Top similar games like Defenders of the Omniverse:

Sleep Stream is a roguelite survivor game that exquisitely combines the fun factors of roguelite with the tension of survival. Host a bloody livestreaming to fall asleep with synergy combinations and equipment enhancements to match Layla's various personas.

Survive thousands of monsters in X-Mutation, a hardcore 3D top-down rogue-lite action game. Mutate your body into diverse weapons, choose from hundreds of mutations, and uniquely upgrade to craft your personal combat style!

Robot Arena Survivors is a single-player arena auto-shooter where you're fighting against waves of hostile robots using a powerful arsenal made of hover tank units. Customize your own set of abilities and dismantle your enemies to claim your fame into the leaderboards.

Gacha Fever is a suvivors like in a cute and colorful universe. You will fight waves of monsters with various weapons, from the machine gun to the magical girl wand and the Bubble Tea Canon ! Just be careful of the area !

This game involves continuously defeating generated enemies to survive. When you defeat enemies, you have a chance to obtain gems, coins, or boxes. Accumulating gems allows you to level up, and upon leveling up, you can randomly acquire weapons or skills.

Face the Lords of the Void and their endless minions, collect their Soulstones and become a god! In this Action Roguelite, unveil secret spells, craft mighty weapons, unlock multiple characters, discover game-breaking synergies and conquer the power of the void.

A fast-paced action roguelike where you play as a tiny and adorable poop fighting off bacteria. Upgrade your weapons and items to escape the toilet and claim victory!

Terminal Breach is an action rogue-lite twin stick shooter where you gun down countless waves of creatures, choose upgrades to create powerful and unique synergies and unlock a variety of characters, weapons and levels.

Embark on an online co-op Survival Roguelite adventure. Team up with friends, slash through endless waves of foes, conquer formidable bosses, fulfill quests, craft potent weapons, and unlock unique characters!

Bring It On! is a single-player auto-attacking 'monster'-hell shoot-em-up survival game. Take on MASSIVE hordes of monsters across several locations, earning experience points to level up and acquire new weapons and items, and unlocking lots of unique characters!

Pass your magic exam with flying colors by surviving a final test within our dungeons. No worries, even though there may be numerous, highly resilient, and quite deadly exam golems, there is still time for you to excel, enhance your abilities, and learn a few new spells along the way.

Fight your way through the hordes of Baalzebub with your ghostly followers. Loot items for your followers to use, and sacrifice them to increase your power for the next assault.

Gear up for an epic battle through hell in this next-gen autoshooter with Doom-inspired gore vibes, roguelite mechanics, and a deep, satisfying combat feel. Wield five weapons at once, upgrade and merge them to forge indestructible builds, and bring divine justice to a world on the brink of chaos.

Embrace darkness, bargain with the dark gods and make unique pacts for incredible powers and skills. Combat humanity's armies and bring about the apocalypse in this dark fantasy bullet heaven action RPG. Become the ultimate Fallen Slayer and leave no Survivors.

You thought you landed alone. You were wrong. Now you must defend yourself against waves of enemies in order to survive. Vanquish thousands of foes, master your abilities, call in reinforcements, and survive in a quest to become a true Defender.

Shape Shifter: Formations is an action twin-stick shooter with rogue-lite elements, where you must destroy hordes of geometric enemies alone or with a friend. Select your ship and combine a large variety of weapons, abilities and infinitely stacking upgrades to craft your own unique build.

Survivors of Mayhem - a fast paced fantasy survivor game. Embark on a heart-pounding journey through waves of fantasy battle, where chaos reigns, and your every decision could mean the difference between life and death.

School Fighter is a top-down arena roguelite shooter where you play as a student who fights off school enemies using paper airplanes. You have access to a school shop, unique perks, and an upgrade station to help you create a powerful character and overcome the school nightmare!

Invent your own weapons in this sci-fi Roguelike shooter! Combine any weapon with any upgrade to customize your arsenal. Form a squad of holographic soldiers, redesign their guns too, and slay hordes of cybernetic enemies!

Start your engines and dive into Drift Survivors! Drift through chaotic top-down arenas, obliterate enemies with unique weapons, and upgrade your ride to survive endless waves. Featuring an exclusive phonk soundtrack.

Stickman's Arena is a top-down arena shooter roguelite where you play a stickman wielding up to 6 weapons at a time to fight off hordes of enemies. Choose from a variety of upgrades and combine your weapons to create unique and game-breaking builds.

Hero Survival is an action-roguelite where you have to shoot down hordes of monsters from classic horror movies one by one to please the Mad Time God. Choose from a variety of skills, weapons, and items to create a unique build for every bizarre character.

Welcome to Slime 3K, an unhinged roguelite bullet-heaven set in the Despot’s Game universe! Build a deck of crazy weapons, grow stronger and devour hordes of pink puny humans as a murderous jelly blob on a warpath of death, violence and pretzels.

Viking Survivors is an action roguelite where you wield ancient weapons and unleash Norse fury on endless waves of monsters. Survive the bullet hell, collect mythic weapons, and prove you're the ultimate Viking warrior in this thrilling survival game.

Mow down countless crops and corrupt critters while crafting game-breaking builds! Pesticide Not Required: Prologue is a bullet heaven, horde survival roguelite with farming elements that offers a myriad of stats and special character traits to create wildly diverse run possibilities.

Rule the seas in intense naval combat! Dodge cannonballs, sink enemy ships, and loot their wrecks to upgrade your vessel. Steer the ultimate pirate ship and dominate the ocean!

At a tavern It is where adventurers come together to form a team to hunt for the bounty of monsters that are dangerous to humans. This is an Action Roguelite game where you build a team and develop a character that people like to swarm with monsters that will flock to your team to crush …or not

Blast through robotic hordes in this arena auto-battler rogue-lite Brotato-like. Use auto-firing weapons and drones, timely dashes and special abilities to reach the Void where a final Conservator awaits convergence. Spend your Cogs wisely within the varied shops to create unique builds!

Sausage vs. Vegetable is a run-based roguelike with bullet heaven elements, following a band of outcast sausages to level up, loot, and fight their way to uncover the truths behind the vegetable invasion.

Summon the Dark Lord for revenge! This game combines survival and roguelite elements, where you summon monsters and place totems to defeat monsters and take down the Dark Lord!

Face hundreds of monsters, upgrade your equipment and try to survive as long as you can. In this Action Roguelite choose from a variety of upgrades, unlock unique characters and create the best build to slaughter everyone in your path!

Rayna Survivors is an action roguelite game where you need to slay hordes of foes and face bosses to learn powerful skills to upgrade your character.