Top similar games like Gene Gone Wild:

Slay Goblins is an arena roguelite where you play a knight fighting off hordes of goblins. Choose from a variety of perks, weapons and items to create unique builds and defend your castle.

Slime, Get out! is a fast-paced action roguelite where you battle waves of monsters, collect weapons and upgrades, and create powerful builds. Choose your hero, survive increasingly dangerous enemies, and defeat challenging bosses!

A fast-paced Bullet Hell roguelike where your "hero" is a heavily armored sewage truck. Drift through thousands of enemies, combine dozens of absurd weapons and passive skills. Upgrade your heavy machinery and survive the shift!

Gran Theft Lure is a top-down arena shooter roguelite in which you play as your lovely gran being attacked by hordes of burglars. They can only be killed by luring or pushing them into your garden’s traps. Choose one of the 4 weapon modes, and make them taste theft lure, or should we say failure!

A sepia Roguelike — lead a chained squad through 22 waves. Map events split your line, milestone recruits add firepower. Linked Blink, run upgrades, 19 Evolutions, and a permanent meta tree carry you to the final Boss Hydra.

Brotato is a top-down arena shooter roguelite where you play a potato wielding up to 6 weapons at a time to fight off hordes of aliens. Choose from a variety of traits and items to create unique builds and survive until help arrives.

Blast your way through infinite hordes while completing objectives in this chaotic twin-stick looter shooter with frantic juicy combat. Upgrade gear, recruit heroes, tackle cumulative escalating challenges in your quest for the build of ultimate destruction.

An action-packed roguelite shooter where you battle famous works of art and each level you beat becomes a masterpiece to add to your colorful collection.

Annihilate alien armies, craft devastating builds and traverse hostile biomes in this fast-paced action roguelite! Choose from a roster of vengeful combat robots, each with unique strengths and abilities, and survive relentless alien hordes as you avenge the fall of humanity.

The farm is under attack! Fight against an alien invasion as Hamdy, an armed scarecrow. In this top-down arena roguelike, build your loadout with up to 6 weapons, grow stronger after each wave, and survive until the very end.

Your harvest has a health bar. Defend it as a gun-toting pumpkin in this colorful action roguelite. Dodge monster waves, upgrade your weapons and turn defeated foes into fertilizer. Survive the night, save your crops and unlock your next guardian.

Bullet heaven meets base building in a survivorslike set inside a broken computer. Fight corrupted files, stack upgrades, and place automated helpers that shoot, shield, repair, collect, and trap while you stay alive.

Airships: Lost Flotilla is a steampunk autoshooter where you fight your way through waves of enemies on your way to a safe harbour. Destroy your foes, harvest wreckage, and upgrade your ship.

Choose your race and class, create a unique build, and battle relentless hordes in VERAKORIA. Collect experience, unlock powerful upgrades, defeat deadly bosses, and survive the escalating onslaught in this pixel-art action roguelite.

Flaghead is an arena shooter roguelite where you play as a country, surviving through history from the dark ages into the cybernetic futures and beyond.

Backpack Raiders is a hybrid survival roguelite + tactical inventory builder where how you arrange your gear is just as important as the gear you choose. Build Your Loadout. Outplay the Swarm. Thrive in the City.

Fight endless waves of dumpling enemies and build the most overpowered weapon combinations imaginable. Dodge, upgrade, and unleash ridiculous destruction in this fast-paced survival shooter where every run gets crazier.

A roguelite bullet heaven where you dodge and auto-shoot through waves of enemies. Build devastating weapon, gear and mutation combinations with deep synergies. Face over 30 unique bosses across diverse biomes in this challenging arena shooter.

Fight through neon-drenched survival arenas as a cyber cat-eared gunslinger, stacking weapons, upgrades, and chaotic builds against overwhelming enemy swarms.

A free-form arena-shooter Roguelite with heavy emphasis on building an overpowered character! You play as a little shape that shoots other shapes! Strengthen your character by mixing and matching mods and upgrades, and experiment with a limitless rune upgrade system!

Deck of Potential combines roguelike deckbuilder with bullet heaven. Collect cards, fuse them, and slap on sticker upgrades to beat thousands of monsters. Take down dungeon bosses, unlock new cards, characters, and discover fusion recipes to build the ultimate auto-firing deck.

Blast Beam Bang is a top-down roguelike arena shooter where you upgrade and modify active abilities and weapons between waves to create evolving builds and survive relentless robot swarms.

Assemble your own combat machine from interchangeable components and weapons to mow down hordes of enemies in the arena of this dark cyberpunk survival roguelite. Every part changes your build — combine them to create devastating synergies to survive increasingly brutal waves.

Gacha Fever is a suvivors like in a cute and colorful universe. You will fight waves of monsters with various weapons, from the machine gun to the magical girl wand and the Bubble Tea Canon ! Just be careful of the area !

Blast through robotic hordes in this arena auto-battler rogue-lite Brotato-like. Use auto-firing weapons and drones, timely dashes and special abilities to reach the Void where a final Conservator awaits convergence. Spend your Cogs wisely within the varied shops to create unique builds!

Striving for Light: Survival brings the exploration of infinite expanding skill trees to the arena survival roguelite genre. Unlock new characters, weapons, skills and maps, slay hordes of monsters and take on massive boss fights.

NOWGUN is a top-down, grid-based roguelite. Build your unique skill tree and see how long you can endure. Will your strategy carry you through, or will you fall to the relentless challenge ahead?

Become the galaxy’s deadliest hunter! Wield 7 weapons at once, unleash ricochet chaos, and conquer alien worlds in this fast-paced roguelite. Survive 10 minutes of madness, trigger your Rage, and slay the boss. Master unique Signature Weapons and craft your ultimate build!

A fast roguelite survival chaos where you destroy endless plague hordes, stack insane upgrades, and break the rules of power.

Dustdrifter is an incremental bullet heaven arena shooter. Venture into dangerous ruins, blast through overwhelming hords of enemis and collect valuable relics. Return home to upgrade your drifter and grow your village.

Eight legs, three guns, bullet heaven chaos. Play as a mobster spider in this top-down roguelike shooter, where you tri-wield weapons and stack incremental upgrades to annihilate endless enemy waves.

🍩🔥🤪 Madness meets donuts! Smash Dough Mixers, outgun wild foes, and brave endless mazes in a roguelite rampage!

Legends Reloaded is a roguelike arena shooter where you play as resurrected legends - Alfred Brainstain, Threepac Parkur and Marlin Merlot. Destroy spawners to stop hordes of Lovecraftian aliens, progress through their base to fight the bosses. Get weapons, skills and upgrades to fit your playstyle.

A bullet-heaven action roguelite where every byte counts. Delete hordes of malware, fuse powerful auto-firing programs, and restore corrupted systems. Experience high-octane survival in an executable that fits on a 1.44 MB floppy disk!

Blast Head is a meta progression-focused roguelite/bullet heaven with absurd weapons, powerful runes, and non-linear weapon skill trees. Dive into 10–30 minute runs, discover wild synergies, and unleash chaos across alien arenas.

Build a ring of weapons and fight through 25 waves in a 2D fantasy bullet heaven. Prefer to watch? Let Auto Mode take over. Outside the arena, your hunter lives on your desktop and turns completed to-dos into permanent game progress.