Top similar games like S.E.M.I. – Side Effects May Include...:

4-player co-op bullet-heaven Survivor-like set in robot-overrun Berlin: auto-fire ridiculous weapons and choice-of-3 your way to broken builds. Solo works. Friends recommended.

A co-op game where you have no legs. Search different maps and clear trials to appease Gods and earn your freedom - all while a giant, quirky pair of legs hunts you down.

An online co-op puzzle platformer physics game in space! You and your budz suit up and join the experimental astronaut training program. There is no catch. Just survive orbital space stations.. somehow.

YO UP! is a chaotic co-op physics building game where one wrong move can collapse everything. Build unstable towers solo or with friends, climb floating islands, and reach for space... if your tower holds.

Packing Shift is a cozy warehouse online co-op for 1-4 players. Sort the day's deliveries, fill the orders, box them up, and ship them out. Everything is physics-driven, so mind the shelves, mind the rockets, and try not to bury your coworkers under either.

Climb out of the grave and into chaos in this co-op physics platformer set in a cursed Wild West. Blast each other across deadly parkours to survive a world where the only rule is: don't fall.

Chained Together Crossing is a Co-op game where you and up to 4 friends are handcuffed and have to get to the other side of the street. Levels get progressively more difficult, and sanity will be lost.

Climb a ridiculous world of obstacles where one bad jump can send you tumbling back down. Go it alone, race your friends, or get roped together and somehow make it to the Tippidy Top.

Steer the jar with your pickles inside. Roll through trap-filled courses! A 1–4 player physics-based co-op chaos: clear obstacles without shattering the jar, return to checkpoints, and try wild tactics with friends. Easy to learn, hard to master.

Apes together strong. Explosively strong. Gather your friends, pick your grenade, and wreck the arena until you're the only one left standing.

Online co-op for two players tied to the same rolling log. You steer one end, your friend steers the other, so every turn is an argument and every crash has a culprit. The road falls apart behind you. Whatever just happened, it was not your fault.

A co-op destruction game where you and your friends work on a demolition crew under the Grasso Family. Earn cash by destroying procedurally generated, physics based buildings across NJ.

Disaster Crew is a co-op action-adventure for up to four players. Take on unusual contracts, explore locations packed with traps and obstacles, and share an adventure filled with unexpected dangers and spectacular events..

You are a salmon, performing platforming that feels satisfying and ridiculous. Jump off walls, race against your friends, explore the strange world. Most people don't realise how athletic salmon can be.

A bizarre 3D platformer where mold creatures race to escape a nuclear test silo, blasting their rivals and climbing their way to the top.

Shoot magnets, not bullets. Magnetise anything - crates, girders, the friend next to you - then watch matching poles blast apart and opposites slam together. An 8-player online party platformer about climbing one enormous tower, right up until somebody decides you'd look better falling off it.

Team up with up to 5 friends in this scientifically accurate-ish co-op adventure. Play as dung beetles trying to roll your precious dung ball safely home. The wildlife is dangerous, but your friends might be worse.

Rise, knight. Reclaim the skies you were once promised. alone or with up to four friends. Cross ever-changing floating isles, survive chaotic encounters, gather Power, and strengthen your Bonk. Conquer the Aer Isles, or knock each other back trying.

Put on the world's most chaotic circus show in this physics-based co-op party game! Juggle props, ride animals, throw your friends, and pull off ridiculous stunts before the crowd gets bored. Earn XP, unlock new skills, and perform in increasingly challenging arenas.

Two penguins, one snowball. Balance on top of it together and steer it down a mountain of six wild worlds as it grows, melts and sends you flying. Then ride it all the way back up. A co-op physics comedy for two, online or on one PC.

A co-op adventure about driving your Recreational Vehicle home.

Join a fun adventure by rolling a log together! In this 2 player co-op platformer, become lumberjacks with your friend and keep your balance while moving forward on a log. Overcome obstacles by moving back and forth, reach the goal, and never give up. Knowing how to get back up matters.

A crazy co-op run from a hungry monster will test your friendship to the limit! Team up or double-cross each other: lock your friend in a washing machine, dunk 'em in a toilet, or extend a helping hook — all for resources! Between matches, develop your business: a nightclub. Chaos and trash-fun!

Leap, climb, and launch your friends in this chaotic co-op extraction platformer for up to 6 players! Use your drill-wrench to build your way across a vibrant post-apocalyptic world, find replacement parts, and fix broken machines. And if you lose your head, don’t worry: it’s all part of the job.

In this physics-based co-op platformer, you and a friend must carry your short-tempered king through deadly medieval courses. Dodge traps, maintain balance, and work together to reach the throne room. One wrong step, and the king might crown you with his rage!

A co-op game where you and your friends embark on an epic journey to drag the goblin king’s dead body across the kingdom to resurrect him. Use brains, brawn and crazy goblin magic to navigate the tricky terrain and puzzles that lie in your path.

Two pilots, one 30-story Walker, zero coordination. Each of you runs one leg and one arm: stride into the Civic District as one, trade punches with an Ultrafauna, hoist it overhead together and hurl it down the avenue. Then the Ministry of Public Confidence sends you the itemized bill.

Climb, jump, and try not to fall in this chaotic 8-player co-op parkour adventure set in a toy-filled room. Dodge obstacles, use your abilities, and stay on track — because one mistake can send you all the way back down. Try not to lose everything… or each other.

A chaotic co-op climbing race for 2–4 players! Scramble through a floating countryside full of traps, moving platforms, and wild obstacles. A UFO stole your yellow ox — climb higher, shove your rivals, rewind and fast-forward time to carve new paths, and survive to save it.

Carry a fragile power core to its socket with a friend, and don't drop it! Whoever holds it can't jump: throw, catch and keep passing. Swinging cranes, steam jets and crumbling floors stand in your way.

Haul blood, corpses and live specimens back to R&D. MOPCORE is a 1-4 player co-op workplace-sitcom roguelite set inside a bio-research facility. Fight the mutant bugs your manager unleashes and mop up the mess to pass performance reviews and get upgrades. Try not to disappoint your manager!

MINES* is a co-op Minesweeper game where you and your friends walk dangerous terrain armed with a stick, some flags, and questionable judgment. Probe tiles, throw stuff to trigger mines from a distance, and try not to get launched across the board. Solo or with up to 4 friends.

BREAKING NEWS! A giant asteroid is about to destroy the Earth! The Moon is your last hope. Work together with friends to build a tower from everyday objects.

Run, dodge, and launch your way to freedom! Evade angry farmers, collect scrap components across the farm, and construct a makeshift catapult to propel yourself over the fences before you get caught.