Top similar games like BioGun: Clinical Trial:

Get injected into the microscopic world of BioGun. Face viral threats and winding corridors on your mission to save man’s best friend from the inside. Will you be the vaccine to save dog-kind from extinction or will DocX have to return to the drawing board?

A cute Hand-Drawn platformer adventure about a brave doggy in a mysterious dreamland where the sun and the moon have stopped moving!

Marko: Beyond Brave is an action-packed Metroidvania adventure. Wander through lush forests and crumbling castles, battle corrupted creatures, and escape intricate traps. Jump, slash, and shoot your way through challenging foes and mighty bosses inspired by Slavic myths and legends.

Unite the FELLAS and fight for FREEDOM!

Drilly Willis has a drill for a head and mad guitar skills. Save music for eternity by fighting your enemies with a one-of-a-kind drillhead weapon, jam songs on your guitar to grant special powers and abilities, and explore an interconnected world of bizarre creatures!

The Way Home is a Metroidvania 2D platformer where you play as a raccoon, separated from his family, who must flee from a raging forest fire. Explore the vast and beautiful woodland, find hidden secrets and collect useful items, and avoid dangerous enemies and obstacles.

Revive Orpheus story to save Eurydice

Fly into a charming handcrafted world and go on an adventure that mixes up open exploration with crispy twin-stick shooter action. Fight your way from the shiny overworld to the deepest caves, improve your ship and overcome the dungeons' bosses to rescue your friends!

Flow gracefully through a colorful, hand-drawn 2.5D action platformer inspired by Japanese folklore. Engage in acrobatic aerial combat, unlock powerful mystical abilities, and explore an interconnected world of myth as you seek to unravel the mysteries of your origin.

Explore a strange planet, collect the creatures you find, and then shape-shift into them to expand your world. Build your own path, chat with the locals, and discover the planets sprawling secrets in this quirky metroidvania platformer.

"Absence of Light" is an exploration based shoot 'em up that combines intense bullet-dodging combat with a metroidvania-style level design. Solve, shoot, and shine your way through the kingdom of Luminara and reawaken the light!

Lead Rolly in his adventure within the wonderful world of Shroomast, and explore its deep semi open-world underground. Goo Keeper is a pure metroidvania with tons of unique bosses, hand-crafted worlds and creatures, and tons of awesome abilities.

Unravel the secrets of the past to save the future! Battle corrupt gods, hunt dangerous beasts, and explore a vast, varied open-world teeming with new friends and new threats. In this epic fantasy, bring balance to a crumbling world, all in classic, hand-drawn 2D animation.

Restore the Sun’s light and end the Eternal Eclipse in this 2D fast-paced action-platformer game inspired by Peruvian cultures. Explore hand-crafted environments, battle and improve your skills to defeat the Four Keepers that stole the power of the Sun.

Save Moses' girlfriend from the clutches of the prince of Egypt, Ramses, in this thrilling adventure across the Egyptian desert. Face enemies and bosses, find items and power-ups scattered throughout a fantastic 2D open world full of challenges, secrets and much more!

Welcome to TRAXION²! Again you take the role of a daring starship pilot, embarking on a series of break-neck missions into the caves of a dangerous alien planet. This time around, you can join forces with a second player, or challenge each other in deadly deathmatch mode!

A stray dog survives in a cruel world of humans and animals. There are two ways: to become a wolf or to give humanity a chance. Paper Bum is a dark adventure that looks like the drawings of a sad child.

Follow a young Kewtian called Starter as he barrels through tons of boss fights, explores colorful environments, and meets strange characters in this action-packed Metroidvania adventure!

Evil forces have invaded Goobstar! Join Goobert and his friends on their quest to save the denizens of planet Goobstar from the invading balloon menace in this wacky hand-drawn shoot em' up, and watch the world grow around you!

Without kidney is a shooter metroidvania game with a hero who can hook like spiderman and jump with cannon explosions. Using a grappling hook, a cannon and other bonuses, that can be found on the way, you go forward to the main Capitalist BOSS

Hand-drawn bullet-hell! A frenetic shooter combining the run-and-gun mechanics of Metal Slug with the infinite loops and shmup-ing of Resogun, wrapped up with old-fashioned drawn-on-film style animation. Fight your own creator as the artist bears down on you with pen and paintbrush!

Chaotic Pursuit is a hardcore Top-Down Shooter with cute graphics. You miss a shot and you're out!

Explore the mysterious island of Kindara in this vibrant 2D action-adventure. Fight and platform your way through jungles, icy peaks, castles, and crystal caverns in a non-linear interconnected world. Adventure awaits!

Explore an interconnected world, encounter bizarre enemies and mysterious puzzles in this hand-drawn metroidvania, action adventure. Forge your own path, uncover secrets and master unique powers.

What's the Matter? is a fun and challenging twin stick shooter that introduces the player to the periodic table of elements. Features hand drawn graphics, original jazz tunes and randomly generated levels.

Fantasy Network is a metroidvania game with a social media twist! Explore the colorful world of Holua and chat to hand-drawn, larger-than-life characters to discover a story that runs deeper than it may seem. Help Lyn to safe her mother and win the President's race!

An exciting and fun platform game. play with a fancy computer head full of dangling wires. I know, it may sound weird, but hey, you're in Freakland bro!

"Charlie from the swamp" is a metroidvania game about little frog in a big world.

Guide this pink being with the power of the ether in a metroidvania where nothing is as it seems. Infuse souls into objects, create minions to help you, and explore vibrant landscapes with a great soundtrack. Shape your destiny on this captivating journey.

Join young Mako as she ventures into a wild world of exploration and finds a mysterious bird companion. Navigate through two distinct realms with your staff and face off against an ancient sentinel in this prologue to the action-packed metroidvania Akatori.

Enter the prehistoric world dominated by primal reptiles. Fight through savage enemies and bosses with the combination of melee & ranged combat and elemental magic. Explore the vast handpainted world and try to prevent the meteor from wiping out all life on the planet.

Trash Quest is a compact metroidvania with a single spawn point, run and gun action and tight platforming. Navigate an interwoven maze of rooms through this space station, destroying robots, collecting power ups and unlocking shortcuts.

Akita: King Pig Thinks Pink is a 2D adventure-platformer metroidvania with hand-drawn animations, for 1-2 player local co-op.

Bazooka Cat is a platformer made with love inspired by old-school games of the 90s with the use of new technologies and game logic, but what if you add something like tactics to the platformer?