Top similar games like Siege of Centauri:

Marrowsteel is a tower defense roguelite in a grim sci-fi world. Build towers from modules. Unlock. Upgrade. Hold the line against the swarm.

Build the route. Break the machines. Recover your stolen energy cores. CENIZA is a 3D tower defense set in an industrial wasteland, with 100 waves, seven upgradeable tower families and colossal robotic bosses. Reshape the battlefield, then make it your own with mods.

Classic Tower Defense meets space exploration. Build turrets on mining platforms, harvest enemies to build more defenses, and mine Dark Energy to travel the stars. As a sentient AI, you must upgrade your tech, scan planets, and find a new home for humanity before Earth fades away.

Scrappy TD is a steampunk tower defense game with co-op and PvP modes. Place towers, build mazes, and outsmart foes. Play solo or challenge your friends in several game modes.

Rise of Mutant Swarms is a strategy survival tower-defense game where you defend the base against waves of evolving mutant enemies. Place and upgrade turrets, adapt to enemy abilities, and make critical decisions as the pressure rises with every wave.

Cubic Annihilation is a fast-paced RTS that demands skill and tactical thinking. Build your own faction by crafting a custom loadout of units, structures, and modifiers, then command cubic armies across land, sea, and air in tight, real-time combat.

Join our machine legion to conquer the world.

A planetary tower defense where enemies attack across land, air, and space. Build layered defenses, manage resources, and survive an escalating alien invasion.

Do you like Tower Defense games with Strategy elements? Well, look no further! We've got exactly what you're looking for! Get ready to defend your settlement from enemies using a huge arsenal of towers!

Take on the role of commander and protect Earth from the relentless Drone invasion in this exciting tower defense game. Strategize and strengthen your defenses by utilizing a variety of towers, abilities, and elemental upgrades. It's up to you to lead the charge and save humanity from destruction.

Defend your base by placing towers strategically, forming interconnected systems that depend on one another. Adapt your strategy to different environments and enemy waves, exploiting their weaknesses. In System Status: SuperCritical, resources are scarce and critical failure is always an option.

Lead the Mobile Infantry in this RTS game set in the Starship Troopers film universe. Balance your army composition with a diverse set of unit types, overcome line-of-sight and line-of-fire challenges through tactical positioning, and use special abilities to smash the Arachnid hordes!

Battle for galactic dominance in this real-time 4X strategy game with unrivaled scale! You’ll explore, expand, exploit, and exterminate through military force, diplomacy, trade, culture, influence, and other underhanded tactics.

Fight a relentless fluid enemy in this mix of tower defense and real-time strategy. Build your base, grow your forces, and unleash massive firepower to reclaim vast flooded worlds. Face Creeper types with different physics, deploy experimental technology, and create your own maps and units.

Build your towers, plan your efforts, watch out for changing paths and strike back against the alien invaders in this challenging tower defense game!

Build towers, unleash ultimates and command six heroes in sci-fi tower defense. Play all 100 Scenario stages free. Try one-minute highlights of Basic and GRID COMMAND before purchase, then take your aerial fleet into GRID COMMAND's survival battles.

Equip your mechs, drop them from orbit and hold the line. NEEDLEFALL is a horde defense RTS for 1–4 players. Build pipes to carry Flux to the Core and your turrets, raise walls, command your mechs against swarms of hundreds of creatures and destroy the twelve hives.

Thousands of rift creatures. One base. Aim every turret's line of fire, then take the main cannon into your own hands. Take down five bosses across 15 maps, grow stronger between runs, and climb the global leaderboard in Endless. Build and share your own maps on the Workshop.

Assume control of an evil intergalactic megacorporation in this sci-fi tower defense. Build a mining infrastructure on alien moons and exoplanets, exploit their precious resources, and defend your operation against defiant natives.

The last days of man are at hand.. Two years after the Infinite War the once great warring nations now lie in ruins, and humanity’s hope for a brighter future is nothing but a bitter memory. A new, seemingly unstoppable enemy, supported by the zealots of The Order, now seeks to eradicate mankind: UEF, Aeon Loyalist, and Cybran alike.

Earth fell to the alien hive. Build your defense across 16 hand-crafted maps, lead 12 heroes into battle, and take your base online — rival commanders attack it while you're away, and you strike back in seasonal PvP leagues.

Rule the battlefield from orbit! Crystal Nexus: Alien Siege is a hybrid deckbuilding tower-defense game that puts you in charge of outposts on hostile alien planets. Look down on the battlefield from your space station and deploy towers, weapons, and buffs from the cards you’ve collected!

Overgrid is a tactical tower defense game where capturing the territory is just as important as defending it. Build and upgrade your defenses, capture strategic locations, and unlock new technologies across a 30-mission campaign set in the middle of a war between artificial intelligences.

Lead an unlikely team of commando scientists behind enemy lines to fight Nazis, uncover arcane mysteries, and wield experimental technology to turn the tide of WWII in this real-time tactical stealth adventure.

An atmospheric tower-defence strategy game about holding back an oozing toxic Tide. A distant mining colony has awakened a living flood that seeps from breaches in the ground. Dig for resources, raise defensive terrain, and burn your way to seal the breaches. Can you survive the Biletide?

On planets occupied by robots, mine resources and escape while fending off their attacks! The Ark's survival is entirely in your hands. Many elite crews with abilities will assist you in your mission. The various turret modules are always doing their best to defend your base without your attention.

Taur is an action-strategy sci-fi game. Control the Prime Cannon and unlock all of its powerful weapons and abilities. Build turrets, droids, aircraft and more as you fight to protect the homeworld of the Tauron droids against a relentless invasion. Will your Taur stand against the Imperion warmachine?

Command humanity’s last defenses in a cinematic sci-fi tower defense game. Build tactical towers, upgrade your arsenal, deploy soldiers, and survive waves of hostile AI forces led by VAELRA.

The ULTIMATE tower defense onslaught is back. Bigger, deadlier, and more action-packed. Build autonomous defenses, deploy tactical drones, and unleash devastating support abilities in this epic, old-school RTS-inspired sci-fi adventure.

A sci-fi low-poly tower defense game. Design your defense against waves of aliens using a wide arsenal of different towers.

Fight for control of a frontier world. Gather resources, build your base, and command your forces in battle. Survive long enough to unleash your ultimate weapon - THE EPIC.

Build towers and learn abilities to defend against swarms of hundreds of on-screen hostile alien creatures. Choose between sets of randomized upgrades that both upgrade you and the alien swarm. From enormous explosions to far-reaching flamethrowers, no two games are the same.

You are the last survivor. Capture towers, command a squad of unique generals, and battle through 40 missions across 10 distinct worlds as you fight to reclaim a universe that has fallen to the enemy.

Fight battles through human history, defeat your enemies and save humanities future! The Unwanted War lets you follow history itself and take influence on humanities ultimate fate. Are you going to use your knowledge and power for good or will you bring doom over the human race?

Engineered to Purpose is a new tower defence game where you custom-design towers to defend your base, with millions of builds to explore and refine. Set in the far future, E2P's story of posthumanism, family, and change will open new worlds to explore and survive.