Top similar games like AntiBacteria:

Disfigure is a top-down shooter rogue-lite in which you fight countless grotesque creatures shrouded in darkness. Choose from a variety of upgrades to create unique builds each run and survive.

Nebula Cleanup Crew is a short top down action roguelite shooter with a focus on hot and cold weaponry. Rescue your crew members as you blast enemies and bosses away with super heated and chilled weapons — freeze foes, overheat them and unleash powerful supertemp special attacks!

Star of Providence is a top down action shooter with procedurally generated elements. Explore a large, abandoned facility in search of incredible power, fighting dangerous foes and gaining new weapons and upgrades as you progress.

Disfigure is a grim-dark action rogue-like where you battle relentless hordes of monsters lurking in the shadows. Unlock powerful weapons, craft god-like builds with hundreds of upgrades, slay colossal bosses, and push your limits in intense 20–30 minute survival runs!

Psycho Ripper is a top down action shooter with modified conditional formations. Explore a randomization of challenges as you blast through a sentient crystal mine, confronting progressively baneful threats and equip unusual armaments, as you speculate further through a grand and unknown chaos.

A roguelike with unique curses, 60+ cards, incredible shots and power-ups. No two attempts are ever the same.

Locus Protocol is an incremental rogue-lite retro styled twin stick shooter with heavy sci-fi and horror themes. Protect the core from waves of incoming enemies.

Blast your way through the endless swarm of enemies and live for as long as possible in this fast-paced, top-down shooter. Upgrade your tank, collect power-ups, and activate abilities to help you survive on a variety of maps in various game modes. How long will you last before meeting your demise?

One input. Two arenas. One gun. Your clones move in lockstep across a split screen, and only the one holding the gun can shoot. Throw it across the divider to keep the swarm off you. Die, upgrade in the Lab, go further.

A retro arcade style Top down shooting game. Shooting them with a machine gun, blasting them with missiles, dashing them with a vehicle, whipping them with an energy chain, or burning them with a napalm...No matter how you get it done, “ALIEN BUGS MUST DIE!”

GunDeck[100] is a lightning-fast twin-stick shooter where you’ll build your arsenal from randomly-dealt cards. Weapons fire in a rainbow of elements with unique effects. Dart and dodge to survive the fireworks unleashed against you, and retaliate with your own display! Can YOU survive to wave 100?

Overkill Squad is a ultra high-speed top-down shooter roguelike built around intense 1-minute combat arenas. Choose your fighter, unleash overwhelming firepower, defeat brutal bosses, and collect relics to dominate every run.

In this game, you are the bullet hell. Face off against 100 waves of enemies and bosses by collecting a deck of attack cards that activate in real-time to unleash destruction upon everything in sight. There's an insane amount of customizability leading to an infinitely replayable experience.

Hyperwired is a classic top-down action shooter, where your spaceship has a plug hanging from it. Wire yourself into sockets, gather upgrades, and unlock ships as you explore a procedurally generated galaxy with roguelike elements.

Shoot. Dodge. Climb. Repeat. BLOODCAST is a frenetic fast-paced 2D shooter buried in TV static and carnage

Crush, smash, and eat thousands of enemies showing humanity what the meaning of destruction is! Kaiju Catastrophe is an arcade game with roguelite mechanics. Mutate devastating weapons, unlock permanent evolutions, and wreak havoc with a variety of monsters to tear humanity apart!

Core Breach is a fast-paced, twin-stick arcade shooter in a pixel art style. Play as a Trojan worm virus, outmaneuvering and destroying antivirus enemies. Upgrade your worm with powerful attacks and skills as you fight to breach the CPU core and uncover its secrets

Clean, Quota, Upgrade, Repeat. Super Polished is a Top-down cleaning roguelite where you clean up while the mess is still being made.

Fight off hordes of enemies, slay Bosses, choose from a variety of upgrades and combine your spells to create unique and game-breaking builds In this auto-attacking roguelite.

Dead Oculus is a lethal, fast-paced bullet-hell that fuses arcade and roguelike elements. Brutalise your foes in gauntlets of handcrafted arenas by wielding deadly weapons with cataclysmic augments.

Survive shifting universes where the rules themselves change. Build your arsenal across 15-wave runs, claim the Keys, and face a finale built from the worlds YOU conquered. Adapt or die — the strongest build means nothing in the wrong universe.

Sluggerpunk is a gripping 2D survivors roguelike adventure. As you navigate through a myriad of challenges, hone your skills and strategies to clash with formidable foes lurking in the underground. Build a versatile arsenal of abilities and gear to enhance your chances to survive, but will you?

Temp Zero is a minimalist roguelike which mixes intense action and musical bullet hell. Fight enemies which attack to the beat, choose perks, defeat the final boss, unlock new weapons, spells & soundtracks!

Witchinour is a roguelite twin stick shooter focused on fast, 60fps action and constantly increasing difficulty. You play as an explorer who comes across a dungeon that an apprentice witch named Nour found herself lost in years ago on a full moon...

CRATES N' MOHAWKS is a chaotic arena shooter where every crate swaps your weapon. Grab crates, adapt to constantly changing guns, dodge swarms of enemies, and survive as long as possible while pushing your score higher.

Batter Up is a rogue-lite arena battler with a baseball twist! Kill waves of zombies by swinging your bat and sending your ball flying. Build up insane deck combinations and mow through enemies with synergistic upgrade combinations!

SURVIVE in a transforming arena against ALIEN OGRES in this ROGUELIKE BULLET-HELL 💥 MODIFY your gun, make smart upgrade decisions and master your spaceship's controls to conquer the OGRE CHAMBERS !

Take control of a heavily armed squid and blast through destructible worlds in Freedom Squid Fighter. Soar through the air, tunnel through dirt and rock with powerful weaponry, and outmaneuver enemies across fully destructible landscapes.

DEATHRUN TV is a fast hardcore rogue-lite twin-stick shooter set in the world's biggest and craziest game show. You'll experience real-time blistering speed and bullet-dodging action as you compete for glory...assuming you’re able to survive in this 2D bullet hell where only “likes” really count.

Huedini is a colour-matching action roguelike game. Play as Huedini, a powerful wizard with the ability to change his colour. By matching your colour, to that of the enemies you can absorb their colour essence. By combining these colour essences into the correct combination, you can cast spells.

Nuclear Throne is a post-apocalyptic roguelike-like top-down shooter. Not 'the final hope of humanity' post-apocalyptic, but 'humanity is extinct and mutants and monsters now roam the world' post-apocalyptic. Can you reach the Nuclear Throne?

Void Prison is a fast paced, endless arcade twin stick shooter that puts you inside of an ever shrinking ring. Survive by fighting emerging enemies around you and don't get consumed by the void. Complete achievements to unlock new skins and powerups and get on top of the leaderboards!

Cards and Guns is a top-down arena shooter roguelite, where you’ll have to defeat hordes of creatures. Choose from a variety of cards and upgrades to create unique builds and survive to the end.