Top similar games like Alchemia: Creatio Ex Nihilo:

Slay your enemies, explore a wicked fantasy realm and unleash crazy combinations of items, artefacts and arcane spells! Break the time loop that grips the Wicked Lands in the ultimate fusion of turn-based tactics, deck-building, and rogue-lites!

Folktale Misfits is the card game roguelike where you play as outcasts looking for answers in a whimsical world. Develop strategies and help the misfit heroes unlock their true potential.

Discover infinite cards in this roguelike deckbuilder. Every card is unique, every run a new experience. Craft, combine, and build your deck completely freely to defeat enemies and bosses, or take on cleverly designed puzzle challenges!

Craft a legendary deck and lead your troops to protect the Kingdom for the glory of the Han Dynasty in this fast-paced deck-building strategy roguelike. The Kingdom is on the verge of disaster against the Yellow Turbans rebellion, and only you – and your skills as a general – stand in their way!

An arcane roguelike deckbuilder! Align elemental runes into poker-style magical hands, master rule bending relics, and blessings and cast high scoring spell barrages to climb endless towers.

A unique solo quest card combat adventure with 500+ cards, drafting, roguelike and puzzle modes of play. The campaign features a unique MULTI-CLASSING SYSTEM and 50 boss fights plus hundreds of encounters.

Fuse cards together in this roguelike deckbuilder to unleash their full potential. Discover powerful fusion combinations, build decks with potent synergies, harness abilities from ancient runes, and defeat challenging enemies on your quest to restore peace to the realm of Erdia.

Atomic Souls is a tactical roguelite deckbuilder which has you playing as an awoken remnant of the old world. Journey through the new world, encounter bizarre creatures, assemble the perfect deck, discover powerful artifacts, and fulfill your destiny!

Poker Quest is a fantasy roguelike where players use a standard 52-card deck to take on fierce enemies in epic battles. Featuring over 20 unique heroes, thousands of items, and deep gameplay that will test even the most experienced players.

Embark on a thrilling deckbuilding adventure, fighting your way to the final boss on a journey that's different every time.

TAROGUE is a challenging Tarot Roguelike Deckbuilder. You are The Fool. 🃏 Craft your deck, discover synergies, and uncover the secrets of the four factions; Wands, Cups, Swords, and Coins. Dive into the occult and unravel the mysteries of Kings, Queens, and Aces. Welcome to the Courts!

Tactical Roguelike Deckbuilder with ability-based combat, fueled by card synergies. Build a powerful deck to support your hero. Use abilities to wipe out hordes of enemies. Discover powerful combos within the near-endless variety of composite cards.

Through Hell and Back is a timeline based roguelike deckbuilding game. Place your spells on the Timeline to outsmart your enemies. Choose your power ups carefully, trade spells and upgrade the Timeline to unleash devastating combos.

Travel back to darker times, and enjoy a roguelike deckbuilder adventure, set in XVI Century. Discover the secrets of alchemy and fight mythical beasts. Hermetica combines card tactical combat and potion crafting, with a unique medieval art style.

Unleash devastating combos with unique dual cards in this combat roguelite deckbuilder. Battle deadly foes, adapt your deck, and conquer the Everglyph Trials.

Fight your way through the lands of the magical realm in this turn-based roguelike deck builder. Fight enemies by combining powerful dices on your field, enhance their effects, give them new properties, find magic relics and choose new classes for your hero.

A unique mix of mechanics = 💀 Roguelike + 🎲 Autobattler + 🧠 Tactical battles + turn your enemy into a chicken! 🐥

Play quick card duels, open booster packs, discover new cards and build the best deck to face your next opponent. Duel Champions offers a highly replayable singleplayer TCG experience. Ready to duel?

Perfect Teams is a Rogue Like deckbuilder in which you have to assemble a team of three characters, each one with unique cards and unique powers, to explore different universes and fight the corruption caused by the fusion. What will be your Perfect Team ?

Wizard Hand is a magical deckbuilder game where solitaire meets roguelike. You play solitaire by using your magical cards to uncover dazzling combos and accumulate magical points with the help of enchantments, crafting, and a collection of powerful artifacts.

In Witchcraft, a roguelike deckbuilder, combine cards to refine your deck as you experiment with powerful combos and manipulate card effects. Face interesting foes, strategize to create powerful synergies, explore a magical land with meaningful choices and conjure the ultimate deck!

Fight your way through the lands of the magical realm in this turn-based roguelike deck builder. Fight enemies by combining powerful dices on your field, enhance their effects, give them new properties, find magic relics and choose new classes for your hero.

Wield magical dice and build a team of powerful Chimeras to stop a mysterious evil in this tactical roguelite adventure. As a Chimera Summoner, recruit and create your perfect team of mythical beasts and command them to victory using unique dice mechanics.

The deckbuilding roguelike with no energy – play cards using physical space! Slot cards together, manipulate the shape of your cards, and create overpowered combos to break the game!

Play quick card duels, open booster packs to discover new cards with powerful synergies and build your best deck in this Singleplayer Roguelike Deckbuilder inspired by Trading Card Games.

Create your own cards in this roguelike deckbuilder by cutting and pasting throughout your deck! Journey to the chasms, fighting off dragons and Boviks alike as you manage scarce resources.

Embrace the challenge of a roguelike deckbuilder with unique mechanics from the developers of Faeria and Richard Garfield, creator of Magic: The Gathering™. Build a team of two heroes, unleash powerful combos and defeat the legends of the Roguebook!

LuckLand is a strategy casual game that combines elements such as card building and Roguelike. To achieve ultimate victory, all you need to do is rotate the chessboard. This game does not include any real world currency gambling or micro trading.

A tactical deckbuilding game where you fight enemies, unlock cards, and build your deck before each battle—discard cards to generate energy and control the flow of every fight.

Choose your zodiac hero. Craft unique decks. Collect astral boons. Vanquish corrupted constellations. Ascend through cosmic chaos!

This roguelite deckbuilder is set in the American West. Battle monsters, cultists, and folkloric creatures while searching for gold and the source of the evil within a mine. You choose when to leave, not where to go. Will you play it safe returning to the surface, or risk it all by going deeper?

Deck of Ashes is an adventure game with tactical card combat. One character at a time, lead the cast of antiheroes on a quest for redemption. Explore the cursed fantasy world and hunt down powerful cards. Forge a unique Battle Deck, and crush your foes! Can you rid the world of the Ash Curse?

A Roguelike Deckbuilder with fun card fusion and transformations. Combine different cards to create powerful combos and generate power cells that can be used to unlock special abilities. Collect four identical cells to transform Dala into special forms to take on powerful mythical creatures.

A perfect mix of card game, rogue-lite, and pure wild west mayhem. Explore an ever-changing map, collect cards, and battle enemies. Cards are Bullets and are loaded into the revolver to gun down enemies. Experience .Forty-Five's innovative gameplay for free!

TEKO is an Indie Roguelike Deckbuilder where you have to reach the highest possible score by playing Poker hands, but in an unconventional way: making 3 combos at once.

A tactical roguelike deckbuilder of misfits and monsters. Build your deck, summon your minions, cast your spells and survive long enough to claim the land.