Top similar games like Iosis:

Survive waves of merciless enemies as an engineer defending generators. Use agility, firearms, and strategic towers. Choose from explosive or piercing weapons. Upgrade, adapt, and conquer in dynamic landscapes. Stunning graphics, intense gameplay – your courage is key to victory.

In this Tower Defense Survivor Game, the skill tree is on the ground of the battle map. Expand your base to capture more of the map and unlock more upgrades. Defend your position against thousands of enemies as they flow over the map.

Discover the beauty and fragility of life in Survivor Cells, a unique survival game against viruses and bacteria, which strategically combines the elements of roguelite, bullet hell and tower defense in a challenging experience. Your destiny depends on your agility and choices. How far will you get?

In Brave Bubble Heart you'll face strange creatures and solve puzzles while saving as many souls as you can that are lost in the abyss. Do not die!

Tower Tactics Arena is an action roguelite set in the Tower Tactics: Liberation universe in which you'll fight intense waves of enemies in a closed combat arena! Level up your towers strategically and collect powerful trinkets and potions! Will you claim victory in the arena?

Battle time and terror in a shoot & survive extraction roguelite. Select your hero and survive the relentless cosmic surge. Shoot, level up, topple bosses, and amplify your powers to cosmic levels. Embrace the Blastard within and unlock new heroes, powers, and perks to use on future runs.

Arcadium is a roguelite shooter set in a dynamically generated universe. Journey across space, harvest planetary resources, and craft powerful builds to eradicate relentless waves of aliens. Each playthrough unveils a new and uncharted universe, ensuring endless challenges and discoveries.

Tower Defense mixed with Roguelike! Build overpowered Towers to beat masses of enemies. Unlock up to 5 different characters, more than 25 Towers and conquer epic boss battles to prove your strategic prowess in this endless battle for survival!

Deep Nest is a fast-paced single player action shooter roguelite where you play a space marine fighting off an endless horde of alien monsters in an infested facility.

Fantasy Madness: Bloodbath is a roguelike action-survival game where forces of nature fight against hordes of evil. Gain new skills, loot powerful items and defeat all who stand in your way… By all means!

Master aerial acrobatics and bend time to your will in this roguelite, where strategic depth meets intense acrobatic gameplay. Travel through time to unlock powerful synergies with upgrades that turn you into a godlike sky matador. Gear up, pilot—it's time to rule the skies.

A sci-fi roguelike about a lone pilot on a forbidden mission through his galaxy. Piece together his story as you scavenge to build your loadout in this procedurally generated space shoot'em-up.

Dangerous Galaxy is a rogue-lite adventure focused on the freedom to create your ultimate spaceship while managing resources, completing missions, and defeating various enemies and boss battles.

Craft a starship from hundreds of unique weapons, battle through waves of enemies to rescue stranded survivors and gather resources - Use them to rebuild your homebase and unlock powerful upgrades. Restore the lost civilization and strive for a new future for the people of Verdantia.

Step into an exciting journey in Cats Guns & Robots, a rogue-like action game where you are the last hope for the world. In this outlaw-like action game, surviving enemy attacks in each room will require careful choices of upgrading your character abilities and features of weapons in your inventory.

Prepare for an interstellar showdown like no other in a gripping roguelike top-down twin-stick shooter set in the vast depths of space. Pilot your advanced starship, engaging in relentless battles against hordes of alien adversaries. Destroy, Collect, Upgrade, Die, Unlock, Repeat.

Beat up planets in Asterogues, a cosmic bullet hell shoot-em-up hybrid! Pick your character from a band of outcasts banished to the Asteroid Belt, dodge and shoot your way through a brutal onslaught of bullets, and take revenge against the Solar System!

Hopeless Sea is a roguelike, arcade-inspired, top-down shooter. You pilot a ship to cut your way through hordes of procedurally generated, merciless sea monsters. Choose wisely from a variety of ships, weapons and upgrades since conquering this hopeless sea is the only way to survive.

Unleash the fury of giant capital ship combat and conquer the stars!

It’s time to cluck around and find out. Gear up and pull on the helmets of the Battle Roosters, a hotshot space brigade of poultry with panache. In this quirky, roguelike, bullet hell adventure you’ll combine weapons, upgrades and killer strategies to recover space’s best taco ingredients. Bwark!

You are a gunslinger in limbo, involved in a gritty war against "The Cartel", a ruthless organization harvesting souls to break free of the shackles of the afterlife. Grow stronger with each new run, gather the essence of lost souls to take on the biggest threats in this rogue-lite FPS!

Collect weapons and destroy enemy ships

Roguelike bullet hell shooter, where you fend off waves of attacking monsters in a constantly transforming arena. You are rewarded with upgrades to your vulnerable spaceship if you survive long enough.

Prepare for an interstellar showdown like no other in a gripping roguelike top-down twin-stick shooter set in the vast depths of space. Pilot your advanced starship, engaging in relentless battles against hordes of alien adversaries. Destroy, Collect, Upgrade, Die, Unlock, Repeat.

Sleep Stream is a roguelite survivor game that exquisitely combines the fun factors of roguelite with the tension of survival. Host a bloody livestreaming to fall asleep with synergy combinations and equipment enhancements to match Layla's various personas.

Build a stronger ship with each play session as you earn resources needed to upgrade your ship and apply stronger weapons. Customize your ship to your play style and tackle greater and stronger enemies as the levels continue in this endless roguelite.

Nova Drift distills the mechanical depth and strategy of an ARPG into classic arcade space combat. Control an endlessly evolving bio-mechanical ship, face legions of strange and deadly foes, and ride the wake of a dying star across the void.

Blast your way through robotic hordes in this auto-battler arena shooter. Use auto-firing weapons and drones, timely dashes and special abilities to reach the Void where a final Conservator Custodian awaits computational convergence. Spend your Cogs wisely among the shops to create unique builds!

Stranded in a distant galaxy, portal jump your way home and defeat the DraadMek in this roguelite space shooter adventure. Unlock epic upgrades, explore alien galaxies, make friends, find love and do battle against a relentless alien AI threat.

Time-Stop Horde Survival Roguelike — from the creators of Backpack Hero! Build your deck. Stop the flow of time: think strategically, set up devastating combos, weave impossible odds in your favor.