Top similar games like Hand of Hexes:

Tower Deckfense is an exciting blend of tower defense and deck building. Build your deck strategically, upgrade your towers, and equip them with powerful modifiers to discover the best combinations and devastate your enemies.

Gattai TD is a roguelike, mazing tower defense in which you merge towers and gain ancient wonders to hold back waves of cursed keepsakes.

Build twisting mazes with tetromino blocks and deploy unique towers in this strategic roguelite tower defense adventure!

Crystal Guardians is a tower defense game with rogue-like elements. Fight of waves and defend the world crystal. Gear up your towers with a powerful combination of items for your strategy. In an ever expanding map, find hidden powers and conquer the enemies.

Forest Heroes Prologue combines tower defense with roguelike deck building. Enjoy intense battles and diverse strategies with simple controls!

We fused card games and roguelikes together to make the best single player deckbuilder we could. Craft a unique deck, encounter bizarre creatures, discover relics of immense power, and Slay the Spire!

The 10-rats-in-a-trenchcoat roguelike deckbuilder. Recruit a rag-tag team of rats, craft a curated deck for each, and discover devastating multi-deck combos. Build your team & masterfully pilot multiple unique decks to take down increasingly difficult enemies.

Create your own cards in this roguelike deckbuilder by cutting and pasting throughout your deck! Journey to the chasms, fighting off dragons and Boviks alike as you manage scarce resources.

Wield magical dice and build a team of powerful Chimeras to stop a mysterious evil in this tactical roguelite adventure. As a Chimera Summoner, recruit and create your perfect team of mythical beasts and command them to victory using unique dice mechanics.

TAROGUE is a challenging Tarot Roguelike Deckbuilder. You are The Fool. 🃏 Craft your deck, discover synergies, and uncover the secrets of the four factions; Wands, Cups, Swords, and Coins. Dive into the occult and unravel the mysteries of Kings, Queens, and Aces. Welcome to the Courts!

"Zodiac Mountain" is a roguelike deckbuilder following the journey of a Panda as they adventure to become a Chinese Zodiac. Utilise dual hands of Yin & Yang, encounter fierce mythical characters, outskill your enemies in battle, and climb Zodiac Mountain.

The fusion of deck-building roguelike and tower defense returns, bigger than ever! Build your deck with powerful new cards, unlock unique trinkets, and deploy enhanced towers to overcome relentless waves of enemies and new strategic challenges.

Castella is a Tower Defense Rogue-like, where you will build a fortress to defend yourself from hordes of monsters besieging your castle. During the game you will unlock and upgrade towers and buildings. You will build walls to block the path and defend your resources and town hall.

Forest Heroes combines defense gameplay with roguelike deck-building. Enjoy intense battles and diverse strategies with simple controls!

Dear candidate, start your free probation period as manager of Hell! Punish sinners by using our deck-building system, constructing fiendish towers to manage underworld hordes. Good luck!

Carefully craft your Mosaic in this fantasy themed deckbuilding game. Battle by battle, tile by tile, you'll form synergies and build up your Mosaic's combo potential, hoping to beat the curve as you forge deeper into enemy territory.

A fun roguelike with cards, which differs from the rest in one small detail: for each card you pay with your health. Who will kill you faster, the enemy or yourself?

Facehand is a synergy-driven roguelike deckbuilder with autobattling mechanics. Craft the perfect deck and chain card abilities to create wild combos!

Dive into the whimsical world of Tinker Tactics, a unique blend of roguelike deckbuilding and tower defense. Craft the perfect deck to build the most efficient engines for your toy towers, then fend off waves of malfunctioning toy robots.

We fused deck-building roguelikes and tower defenses in a way never seen before - deploy your towers, collect valuable trinkets and cast powerful spells to defend yourself against the Salkoth!

These Doomed Isles: The First God is a prologue chapter of the main game, These Doomed Isles. Play as Cernunnos, the Celtic god of nature, and lead the Celtic civilisation to victory against waves of invaders, curses and more!

In Kingdom’s Path, each battle is your own living battlefield. Every zone you place shifts enemy flow, pushing you to adapt and outsmart them. Towers rise, leaders guide, and no run plays the same. Build, defend, and carve victory from chaos.

Hexistence is a Roguelike Tower Defense Deck Builder based on four universal elements: Matter, Energy, Space & Time. Place powerful towers and play wondrous spells to defend the Hexspire and restore the Ethereals coming from the Ether!

"Plants vs. Animals" is a TD game where players, as plant summoners, collect and upgrade plant cards against animal waves. Victories yield new cards and genetic materials for card mutation and enhancement.Strategic card play and evolution are key

A roguelike deckbuilder fused with real-time tower defense. Craft your deck, protect your base, slay endless enemies, and survive as long as you can.

Command a squad of guardians in a thrilling deckbuilding, roguelike card battle to save the world from an Android army invasion. Fight, fall, learn, rise again!

A whimsical roguelike deckbuilder with rich card interactions and deep synergies. Strategize through perilous space missions by assembling powerful crewmates and gadgets. Can you beat your objectives before time runs out?

Each start will have a different beginning. The game is set in a cartoon style, with simple and fresh graphics. Players need to deal high damage to defeat their boss through playing cards to clear the level. Suitable for players who enjoy challenges, randomness, and creativity.

Combo Card Clashers is a roguelike deckbuilder meets auto battler! Build massive combos by playing all cards each turn. Unlock powerful card synergies, recruit monsters to be your allies, upgrade gears and skills - give it all to brave through a mysterious world.

In this turn-based roguelike deck-building game, you must recruit troops and use artifacts to repel the gnoll army until help arrives. Every new day the story unfolds, revealing new threats but also surprises. Roll the dice and command your troops to protect the kingdom!

The deckbuilding roguelike with no energy – play cards using physical space! Slot cards together, manipulate the shape of your cards, and create overpowered combos to break the game!

Folktale Misfits is the card game roguelike where you play as outcasts looking for answers in a whimsical world. Develop strategies and help the misfit heroes unlock their true potential.

TEKO is an Indie Roguelike Deckbuilder where you have to reach the highest possible score by playing Poker hands, but in an unconventional way: making 3 combos at once.

Villainous base-builder mixed with inventory management auto-battler roguelike! Draft buildings, pack them carefully into your cramped lair to create powerful synergies and send your army of minions to deal with the endless hero problem. Why won’t they just leave you alone?

A pixel art roguelike deckbuilder battler on a 2D grid. Multiple biomes, randomly generated terrain, and a push-your luck system of battle modifiers keep battles feeling fresh. Characters, cards, stickers, relics, and more create many paths to victory. Join the community's fight to conquer the Grid!

Card Conquest is a Tower Defense game with Deckbuilding and Roguelite elements. Combine spells, towers and units to create a deck and defeat your enemies. Spend your resources wisely and find balance between offense and defense. Gather powerful relics that will enhance your cards.