Top similar games like Genome Survivors:

Reject boring stat stacking! We've restructured the gameplay with limited talent resources—talent combinations are just as important as character selection! With 200+ items and 40+ pieces of equipment, what insane builds can you create? —Depth! Difficulty! And high replay value!

Hold the line against hundreds of monsters in a bright, top-down survival roguelite. Pick one of four heroes, time your abilities, and grow a build that turns a desperate fight into a screen-clearing storm. Four realms, a boss at the end of every round, and always one more run.

Become the hero in this fast-paced incremental roguelike game! Show off your reaction skills to your Overlord, earn massive gold, stack game-breaking upgrades, and forge powerful combos to survive relentless enemy waves.

A free-form arena-shooter Roguelite with heavy emphasis on building an overpowered character! You play as a little shape that shoots other shapes! Strengthen your character by mixing and matching mods and upgrades, and experiment with a limitless rune upgrade system!

Franco and Apollo is a rogue-lite survival action game with auto-shooting. Fight against hoards of enemies side by side with your robot dog. Combine weapons and characters to get stronger and be able to defeat all the bosses!

Choose your race and class, create a unique build, and battle relentless hordes in VERAKORIA. Collect experience, unlock powerful upgrades, defeat deadly bosses, and survive the escalating onslaught in this pixel-art action roguelite.

Shlack! is a top-down roguelite where you play as an artist trapped inside their own magazine. Survive against your own characters and drawings.

ZANOKA is a single-player roguelike action hack and slash and survivorlike where every sword swing is yours. Chain light and heavy cuts into combos, time your dodges and combine elemental upgrades against enemy waves and bosses. Every run is different, and every run can reveal a new build.

Survive relentless enemy waves by broadcasting on risky frequencies. Upgrade, adapt, and defend your radio station in this post-apocalyptic top-down survival game.

Don’t just mow down the horde—weaponize the battlefield. Lure enemies into spinning gears, ignite fuel slicks, chain lightning through metal, fuse bubbles with abandoned mechs, or hurl cars into the swarm. 9 hunters bend the arena in different ways, and every run lasts 10–15 minutes.

Survive procedural fantasy biomes in a 3D top-down bullet-heaven action roguelite with survivors-like build growth. Upgrade auto-fire weapons, earn and upgrade active abilities, unlock powerful ultimates, defeat bosses, and push into Endless Mode.

Gnomekeeper is a cozy-weird bullet-heaven roguelite. You’re one garden gnome, the sun has quit, and everything in the garden wants you gone. Fend off the swarm, cobble together a ridiculous build, and see if you make it to morning.

A casual top-down game with simplified roguelike elements, where a ginger cat named Meow battles endless waves of enemies. Gain experience, upgrade your skills, find the most effective combination of abilities, and try to survive as long as possible.

Shoot, slash and slay the enemy hordes erupting from the jungle’s Membrane in this action survival roguelite. Hold the encircling trenches, fortify them, choose your build and rise from loinclothed-servant to unstoppable Amazon king.

Shoot your way through endless waves of government drones! Grab loot, level up, unlock pigeons and upgrade to create unique and crazy builds as you fend off mindless government of creatures.

A fast roguelite survival chaos where you destroy endless plague hordes, stack insane upgrades, and break the rules of power.

You play as a speedy raccoon on his quest for snacks. Collect fruits that make you strong and break those sweet trash cans open! Unlock fancy skins and powerful upgrades while enjoying hand-crafted art and music.

This is an action RPG with Rogue-lite and loot-grind. Level up, learn skills, gem your gear, and grab loot to power up. Create your own build. Then go deeper into the spiral void and take on tougher darkness.

Crystalysis is a fast-paced slingshot game with survivors-like builds and roguelite elements. Defend your crystal from waves of enemies. Every level you pick up upgrades. Stack them into a build, mix passives and weapons and evolve them to achieve your crystal aspects.

Sigma Survivor is a roguelike type game. Lead your hero and survive the whole round while enemies of every kind cross your path. Grab power-ups, take risks, play MINIGAMES, upgrade your character, and come back stronger with every run!

Sidequest Survivors is a bullet-heaven roguelite where you control wacky characters, mow down waves of magical creatures, and tackle sidequests. Choose from a variety of weapons and create builds that match your playstyle.

Slay Goblins is an arena roguelite where you play a knight fighting off hordes of goblins. Choose from a variety of perks, weapons and items to create unique builds and defend your castle.

Your harvest has a health bar. Defend it as a gun-toting pumpkin in this colorful action roguelite. Dodge monster waves, upgrade your weapons and turn defeated foes into fertilizer. Survive the night, save your crops and unlock your next guardian.

Assemble your own combat machine from interchangeable components and weapons to mow down hordes of enemies in the arena of this dark cyberpunk survival roguelite. Every part changes your build — combine them to create devastating synergies to survive increasingly brutal waves.

Become a one-outlaw army in a haunted western bullet heaven. Dodge the restless dead, evolve your weapons, and tackle optional objectives across four frontiers. Survive until dawn, saddle up, and ride home with your bounty.

Bullet Heaven x Endless Loot! Create Your Own Build in this Roguelite Action RPG.

Geometry Arena 2 distills RPG depth and Roguelite elements into a unique loop of [ Meta-Progression + Endless Challenges ]. Mix and match Weapons, Bodies, Modules, and Pets to craft your game-breaking builds! Minimalist lines, vibrant colors!