Top similar games like Slay the Spire:

Destiny or Fate is a deck-building roguelite game. Choose a hero, build a deck and a party of mythical creatures, and set out on an endless adventure! Are you ready to make your own destiny, or will you succumb to an evil fate?

Reincarnation is a medieval/fantasy themed turn-based RPG card game with unique deck-building, character development and class selection experiences. Devise your attack and defense strategies to defeat monsters and gain rewards. Join the action-packed world of Reincarnation today!

Fight through the fog in this sci-fi roguelike deckbuilder where clever positioning, explosive chain-reactions, and the environment itself can make the difference between life and death.

A fast-paced roguelike kingdom builder. Grow your empire and fight massive battles against powerful rival kings. Break the game with thousands of insane builds to become the King of Kings.

All the strategic depth of deckbuilding classics taken to the extreme! Manage combat on a tactical map, pursuing divine boons and avoiding the deadly spread of corruption in Waystones, a turn-based roguelike deckbuilder!

Explore the galaxy in this deckbuilding, sci-fi roguelike where ship upgrades and crew management are key to your survival. Optimize resource generation, engage in intense turn-based battles, and take on ever-growing threats as you seek out The Signal.

Little Adventure tale is a Roguelike Deckbuilder set in a cute fantasy world where you can enlist the help of the Guild to Hire companions and manage several Card Decks & Accept Quests to earn more rewards! All this in order to banish the Evil Lord Obradin!

Neurodeck is a psychological deckbuilding card game to challenge your fears. Build your deck & capacities by answering personality tests, visiting rooms or meditating. Face your phobia and defeat them through the power of life-inspired cards.

Rebuild your kingdom and explore a vibrant fantasy world in this roguelite city builder. Defeat hordes of monsters with a unique team of defenders as you harvest, build, mine, cook, brew, and grow. But if your defenses should fail, be prepared to watch it all burn!

This card game combines elements of roguelike and deckbuilding. During the game, you shall strive ahead, gathering cards to build a unique deck and use it to defeat the enemies getting in your way. You will have to choose between escaping or try to defeat Death, who is relentlessly pursuing you.

Noyah: Corrupted Memories is a roguelike deckbuilder, in pixel art, with random battle generation, day and night cycle, climate events, advanced rune system, that allows you to create endless possibilities with a single card.

Dungeon Decks is a roguelike deckbuilding game where you create custom characters, craft unique decks, and recruit up to 4 allies. Collect powerful party buffs, battle monsters, and choose your own path in procedurally generated dungeons!

Bring revolution to the skies in this party-based deckbuilder with roguelite storytelling. Navigate treacherous sky islands, build unique decks for a crew of unlikely heroes and breach the storm to uncover the true cost of power.

Fight your way through a mysterious dungeon in this deck-building, turn-based roguelike game where you don't use cards, but dice! Deal with enemies by combining powerful dice on your board, boost their effects with magical relics, and risk it all hoping for a good roll on unexpected encounters.

Dreamshard is a rogue-like deck-building game where slay the spire meets hearthstone. Explore procedurally generated dungeons, fight monsters, craft a unique deck and defeat your enemies to find the secret of the Dreamshard.

Unlike other single player deckbuilder, you are going to fill a bag with black and white stones. Wether you can use your skills depends on the order you pick the stones. Build a unique combo, defeat powerful enemies, and don't forget to use your Prescience!

Turn based dice-powered roguelike where strategy and chance collide. Use your rolls to attack, defend, or unleash unique skills as you build your deck ,upgrade your character ,and fight your way from the slums to the top.

Battle your way through a seedy tavern filled with gambling addicted townspeople in this Blackjack Roguelike Adventure. From aces and face cards to tarot cards, business cards and more, create your unique deck to beat the house.

A deck-building roguelite RPG set in a dark and tormented world. Assemble your party and use your cards to survive, fight and build your way through a dark maze of monsters orchestrated by an evil mastermind. Your choices will lead you to judgement.

A roguelike deck-building game where you craft a deck, spark talents, discover runes, and assemble your team with partners' cards! Play unique stories for every character and explore a world caught in the clash of gods. New Puppeteer DLC just released!

Hunt through the wastelands for colossal Beasts in this roguelike deckbuilder. Beware! Beasts grow stronger during battle, allowing them to consume your creatures or counter your spells. Carve profane Gifts from these behemoths and grow stronger to serve your Patron! But serve them to what end?

Lucky Hand is a roguelike deckbuilding game where every card drawn shapes your fate. Build powerful decks, strategize against challenging enemies, and explore dangerous places. With each battle, unlock new cards to help you in your adventure!

Dark Mist is a card game that combines elements of the roguelike deckbuilder genre with enemies that appear in waves. Defeat monsters and level up during battle to keep yourself going.

Become a giant walking dice, explore dungeons and defy Lady Luck in this dice powered roguelike! Now featuring "Reunion", a free DLC with six brand-new episodes!

In Deathless, elements of a collectible card game, roguelike, and turn-based strategy combine seamlessly. Build a unique deck of cards, discover unusual relics, and defeat legendary bosses. No two journeys will ever be the same with endless Path. Crush the Evil and save the world!

A completely new style real-time card battle "Overdungeon" Overdungeon combines rogue-like, tower defense and card games. More than 100 cards are Attack, Animal, Building, Spell, Trap, etc..Build your creative and crazy deck!

Step into a co-op roguelite deckbuilder where courage and strategy define your fate! Unite a team of brave heroes, explore the Forsaken Lands, craft powerful decks, battle strange creatures, and challenge the gods themselves.

Fight your way through an unexplored dungeon in this deck-building, turn-based roguelike focused on dice combinations! Deal with enemies by combining powerful dice on your board, boost their effects with synergies, and risk it all hoping for a good roll.

Iris and The Giant is a fusion of the CCG, RPG and roguelike genres. You play as Iris, who must brave her fears in her imaginary world. Dive into a melancholic and gripping adventure, filled with cute monsters and buried memories. Ready to face your inner demons?

Arcane Veins is a roguelike deckbuilder. Build your deck, chain together spells in your wand, and overpower your enemies as you descend through the darkness uncovering all the secrets the cave has to offer.

Deep in the forgotten corners of the world, a dark force stirs – the Demon King rises once more. Sharpen your wits, seek out powerful artifacts, and stand firm in the face of the apocalypse in this roguelite RPG auto battler.

In this roguelike deckbuilder, you’re hunted by an Eldritch Horror. Build crushing combos, fight coordinated enemies, and reroll your abilities to survive. Infinitely upgrade weapons, forge killer synergies, and become stupidly overpowered!

Ancient Gods is a fusion of hero collector and deck-building rogue-lite where you collect your character, fight, and experience exciting events. Any character can use all the cards, combine them with the character's passive for ultimate power on your exploration.

Northwind is a monster-hunting roguelite deckbuilder with a tug-of-war combat twist, card crafting, and a mana management system inspired by Magic: The Gathering.