Top similar games like Alchemia: Creatio Ex Nihilo:

Slay your enemies, explore a wicked fantasy realm and unleash crazy combinations of items, artefacts and arcane spells! Break the time loop that grips the Wicked Lands in the ultimate fusion of turn-based tactics, deck-building, and rogue-lites!

Craft demonic essences and brew powerful potions in this diabolical roguelike deckbuilder. Summon 150+ demons to defend your land against heavenly forces. Discover rare relics and ingredients to form the most potent synergies.

Folktale Misfits is the card game roguelike where you play as outcasts looking for answers in a whimsical world. Develop strategies and help the misfit heroes unlock their true potential.

Discover infinite cards in this roguelike deckbuilder. Every card is unique, every run a new experience. Craft, combine, and build your deck completely freely to defeat enemies and bosses, or take on cleverly designed puzzle challenges!

Crownkeep is a roguelike deckbuilder that mixes minesweeper with dungeon crawling. Fight your way through deadly grid-based dungeons with one card in your hand. Build up your deck, forge powerful combos, and defy the madness that devoured the realm.

S.O.S is a roguelike deckbuilder built around blackjack. Collect cards, build your deck, and flip the odds of blackjack in your favor. Face your enemies at the table in Fortuna, the land of demons, and rise to rule the city through perilous pacts and choices.

Craft a legendary deck and lead your troops to protect the Kingdom for the glory of the Han Dynasty in this fast-paced deck-building strategy roguelike. The Kingdom is on the verge of disaster against the Yellow Turbans rebellion, and only you – and your skills as a general – stand in their way!

This isn't a casino. This is war! Command the crew, upgrade your deck and collect rule-bending Booty. Discover devastating combinations and destroy your enemies as you navigate a branching map full of encounters, islands and treasure.

Forge a Resonance with enemy monsters and welcome them into your party. Equip their skills with relics to shape your own battle style, then climb an ever-changing tower as you follow the trail of lost memories in this monster-collecting roguelite turn-based strategy game.

A slot machine deckbuilding roguelike dungeon crawl. Choose a class, grow your symbol deck, unlock spells and relics, and fight your way to the bottom of the Dungeon!

A chance-based roguelike deckbuilder with silly, chaotic dragons. Spin the roulette wheel to multiply your card effects, manipulate the odds, and unleash ridiculous combo turns. Build a synergistic deck, outsmart RNG, and climb your way to the Boss Dragons.

A roguelike alignment deck builder. Where you align your runes to cast spells to defeat enemies. Build your deck and craft your spells to meet the challenges ahead. Feed and grow your companion to aid in battle. Before it's too late, journey to the center of the maze and restore the Pattern Ring.

A unique solo quest card combat adventure with 500+ cards, drafting, roguelike and puzzle modes of play. The campaign features a unique MULTI-CLASSING SYSTEM and 50 boss fights plus hundreds of encounters.

Your world is abruptly erased. Only the Oneiron Expanse remains; a Plane where your mental state evokes lethal potential. Embark on a deckbuilding odyssey where every card is a fragment of your will. Find the Dreamwright and dream your reality back into being... before your memories fade

Fuse cards together in this roguelike deckbuilder to unleash their full potential. Discover powerful fusion combinations, build decks with potent synergies, harness abilities from ancient runes, and defeat challenging enemies on your quest to restore peace to the realm of Erdia.

Atomic Souls is a tactical roguelite deckbuilder which has you playing as an awoken remnant of the old world. Journey through the new world, encounter bizarre creatures, assemble the perfect deck, discover powerful artifacts, and fulfill your destiny!

Poker Quest is a fantasy roguelike where players use a standard 52-card deck to take on fierce enemies in epic battles. Featuring over 20 unique heroes, thousands of items, and deep gameplay that will test even the most experienced players.

Embark on a thrilling deckbuilding adventure, fighting your way to the final boss on a journey that's different every time.

Tactical Roguelike Deckbuilder with ability-based combat, fueled by card synergies. Build a powerful deck to support your hero. Use abilities to wipe out hordes of enemies. Discover powerful combos within the near-endless variety of composite cards.

TAROGUE is a challenging Tarot Roguelike Deckbuilder. You are The Fool. 🃏 Craft your deck, discover synergies, and uncover the secrets of the four factions; Wands, Cups, Swords, and Coins. Dive into the occult and unravel the mysteries of Kings, Queens, and Aces. Welcome to the Courts!

Devise the ultimate spell rotation and watch it obliterate your opponents. In this roguelike autobattler, arrange your spells into devastating combos and customize them with build-defining runestones. Draft spells, sequence your skillbar, slot your runes, and assemble your Broken Build!

Card of Fate is a roguelike deckbuilder where you wander the path to Heaven or Hell. Construct a powerful deck, find legendary relics, and defeat the guardians of the afterlife. Will you master the celestial arts of the Angel or the devastating fury of the Demon?

Through Hell and Back is a timeline based roguelike deckbuilding game. Place your spells on the Timeline to outsmart your enemies. Choose your power ups carefully, trade spells and upgrade the Timeline to unleash devastating combos.

CELESTIAL 9 is a roguelike fusing Teochew lore & 'Mu Shi' poker. Forge pacts with deities! In a deadly gamble challenging the Sunken Sovereigns, use strategy to unleash epic combos and keep your family's last incense burning!

Memoria Arcana is a mystical memory roguelike where hidden pairs become powerful poker hands. Discover game-changing Arcana, craft clever Zodiac combos and overcome strange Curses in endlessly satisfying runs.

Elemental Vanguard is a roguelike deckbuilder where elemental characters, gear, and skills form powerful hands. Build bigger combos, enhance your deck with item cards and relics, stack massive damage multipliers, and crush enemies across a fantastical journey.

A roguelike deckbuilder where you cook your strategy. As a Cook, manage your Hero’s Appetite and Cholesterol, and build powerful combos with food cards and kitchen tools.

Hell Hold’em is a dark turn-based RPG where every encounter is a battle of strategy, manipulation, and survival. Descend into the underworld to rescue an unjustly condemned soul. Face demons in twisted turn-based duels where every hand is a trap. To survive, you'll have to cheat better than they do.

A deckbuilding (kinda) roguelike with Tetris-like unit management and turn-based battles.

Travel back to darker times, and enjoy a roguelike deckbuilder adventure, set in XVI Century. Discover the secrets of alchemy and fight mythical beasts. Hermetica combines card tactical combat and potion crafting, with a unique medieval art style.

A roguelike deckbuilding game about assembling adventuring parties and running an Adventurers’ Guild. Combine hero, weapon, and item cards to form teams that meet each commission’s needs, earn gold and reviews, uncover relics, and build the realm’s most powerful and beloved guild.

Unleash devastating combos with unique dual cards in this combat roguelite deckbuilder. Battle deadly foes, adapt your deck, and conquer the Everglyph Trials.

The 10-rats-in-a-trenchcoat roguelike deckbuilder. Recruit a rag-tag team of rats, craft a curated deck for each, and discover devastating multi-deck combos. Build your team & masterfully pilot multiple unique decks to take down increasingly difficult enemies.

Play quick card duels, open booster packs, discover new cards and build the best deck to face your next opponent. Duel Champions offers a highly replayable singleplayer TCG experience. Ready to duel?

A roguelite deckbuilder where the courageous spit back. Build powerful Companion and Structure synergies, unleash absurd spit combos, and stand up to bullies, bizarre foes, legendary monsters, and the unexpected.

Perfect Teams is a Rogue Like deckbuilder in which you have to assemble a team of three characters, each one with unique cards and unique powers, to explore different universes and fight the corruption caused by the fusion. What will be your Perfect Team ?