Top similar games like Bioframe Outpost:

Omega Warp is a sci-fi themed action-adventure, which takes place aboard an interstellar freighter. Explore, upgrade your skills and equipment, and uncover the mysteries surrounding the freighter's loss of communication with the base of operations on Earth.

MindSeize is a 2D Metroidvania game set in a Sci-Fi-universe. Transfer your mind to a robot and rescue your beloved one!

Explore a tiny world, find upgrades, discover hidden paths, and battle bosses in this retro-style metroidvania action platformer.

In this Insanely Twisted, 2-D action-adventure game, explore unique environments and battle bizarre creatures.

What if someone knew your mind better than you did? The Swapper is an award-winning, narrative driven puzzle game set in the furthest reaches of space.

Mutant foes await: Transform into different animals and recombine your own DNA to unlock new abilities in Faunamorph. Uncover the mysteries of your origin in this action-packed 2D metroidvania about genetics and mutations.

Pilot your starfighter through a human-inhabited starsystem in this sci-fi Metroidvania. Battle fierce enemies, solve physics-based puzzles, and explore ancient ruins and intricate dungeons. Liberate Illustris and repel the invaders in a decisive final showdown!

Teamwork matters most in this seamless, fantastical metroidvania within a living, breathing world. Realize each character's true potential to take down an invading force of overwhelmingly powerful parasites.

A vibrant sci-fi platform adventure game where you help Maxwell the dog explore unfamiliar worlds, make strange new friends and contend with mysterious forces - by jumping, shooting, slicing, shrinking, warping and drilling.

In 2097, life is discovered on Mars. When your mission of first contact becomes trapped by a cave-in, you must master the alien ecosystem to survive. Soon you stumble upon more than anyone expected, and with time running out, you will make a decision that determines the fate of a lost planet.

Deliver Us The Moon is a Sci-Fi thriller set in an apocalyptic near future where Earth's natural resources are depleted. In an effort to solve the energy crisis, global powers created the World Space Agency and secured a promising new source of energy on the moon.

Revival is a third-person sci-fi action-adventure where you explore a massive hub world, hunt colossal bosses, solve environmental puzzles, and salvage alien technology to repair your ship and escape a hostile planet.

Explore the world of the crystal-mining creatures, the Kryh, Meet other alien races, improve your equipments and customize your burrow. Great adventures are waiting in Kryh Explorer!

Exographer is an exploration game based on science. Become an explorer, stranded in an alien planet, and discover the secrets of an extinct civilization. Gain new powers to avoid dangers and obstacles in your journey, and use your camera to reveal particles and hidden clues.

Beyond Sentinel will have you play as both Justin and Erica in horizontal shooter and metroidvania stages as you battle in space and explore the many levels of the Sentinel station.

You are a robot with the mindset of a child, but your advanced robotic body allows you to fight better than most humans. Your goal is to solve the mystery of how the aliens got aboard the spaceship and, more importantly, to find a new energy source to survive. A strange scientist will accompany you.

Cryselts is a 2D pixel-art Metroidvania focused on exploration, modular suits, and ranged combat, set in a hostile world corrupted by a mutagenic threat. Join the Cryselts, an elite task force designed to protect the planet.

Explore an abandoned space station in this retro-themed explorative action platformer.

Restore your home planet to be the thriving wasteland it once was, in order to reboot everyone you know. Venture out into space, gather resources to fix your home, and piece together the mystery of how (and why) the plants have taken over.

Explore the mysterious island of Kindara in this vibrant 2D action-adventure. Fight and platform your way through jungles, icy peaks, castles, and crystal caverns in a non-linear interconnected world. Adventure awaits!

Explore three distant planets in this retro-inspired 2D metroidvania, developed for the Game Boy Color. Face mysterious creatures, discover powerful upgrades and uncover lost secrets. The fate of humanity is in your hands!

Time is your greatest resource and secrets are your only upgrades. Master an unraveling time loop in this knowledge-based Metroidvania. As the last Weaver, exploit time-altering anomalies and use what you learn to break the cycle. Explore what remains. Uncover the mystery. Perfect the loop.

An atmospheric narrative-platformer about a service robot stranded on a mysterious planet, Planet of the Eyes features a stunning visual mix of puzzle and platforming challenges, an original musical score, and fully voiced audio logs left by another survivor. Explore the mystery of an unknown world.

Help Elara tackle headaches that are way above her pay grade. Together with Luma, a mysterious floating companion, scout the moon Selene, face down ancient threats, crack environmental puzzles, and brave temples that no technical manual could have ever prepped her for.

What do you do if you are the only one left aboard a spaceship? Your team has embarked on a mysterious expedition a few years ago, the ship’s machinery has started acting up and it seems there are ghosts wandering about. Luckily, the black hole above you doesn’t pose any problems…yet.

An atmospheric science-fiction journey across distant alien landscapes. Traverse monolithic structures, solve intricate puzzles, and uncover the story of a lost civilization written among the stars.

Join renegade mechanic Robin and uncover the secrets of a dying planet. Explore a big world filled with intricate puzzles, interesting characters and menacing bosses in a beautiful platform adventure that tells a personal story about faith, purpose and the challenge of helping people.

Awaken as the lone survivor of an abandoned civilization. A sentient prototype failsafe. Automatically activated as the last resort. With the sole mission to seak out and destroy the corruption that has infected the entire planet.

Explore and uncover the mystery of this enormous spaceship by shooting alien creatures in this Sci-Fi Action/Adventure Metroidvania.

Take control of an AI soldier, explore planets, and partake in fast paced combat in The Future Project, a first person metroidvania. Explore distinct worlds, obtain new weapons and abilities, and defeat powerful enemies in humanity's quest to journey the stars.

Speed through a sinister space station to free yourself and fellow aliens from captivity in this 2D fast paced platformer!

Destinesia is a sci-fi metroidvania which you are looking for a new home for humanity. Parkour your way through most dangerous jungles and explore the ancient dungeons. Upgrade your suit with the remains of your ancestors. Reveal the oldest secrets of Homo Sapiens.

Venineth is a single-player game focusing on unraveling the mysteries of ancient alien technology, somewhere in the universe via exploration, platforming, and puzzle-solving, in a dangerous, distant worlds.