Top similar games like Hand of Hexes:

Tower Deckfense is an exciting blend of tower defense and deck building. Build your deck strategically, upgrade your towers, and equip them with powerful modifiers to discover the best combinations and devastate your enemies.

We fused deck-building roguelikes and tower defenses in a way never seen before - deploy your towers, collect valuable trinkets and cast powerful spells to defend yourself against the Salkoth!

Carefully craft your Mosaic in this fantasy themed deckbuilding game. Battle by battle, tile by tile, you'll form synergies and build up your Mosaic's combo potential, hoping to beat the curve as you forge deeper into enemy territory.

Build twisting mazes with tetromino blocks and deploy unique towers in this engaging roguelite tower defense game!

Crystal Guardians is a tower defense game with rogue-like elements. Fight of waves and defend the world crystal. Gear up your towers with a powerful combination of items for your strategy. In an ever expanding map, find hidden powers and conquer the enemies.

"Plants vs. Animals" is a TD game where players, as plant summoners, collect and upgrade plant cards against animal waves. Victories yield new cards and genetic materials for card mutation and enhancement.Strategic card play and evolution are key

These Doomed Isles: The First God is a prologue chapter of the main game, These Doomed Isles. Play as Cernunnos, the Celtic god of nature, and lead the Celtic civilisation to victory against waves of invaders, curses and more!

"Slime Warfare" is a rogue tower defense game with a variety of gameplay and placement.Slimes are weak monsters and always bullied by humans. Players will play the role of the Slime Queen to build structures to defend against adventurers' attacks and strengthen themselves.

Dear candidate, start your free probation period as manager of Hell! Punish sinners by using our deck-building system, constructing fiendish towers to manage underworld hordes. Good luck!

The deckbuilding roguelike with tile-based mana. Strategically position powerful magic sigils, use tile adjacency to create overpowered combos, and seal away the Astral Titans to save the universe from calamity!

This is a game that can be operated and played with just a click, with the goal of earning more money, ensuring that the "weekly" rent in the game can be paid normally, and driving away occasional monsters!

Paper Caper is a rogue-like card crawler with a minimalistic, hand drawn art style. Explore a maze and prepare you deck to overcome the final boss.

Create your own cards in this roguelike deckbuilder by cutting and pasting throughout your deck! Journey to the chasms, fighting off dragons and Boviks alike as you manage scarce resources.

Dear candidate, we are pleased to invite you to take up the position of manager of Hell. You will punish sinners by using our deck-building computer system to construct hellish towers capable of keeping the endless hordes of the underworld in check. Best of luck!

Portal of Defense is a strategy Roguelike tower defense game. The game can complete all operations by simply dragging and dropping with the mouse. Explore the portal and obtain powerful items to become stronger and resist the tide of enemy attacks.

Alchemia is a turn-based strategy roguelike with a hint of puzzle. You'll collect alchemical reagents, building your own personalized combat satchel, and combine them into magical recipes, unique to each run, to battle against outlandish foes.

A perfect mix of card game, rogue-lite, and pure wild west mayhem. Explore an ever-changing map, collect cards, and battle enemies. Cards are Bullets and are loaded into the revolver to gun down enemies. Experience .Forty-Five's innovative gameplay for free!

Embark into a deck-building roguelike where real-time action will challenge your reaction and strategy skills. Face the deadliest criminals in intense turn-based combat, where each card defines the pace of the battle and save the city from the Vegangsters!

LONESTAR is a strategic Roguelike spaceship deckbuilder. As a bounty hunter, you will capture criminals scattered across the universe. Win the shockwave battle to gain rewards and vacations. Find treasures, customize spaceships, unlock talents, defeat the felons and be a legend!

Ruff Ghanor is a Deckbuilder game with Roguelite elements, where each collected card represents a crucial action in your journey. Build the perfect deck, strategize, and create powerful synergies as you progress to face your destiny.

Wild Seasons is a roguelike, deck-gardener. Cultivate a garden that grows mystical cards, orchestrate unique decks as your plants evolve, and coordinate strategic plays across multiple turns to unleash wildly powerful combos!

Start your training in Railroads & Catacombs! Learn how to build your cards in the most effective way. Test your deck against the first boss and master your strategy for the full game.

Build mazes, customize your deck and travel through time, in a nostalgic tower defense game with a minimalist feel and a rogue-lite twist. Only you can save the Tree of Life from the malevolent forces of The Corruption...

Cube Chaos is a complex strategy rogue-lite about placing units to create giant armies, factories, combos, or self replicating murder crabs, overwhelming and outsmarting your opponents. Build and adapt new strategies each run using a ludicrous variety of units, perks and more.

Forest Heroes Prologue combines tower defense with roguelike deck building. Enjoy intense battles and diverse strategies with simple controls!

A cosmic horror roguelike tactical deck builder. Fight nightmarish creatures, add cards to your deck, discover powerful curios and combine all their unique effects in game breaking synergies. Awaken and Hunt the Pale Gods.

Castle Cardians fused card games,roguelike and real time colony defense together. Build your powerful deck, defend the castle and beat invaders.

Test your wits as well as your ability to lead an expedition in this deep space dungeon-crawler. Hire the best heroes and villains of the galaxy. Find unknown planets in uncharted space. Start small, plan big and get a fleet of warships capable enough to rival most fearsome enemies.

On this tranquil island, you will manage your own farm. Grow crops, build facilities, and sell products to earn rent and drive farm growth. Accumulate wealth to purchase permanent land use rights and become the true owner of the farm.

Try to survive in infinite asteroid cloud as long as possible in reworked tower defence style. FInd your own playstyle and beat your own records or chillout with original ambient soundtracks. Build, explore, think - everything to create your own colony in this cold space.

Welcome to a dicey roguelike! Roll, buy, and sell a plethora of crazy dice, scoring hands, and items to tip the scales of lady luck to your favor. Find unique dice that fit your build, and utilize their synergies to dominate each roll.

In Deathless, elements of a collectible card game, roguelike, and turn-based strategy combine seamlessly. Build a unique deck of cards, discover unusual relics, and defeat legendary bosses. No two journeys will ever be the same with endless Path. Crush the Evil and save the world!

A Roguelike Tower Defense game set on a user controlled procedurally generated island. Select unique cards and relics that enhance your towers abilities, crafting powerful builds to defend against the growing hordes of enemies.

Combo Card Clashers is a roguelike deckbuilder meets auto battler! Build massive combos by playing all cards each turn. Unlock powerful card synergies, recruit monsters to be your allies, upgrade gears and skills - give it all to brave through a mysterious world.