Top similar games like Extinction Protocol:

Creeper World 3 is what happens when cellular automata takes over a strategy simulation. Instead of discrete units that attack your base, a fluid-like substance spreads over the terraformable terrain. Your base, your weapons, your strategy... you must adapt them all.

Sheltered is a deep and emotional survival management game. You take on the role of protecting four family members who, after a global apocalypse, have found their way to a deserted shelter. 

Sands of Supremacy is a singleplayer, side-scrolling strategy/resource management hybrid 2D game set in a desert landscape on an unknown, futuristic planet. The game combines survival, strategy, and resource management elements to create a challenging and engaging gameplay experience.

Do you like Tower Defense games with Strategy elements? Well, look no further! We've got exactly what you're looking for! Get ready to defend your settlement from enemies using a huge arsenal of towers!

Scrap Bastion is a strategy tower defense game where you manage your city, equipping it to survive the waves of mutant creatures, testing your planning and decision making capacities at every turn. Watch out, as time is crucial to win!

A brutal godlike village sim that melds the god game, management, and tower defense genres! Fight off hoards of monsters at night, and expand your village in the day time. Inspired by games like Black and White, Rimworld, and Dwarf Fortress but not quite like any of them.

Begin with a handful of survivors after a 17th-century zombie apocalypse and build a growing colony. Shape its organic layout, establish production chains, define ideologies, and pass laws. Thrive by day, defend by night, and test your colony’s resilience against the undead.

Defend your castle from the attacks of the night creatures. Collect coins, interact with the elements of the game, discover, explore, learn and survive for 30 days or try again.

Build, scavenge, craft, and perform occult rituals to survive in a demon-infested, post-apocalyptic colony simulation. Will you survive Judgment day?

Endzone is a post-apocalyptic survival city builder, where you start a new civilization with a group of people after an ecological disaster. Build them a new home and ensure their survival in a shattered world, threatened by constant radiation, toxic rain, sandstorms and droughts.

Survive Tortuga City as a wanted turtle. Defend yourself against the police, build a rebellion, endure dynamic weather, and find an escape route within 50 days before the police deploy their secret weapon.

Set in a gritty, fictional 1960s universe, it’s a colony sim & base-building hybrid where you rebuild a war-ravaged region, fortify your defenses, and control key trade routes that every convoy depends on.

Deep Among the Swarm is a challenging survival RTS roguelite about surviving against thousands of enemies. Drill ever deeper underground while fighting the endless onslaught of the Swarm. Can you save humanity?

The world after a nuclear war. Manage the settlement, learn technology, make decisions, produce weapons, ammunition, organize defense, raid for supplies on other areas, do not let residents die, survive the nuclear winter.

A unique tower defense and RPG game, find new towers, build gold vaults, and defend against monsters. It will be hard to fight against the king monster, you may need to try different tactics.

Irezumi Defenders is a tower defense game where you craft your units in a world inspired by Japanese mythology. Stack cards to craft buildings, gather resources, and build up your defenses to protect your kingdom from Yokai! 👺

Get ready to rethink all your defense strategies! Build barricades to stop monsters, or lure them into a maze and attack. A variety of stages that change each time depending on how you play them.

"In 'Random Core Defense,' acquire and enhance cores using limited resources to withstand relentless enemy onslaughts. Defeat powerful bosses and test your strategy to survive until the very end!"

Until We Die is a side-scrolling strategy game about defending your base where you have to run around as Ivan, assign tasks to people, and fight mutants in the post-apocalyptic subway!

Collect resources and establish a defense line before dark And then Facing countless enemies

Your home town is forced to evacuate: assemble your party, choose a vehicle and grab supplies before hitting the road in search of refuge. Manage your resources and barter, scavenge, hunt or steal along the way to survive in a rapidly warming world filled with hard choices, danger and dysentery.

A brutal survival management simulator set in a post-apocalyptic wasteland. Keep your faction of survivors alive, maintain your shelter and scavenge the ravaged world for resources. Befriend and trade with the factions you meet or conquer them by force.

Farmageddon is a turn-based strategy RPG about farming in the post-apoclayptic desert wastes of New San Fransisco.

Survive! You need resources. Explore and search items to live.

Phoenix Hope is a pixel art 2D real-time, side-view strategy game in which you must develop your colony during the day and repel waves of monsters at night.

This version is only the prologue of the full game. The game supports 1-4 players. Build you homelands in Sanctree, using resources to craft weapons and equipment to fend off underground insects. Dig deeper to explore new worlds, destroy insect nests, and build new defenses to face greater threats.

Breathing life into rusted metal, you alone remain. You, the mysterious golem foundry.