by their existence.

"You are outgunned. You are massively outnumbered. You must win." These are your orders. Humanity has already fought its war against the machines -- and lost. AI death squads stand watch over every planet and every wormhole, the few remaining human settlements are held captive in orbiting bubbles, and the AIs have turned their...

Co-op and Single player Tower Defense genre.

ZAMB! Endless Extermination is a mash-up of a twin stick shooter and a tower defence game. Play in local co-op or online with a friend, sibling or partner as two space agents, Cye (the brawler) and Chrome (the tactician).

You think Tower Defense games are all about building? You thought wrong. Sanctum is not your average Tower Defense title. When the havoc starts, you get to join the fray! As one of the world’s first First Person Shooter - Tower Defense games, Sanctum has taken the best of both worlds to deliver an epic, one-of-a-kind experience.

Jump in to intense turret defense action with Sol Survivor! Build turrets to defend your colony and the innocent colonists within. Smash enemies with volleys of actively-controlled orbital support. Play with friends in co-operative and competitive multiplayer matches or test your mettle against our new Survival mode!

Creeper World 3 is what happens when cellular automata takes over a strategy simulation. Instead of discrete units that attack your base, a fluid-like substance spreads over the terraformable terrain. Your base, your weapons, your strategy... you must adapt them all.

Sci-fi Tower Defense real-time strategy with pleasant adaptive music. Play as a commander of a space station which got stuck in a time anomaly.

Anomaly 2 is a sequel to the critically acclaimed Anomaly Warzone Earth. Maintaining the core elements of the original, Anomaly 2 adds plenty of new features: unit morphing, over million tactical combinations, post-apo world and tower defense vs tower offense multiplayer mode.

Bring your toys to life in this action-packed, Toy Soldiers game bundle which includes the original Toy Soldiers, Toy Soldiers: Cold War, and all four DLC’s – Kaiser’s Battle, Invasion, Napalm and Evil Empire.

Spaceships, lasers, and… chickens! What more could you ask for?Conflicks: Revolutionary Space Battles is a creative new take on space-themed videogames that merges the deep, thoughtful gameplay of strategy games with the intuitive accessibility of physics-based games.

Build up your fortifications, place your cannons, and fire at the enemy forces! Improve your Battle Haven with powerful upgrades while playing through a story campaign comprised of dozens of scenarios with unique mission types and multiple boss fights! Take to the sky and win!

Colony Siege combines the best of RTS and tower defense, including base building, mazing, and unit physics. Defend Earth's remaining colonies using an arsenal of deadly weapons to torch, slice, throw, and impale swarms of alien invaders.

Galcon 2 is a demolition derby in space! Send swarms of ships from planet to planet to conquer the galaxy in this fast paced multiplayer strategy game!

Tikiman the Forest Defender is in trouble. Hordes of monsters are sweeping through his realm, hoping to chow down on his offspring – and it’s up to you to defend them. By placing weapon towers at strategic points around the landscape, you can destroy the invaders and save the little ones.

The ultimate mash-up of Real-time Strategy and Tower Defense!

Strategy co-op online multiplayer game about living on a spaceship with your roommates. You'll need to generate resources, take care of a deadly alien infestation, upgrade your appliances and build your sustainable space home. Living together is never easy, especially when you are in outer space!

Polarity takes it to the next level, demanding all of your wits and reflexes. Full-featured local co-op campaign.

Slice them, burn them, skewer them, and launch them - no matter how you get it done, orcs must die in this fantasy action-strategy game from Robot Entertainment. As a powerful War Mage with dozens of deadly weapons, spells, and traps at your fingertips, defend twenty-four fortresses from a rampaging mob of beastly enemies, including...

Warstone is a Tower Defense game, with RPG, Strategy, and even city building elements. Detailed Hi-res graphics and beautiful illustrations combine with a deep storyline to draw you into the world.

Dungeon Defenders Eternity is the definitive version of the original tower defense action-RPG! Now featuring a rebalanced endgame, all new missions, secure online play, links to Dungeon Defenders II and more!

A modern take on the 16-bit era, A Valley Without Wind 2 blends a variety of mechanics across multiple genres, seamlessly bringing together the best qualities of old-school platform-shooters and turn-based strategy games.

Online Co-Operative Tower Defense with endless build options and a heavy focus on rewarding creative strategies. With so many Levels, Towers, Abilities, Items, & Builder Specialties every match can be a different experience!

Taur is an action-strategy sci-fi game. Control the Prime Cannon and unlock all of its powerful weapons and abilities. Build turrets, droids, aircraft and more as you fight to protect the homeworld of the Tauron droids against a relentless invasion. Will your Taur stand against the Imperion warmachine?

Do you like Tower Defense games with Strategy elements? Well, look no further! We've got exactly what you're looking for! Get ready to defend your settlement from enemies using a huge arsenal of towers!

Play as humans or robots in a brand new sci-fi strategy adventure! Travel into the far reaches of space, through cleverly designed star constellations and variable game modes, conquering enemy planets using 15 combinable technologies.

Exo TD is a true 3D space Tower Defense. Invaders have scouted your planet as their next target, you must protect it by building destructive turrets, orbital defenses, shields, drones and more to defend against the incoming invasion force.

2D Tower Defense game set in a colorful world of Crayons. Over 20 different Maps with plenty of fun Weapons at your ready to defend the Crayon Empire. Can you survive the onslaught?

Fight off hordes of monstrous mutants created from a strange cataclysmic event in the new tower defense game, Prime World: Defenders. Join a group of exile treasure hunters who have ventured into the capital of an ancient empire, vast with mystery and danger.

Castle Story is a creative voxel-based strategy game in which you can build castles one brick at a time using an army of little creatures called Bricktrons. Design and build your own castles, expand your territory in a vast landscape and defend your Bricktrons against onslaughts of hostile creatures.

Lead an armored squad through the perils of this reversed tower defense action-strategy game!

Defenders: Survival and Tower Defense is a Cooperative First Person Shooter that redefines the tower defense genre. Team up with friends, drop in to a variety of diverse maps, and defend The Core from waves of hostiles with a unique arsenal of upgradable weapons and towers!

Zero Gravity is a beautiful first-person/third-person puzzle-platformer simulation game where you will undergo four types of game modes. (Zero Gravity is being recreated, find more info in the 'Early Access Description')

Galaxy in Turmoil's conceptual Early Access game is a FREE multiplayer combined-arms game set in a brand-new universe, created by a team of volunteers. It’s all about endless arms races, corporate espionage, and, most of all, blasting up on the enemy faction and taking their stuff.