Top similar games like Medusa Frontier:

LithoBreak is a sci-fi survival crafting game packed with resource collection, construction + repair mechanics, orbiting moons, and science-backed simulations. Explore the Aristarchus star system, build complex production systems, and fend of the ever-growing VECS threat.

Red Planet: Survive is a first person survival game for Microsoft Windows. Surviving in the harsh conditions of the Red Planet will be hard, but if you are strong enough, you will succeed. Find the best way to survive, but be careful, since each wrong step will ensure your demise. The environment is your main enemy.

Untethered is a space survival-sandbox set in our own cosmic backyard. Explore zero-gravity environments, build and operate realistic space stations, and fight to stay alive in the unforgiving realm of deep space.

Interstellar Rift is an open world starship simulator with an emphasis on ship construction and multi-player interaction. Survive in a hostile galaxy with your own custom designed and constructed starship. Invite other players to join your crew or fight them across the galaxy!

First Person, Exploring, Surviving, Hunting, Foraging, Buiding, Hoarding, Looting, Prepping, Crafting Work against Time and Survive, Storms, Earthquakes, Nuclear Events, Radical Weather, and much more

Honeycomb: The World Beyond is a survival-sandbox game set on an exuberant planet – Sota7. Explore its vast world and face challenges on your bioengineering journey. Crossbreed plants or animals, gather resources, craft items, and conduct experiments in order to develop new species.

Play as an astronaut on our moon in the future. Your task is to prepare the moon for future colonies by terraforming. Collect resources, explore procedurally generated caves, build buildings and create a second world for you and our earth.

Triton Survival is an open world survival game about exploration, construction, engineering, and fighting on planets. Embark on this interstellar adventure and conquer the galaxy. Are you ready?

You were deep in uncharted space on a research mission. Disaster struck. Together with your friends, explore a mysterious asteroid field and mine whatever resources possible to build what you need to survive.

Abiotic Factor is a survival crafting experience for 1-6 players set in the depths of an underground research facility. Caught between paranormal containment failure, a military crusade, and chaos from a dozen realms, the world’s greatest minds must survive against the universe’s biggest threats.

Raw, real survival in the Pacific. Build a modular floating base. Master realistic sailing mechanics. Face challenging Pacific-like weather & seasons. Hunt, craft, build & navigate using Sun Dial, Sextant & Triangulation. Explore an endless island cluster-based world. Simulate real life scenarios!

A space survival open world terraforming crafting game, designed for 1 to 10 players. Alter the ecosystem of an inhospitable planet to render it habitable for humanity. Survive, gather resources, and build your base. Then, generate oxygen, warmth, and pressure to create a brand new biosphere.

A sandbox survival game, set on life-sized voxel planets with realistic physics with the possibility to shape your own building blocks. From your custom made furniture, walls to vehicle parts. You shape the blocks which can then be used to build buildings, spacecraft and aircraft.

Stars End is a multiplayer sci-fi survival game set hundreds of years in the future in a star system colonized by humans. Come and join us for crafting, construction, missions and PvP on the wild frontier...

INTERASTRA is a fully immersive first-person sci-fi survival adventure game set in outer space. Discover unknown planets differing in weather conditions, resources, and various mysteries. Craft necessary equipment, launch, and control space rockets, explore the universe, and survive among the stars.

An open world survival and automation game. Engineer Alpha combines an infinite editable world, building and connecting of automated machinery, and RPG style player progression.

Starsand is a mystic survival game set among the dunes of an arcane desert. An open-world full of danger, vast environments and mysterious happenings await you! Explore, hunt, craft, build – and SURVIVE.

An open world survival game set in space.

Forever Skies is a first-person post-apocalyptic survival game. Return to Earth, ravaged by an ecological disaster. Fly, upgrade and customize your mobile high-tech airship base. Scavenge resources to survive, face dangers on the surface and hunt for viral pathogens to cure a mysterious illness.

FAR NORTH SURVIVAL is an open-world survival game set in the unique setting of a vast ice-bound area beyond the Arctic Circle.

QANGA: Dive into a sci-fi adventure of exploration and resilience across the cosmos. Merge your mind with a state-of-the-art cyborg crafted by ICLab's Industry labs, and journey through this expansive universe!

100000 years after the apocalypse, a mysterious entity guides you to build a factory on a desert island...

Remains - survival in outer space orbiting the planet. Explore the area. Find a way to restore oxygen. Create tools for your needs. Beware of the dangers of outer space. Build your shelter in orbit and try not to die!

You’ve crash-landed on Earth in 2702. Craft, dig, fight through a vast and colorful post-apocalyptic open world full of wonder, generated cities, dungeons, aliens, mechs, and an underworld. Find love. Or beat the ultimate Underlord!

Northern Lights is an open world survival simulation set in the extreme conditions of the arctic tundra. Clinging to life, you must use real-life survival techniques to gather resources, craft, and hunt while tending to your health and sanity. Can you survive your way out of the mysterious island?

Construct, maintain, manage and upgrade the fleet of your space robots in this sandbox crafter. Build the base, gather resources and automate to succeed in your mission in a unique robotic spacesim.

Set on small procedurally generated planets, PoliPlanet is a unique first-person city building game. Discover new planets, gather resources, craft, explore, and build.

Enchanted Blacksmith is a first-person sandbox where you craft legendary weapons and explore a vast, handcrafted open world. Mine rare ores, gather magical materials, and forge powerful tools to gain fortune and fame. Unlock ancient secrets and become the ultimate master of the forge!

Crash-land onto a unique and hostile alien world and begin your fight to survive. Face its inhabitants, upgrade your technology, create outposts & bases, and find a way to repair your ship. Explore the beautifully strange terrain, all while blasting and crafting your way off of the planet.

ICARUS is a PvE survival game for up to eight players. Explore a savage wilderness in the aftermath of terraforming gone wrong. Survive the Open World, complete timed Missions or build your Outpost. Explore, build, craft and hunt while seeking your fortune and prospecting for exotic matter.