Top similar games like Genome Fracture:

Turn the horde into spare parts. Pilot a scrap-built robot in this bullet heaven roguelite, evolve brutal industrial weapons, and rip upgrades from fallen bosses. Build a rolling catastrophe and survive 20 minutes before the junkyard’s final Magnet Sweep.

Project Sundive is wave-based arena auto-shooter roguelite, focusing on ship customization and ridiculously overpowered builds

Fight through neon-drenched survival arenas as a cyber cat-eared gunslinger, stacking weapons, upgrades, and chaotic builds against overwhelming enemy swarms.

A fast-paced sci-fi action roguelite where you battle escalating enemy waves, combine powerful abilities, and take on challenging boss encounters.

move fast → build weapon evolutions | crack elites + bosses | chase a high score | pixel-art bullet heaven | free updates forever

SURVIVE the swarm in this rogue-lite + survivors + asteroids mashup! Exterminate as many alien drones as you can. Upgrade your ship from the crafted deck of equipment and power-ups. You are the Last ship against the Endless... Will your choices be enough to overcome the thousands hunting you?

Slay Goblins is an arena roguelite where you play a knight fighting off hordes of goblins. Choose from a variety of perks, weapons and items to create unique builds and defend your castle.

Starcore Survivor is a top-down arena auto-shooter roguelite. Move, dodge, collect materials, and shape each run through 20 waves of combat, upgrade choices, between-wave shops, weapon fusion, evolution recipes, relics, bosses, and escalating Danger levels.

Defend a central core in a neon geometric survival tower defense. Move and aim your operator, construct fortifications, research permanent upgrades, collect enemy ability modules, face evolving bosses, unlock endless mode, or cooperate online with up to four players.

Bulgasari is a multitasking action roguelike where combat and inventory management happen at the same time. Devour scrap to grow stronger, create your own build, and survive against endless machine hordes.

Your harvest has a health bar. Defend it as a gun-toting pumpkin in this colorful action roguelite. Dodge monster waves, upgrade your weapons and turn defeated foes into fertilizer. Survive the night, save your crops and unlock your next guardian.

Become the galaxy’s deadliest hunter! Wield 7 weapons at once, unleash ricochet chaos, and conquer alien worlds in this fast-paced roguelite. Survive 10 minutes of madness, trigger your Rage, and slay the boss. Master unique Signature Weapons and craft your ultimate build!

Survive massive amount of enemies in space in this top-down action auto-shooter.

Lumbrix is a survivors-like shooter where every segment of your growing worm is both a weapon and a life. Aim your head cannon, shield yourself with your body, evolve your weapons and survive ten minutes to face the boss.

Can you survive the Empire's onslaught? Avoid the attacking enemies and upgrade your ship to last long enough to escape in this space survivorslike.

A bullet heaven (a reverse bullet hell) where your only weapon is the light you see with. Widen the beam to see the swarm coming, or focus it to burn what's close, and go blind everywhere else. Survive to dawn, pick a power, and face a longer, hungrier Night. How many can you last?

In Astrum Vanguard, a 2D horde-survival with bullet hell components, you pilot and upgrade your spaceship to defeat countless alien creatures. Survive the endless onslaught in the cosmic battlefield!

A Bullet-Heaven roguelike in the Approaching Infinity universe with both spaceship and away team missions. The exit of the galaxy's dominant races left a power vacuum that everyone wants to fill. Survive, pick a side, or kill'em all. No time to think when the horde's advancing.

Assemble your own combat machine from interchangeable components and weapons to mow down hordes of enemies in the arena of this dark cyberpunk survival roguelite. Every part changes your build — combine them to create devastating synergies to survive increasingly brutal waves.

Welcome to Solitary Sentinel, a captivating modern reimagination of Space Invaders and Missile Command, where you must defend against constantly evolving enemies by upgrading a single Sentinel. Enjoy simple controls, and deep strategic gameplay as you fend off the relentless onslaught!

An objective-driven bullet heaven where twelve classes build absurd weapon synergies across shifting fantasy biomes. Raise the dead as a Necromancer, plow through enemies as a Knight, and more! Survive events, bosses, and campaign objectives, then chase endless leaderboard runs.

A sepia Roguelike — lead a chained squad through 22 waves. Map events split your line, milestone recruits add firepower. Linked Blink, run upgrades, 19 Evolutions, and a permanent meta tree carry you to the final Boss Hydra.

WARLANCER - Armored Survivor is a top down survivor shooter where you employ weapons within weapons to decimate hordes of enemies with multiple waves of firepower. Configure your mech with upgrades and randomly generated weapons to survive the relentless tide of alien invaders.

Desmarchon is a chain-weaving survivor-like. Burst drifting Anomalies, build your ship through sixteen Campaign operations, then farm thirty Deep Space destinations. Craft gear, insert Reality Manifolds, and push a shared Depth frontier as far as your build can carry you.

Manage your shields, evolve your ship, defend Earth. Nano Squadron is a top-down space roguelite where every run brings new upgrades and every mistake leaves you exposed.

Build your starship and become a fleet-destroying war machine in this sci-fi survivors-like. Discover powerful weapon and augment combinations, battle through enemy swarms, and choose your route through a changing galaxy to destroy the enemy flagship!

Join a roguelike action where cute immune cells battle viruses. Collect data in fast-paced combat, gain weapons and abilities through evolution, or level up to grow stronger. The fun of building your own super immune cell with different combinations each run is up to you!

Fight hordes of Covenant & Flood in this new game mixing Roguelite & Bullet Heaven for hours of mindless fun!

Slime, Get out! is a fast-paced action roguelite where you battle waves of monsters, collect weapons and upgrades, and create powerful builds. Choose your hero, survive increasingly dangerous enemies, and defeat challenging bosses!

SWARMED is a fast-paced arena roguelite where you dual wield guns, mix ammo types, dodge hostile swarms, and stack upgrades into ridiculous builds. Survive all bosses in ~15 minute runs, then keep going in Endless Mode.

Geometry Nexus is a neon action roguelike where your weapons fire automatically. Dodge enemy swarms, collect upgrades, trigger Overdrive, grow stronger between runs, and survive ten minutes to defeat the Nexus Guardian.

A top-down bullet heaven where an old man defends his moss garden from hordes of punks using the power of moss. Survive 15 minutes of escalating chaos, then grow your bonsai between runs — a full bloom grants a charm to help your next attempt.

Bullet heaven meets base building in a survivorslike set inside a broken computer. Fight corrupted files, stack upgrades, and place automated helpers that shoot, shield, repair, collect, and trap while you stay alive.

The frontier has a monster problem, a bandit problem, and apparently a "your life expectancy" problem. Survive the horde, loot the General Store, and die with style. Refunds not available. Neither is mercy.

Blast through hordes of mechanized enemies with spells and upgrades in this roguelite game. Choose your hero and delve into a sprawling skill tree, unlocking devastating magic attacks and obtaining powerful upgrades.