Top similar games like Iosis:

Spectral Realm is a top-down tower defense Rogue game, where players need to play the role of an astronaut who has just landed on a different planet to block a constant stream of attacking native creatures and continuously strengthen themselves with the gems contained within their bodies.

Stranded in Starlight is a top-down roguelite where you pilot a spaceship armed with a variety of unique weapons and utilities. Battle relentless enemy hordes and powerful bosses as you upgrade your ship, adapting to each challenge in an ever-changing fight for survival.

Fight for survival in B.L.A.C.K - 1, a 3D FPS roguelike set in a dystopian future. Battle through procedurally generated spaceships using all your skills and resources, in Zero-G environments. Can you survive long enough to finally escape from enemy territory?

This roguelike spaceshooter pits waves of enemies against you in your pursuit to reach the end of the galaxy. Improve your ship with permanent upgrades and select temporary upgrades during a run to pursue achievements and and kill bosses.

Kuiper belt survivor is an arcade style bullet heaven, where every run is endless. It brings a unique spin to the bullet heaven genre by making every part of the players weapon arsenal customizable with well over 10,000 unique weapons to build, and unique stats for every enemy.

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Discover the beauty and fragility of life in Survivor Cells, a unique survival game against viruses and bacteria, which strategically combines the elements of roguelite, bullet hell and tower defense in a challenging experience. Your destiny depends on your agility and choices. How far will you get?

Starship Architect is a high-octane roguelike where every decision counts. Battle relentless enemies, choose from a dynamic arsenal of weapons and upgrades, and strategically assemble your ship. Unlock powerful new parts after each run and craft the perfect starship.

Decimate endless hordes of enemies across the nine realms of Yggdrasil for eternal glory! Plains of Havoc is a fierce 2D top-down roguelite set in the Viking afterlife in which you fight for your rightful place on the global leaderboards.

Orbit Express is a physics-based roguelike game. Pilot your delivery spacecraft through a procedurally generated galaxy, creating a unique challenge every time you play. Avoid collisions, upgrade your craft, mind your fuel, and master your flying skills, all for a minimum wage!

Survive relentless swarms of shadow creatures by building, upgrading, and unleashing towers in a roguelike arena defense.

Command your ship in Conqueror Of The Galaxy, an intense roguelite survival and bullet hell game. Face relentless defenses as you conquer entire galaxies, overcoming swarms of enemies and choosing strategic upgrades to become the ultimate conqueror!

Deploy your turrets and defend against an ever-growing mechanical horde! Upgrade your turrets separately in unique ways, use unique character abilities, and create powerful synergies.

Seedovia is a rogue-like dungeon crawler where you traverse room after room, fighting challenging monsters. Chain your weapons, collect game-changing passive upgrades, and equip items to create unique builds and become increasingly more powerful.

S.R.A Project is a challenging roguelike bullet hell wave survival game. Face cosmic creatures, improve through skill and perseverance, and master a world that rewards learning and adaptation.

Sleep Stream is a roguelite survivor game that exquisitely combines the fun factors of roguelite with the tension of survival. Host a bloody livestreaming to fall asleep with synergy combinations and equipment enhancements to match Layla's various personas.

Tri-Star is an endless horizontal-scrolling space shooter featuring Roguelike and Roguelite elements. Blast through waves of enemies and battle against arduous bosses. Form a squadron of three unique ships from an expanding roster and equip them with upgrades as you engage in a battle for survival.

In Brave Bubble Heart you'll face strange creatures and solve puzzles while saving as many souls as you can that are lost in the abyss. Do not die!

A shooter in the space arena, in which you grow from a small, clumsy to a powerful capital spaceship, using resources obtained from destroyed hordes of enemies and other cosmic evil.

Arcadium is a survival roguelite set in a dynamic, ever-changing universe. Journey across space, harvest planetary resources, and craft powerful builds to eradicate relentless waves of aliens. Each playthrough unveils a new and uncharted universe, ensuring endless challenges and discoveries.

Prepare for a radical shift in Bullet Hell gameplay! In Cursor Survival, you're not piloting a character - you embody the... CURSOR! Unleash a new, utterly insane way to evade, strike, and endure in a chaotic universe of projectiles and adversaries.

To the monsters, you don’t even exist. Their eyes are fixed only on the Princess. Protect her no matter what! Even when you feel like running away from her yourself.

Bend time to your will in The Chronos Event, a fast-paced third-person roguelite shooter. Rewind the clock, team up with your past selves, and battle hordes of enemies. Master time-looping, gain game-changing upgrades, and face down a hostile future in this time-bending sci-fi adventure.

In this Tower Defense Survivor Game, the skill tree is on the ground of the battle map. Expand your base to capture more of the map and unlock more upgrades. Defend your position against thousands of enemies as they flow over the map.

Against Great Darkness Prologue is a brick-breaking, roguelite where you play as a pagan trying to escape Hell's maw. Trigger relics by keeping your disks bouncing, experience unique events where you can obtain incredible loot, and battle hellish bosses while always keeping an eye on your disks.

Dungeons & Guns is a pixel art visual, dungeon crawler style game, where the player aims to advance as far as possible through the enemy crowded dungeons, until reaching the final challenge. After this, new challenges will arise.

A fast paced, action packed, roguelite game with tanks! Blast your way through procedurally generated levels, and build overpowered combinations of upgrades! Face off against a variety of different enemies and epic bosses.

As The House of God races towards heaven, Jack blasts their way to the conductor in this chaotic and fast-paced Rogue-Lite.

Tower Tactics Arena is a fast-paced action roguelite set in the Tower Tactics: Liberation universe. Battle relentless enemy waves in a closed combat arena, level up your towers strategically, and gather powerful trinkets and potions! Will you claim victory in the arena?

Play as a Bonfire Spirit, unleashing flaming bullets to fend off relentless waves of shadowy foes. Master dynamic movement, evolve your powers, and adapt to the ever-shifting chaos. Keep your flame burning in this fast-paced, stylized 2D action-roguelike, where every moment is a fight for survival!