Top similar games like Infinite Space III: Sea of Stars:

This "spaceship simulation roguelike-like" allows you to take your ship and crew on an adventure through a randomly generated galaxy filled with glory and bitter defeat.

Captain Gail Pilgrim has been flying starships since she was a kid, ferrying passengers between planets and space stations across the galaxy. She has no reason to expect that this latest trip to Alpha Centauri will be anything special, even if her passengers are a little more diverse than usual....

Blend of planet system exploration, discovery, real time space combat, together with player needing to maintain and upgrade his space ship to overcome numerous obstacles. An experience quite unlike other games in its genre.

WarpVector is an immersive sci-fi roguelike built around space exploration, combat, and navigation. Explore the remnants of an ancient civilization, fend off marauding space pirates, and find a way to save your home planet.

Heat Signature is a game from the developers of Gunpoint where you break into spaceships, make terrible mistakes, and think of clever ways out of them. You take a mission, fly to the target ship, sneak inside, and make clever use of your gadgets to distract, ambush and take out the crew.

Embark on a Sci-fi Roguelike Turn-based RPG with Tactical combat. Become a Captain of a freight ship, deliver cargo through deep space, manage your crew, upgrade your ship, fight space warships, and build your reputation. Every day brings a new adventure. Space shows no mercy.

Ancient Space is a story driven single player real time strategy game where you take command of a fleet embarking on a scientific mission to chart undiscovered reaches of space called ‘The Black Zone’. Overcome overwhelming odds and fight for your life and the survival of your ship and its crew.

Quest Machina is a single-player game that uses generative AI to create a unique adventure on each playthrough. Create your character, add prompts to influence the generation, and explore a world made just for you.

5Min Space Battle is a fast-paced third-person space shooter. Pilot different fighters through intense battles, eliminate enemy threats, and level up your fighter to boost its performance. Each fighter has unique combat capabilities, defining your playstyle in thrilling 5-minute skirmishes.

A space exploration adventure in the purest tradition of roguelike. Featuring procedurally generated solar systems, perma-death and tactical turned-based gameplay!

Out There is an award-winning space exploration game blending roguelike, resource management and interactive fiction.

Beyond The Brink is a top-down spaceship adventure game where you mine, trade, and survive on the fringes of colonized space. Upgrade your ship, explore asteroid fields, face pirates and aliens, and uncover treasures in the dangerous, uncharted reaches of space.

A cosmic bullet-hell roguelike. Holy Justice is an exhilarating arcade shooter where you upgrade your ship with Core Enhancers, create unexpected combinations, discover unique devices at critical moments, and unleash outrageously powerful builds.

Rebel Galaxy is a swashbuckling space adventure, with action-packed combat, exploration, discovery, trade, and “negotiation” with the outlandish denizens at the edge of the known universe.

A first-person space roguelike that dares you to press every button (even the ones you shouldn’t). Your signal is fading… Do you copy?

Explore the galaxy. Unearth ancient technology. Recruit, train and command your crew – or maroon them on a nearby comet to save oxygen. Play as a lost spacefarer in this golden age sci-fi adventure - can you find your path home?

Explore the remains of a dead god as an AI trying to find your way back to your crew. Scavenge equipment, recruit allies and face powerful foes in this sci-fi roguelike adventure.

Step into Cosmic Mart, the space supermarket where the deal of the day is certain death. Wipe out the relentless alien infestation devouring the facility in this frantic action roguelike. Choose your mercenary and survive long enough to reach the sixth floor.

A relaxed roguelike space odyssey in a procedurally generated universe! Travel through a lonely and mysterious cosmos. Customize your ship, explore and survive!

What do you do if you are the only one left aboard a spaceship? Your team has embarked on a mysterious expedition a few years ago, the ship’s machinery has started acting up and it seems there are ghosts wandering about. Luckily, the black hole above you doesn’t pose any problems…yet.

Deliver Us The Moon is a Sci-Fi thriller set in an apocalyptic near future where Earth's natural resources are depleted. In an effort to solve the energy crisis, global powers created the World Space Agency and secured a promising new source of energy on the moon.

The Long Journey Home combines an open world full of galaxies, planets and anomalies with quests and mechanics of a rogue-like RPG. One destination. Endless adventures. Where will this journey take you?

Enter the chaotic world of Exo Helljumper: Descent X, filled with mutated foes and lurking dangers. Combine items and strategy to conquer relentless levels. Face unique foes and formidable bosses, test your cunning and skills, and feel the thrill of battle as you push beyond your limits!

Hunted is a free to play game in which you are the last survivor of an alien invasion, you must attack and destroy alien ovals that try and kill you. You can build, craft, and explore.

One year after the events of Episode I, Captain Pilgrim is once again carrying a shipload of passengers between star systems. This time her guests include a mysterious priestess, a wayward youth and a robotics genius.

Become a space mining astronaut in this chill rogue-lite mining game. Explore, mine and complete objectives while unlocking and upgrading your equipment along the way.

Take control of a starship fleeing the sudden attack on your home world in this single-player sci-fi roguelike. Evade pursuit, manage resources, deal with aliens, and acquire new weapons and technology. Each ship you lead to safety will join the mission to take back the home world.

Endless Sky is a 2D space trading and combat game inspired by the classic Escape Velocity series. Work your way up from a relatively wimpy shuttle, cargo ship, or fighter, to a highly upgraded and customized flagship or to a massive fleet of warships or freighters.

Still reeling from the life-changing events of the previous episode, Gail seeks out a safe haven with her father in the Delta Pavonis system. However, she soon learns that the politics of Planet Leto can be as treacherous and unpredictable as the local weather.

A simple and exciting roguelike TPS shooting game with no learning curve. Upgrade, choose abilities, and keep firing away. Break the loop, explore the secrets of the planet. Combine powerful enhancements and elements to create your unique build, and get stronger in each playthrough.

Locked away in the most secure prison in the galaxy, with little hope of escape, Gail Pilgrim faces the most difficult ordeals of her life. Her only hope lies in trusting those who she has come to regard as her friends.

Distant Worlds is a vast, pausable real-time 4X space strategy game. Experience the full depth and detail of turn-based strategy, but with the simplicity and ease of real-time, and on the scale of a massively-multiplayer online game.  

BroodStar is a classic arcade shmup with roguelike elements. Acquire crazy item combos, encounter strange events and fight challenging bosses on a quest to destroy the living planet, the BroodStar.