Top similar games like Desktop Defender:

Defend the system in Battle Bits! In this 2D game, you are a brave Arroba (@) fighting a computer virus. Face enemies from A to Z and bosses from 0 to 9 using signs as weapons. Use Bits to upgrade and defeat the final boss, 9, in this exciting retro adventure!

Defend yourself in this minimalist one-button incremental defense game. One hit, and it’s over.

Clankers! is a short incremental robot killing game. Kill Clankers, gather money and spend it on weapons and upgrades to stop Clankers from stealing our jobs!

Defend your planet from relentless stream of incoming asteroids in this fast-paced 2D tower defence game. Strategically place defensive buildings and upgrade your arsenal to protect your world from destruction!

Manage a team of three hunters, improve their attributes as you progress through different stages and complete missions. All of this happens in the corner of your screen, allowing you to continue your daily tasks on the computer while the game progresses.

Deep Space Cache is a short & simple semi-idle bullet heaven incremental asteroid miner game.

Karma Keepers is an idle/incremental souls sim where you guide souls, collect spiritual energy, upgrade and automate to keep corruption at bay, and push karma to the max to banish demons.

Protect the Infinite Power Generator by looping around the train tracks! Battle endless waves of enemies in this unique hybrid of auto-battler, survivor, tower defense, idle/clicker gameplay. How long can you survive?

Combine, automate and upgrade programs to amass a fortune! Infiniclick is a relaxing (or not, it's up to you) incremental game in which your goal is to pay an unfair debt with Fun Corp.

Escape from the witch’s mansion! This is a strategic escape game. Use “Mana Reinforcement” and “Magic Potions” to power Claudia up and make your way through the 30 stages of the witch’s mansion to escape to freedom. Will you be able to make it out of the mansion safely and achieve the best ending?!

Super Sanctum TD is a retro-styled Tower Defense game that focuses on strategy, customization and replayability. Build advanced mazes and construct powerful towers to prevent alien hordes from reaching the Core!

A roguelite tower defense where every defeat makes you stronger. Spend gold on powerful temporary boosts, invest gems in permanent upgrades, and push your tower higher each attempt as you fight to survive all 100 waves.

hit bag..crank lever..upgrade moves..Hit Bag...Crank Lever...Upgrade Moves...HIT BAG....CRANK LEVER....UPGRADE MOVES....THIS... IS...PEAK... GAMEPLAY !

Welcome to Solitary Sentinel, a captivating modern reimagination of Space Invaders and Missile Command, where you must defend against constantly evolving enemies by upgrading a single Sentinel. Enjoy simple controls, and deep strategic gameplay as you fend off the relentless onslaught!

Xenosensory is a short incremental game with horror themes. Use your cursor to bust Xenos and save convicts then spend your research points on skill tree upgrades, actions, gadgets, and uncover the true horrifying nature of this space station nightmare.

"Smash Bones" is a unique clicker and idle game. Become the "King of Bones"!

Nodebuster is a short, experimental incremental game about busting nodes and destroying reality.

Tiny Battles is a tactical action auto-battler where battles take place automatically in the arena. Prologue is a demo version of the Tiny Battles game, where 2 of the 5 factions and 3 of the 15 enemy opponents are available to play.

You will select a hero with unique abilities. As you defend your castle, you will earn money and loot. This will allow you to upgrade your castle and recruit AI controlled allies to synergize with and equip them with weapons and relics. You may also choose to allow the AI to control your hero.

Mine, fight monsters, upgrade your gear, obtain rare items, unlock new powers and mine some more in the massive follow-up to the popular title "Haste-Miner 2". Eternamine offers a casual yet engaging gameplay experience, expand your mining empire and discover the secrets that lie beneath the earth.

Gensoukyo is a 2D top-down game set up for the stage. In the peaceful and tranquil Gensoukyo, a little girl with yellow hair who likes to borrow books everywhere has aroused Alice's anger. Therefore, she calls on everyone in Gensoukyo to gather in front of Marisa's house for a battle!!!!

Upgrade your Castle and Unlock new tiers of Skills and Weapons to Defend vs Monsters and Bosses across VARIOUS ZONES! Find Rare ITEMS dropped from monsters and bosses and upgrade them to their full potential! Defeat RAID Mega-Bosses to find LEGENDARY items!

Escape the Cradle is an Incremental RPG with cute pixel art about a foxgirl trying to clear out the dungeon she was born in so she can leave with her mother and explore the outside world. She's animated with Live2d and you restore her hp between runs with headpats!

A nostalgia-infused pixel clicker in a comedy wrapper. 

"In 'Random Core Defense,' acquire and enhance cores using limited resources to withstand relentless enemy onslaughts. Defeat powerful bosses and test your strategy to survive until the very end!"

An endless Tower Defense game of epic Monsters vs evil War Machines. Unlock and upgrade tons of unique elemental Monsters (Water, Air, Earth, and Fire) to defend your home from an infinite swarm of robots. Strategize the most effective placement of Monsters to synergize their elemental abilities.

Greed Knights is a game where your main focus is to grind for weapons and talent points so you can advance in the dungeons.this game works like most of my previous games. It contains automatic battles and your main focus is to train your champion and see him grow.

Endustry is a game about building, exploring and surviving. Build machines and conveyor belts to collect resources. Try to survive with or without enemy waves depending on which game mode you play.

A whispering flame craves souls. With each offering, your resolve strengthens. Fight spirits, collect their essences, and feed a hunger that may never subside in this short active incremental.

StarShipdle is an indie game that runs on your monitor while you do other stuff. You’ll be overseeing a spaceship as it explores the universe, managing upgrades, tracking progress, and following the story.

Mercenary Battlegrounds is an exciting strategy game where you have to fight and defend your base against waves of enemy forces. Immerse yourself in a fantasy world and enjoy a unique combination of tower defense, auto-battler and strategic game mechanics.