Top similar games like Orbit: Satellite Defense:

After the destruction of the EARTH in 2150, the leaders of the Eurasian Dynasty escaped on board an evacuation fleet. Now they are fighting for the survival of the human species. Their base is one large building comprising of smaller variable parts.

Ancient Space is a story driven single player real time strategy game where you take command of a fleet embarking on a scientific mission to chart undiscovered reaches of space called ‘The Black Zone’. Overcome overwhelming odds and fight for your life and the survival of your ship and its crew.

Battlevoid: Sector Siege is an epic straight into action real-time space strategy game, in which the world has been built to deliver a lively battle field; and the action is never more than just seconds away at the start of every game.

Fight for control of a frontier world. Gather resources, build your base, and command your forces in battle. Survive long enough to unleash your ultimate weapon - THE EPIC.

Empyrean Frontier is an epic real time strategy game that mixes classic RTS gameplay with a multi-stage campaign in which the player commands a fleet of ships through a galactic map. Boss battles, base building, planet destroying superweapons, and tactical skirmishes create a unique blend of genres.

This is more than just an odd looking strategy game, it is a strategy platform. Genetically engineer amorphic creatures & buildings, in real time, in an endlessly open world that adapts to your playstyle. Share, and even battle your designs. How much will they be worth?

Distant Worlds is a vast, pausable real-time 4X space strategy game. Experience the full depth and detail of turn-based strategy, but with the simplicity and ease of real-time, and on the scale of a massively-multiplayer online game.  

Pilot a stolen alien ship in a rebellion against the Archronite invasion. Fly across the archipelagos of your home world and capture enemy bases with the help of your navigation droid co-pilot, DFX-9T. Battle against enemy Arc Vectors, Fighters, Drones and Laser Tanks, liberate your planet, Melos.

Can anyone build an empire in a place like this? Other factions are naturally suspicious of newcomers and may wage war at the first sign of unidentified craft. Here, a natural death is an uncommon luxury.

From the creators of AI War: Fleet Command comes an all-new grand strategy title with turn-based tactical combat, set in a deep simulation of an entire solar system and its billions of inhabitants. You are the last of a murdered race, determined to unify or destroy the 8 others.

Command destructive spaceships to obliterate hordes of enemy vessels, while quickly solving puzzles to weave through networks of vibrantly colorful, adversarial machines!

Battlevoid: Harbinger is a hard sci-fi space exploration game blending roguelike, turn-based, star map strategy, and real-time space battles. You are a young commander venturing out into enemy territories, to unknown galaxies, never knowing what you will face as you jump out from hyperspace.

BAFTA award winning fleet-based RTS meets rogue-lite. In Distant Star: Revenant Fleet, build your fleet of up to 5 ships from a choice of 8 classes and traverse a randomly generated galaxy to defeat the Erebus Platform. NOW AVAILABLE ON MAC AND LINUX

Noble Armada: Lost Worlds is a moddable real-time strategy PC title based on the Noble Armada miniatures game. Set in the Fading Suns Universe, the five Royal Houses dominate human space as they battle each other for control of the greatest resource... humanity itself.

Galactic Ruler offers real time strategy game play at both planetary level and in space! Lead your faction in diplomacy or conquest across a procedurally generated galactic map where any system might hold hostile enemies or resource riches. Develop advanced technologies to rule the galaxy!

ENDLESS™ Space 2 is a Strategic Space Opera, featuring the compelling “just one more turn” gameplay, set in the mysterious ENDLESS™ Universe. As the leader of your civilization, will you impose your vision and build the greatest stellar empire?

Heat Signature is a game from the developers of Gunpoint where you break into spaceships, make terrible mistakes, and think of clever ways out of them. You take a mission, fly to the target ship, sneak inside, and make clever use of your gadgets to distract, ambush and take out the crew.

Counter Terrorist Agency lets you fight international terrorism and prevent attacks all over the world. Use modern invigilation techniques, discover connections, interrogate suspects, eliminate threats and dismantle terrorist networks.

Become a military hacker and help your black ops team reach their goal in this noir cyberpunk tactical game. Scan, hack, overtake, control and manage high tech devices, vehicles and even enemy cyborgs with cutting-edge implants.

Confront the alien invaders head-on, but risk dwindling ammo and their sharpshooting abilities, or take the stealthy path, sneaking around, and seeking hidden vents and passageways to outmaneuver his enemies.

Build amongst the stars in Starport Delta, a light sci-fi strategy game that focuses on survival. Station Commanders across the universe will turn to you for guidance to expand, defend, and survive. Help them build a thriving station, but watch out, there are many dangers hiding in space...

Hyperdrive Massacre is an 80s inspired arcade fragfest in Spacewar sauce designed around local multiplayer, focused on kinestetics, tactical and shooting skills at a frenzied pace.