Top similar games like Hand of Hexes:

Gattai TD is a roguelike, mazing tower defense in which you merge towers and gain ancient wonders to hold back waves of cursed keepsakes.

Crystal Guardians is a tower defense game with rogue-like elements. Fight of waves and defend the world crystal. Gear up your towers with a powerful combination of items for your strategy. In an ever expanding map, find hidden powers and conquer the enemies.

Tower Deckfense is an exciting blend of tower defense and deck building. Build your deck strategically, upgrade your towers, and equip them with powerful modifiers to discover the best combinations and devastate your enemies.

Build twisting mazes with tetromino blocks and deploy unique towers in this engaging roguelite tower defense game!

Villainous base-builder mixed with inventory management auto-battler roguelike! Draft buildings, pack them carefully into your cramped lair to create powerful synergies and send your army of minions to deal with the endless hero problem. Why won’t they just leave you alone?

Choose wisely as you build the road from your evil tower outwards into the beautiful landscape around it to conquer and claim the region tile by tile in this tower defense deck building roguelike. Hire minions, upgrade your cards, and prepare your defenses against the heroes riding against you.

This is a game that can be operated and played with just a click, with the goal of earning more money, ensuring that the "weekly" rent in the game can be paid normally, and driving away occasional monsters!

Rogue Cube Defense is a minimalist roguelite tower defense game with procedurally generated path that you gradually build up. Each run is different as the upgrades you get from leveling up are random. Pick your towers loadout and come up with the best strategy to beat the hordes of enemies.

Synergize rune traits to give your towers powerful new abilities in this roguelite tower defense! Collect perks, relics, and items you can equip to your towers for unique builds each run!

Iron Crown is a randomly generated Turn-Based deck building with heavy Rogue-lite elements. Following our fellow heroes on their journey players will find random elements to help them reach their randomly generated goal, discover secrets, and claim the Iron Crown.

Cat Guardian is a flexible card game blending tower defense and survival. Manage resources, build, and strategize to protect the Tree of Hope from zombies. Can the cats of Meowx Planet succeed in their mission and survive? It’s up to you!

"Slime Warfare" is a rogue tower defense game with a variety of gameplay and placement.Slimes are weak monsters and always bullied by humans. Players will play the role of the Slime Queen to build structures to defend against adventurers' attacks and strengthen themselves.

Gang of Paws is a Roguelike Deck-Builder with a hybrid turn-based and real-time battle system. Inspired by the amazing Megaman Battle Network.

Rogue Tower is a tower defense game with roguelike elements and a continuously expanding path which you can influence. Unlock, build, upgrade, expand, defend.

Kingdom’s Path is a strategic tower defense, roguelite where you expand the map with random 5x5 zones. Paths, elevations, and tower spots are shaped by your choices. Each run offers new leaders, blueprints, and strategies.

Cards of Prophecy combines Tower Defense, Deckbuilding, and Roguelike elements, with huge inspiration from Trading Card Games. Build an ever evolving deck to summon monsters and use powerful spells. Fuse, defend, open card packs, create new strategies. Repeat.

Gate Guardian is a fantasy roguelite in the horde survival genre. Take advantage of unimaginable freedom in creating your magic spells. Build perfect combinations of skills, change and modify them. Defend Life and Survive Death!

Card Crawl Adventure is a single player card game with light deck building and roguelite elements. Engage in a unique path based combat mechanic to battle against devious tavern bosses. Visit a variety of cozy taverns, collect cards and improve your deck with magic equipment items and charms.

A roguelike deckbuilder fused with real-time tower defense. Craft your deck, protect your base, slay endless enemies, and survive as long as you can.

Castle Cardians fused card games,roguelike and real time colony defense together. Build your powerful deck, defend the castle and beat invaders.

High-speed territory control battle! Build structures, earn money, and grow your army to expand your territory. One King Is Enough is a strategy roguelike deck-building game where you compete against players worldwide in asynchronous battles. Outsmart your rivals with your own powerful builds.

The King is Watching is a roguelite kingdom builder. Rule by the power of your royal gaze! Decide between producing resources, training armies, or balancing both, while adapting to unique events every run

Defend your dungeon against "heroes" in this rogue-lite base defense game. Assign minions, build traps, and mine ores. All in the name of becoming the most profitable dungeon!

This game is a fresh take on tower defense strategy, where it's not just about stacking numbers but engaging in a dynamic play of colors. Change the colors of your towers, enemies, terrain, and magical artifacts to create various offensive and defensive effects through color matching. "Magicolor"

Classic tower defense meets roguelike adventure where you control the hero! Dive into procedurally generated levels filled with unique waves of enemies. Create powerful synergies with a variety of game-changing skills, relics, weapons, and traits to defend your kingdom. Every run is a new challenge!

Tower Lab is a physics-based roguelike tower defense game where strategy meets chaos. Absorb energy from fallen foes, unlock new towers, and synergize your defenses to protect your lab!

Be the mayor of this great old town! Construct buildings, recruit soldiers and send them to war. Will you be able to keep Altwaldheim safe?

Mineral Defense combines tower defense with roguelite elements and procedural generation. Build paths, unlock upgrades, and unleash powerful synergies to conquer evolving challenges in an ever-expanding world.

Become the hero who protects the fantasy world and stop the monster invasion! 'Legacy of Defense' combines defense with deck-building. Build your deck, use powerful skills, gain experience, upgrade, clear stages, and defeat the final boss. Ready to test your strategy and luck?

Carefully craft your Mosaic in this fantasy themed deckbuilding game. Battle by battle, tile by tile, you'll form synergies and build up your Mosaic's combo potential, hoping to beat the curve as you forge deeper into enemy territory.

Welcome to a dicey roguelike! Roll, buy, and sell a plethora of crazy dice, scoring hands, and items to tip the scales of lady luck to your favor. Find unique dice that fit your build, and utilize their synergies to dominate each roll.

Hexguardian is a roguelite, tower defense game where you build your own maps with hexagonal tiles! Build and upgrade towers, recruit armies, learn spells, construct wonders and place hexagonal tiles to create a path to enhance your defenses. With plenty of game modes and talents to unlock!

Embark on a strategic roguelike quest to save the World in Deckbane, a tactical blend of turn-based deckbuilding and poker-powered combat. Collect cards, forge explosive bonds with pets, and play winning hands to unleash devastating attacks!

These Doomed Isles: The First God is a prologue chapter of the main game, These Doomed Isles. Play as Cernunnos, the Celtic god of nature, and lead the Celtic civilisation to victory against waves of invaders, curses and more!

Defend your castle, mine for minerals, and level up your wizarding powers in this thrilling action-roguelike game. Grab your wand and prepare to fight off magical foes in this epic battle for survival!