Top similar games like Infinite Space III: Sea of Stars:

This "spaceship simulation roguelike-like" allows you to take your ship and crew on an adventure through a randomly generated galaxy filled with glory and bitter defeat.

Captain Gail Pilgrim has been flying starships since she was a kid, ferrying passengers between planets and space stations across the galaxy. She has no reason to expect that this latest trip to Alpha Centauri will be anything special, even if her passengers are a little more diverse than usual....

WarpVector is an immersive sci-fi roguelike built around space exploration, combat, and navigation. Explore the remnants of an ancient civilization, fend off marauding space pirates, and find a way to save your home planet.

Heat Signature is a game from the developers of Gunpoint where you break into spaceships, make terrible mistakes, and think of clever ways out of them. You take a mission, fly to the target ship, sneak inside, and make clever use of your gadgets to distract, ambush and take out the crew.

Quest Machina is a single-player game that uses generative AI to create a unique adventure on each playthrough. Create your character, add prompts to influence the generation, and explore a world made just for you.

Ancient Space is a story driven single player real time strategy game where you take command of a fleet embarking on a scientific mission to chart undiscovered reaches of space called ‘The Black Zone’. Overcome overwhelming odds and fight for your life and the survival of your ship and its crew.

5Min Space Battle is a fast-paced third-person space shooter. Pilot different fighters through intense battles, eliminate enemy threats, and level up your fighter to boost its performance. Each fighter has unique combat capabilities, defining your playstyle in thrilling 5-minute skirmishes.

Beyond The Brink is a top-down spaceship adventure game where you mine, trade, and survive on the fringes of colonized space. Upgrade your ship, explore asteroid fields, face pirates and aliens, and uncover treasures in the dangerous, uncharted reaches of space.

Trapped in the vastness of space as a Life Support AI with no crew. Find your way home by salvaging and upgrading your ship in a sci-fi rogue-like adventure.

Rebel Galaxy is a swashbuckling space adventure, with action-packed combat, exploration, discovery, trade, and “negotiation” with the outlandish denizens at the edge of the known universe.

A first-person space roguelike that dares you to press every button (even the ones you shouldn’t). Your signal is fading… Do you copy?

The Long Journey Home combines an open world full of galaxies, planets and anomalies with quests and mechanics of a rogue-like RPG. One destination. Endless adventures. Where will this journey take you?

A relaxed roguelike space odyssey in a procedurally generated universe! Travel through a lonely and mysterious cosmos. Customize your ship, explore and survive!

What do you do if you are the only one left aboard a spaceship? Your team has embarked on a mysterious expedition a few years ago, the ship’s machinery has started acting up and it seems there are ghosts wandering about. Luckily, the black hole above you doesn’t pose any problems…yet.

The Moon has gone dark, cutting off Earth’s last source of energy. As a lone astronaut, you’ll explore abandoned lunar bases, solve intricate puzzles, and navigate stunning zero-gravity environments. Operate advanced vehicles, uncover hidden truths, and survive in this gripping sci-fi thriller.

Enter the chaotic world of Exo Helljumper: Descent X, filled with mutated foes and lurking dangers. Combine items and strategy to conquer relentless levels. Face unique foes and formidable bosses, test your cunning and skills, and feel the thrill of battle as you push beyond your limits!

Hunted is a free to play game in which you are the last survivor of an alien invasion, you must attack and destroy alien ovals that try and kill you. You can build, craft, and explore.

Become a space mining astronaut in this chill rogue-lite mining game. Explore, mine and complete objectives while unlocking and upgrading your equipment along the way.

One year after the events of Episode I, Captain Pilgrim is once again carrying a shipload of passengers between star systems. This time her guests include a mysterious priestess, a wayward youth and a robotics genius.

Take control of a starship fleeing the sudden attack on your home world in this single-player sci-fi roguelike. Evade pursuit, manage resources, deal with aliens, and acquire new weapons and technology. Each ship you lead to safety will join the mission to take back the home world.

Endless Sky is a 2D space trading and combat game inspired by the classic Escape Velocity series. Work your way up from a relatively wimpy shuttle, cargo ship, or fighter, to a highly upgraded and customized flagship or to a massive fleet of warships or freighters.

Shoot aliens, fly around and make everything explode, alone and with friends, in this frenetic 2D run and gun roguelite. Survive the procedurally generated environment, collect weapons, level up and defeat planetary bosses. Improve between runs and discover new planets as you win.

BroodStar is a classic arcade shmup with roguelike elements. Acquire crazy item combos, encounter strange events and fight challenging bosses on a quest to destroy the living planet, the BroodStar.

The Wreckage resounds with the echoes of countless songs, filling the air of a constantly shifting maze where bravery and sacrifice are key to staying alive. Then, without warning, one song goes silent. Will you step into this dicey labyrinth and uncover its secrets in this minimalist and dark RPG?

Distant Worlds is a vast, pausable real-time 4X space strategy game. Experience the full depth and detail of turn-based strategy, but with the simplicity and ease of real-time, and on the scale of a massively-multiplayer online game.  

Time for your toughest mission yet! Recruit and train your crew to tackle the growing threat from alien and android armies as you defend Earth to become a Galactic Legend in Space Crew: Legendary Edition. All new content free to existing owners of Space Crew!

A single-developer passion project. A seamless full scale solar system. Thrilling action. Be part of an incredible journey as a Universe is built from the ground up!

The ultimate space capital ship combat compendium is the evolution of hard core space combat sims. The only game of its kind currently in existence.

The great battle codenamed 'Operation Zeta' has been lost. Your ship is in shambles and you have to act quickly to collect all of the parts and repair your ship before the warzone is completely destroyed by the enemies death laser in this space rougelike.

Thetawave is a physics-based space shooter with procedurally generated levels, diverse foes, and distinct characters.

What if someone knew your mind better than you did? The Swapper is an award-winning, narrative driven puzzle game set in the furthest reaches of space.

Still reeling from the life-changing events of the previous episode, Gail seeks out a safe haven with her father in the Delta Pavonis system. However, she soon learns that the politics of Planet Leto can be as treacherous and unpredictable as the local weather.