Top similar games like Immune Response:

Welcome to the world of Polygun, an endlessly customizable hero shooter where you battle against an ever increasing hoard of bloodthirsty shapes! With an array of upgrades to choose from, you'll quickly build from humble beginnings into a hexa-bustin killing machine!

Cyberhunt is a retro procedurally generated twin stick shooter, that takes you back to the sweet to the sweet arcade machines era!

Ore & Ordnance is a Retro styled, Sci-fi, Bullet Hell. Survive endless waves of Pirates, Asteroids and Firestorms. Collect upgrades, complete missions and survive your shift! How long will you last?

GunDeck[100] is a lightning-fast twin-stick shooter where you’ll build your arsenal from randomly-dealt cards. Weapons fire in a rainbow of elements with unique effects. Dart and dodge to survive the fireworks unleashed against you, and retaliate with your own display! Can YOU survive to wave 100?

A neon bullet-hell where the swarm is alive. Outlast escalating waves with pure movement — no cover, nowhere to hide. Just geometry, reflexes, and the void between enemies.

Neon Fighter is a tiny arcade game packed with lasers and explosions, in which every few seconds you are forced to switch weapons automatically, making you have to adapt quickly to the new situation and re-evaluate your perspective.

Fight through immense waves of enemies and test yourself in this difficult, top-down shooter. Swap between short and long-range weapons to tackle any situation. Unlock and upgrade dozens of weapon combinations to customize your loadout. How long can you survive before you get OVERRUN!

Small robot, big battles! Doctor Nanobot is a retro style arcade shooter where you take on bacteria, viruses and more using a variety of high tech medical weaponry!

#Funtime is an explosive twin-stick shooter where shooting isn't your only weapon. Swap your ship's color to destroy enemies, avoid damage, and ultimately control the battlefield.

In Space We Brawl is a frantic couch twin-stick shooter. Get ready for the excitement of pure local multiplayer matches for up to 4 players, including teams. Choose from more than 150 combinations of weapons and ships and conquer maps full of obstacles such as asteroids and black holes!

Chaotic boss-rush, bullet-hell-y, twin-stick arena shooter mayhem! Dynamically changing arena forces you to be vigilant: Watch the bullets, watch the walls!

Test the limits of bio-mechanical clone Model 137 a.k.a BIOTYPE in this free, endless bullet hell. Master the Biotype's patented tri-laser and push as far as you can. Will BIOTYPE prove it can make a difference in the fight against the enemy in the real world?

You've been dropped into enemy space. Weave your Starfighter between alien spaceships, lasers, asteroids and bombs destroying as many as you can and collecting valuable coins and powerups as you go.

Oh no! Anxiety Bot has found himself in a meteor field! Try to help him survive as long as possible in this cozy, laid back arcade shooter. How long can you keep him safe?

A top down, twin stick shooter inspired by classic retro arcade games with loads of enemies, fast paced bullet hell combat, big boss battles and tons of bullets.

Escape the Maze of Malice in this frantic 2D top-down shooter!

Explore the rich vector arcade 'history' of Blue-G Interactive in this enhanced collection of 11 games. The custom engine provides a unique visual style and is made to run fast even on low spec hardware! Watch your step.

Crush, smash, and eat thousands of enemies showing humanity what the meaning of destruction is! Kaiju Catastrophe is an arcade game with roguelite mechanics. Mutate devastating weapons, unlock permanent evolutions, and wreak havoc with a variety of monsters to tear humanity apart!

Fast top-down space shooter with varied missions, relentless enemies, powerful ship upgrades, and most importantly, fire.

Annihilate waves of enemies in this enhanced sequel with better visuals and improved twin stick shooter gameplay.

Dodge, shoot, survive! Polygon pursuit is an arcade-style twin stick shooter where you are pursued by multiple enemies constantly. You play as a lone circle confined in a polygonal world fighting to survive against waves of unique enemies. This is not an easy game.

Don't get swarmed in this incremental top-down shooter! Unlock new mechanics and upgrades as you defeat more and more enemies. Let drones aid you in combat and use your abilities to become unstoppable.

Alpha Force Zero is an intense top-down bullet-hell adventure that requires skill and planning. Utilize multiple weapon systems including an Auto-Turret with adjustable firing modes and unlock upgrades that you can equip in your ship to give you the upper hand. Dodge, fight, survive!

You're stranded in space in an asteroid field. Use your ship to smash through fuel-rich asteroids for points and fuel, and use any power-ups you find along the way. But remember, an empty fuel tank is just as deadly as an asteroid. The void of space is a tough place to be, but you can't stop now.

Defender's Squad is a sci-fi vertical scrolling shooter 2D that combines 7 different levels. Play Solo and pick one of the 3 ships to kill enemies and save the earth from aliens.

Ballistic Tanks is the best tank game you've played since the 80's. Battle in exhilarating local multiplayer, or challenge yourself in an intense solo/co-op arcade mode. Play 5 game modes in over 50 maps; and destroy your enemies in a frenzy of bullets, lasers, and explosions!

Destroy hordes of strange machines that have invaded the forest. Yawnoc is a chaotic top-down shooter roguelite focused on immersion into the world of Conway's Game of Life and other cellular automata.

AREA WARS™ is a fast-paced 2D omnidirectional shooter where you battle enemies from every direction in a constantly changing enclosed area. Defeated enemies trigger chain explosions that engulf nearby foes and boost your score multiplier. Built for short, repeatable runs with score-focused gameplay.

Earth is on the verge of World War 3. All life as we know it will be gone tomorrow. Take control of "Super Star Dan" to build a super SSD that can store every DNA on earth before the world goes up in flames. "Life Saver" is a twin stick shooter that you don't want to miss out on!

Survive endless waves of escalating enemies in this fast-paced arcade shooter. Dodge overwhelming attacks, master precision movement, and fight to stay alive inside hypnotic neon chaos.

Shoot your enemies and try not to let them multiply themselves and turn the game into a chaotic space battle! Space Maxwell is an arcade shooter where your spaceship has the ability to destroy or to multiply your enemies. Climb the leaderboard and try to survive as long as you can!

A modern take on the retro arcade shooter. Super Mega Space Blaster Special is a fast-paced frantic blast of a shoot 'em up (shmup). Played alone or in local coop the game is addictive and will keep you coming back to unlock the next ship or beat your high-score.

XenoFeud is an insane top-down twin-stick arcade alien shooter, where you must survive hordes of alien intruders while defending a mysterious object in space.

Cuboid Keeper is a fast-paced arena shooter with a gripping storyline and an unique spaceship building system. Take control of the legendary Guardian of the Cube and face four advanced civilizations hell-bent on defeating you.

Twinstick shooter! Aim for the highest score before you are finally overwhelemed!

Prove yourself and earn your wings in the Exphelius Championships - a reckless bloodsport of vehicular mayhem across the galaxy Exphelius. Win matches across multiple game modes to earn cash and new parts, upgrade your ships or buy new ones, and claim your way to the top.