Top similar games like Infect and Destroy:

Plague Inc: Evolved is a unique mix of high strategy and terrifyingly realistic simulation. Your pathogen has just infected 'Patient Zero' - now you must bring about the end of human history by evolving a deadly, global Plague whilst adapting against everything humanity can do to defend itself.

A campy, crazy pixelart zombie apocalypse arcade sim where you're the bad guy. Drop your virus and spread it across the globe while you unlock a whole horde of bizarre undead to do your bidding.

Dead Earth is an open world survival game, choose what you want to do in this world, build a small base, hunt for food, survive and explore the open world, play the game your way, ohh... and try to stay off the menu.

Survive the onslaught, manage your ammo, and endure in Final Redoubt, a relentless survival shooter where every bullet, every swing, and every decision counts!

Flesh Eaters is retro style single player RTS zombie survival game with resource gathering and crafting. Zombies are everywhere! You must gather resources to build barricades, upgrade weapons and armour and explore the city under the siege of the dead

The island of Eden-Nadir, has fallen to a vicious mind consuming fungal parasite. Fight through the ashes of humanity to track down the truth behind the infection as one of four playable survivors before the outbreak spreads throughout the world.

Rescue survivors and construct cities in the clouds in this post-apocalyptic simulation and role-playing game. Escape from frenzied zombies and a mysterious mist permeating through the air.

No More Room in Hell 2 is a terrifying 8 player co-op action horror experience. Find your friends in the dark and survive - in a dynamic, endlessly replayable zombie apocalypse.

Can you survive the ultimate zombie apocalypse? Build your deck and take on a customizable Encounter Deck made from Mission, Zombie, Danger, and Location cards. Every choice matters as you face relentless threats in a collapsing world. Adapt, strategize, and prove your survival instincts!

Darkness is coming. How long can YOU survive? Build your base by day, defend it by night. Play in online or local co-op. Stay alive as long as you can.

"Kill Me If You Can" combines RPG, and construction for a survival defense against zombies. Explore by day for growth, and at night, build defenses against incoming zombies. With unique skills per character, control a team, not just one, for dynamic gameplay.

You are the last survivor in a world overrun by a virus. Travel by train to a safe zone, loot abandoned houses, trade what you find, and fight off zombies. Use your earnings to buy fuel and weapons. A single-player, offline survival journey.

Restore power to fragmented island in a post-apocalyptic world in this base building sandbox with more than 1200 items available from start using the starting cave. Rebuild infrastructure, manage resources, and earn the trust of settlements. Trade, loot, or negotiate to survive. Every choice matters

Warranted Humanity is a post-apocalyptic 2D side scroller where choices matter. Fight different infected and rival factions, scavenge, skill up, craft, manage your shelter and other survivors, all in a race against time to ensure humanity’s survival before everyone is irreversibly infected.