Top similar games like Plague Alchemist:

Miuma is a cozy game about a little, modest bakery with unexpected twists. The game features the significant feat of Kevin, the bakery’s new owner, and his venture within the middle of nowhere of which he calls his home.

A cozy fishing RPG set in a quiet coastal village where every tide brings something new. Fish across rivers, lakes, and open sea, craft your own gear, explore distant islands by boat, and uncover the mystery behind the town's vanishing sandpiper birds.

As Iren, a rookie potion maker, as he begins his first job! Track down the culprit behind the mysterious 'Armis' flower, explore, craft potions, and enjoy a charming fantasy life!

A healing simulation where you deduce villagers' hidden worries through conversation and craft custom magic items to heal them. Change their world with warm comfort in a workshop free from competition or time limits.

A short fishing game early in development :-). Collect fish population samples for WDOE as you rebuild a once great public transportation network with the help of your new REALLY REALLY cool bird friends. Also unlock a bunch of new areas, fishing rods and upgrades!

The first ever life-sim RPG where you play as a Wizard Lumberjack! Fell trees with your axe and magic. Explore a quiet world full of secrets, help villagers with their troubles, and steadily grow stronger as you gather resources and take down more trees.

Inherit your grandmother's cabin and the woods she loved. Forage real mushrooms and botanicals, brew the recipes she perfected, fill the field guide she left unfinished, and tend to the villagers she took care of for 40 years. A cozy game about coming home.

RE: OZMA is a 2D Hybrid Sandbox game, pursues sandboxes that are more accessible with faster action while keeping the collection and exploration elements of the sandbox. Players become an ‘Alien Creature’ and survive, explore and pioneer in vast space.

As you wake up as a different being with no memory of why you are here, you will explore a gorgeous underworld with spirits and unique creatures to help you find the way. Go from the red fields of The Crimson Zone to the vast beaches of The Silver Coast to the final run to Elysium.

🌾 From zero to legendary farmer! 192 crop variants to collect, Purple Star is one in a million. 5-min harvest cycles, fast-paced farming! Upgrade legendary tools, unlock mysterious NPCs. Cozy pixel art meets hardcore collecting — ready?

Forage for wild plants, craft bespoke dishes, and delight your otherworldly clientele in this cosy, atmospheric management game. Hone your craft as you collect special equipment and useful folklore by connecting with the locals or simply relax and seek out stillness in nature.

DAVE THE DIVER is a casual, singleplayer adventure RPG featuring deep-sea exploration and fishing during the day and sushi restaurant management at night. Join Dave and his quirky friends as they seek to uncover the secrets of the mysterious Blue Hole.

A 2D space-fishing idle RPG. Cast gravity lines into nebula-soaked planets, reel in bioluminescent leviathans, and run an automated drone fleet that earns credits while you sleep.

Journey through Eldoria, a cozy RPG with vibrant pixel art. As Starweaver descendants, explore continents to gather Starshards and restore the Heartbloom’s glow and become a legendary Starweaver in this heartwarming adventure.

You wake up on a beautiful island, with no memory of how you got there. Stranded, you and 6 strangers must survive, explore, and make this island your home all while uncovering that mystery. Farm, fish, build a home, decorate, form relationships, and uncover the truth hidden in the mountains.

"Table for None" is a pixelated, bite-sized open world, food truck cooking adventure game. Explore diverse regions, discover new recipes, and prepare meals to manage your food truck!

Inherit a forgotten workshop and master the art of potion making in "Aether Brew"! A cozy, exploration-driven alchemy RPG game where you restore magic and uncover secrets in a mystical world.

Discover prehistoric fossils, carefully excavate dinosaur skeletons, and build your own museum in this relaxing pixel-art paleontology game focused on exploration, discovery, and scientific curiosity.

《仙之气》是一款以体验修仙世界观下的RPG沙盒游戏，游戏概念源自道家思想中的炼气，玩家需要收集和运用各种气息来改造地图和修炼自身，炼制丹药和造物等，同时修补破碎的位面，最终找到或合成仙之气完成飞升。

You run a cantina at the edge of the galaxy. Scour alien planets for rare ingredients by day. Cook up wild recipes and serve the galaxy's most demanding gourmets — the Gastronaults — by night. Part exploration, part management sim, all chaos.

The world of Skygrove is fading. As Sol, chosen by the last remaining starlight, rescue animals, explore corrupted portals, recover lost light, and restore hope to a dying town in this cozy pixel-art fantasy adventure.

Candles aren't eternal, and you need to light them up again to find lost objects in this casual, single player adventure rpg. Get missions, make candles, go on adventure! Those old dark dungeons and caves are waiting you.

Experience a lovely adventuring RPG as a humble herbalist whose home is threatened by an unknown blight. Explore ancient ruins and mysterious depths, brew potent potions, and help people in need. Enjoy the deeply gratifying feeling of gradually restoring the entire realm.

Beyond Blue is a single-player narrative adventure that takes you deep into our planet’s beating blue heart. Explore the awesome wonder and unbounded mystery that exists within the world’s ocean.

Join Jo and Rubi on a cozy archaeology expedition. Sort artefacts, clean up the garden, pull trash from the ocean, and explore a dig site. 19 relaxing mini-games across 3 chapters.

Your forest has a story it needs to finish... and it is calling you to tell it. A 2D pixel art cozy adventure! • Grow herbs for tea and healing • Cure the strange ailments you find in your forest creatures • Solve the mystery of what is changing the forest around you.

In this interactive story set in a world where memories are a source of energy, Arthur must help the townspeople reclaim their past. Along the way he will befriend talking vegetables, explore a magical forest, and uncover the town’s mysterious history.

Shroomlings is a peaceful survival-craft game about building, exploring, and automating life on a remote island. Gather resources, craft machines, and shape the world at your own pace — no combat, no rush, just you and the Shroomlings.

Immerse yourself in a breathtaking virtual reality setting and practice your Disc Golf skills in the comfort of your own home.

Purrfect Collars is a cozy single-player shopkeeping adventure. As a witch, design collars, enchant them with potions, manage your shop and meet interesting new customers! Each collar holds meaning, every cat a story!

Traverse a mythic little realm, use a sword to do battle & evoke sworcery to solve mystical musical mysteries.

Escape the chaos of modern life in Rosewood, a quaint town nestled in the heart of nature. With nothing but a patch of land by the lake and a burning passion for fishing, are you ready to seize the opportunity and build a thriving business that rivals even the biggest city corporations?

A cozy pixel-art life sim inspired by traditional Chinese medicine. Grow medicinal herbs, examine symptoms, read the pulse, diagnose patterns, craft remedies, and care for a village through four seasons and the twenty-four solar terms.

Mineko’s Night Market is a narrative-driven, social simulation adventure game that celebrates Japanese culture and invites players to craft whimsical items, eat delicious snacks, and ultimately enjoy all the cats.

Farm, craft, build, and explore a Beautiful isometric pixel art world. Explore new places and find new biomes to expand your list of items, buildings, and recipes.