Top similar games like Hand of Hexes:

Tower Deckfense is an exciting blend of tower defense and deck building. Build your deck strategically, upgrade your towers, and equip them with powerful modifiers to discover the best combinations and devastate your enemies.

Crystal Guardians is a tower defense game with rogue-like elements. Fight of waves and defend the world crystal. Gear up your towers with a powerful combination of items for your strategy. In an ever expanding map, find hidden powers and conquer the enemies.

The fusion of deck-building roguelike and tower defense returns, bigger than ever! Build your deck with powerful new cards, unlock unique trinkets, and deploy enhanced towers to overcome relentless waves of enemies and new strategic challenges.

Build twisting mazes with tetromino blocks and deploy unique towers in this strategic roguelite tower defense adventure!

Forest Heroes Prologue combines tower defense with roguelike deck building. Enjoy intense battles and diverse strategies with simple controls!

Build your deck, expand your kingdom, and defend your Haven! Recruit Citizens, construct landmarks, and build powerful combos in this roguelike deckbuilder where each card is a Citizen and each season brings new rewards, new threats, and new choices.

We fused card games and roguelikes together to make the best single player deckbuilder we could. Craft a unique deck, encounter bizarre creatures, discover relics of immense power, and Slay the Spire!

Hex grid, 30 waves of endless night. Build your Six Formations, summon Three Kingdoms heroes, and defend the last stronghold through deckbuilding synergy.

The 10-rats-in-a-trenchcoat roguelike deckbuilder. Recruit a rag-tag team of rats, craft a curated deck for each, and discover devastating multi-deck combos. Build your team & masterfully pilot multiple unique decks to take down increasingly difficult enemies.

Create your own cards in this roguelike deckbuilder by cutting and pasting throughout your deck! Journey to the chasms, fighting off dragons and Boviks alike as you manage scarce resources.

Wield magical dice and build a team of powerful Chimeras to stop a mysterious evil in this tactical roguelite adventure. As a Chimera Summoner, recruit and create your perfect team of mythical beasts and command them to victory using unique dice mechanics.

A chance-based roguelike deckbuilder with silly, chaotic dragons. Spin the roulette wheel to multiply your card effects, manipulate the odds, and unleash ridiculous combo turns. Build a synergistic deck, outsmart RNG, and climb your way to the Boss Dragons.

TAROGUE is a challenging Tarot Roguelike Deckbuilder. You are The Fool. 🃏 Craft your deck, discover synergies, and uncover the secrets of the four factions; Wands, Cups, Swords, and Coins. Dive into the occult and unravel the mysteries of Kings, Queens, and Aces. Welcome to the Courts!

A roguelike alignment deck builder. Where you align your runes to cast spells to defeat enemies. Build your deck and craft your spells to meet the challenges ahead. Feed and grow your companion to aid in battle. Before it's too late, journey to the center of the maze and restore the Pattern Ring.

Forest Heroes combines defense gameplay with roguelike deck-building. Enjoy intense battles and diverse strategies with simple controls!

Dear candidate, start your free probation period as manager of Hell! Punish sinners by using our deck-building system, constructing fiendish towers to manage underworld hordes. Good luck!

A dark 1930s cartoon roguelike deckbuilder fused with real-time tower defense. Turn cards into living towers, survive escalating waves, choose risky routes, buy new cards, and stamp powerful sigils into your deck.

Tavern Defense is a Tower Defense + Roguelike Deckbuilder game where you build your deck of cards, carve your own paths for monsters, and create magnificent synergies to win the game.

Dive into the whimsical world of Tinker Tactics, a unique blend of roguelike deckbuilding and tower defense. Craft the perfect deck to build the most efficient engines for your toy towers, then fend off waves of malfunctioning toy robots.

Carefully craft your Mosaic in this fantasy themed deckbuilding game. Battle by battle, tile by tile, you'll form synergies and build up your Mosaic's combo potential, hoping to beat the curve as you forge deeper into enemy territory.

Take on the elements in Wildfrost, a tactical roguelike deckbuilder! Journey across a frozen tundra, collecting cards strong enough to banish the eternal winter…

In Kingdom’s Path, each battle is your own living battlefield. Every zone you place shifts enemy flow, pushing you to adapt and outsmart them. Towers rise, leaders guide, and no run plays the same. Build, defend, and carve victory from chaos.

A fun roguelike with cards, which differs from the rest in one small detail: for each card you pay with your health. Who will kill you faster, the enemy or yourself?

Facehand is a synergy-driven roguelike deckbuilder with autobattling mechanics. Craft the perfect deck and chain card abilities to create wild combos!

Cubic Cosmos is a thrilling fast-paced roguelike card game. You have been trapped in a deadly game. One wrong move could see you reduced to a plaything of the goddess. Can you free yourself from the endless cycle and escape your fate?

We fused deck-building roguelikes and tower defenses in a way never seen before - deploy your towers, collect valuable trinkets and cast powerful spells to defend yourself against the Salkoth!

These Doomed Isles: The First God is a prologue chapter of the main game, These Doomed Isles. Play as Cernunnos, the Celtic god of nature, and lead the Celtic civilisation to victory against waves of invaders, curses and more!

Hexistence is a Tower Defense Roguelike Deckbuilder. Expand a procedural map, build towers, and cast spells while managing your hand in real time. Optimize your resources to survive increasingly demanding waves!

A roguelike deckbuilder fused with real-time tower defense. Craft your deck, protect your base, slay endless enemies, and survive as long as you can.

Crownkeep is a roguelike deckbuilder that mixes minesweeper with dungeon crawling. Fight your way through deadly grid-based dungeons with one card in your hand. Build up your deck, forge powerful combos, and defy the madness that devoured the realm.

"Plants vs. Animals" is a TD game where players, as plant summoners, collect and upgrade plant cards against animal waves. Victories yield new cards and genetic materials for card mutation and enhancement.Strategic card play and evolution are key

Command a squad of guardians in a thrilling deckbuilding, roguelike card battle to save the world from an Android army invasion. Fight, fall, learn, rise again!

The Rock Paper Scissors game where rules are meant to be broken. Pick an archetype and defeat your foes to become the ultimate champion. Make the crowd go wild at your unfair plays, buy bracelets that will help you get the upper hand, but be careful... Your opponents might be cheating too !

A whimsical roguelike deckbuilder with rich card interactions and deep synergies. Strategize through perilous space missions by assembling powerful crewmates and gadgets. Can you beat your objectives before time runs out?

Combo Card Clashers is a roguelike deckbuilder meets auto battler! Build massive combos by playing all cards each turn. Unlock powerful card synergies, recruit monsters to be your allies, upgrade gears and skills - give it all to brave through a mysterious world.

You are an evil lord with a hero problem and not nearly enough floor space. Draft buildings, pack them into your cramped lair, toil to earn money to expand, create powerful monster synergies, and send your chaotic army of minions to repel wave after wave of heroic do-gooder pests.