Top similar games like DNA Farm:

Explore vast and deep interiors of an underground research center, brimming with creative foes, bosses, NPC's, and more. Craft your equipment from scavenged tech, and uncover Biotec's dark experiments.

Unknown Warrior, pick up your weapons, plant a variety of plants, resist the surging monsters, and protect the Holy Tree!

The definitive version of the smash-hit Metroidvania-style action-platformer, Guacamelee! STCE adds new levels, powers, challenges, and refinements to the sprawling, ridiculous, Mexican-inspired adventure of the original Guacamelee! Gold Edition.

Embark on a short and emotional journey through a cursed cave in this 2D hand-drawn platformer with action and metroidvania elements. Uncover a touching story about regrets and the value of living the moment

Dash, slash, and shoot through handcrafted levels across vibrant worlds in a fast-paced action platformer! Stop the forces of evil from stealing your mysterious lunch and uncover the destiny that awaits you!

Sinner's Tavern is a metroidvania, focused on fast paced combat and interactions with quirky characters. Inspired by the Dante’s Inferno, help Oscar and his grandpa escape while they announce that Satan's tavern... is now open!

Fall of Gorithia: Nym's Fate is a 2D action adventure set in the ancient land of Gorithia. Go from simple thief to magic wielding warrior as you battle your way through the fallen kingdom on your quest to find your lost brother in this sprawling fantasy world.

An epic bite-size action adventure microidvania through a surreal world of mutated animals and environments. Combat mice engineers and religious birds, traverse a strange world and its life-altering climates, and combine steam and spark to fix the world, all in a classic, hand-drawn 2D style.

Embark on a gripping journey through Neon Moon, a dynamic Metroidvania where you confront ancient adversaries, unleash extraordinary abilities, and unearth potent relics, driven by the sole desire to conquer the enigmatic Dark Night haunting Nightlight.

Spit your scales. Build your path. Master every challenge. Pogona is a challenging hand-drawn 2D metroidvania starring a tiny lizard who turns her own scales into platforms and weapons. Master a rewarding movement system, unlock ancient powers, and conquer a world full of secrets.

2d hand drawn female protagonist action-adventure/soulslike.

A 2D stealth Metroidvania with parkour platforming. Explore the majestic palace and ancient prisons of a kingdom under siege. Don the mantle of the legendary Sandfox as you venture into the ruins below, and discover the true threat from a sand-borne evil.

Elysian Echoes is a traditional, hand crafted souls-like metroidvania with a twist. Take possession of your fallen enemies bodies and unveil your cosmic destiny as you untangle Gaia's turmoil. Adapt to the varied and difficult encounters; learn and use your enemies' moves against them or die trying.

A dark Metroidvania where memory and madness intertwine. Explore surreal biomes, face grotesque bosses born of trauma, and recover fragments of a forgotten identity in a world that twists with your sanity.

SpellTome is a story driven fantasy adventure 2D platformer. Hurl balls of magic, dash across levels, and jump over obstacles while trying to get the fabled SpellTome.

Tunnels is a single-player mining metroidvania adventure. Delve the alien depths, upgrade your tank, master deep itemization, and uncover the mysteries below.

Join Zeleny on his adventure through the Dardaglia region and unveil all the mysteries hidden within it. Explore maze-like paths and test yourself as you face numerous dangers while unlocking new skills.

Switch, adapt, and evolve in Phaze Shift, an action-platformer Metroidvania. Swap between two characters, fuse upgrades to forge new abilities, battle mechanized bosses, and explore a sleeping digital world in a hand-drawn diorama-style 2D adventure.

Clarity is a 2D side scrolling platforming adventure. Choose to face seven demons and acquire their demon sword and demon magic. Each sword and spell, has an elemental strength against a corresponding demon.

Fast-paced, action packed metroidvania-styled goodness that does not hold back! Explore a massive world as you battle against hoards of crawling, rolling and flying insects.

One misty moonlit night, Count Dracula is attacked by an orange object from the sky. He finds himself awaking on a mysterious island with a pumpkin stuck to his head. With the new power of the pumpkin that protects Dracula from sunlight, he must find his way off the island and back to his Castle.

A dying planet in energy chaos, dangerous districts and challenging combats. Your only chance to escape the planet is through inconsistent portal! Gain energy crystals by slaying enemies. Improve your abilities and acquire drones. Complete your escape quest in this challenging rouge-lite gameplay.

This adventure pits a lone explorer against the dangers of a strange underground world while blending classic 2D platforming with heart-pounding twin-stick shooting. Embrace the fun and excitement as you jump, shoot, and dash your way through to restore the severed link to the surface

An immersive journey deep within the decaying remains of a forgotten behemoth; blending combat, puzzles and movement trials as you discover new ways to traverse. Smash through the belly of the beast in this hand-drawn 2D platformer, challenging all which emerges from it’s decay.

TIES: Soul Link is an emotional and brutal 2D metroidvania that combines action RPG with adventure platforming. Explore a decaying world in the year 2097, uncover its secrets, and face savage, bloody battles that will test your endurance and your deepest fears.

Flow gracefully through a colorful, hand-drawn 2.5D action platformer inspired by Japanese folklore. Engage in acrobatic aerial combat, unlock powerful mystical abilities, and explore an interconnected world of myth as you seek to unravel the mysteries of your origin.

Seek the path to your freedom! Join to 84831 (Babel) on his journey to change the way his world is ruled. Dystobel is a metroidvania based on the change of powers with which you can dodge and nullify attacks, with multiple objects to discover and equip.

RuneShroom is a 2D action platformer where you play as Mushu. You must journey forth! Armed with an array of hand animated spell to drive the snails who have decimated the your people's lands, and who now endanger the very diety who gave you life.

In this 2D action platformer, you'll play as a humanoid reptile and save the planet and your people from an evil corporation! Reach the control center and activate the self-destruct mechanism! It won't be easy, as there are plenty of traps, obstacles, and heavily armed guards in your way!

Boost and grapple around a cyberpunk cityscape in Kinetic Breakthrough, a high-speed metroidvania. Use your momentum to break through windows, destroy drones, and confront the artificial intelligence that keeps the city under its control.

Destinesia is a sci-fi metroidvania which you are looking for a new home for humanity. Parkour your way through most dangerous jungles and explore the ancient dungeons. Upgrade your suit with the remains of your ancestors. Reveal the oldest secrets of Homo Sapiens.