Top similar games like Pathogen:

Take control of limitless power in Prehistoric Kingdom to build, manage and grow the ultimate zoo for extinct animals.

A management sim where you run your own food shops, serving hungry locals while keeping a close eye on your resources. Grow or buy fresh ingredients locally. The competition is fierce and sabotage is always on the menu. Defend your business, and rise to become the food lord!

Icetwine is an ice-age city builder where you drag and combine raw materials to craft tools, machines, and structures! Unite wood, stone, and iron to build cozy huts, thriving farms, and even tame dodos and mammoths as you forge a flourishing prehistoric village!

Bleak Frontier is a strategy / city builder game set in a frozen wasteland in the far future, 4087 AD. As the chosen leader of the first permanent settlement in almost a century, you must guide the last survivors of the human race towards an uncertain future. Welcome to the Bleak Frontier.

Take control of the most fearsome weapon known to mankind: the key interest rate. As head of the central bank, you wield the power to make (or break) nations. Raise it, and watch markets crumble and riots erupt. Lower it, and brace yourself for an economy so hot it could melt steel.

Extinction Day is a doomsday simulator where you wipe out humanity using disasters, diseases, wars, and other catastrophic events. Spread chaos worldwide, combine catastrophes for maximum destruction, and crush humanity's efforts to survive in this game of world-ending mayhem.

Manage your own brasserie in Paris and turn it into the place to be! Create menus, serve customers, and master every detail to grow your restaurant. Manage supplies, ensure top-notch service, and make your mark on the city of lights. Will you become the next Parisian brasserie institution?

Fight against huge hordes of geometric amalgamations with BOTH towers and allied defenders to stop them from breaking your CORE! Travel to barren deserts, hostile wastelands in this fast-paced tower-defence game.

Revolutionary grand-scale RTS game played on maps of any 3D shape. It emphasizes base building and logistics, careful planning, and minimizes micro-management of units.

Develop your computer empire, control costs, and increase profits. Decide whether to develop hardware in-house or purchase it, and whether to prioritize cost-effectiveness or pursue higher profits. The choices are all up to you.

Do you like Tower Defense games with Strategy elements? Well, look no further! We've got exactly what you're looking for! Get ready to defend your settlement from enemies using a huge arsenal of towers!

Recovery Syndicate is a prequel to Abeyance, in which you are the leader of one of the factions trying to reconstruct the economy of the galaxy. You must build and manage your colony's resources carefully, while watching out for rival factions who are also vying for supremacy.

Polyion is a world management game where you can create and manage your own world and its resources. Place buildings, manage your resources, keep your population happy and create a thriving world.

Build infrastructure to connect the expanding world to the internet! Having a working strategy and great management is key to winning your competition in this capitalist environment.

Pillazon is an MMO virtual business simulation game where you work as the CEO of a new company. Your mission is to create your own website and build the world's extensive drug empire!

In this real time strategy city builder game you will help humanity in reaching beyond earth by establishing a permanent and thriving settlement in the asteroid belt. Settling in space comes with enormous challenges and dangers, which you will have to guide your people through

Build mechas, form mecha teams, and command them to fight.

Build an intricate prison, hire the best staff, and pamper your prisoners to create the perfect rehabilitation facility in Prison Tycoon: Under New Management

A citybuilder inspired by classics such as Ceasar III, Anno, Pharaoh and others which takes place the bottom of the ocean. The surface has become uninhabitable and raybomb radiation has turned many into mutants. It is your job to set up your underwater empire and guide new humanity to greatness!

The epic story of evolution, technology, humanity, and dinosaurs is yours to tap.

Rule the state in this political strategy simulatior by interacting with characters and with the map. Each of your decisions will necessarily entail a result. The game raises topical problems of the modern world, politics and humanity as a whole.

Cities Virtual Reality is a VR city builder. You have a wide range of tools that you can use to build up your city! Play in a relaxing sandbox or play the campaign for a more intense experience.