Top similar games like Genome Fracture:

A fast-paced sci-fi action roguelite where you battle escalating enemy waves, combine powerful abilities, and take on challenging boss encounters.

Fight through neon-drenched survival arenas as a cyber cat-eared gunslinger, stacking weapons, upgrades, and chaotic builds against overwhelming enemy swarms.

move fast → build weapon evolutions | crack elites + bosses | chase a high score | pixel-art bullet heaven | free updates forever

An objective-driven bullet heaven where twelve classes build absurd weapon synergies across shifting fantasy biomes. Raise the dead as a Necromancer, plow through enemies as a Knight, and more! Survive events, bosses, and campaign objectives, then chase endless leaderboard runs.

Slay Goblins is an arena roguelite where you play a knight fighting off hordes of goblins. Choose from a variety of perks, weapons and items to create unique builds and defend your castle.

SURVIVE the swarm in this rogue-lite + survivors + asteroids mashup! Exterminate as many alien drones as you can. Upgrade your ship from the crafted deck of equipment and power-ups. You are the Last ship against the Endless... Will your choices be enough to overcome the thousands hunting you?

Starcore Survivor is a top-down arena auto-shooter roguelite. Move, dodge, collect materials, and shape each run through 20 waves of combat, upgrade choices, between-wave shops, weapon fusion, evolution recipes, relics, bosses, and escalating Danger levels.

Defend a central core in a neon geometric survival tower defense. Move and aim your operator, construct fortifications, research permanent upgrades, collect enemy ability modules, face evolving bosses, unlock endless mode, or cooperate online with up to four players.

Become the galaxy’s deadliest hunter! Wield 7 weapons at once, unleash ricochet chaos, and conquer alien worlds in this fast-paced roguelite. Survive 10 minutes of madness, trigger your Rage, and slay the boss. Master unique Signature Weapons and craft your ultimate build!

Survive massive amount of enemies in space in this top-down action auto-shooter.

Can you survive the Empire's onslaught? Avoid the attacking enemies and upgrade your ship to last long enough to escape in this space survivorslike.

A bullet heaven (a reverse bullet hell) where your only weapon is the light you see with. Widen the beam to spot the swarm coming, or focus it to burn what's close, and go blind everywhere else. Survive to dawn and pick new powers. Every night is longer and hungrier than the last.

A Bullet-Heaven roguelike in the Approaching Infinity universe with both spaceship and away team missions. The exit of the galaxy's dominant races left a power vacuum that everyone wants to fill. Survive, pick a side, or kill'em all. No time to think when the horde's advancing.

Mow down endless hordes of enemies in the arena of this dark cyberpunk survival roguelite. Play as a fully modular robot, snapping together multiple weapons and components to craft your perfect build. Collect powerful items to forge game-breaking synergies and annihilate everything in the Pit.

KING ALONE is a Survivors-like, Skill & Equipment building game with Online activities. Perfect your King’s build and find a way to cut through thousands of enemies in a single run. As King, your abilities and decisions are crucial - but it’s your skill that will carry you furthest.

A cyberpunk survivors-like bullet-heaven roguelite set inside a corrupted computer. Dodge endless malware hordes, auto-blast alpha packs and system bosses, loot socketed gear and evolve game-breaking weapon synergies, then raid vaults and extract alive to keep your haul.

In Astrum Vanguard, a 2D horde-survival with bullet hell components, you pilot and upgrade your spaceship to defeat countless alien creatures. Survive the endless onslaught in the cosmic battlefield!

Welcome to Solitary Sentinel, a captivating modern reimagination of Space Invaders and Missile Command, where you must defend against constantly evolving enemies by upgrading a single Sentinel. Enjoy simple controls, and deep strategic gameplay as you fend off the relentless onslaught!

Outlast the onslaught in a sci-fi survivors-like where your decisions matter as much as your firepower. Command customizable starships, enhance your arsenal with 100+ strategy-defining upgrades, and annihilate endless fleets of cosmic combatants! Carve your legacy among the stars or die trying!

WARLANCER - Armored Survivor is a top down survivor shooter where you employ weapons within weapons to decimate hordes of enemies with multiple waves of firepower. Configure your mech with upgrades and randomly generated weapons to survive the relentless tide of alien invaders.

A sepia Roguelike — lead a chained squad through 22 waves. Map events split your line, milestone recruits add firepower. Linked Blink, run upgrades, 19 Evolutions, and a permanent meta tree carry you to the final Boss Hydra.

Manage your shields, evolve your ship, defend Earth. Nano Squadron is a top-down space roguelite where every run brings new upgrades and every mistake leaves you exposed.

Join a roguelike action where cute immune cells battle viruses. Collect data in fast-paced combat, gain weapons and abilities through evolution, or level up to grow stronger. The fun of building your own super immune cell with different combinations each run is up to you!

Fast paced Top-down shooter! Smartly use IRCM to evade the constant barrage of bullets and missiles and destroy everything that stands in your way.

Fight hordes of Covenant & Flood in this new game mixing Roguelite & Bullet Heaven for hours of mindless fun!

SWARMED is a fast-paced arena roguelite where you dual wield guns, mix ammo types, dodge hostile swarms, and stack upgrades into ridiculous builds. Survive all bosses in ~15 minute runs, then keep going in Endless Mode.

Geometry Nexus is a neon action roguelike where your weapons fire automatically. Dodge enemy swarms, collect upgrades, trigger Overdrive, grow stronger between runs, and survive ten minutes to defeat the Nexus Guardian.

Bullet heaven meets base building in a survivorslike set inside a broken computer. Fight corrupted files, stack upgrades, and place automated helpers that shoot, shield, repair, collect, and trap while you stay alive.

The frontier has a monster problem, a bandit problem, and apparently a "your life expectancy" problem. Survive the horde, loot the General Store, and die with style. Refunds not available. Neither is mercy.

Blast through hordes of mechanized enemies with spells and upgrades in this roguelite game. Choose your hero and delve into a sprawling skill tree, unlocking devastating magic attacks and obtaining powerful upgrades.

Pilot powerful combat ships in this 3D space action roguelite. Face ever-growing enemy hordes, collect experience, install modules, create devastating builds, and survive intense battles against minibosses and bosses across hostile regions of space.

Global Agent is a top-down roguelite action game in which you explore and save a world plunged into chaos by a mysterious plague. Step into the role of one of several agents, each of whom develops their own unique special abilities. Fight, plan your journey, and overcome the epidemic.

PhaigeX is a fast-paced "Bullet Heaven" space shooter, tasking the player to explore space sectors and contain a rising incursion of rogue AI-controlled units. Pilot a variety of ships, call in the support craft, and use a myriad of upgrades to lay down heavy firepower towards the enemy forces.

A gross-out horde-survivor where you play the pest. Buzz over picnic tables and sewer guts, stack six revolting weapons, evolve them into screen-clearing monstrosities, and outlive the entire insect kingdom. Die, mutate at The Heap, and go again.