Top similar games like Chemical Combat:

Rise of Robots is a Roguelite Shooter where you build a powerful weapon as you fight to survive ever increasing swarms of robots. Stack powerups to create a unique weapon each run and beat the challenge on each map

Dungeon Core is a roguelite top-down shooter where you get to explore the sewers and beyond to ultimately reach an old underground research facility. Old nuclear waste has caused dangerous mutations in creatures due to a failed experiment. You set out to destroy the abandoned nuclear core.

ArrowMongers is a top-down 2D shooter, in a mix between a roguelite dungeon and a level based colosseum! Fight your way through the procedural dungeon while using tons of different arrows, clear the 100-floors colosseum, and become a legendary archer in the ArrowMongers village!

Nether Dungeons is an action-packed dungeon crawler. Battle through procedurally generated dungeons, face relentless enemies, and defeat epic bosses. Customize your hero, wield diverse weapons, and survive intense challenges as you descend into ever-changing, dangerous depths.

Wish Me Well is a roguelike dungeon crawler where you design your own weapon with magic scrolls and fiddle with synergies to fight enemies and unique bosses possessed by ink. Jump into the magic well and save the world of books from ink monsters!

Survive as long as possible in Fried Panic! Buy weapons, abilities, and even donut producing machines. Fight through waves of eggs, lemons, chicken drumsticks, and much more, all in a top down pixel art style.

Plunder magic from the anonymously-owned public internet in this Roguelite Twin-Stick Shooter. Use the essence you steal to research new weapons or augment the ones you already have, to better battle against the network defenses and steal even more power.

Spelltanks is an Action Roguelike where you play as a tank and have complete control over your gun. You can customize it with spells you find inside the dungeons and spells you salvage from enemies. Create your own custom combinations and try to clear the dungeon.

Aspect is a retro-inspired roguelite dungeon crawler, where enemies drop Aspects - fragments of their power, that you can use against them. With a variety of enemies to face, weapons to find, and procedurally generated levels, no two playthroughs are the same. Will you collect all of the Aspects?

Action Roguelike where you build your organism by dividing and placing cells. Pick from random mutations and specialize your cells in one of 11 genes. Test your organism in a fast paced melee- and ranged combat with timing-based parry system against enemies and bosses.

Seedovia is a rogue-lite dungeon crawler where you traverse room after room, fighting challenging monsters. Chain your weapons, collect game-changing passive upgrades, and equip items to create unique builds and become increasingly more powerful.

Your homeworld was destroyed by The Zardians an alien species, and you are the sole survivor. Your missions? Making them pay.

An action-adventure roguelike with a bit of RPG tossed in. Adventure deep into the UnderMine and discover powerful relics, deadly enemies, hidden secrets, and a few friends to help along the way.

Play as the titular Archer Hero in this procedurally generated roguelike, as he sets off to climb the mysterious tower that suddenly appeared one day. Conquer the numerous floors, defeat the monsters that lurk in the shadows and solve the puzzles of this enigmatic tower.

A rogue-like sci-fi Tower Defense strategy game with infinite replayability!

Challenge the Wyld Land! Experience a free-to-play, roguelite, bullet-hell MMO where you band together with others to battle corrupted technological creatures and explore a dangerous world. Dodge waves of bullets, collect powerful gear, explore ever-changing dungeons, and become a legend!

Extinction 1306 is a top-down roguelike shooter. You are the sole survivor after a failed experiment. You must fight off mutant insects, explore the abandoned lab, level up and find upgrades to improve your skills, and defeat bosses to reach a final threat standing in between you and saving Earth.

Roguefall is a action rogue-lite where a lone rogue sets off from a long forgotten ruin to scavenge the sprawling caverns below for artifacts. Fight, explore, collect, and fall until you reach the surface.

Neko's Rage is a pixel art rogue-lite platformer set in a post apocalyptic future overrun with dangerous biomechanical robots. Play as the cyber Neko-01 unit and collect always more loots to upgrade your Hub and character.

A Contusion is a leisurely hardcore top-down roguelite shooter where the hero gets lost in the labyrinths of memory. A variety of weapons, armor and shields, grenades and first aid kits, powerful artifacts and perks will become faithful companions on the path of memories.

Hunt demons as a biker rebel angel in this action-packed rogue-like dungeon crawler. Ride through Forsaken Lands and chase your enemies to the Depths of Hell using blades, guns, spells and support of otherworldly patrons.

Build your ship, escape the swarm, survive for as long as you can. When you are finally defeated, upgrade your technologies to survive longer next time. Escape from Zeta Aurigae is a sci-fi ship builder with rich meta progression.

Microbes and Machines is a roguelite action game where you control a little bubble robot that fights against the forces of evil.

Challenge your enemies by overcoming a simulation in perpetual construction. The Big One is an action/platform game of the "dungeon crawler" type, where your reflexes and concentration will be put to the test.

Time of the Wizard is a Magic Roguelike. Lead the Wizard through challenging combat in a procedurally generated dungeon as you combine the different elements together to create all sorts of fun spells! Dive into a game where every run is unique, every room is dangerous and every death is permanent.

Challenge the tower solo or co-op in this high-octane sky crawler action rogue-lite. Stack power ups and steal destructive weapons as you dodge, dash and mutilate your way to the top. Your retribution awaits.

Slime With A Gun is a fast-paced 2D top-down roguelike shooter where you control a slime with a powerful gun! Craft and merge bullets to create unique, devastating projectiles as you step through time, facing a variety of enemies. Will you survive the chaos and master the art of bullet crafting?

Grid-based action roguelike where you face chaotic encounters against computer viruses. Build and upgrade your antivirus using a vast array of commands and add-ons in order to survive.

Explore a cyberpunk universe where monkeys rule. Challenge the fearsome Cyber Monkeys as you take on the role of a hero armed with a living shark weapon.

Grab your equipment, there are monsters to kill in the deep and narrow dungeons.

Palhalla is a 1v1 rogue-lite shooter with dozens of crazy upgrades! Build your perfect power-up combo in this hectic top-down shooter. Turn the tides with a new power each time you lose - or overcome the odds and defeat your OP opponent!

Catamyst is an Action Roguelike that fuses science and magic to craft potions and throw them at hordes of enemies that threaten the natural world.

Fast paced bullet hell roguelike. Upgrade your weapons and abilities as you collect attribute blocks. Highly customisable with lots of combinations. Fight bosses, pick up items and improve your stats. Unlock new items and achievements for the next run through the ever-changing dungeon.

Reynard is a mixture of procedurally generated action RPG and a Tower Defense genre with roguelike elements. It has been influenced by classics such as The Legend of Zelda and an indie classic - The Binding of Isaac.