Top similar games like Pathogen:

Take on the role of park manager and design the ultimate zoo for nature's greatest creations.

A management sim where you run your own food shops, serving hungry locals while keeping a close eye on your resources. Grow or buy fresh ingredients locally. The competition is fierce and sabotage is always on the menu. Defend your business, and rise to become the food lord!

A vertical kingdom in the sky! Plan your ascent from the harsh Sand Zone, rising layer by layer as you and your Towertizens stand together against looming disasters. Build trade ports and vertical supply networks. Perform Rituals to shape miracles, and witness the prosperity of this rising nation.

Bleak Frontier is a strategy / city builder game set in a frozen wasteland in the far future, 4087 AD. As the chosen leader of the first permanent settlement in almost a century, you must guide the last survivors of the human race towards an uncertain future. Welcome to the Bleak Frontier.

Fight against huge hordes of geometric amalgamations with BOTH towers and allied defenders to stop them from breaking your CORE! Travel to barren deserts, hostile wastelands in this fast-paced tower-defence game.

Revolutionary grand-scale RTS game played on maps of any 3D shape. It emphasizes base building and logistics, careful planning, and minimizes micro-management of units.

Do you like Tower Defense games with Strategy elements? Well, look no further! We've got exactly what you're looking for! Get ready to defend your settlement from enemies using a huge arsenal of towers!

Develop your computer empire, control costs, and increase profits. Decide whether to develop hardware in-house or purchase it, and whether to prioritize cost-effectiveness or pursue higher profits. The choices are all up to you.

Keep it cool or raise the heat in this first-person, online, control point, party game with up to 8 players. The hot-tempered Gelava (Jellies) will crank up the reactor’s heat, while the stone-cold Koizo (Fish) scramble to cool it down. Which team are you picking?

Recovery Syndicate is a prequel to Abeyance, in which you are the leader of one of the factions trying to reconstruct the economy of the galaxy. You must build and manage your colony's resources carefully, while watching out for rival factions who are also vying for supremacy.

2D automation game set in a time loop. Only time anchored factories and knowledge can be carried through multiple loops, until a way to escape time is discovered. Manage factories, production, research and bonuses to reach the end. What will you carry an what will you leave to the mercy of time?

Polyion is a world management game where you can create and manage your own world and its resources. Place buildings, manage your resources, keep your population happy and create a thriving world.

City Builder Pro lets you unleash your inner ruler—design your dream base, prepare for epic battles, and feel the thrill of watching your city grow and dominate. Build smart, strike hard, and rise to power!

Build infrastructure to connect the expanding world to the internet! Having a working strategy and great management is key to winning your competition in this capitalist environment.

Pillazon is an MMO virtual business simulation game where you work as the CEO of a new company. Your mission is to create your own website and build the world's extensive drug empire!

In this real time strategy city builder game you will help humanity in reaching beyond earth by establishing a permanent and thriving settlement in the asteroid belt. Settling in space comes with enormous challenges and dangers, which you will have to guide your people through

Build mechas, form mecha teams, and command them to fight.

Take on the challenge of managing these Little Renters and their needs. Keep them happy with the right decoration and set your rent prices to maximize profits! Stay alert as Thieves, Squatters, Fires, Sick Renters and Broken Decorations can cause you to Fail!

Build an intricate prison, hire the best staff, and pamper your prisoners to create the perfect rehabilitation facility in Prison Tycoon: Under New Management

An atmospheric city-builder inspired by classics like Caesar III, Anno, and Pharaoh—set on the ocean floor. Build, manage, and expand your underwater colony as humanity flees a dying world. Balance resources, population, and survival in this deep colony sim across a structured campaign.

The epic story of evolution, technology, humanity, and dinosaurs is yours to tap.

Cities Virtual Reality is a VR city builder. You have a wide range of tools that you can use to build up your city! Play in a relaxing sandbox or play the campaign for a more intense experience.

Rule the state in this political strategy simulatior by interacting with characters and with the map. Each of your decisions will necessarily entail a result. The game raises topical problems of the modern world, politics and humanity as a whole.

Double Envelopment is a 3D sandbox low poly RTS battle simulator featuring semi-realistic building destruction, a full-range map editor, and ability to launch multi-front offensives against cities using infantry, paratroopers, tanks, and more.

Estate Empire is a multiplayer strategic game inspired by classic board games. Compete against your friends and develop your own strategy to win, and try to dismantle your friend's empire. Invest in the same street as your friends, use your cards or become the mayor to create new laws against them.

Craft bio-weapons, master lethal science, and unleash global annihilation. Experiment. Fail. Adapt. Evolve. Repeat—until humankind falls.

Become the billionaire you always mocked! Collect humans like trading cards, exploit their productivity, and compete in The Excess Index - where morally bankrupt capitalism is the only way to win. Own everything. Question nothing.

Looking for a fun and addictive farming simulation game? Look no further than Farm Day 2023! Develop your farming capabilities, grow crops, and build your own town. With beautiful graphics and a relaxed gameplay style, it's perfect for players of all ages. Start your farming adventure today!

Experience the mysterious and mystical by taking on a journey with Mims in this strategic god-like game. Create structures, plant vegetation, breed animals, take care of your minions, use divine PSI powers, triumph in face of natural disasters, fight monsters, predict the future, and so much more...

Welcome to Mall Manager, where you can build and manage your personalized mall. Choose your manager, design from scratch, and expand across unique worlds. A friendly indie management sim.

Space 4X game with the ability to build factories, extract resources, with characters, internal and external markets ... Take part in the discussion of the game, share your vision)

Manage your own brasserie in Paris and turn it into the place to be! Create menus, serve customers, and master every detail to grow your restaurant. Manage supplies, ensure top-notch service, and make your mark on the city of lights. Will you become the next Parisian brasserie institution?

Dive into a world of creation and discovery, where each element combines to form new ones. Experiment freely in this interactive sandbox. But be careful: every combination has its consequences..

Creo God Simulator is a game of city building, resource management, survival, and a ton of villager smiting. As the divinely chosen Creostrider, it's your job to build a society bit by bit, while convincing your new population to believe in you as their one true god.