Top similar games like Pathogen:

Take control of limitless power in Prehistoric Kingdom to build, manage and grow the ultimate zoo for extinct animals.

A management sim where you run your own food shops, serving hungry locals while keeping a close eye on your resources. Grow or buy fresh ingredients locally. The competition is fierce and sabotage is always on the menu. Defend your business, and rise to become the food lord!

Icetwine is an ice-age city builder where you drag and combine raw materials to craft tools, machines, and structures! Unite wood, stone, and iron to build cozy huts, thriving farms, and even tame dodos and mammoths as you forge a flourishing prehistoric village!

Bleak Frontier is a strategy / city builder game set in a frozen wasteland in the far future, 4087 AD. As the chosen leader of the first permanent settlement in almost a century, you must guide the last survivors of the human race towards an uncertain future. Welcome to the Bleak Frontier.

Take control of the most fearsome weapon known to mankind: the key interest rate. As head of the central bank, you wield the power to make (or break) nations. Raise it, and watch markets crumble and riots erupt. Lower it, and brace yourself for an economy so hot it could melt steel.

Extinction Day is a doomsday simulator where you wipe out humanity using disasters, diseases, wars, and other catastrophic events. Spread chaos worldwide, combine catastrophes for maximum destruction, and crush humanity's efforts to survive in this game of world-ending mayhem.

Manage your own brasserie in Paris and turn it into the place to be! Create menus, serve customers, and master every detail to grow your restaurant. Manage supplies, ensure top-notch service, and make your mark on the city of lights. Will you become the next Parisian brasserie institution?

Fight against huge hordes of geometric amalgamations with BOTH towers and allied defenders to stop them from breaking your CORE! Travel to barren deserts, hostile wastelands in this fast-paced tower-defence game.

Do you like Tower Defense games with Strategy elements? Well, look no further! We've got exactly what you're looking for! Get ready to defend your settlement from enemies using a huge arsenal of towers!

Recovery Syndicate is a prequel to Abeyance, in which you are the leader of one of the factions trying to reconstruct the economy of the galaxy. You must build and manage your colony's resources carefully, while watching out for rival factions who are also vying for supremacy.

Polyion is a world management game where you can create and manage your own world and its resources. Place buildings, manage your resources, keep your population happy and create a thriving world.

Build infrastructure to connect the expanding world to the internet! Having a working strategy and great management is key to winning your competition in this capitalist environment.

Pillazon is an MMO virtual business simulation game where you work as the CEO of a new company. Your mission is to create your own website and build the world's extensive drug empire!

In this real time strategy city builder game you will help humanity in reaching beyond earth by establishing a permanent and thriving settlement in the asteroid belt. Settling in space comes with enormous challenges and dangers, which you will have to guide your people through

Build mechas, form mecha teams, and command them to fight.

Build an intricate prison, hire the best staff, and pamper your prisoners to create the perfect rehabilitation facility in Prison Tycoon: Under New Management

A citybuilder inspired by classics such as Ceasar III, Anno, Pharaoh and others which takes place the bottom of the ocean. The surface has become uninhabitable and raybomb radiation has turned many into mutants. It is your job to set up your underwater empire and guide new humanity to greatness!

The epic story of evolution, technology, humanity, and dinosaurs is yours to tap.

Rule the state in this political strategy simulatior by interacting with characters and with the map. Each of your decisions will necessarily entail a result. The game raises topical problems of the modern world, politics and humanity as a whole.

Cities Virtual Reality is a VR city builder. You have a wide range of tools that you can use to build up your city! Play in a relaxing sandbox or play the campaign for a more intense experience.

A classic RTS in VR, where you command a high-tech force against a battle-hardened enemy. Tactically stack your structures in the right order to switch between firepower and resource gathering. Accurately throw reinforcements towards a combat zone. The war room of the future awaits you!

Estate Empire is a multiplayer strategic game inspired by classic board games. Compete against your friends and develop your own strategy to win, and try to dismantle your friend's empire. Invest in the same street as your friends, use your cards or become the mayor to create new laws against them.

Looking for a fun and addictive farming simulation game? Look no further than Farm Day 2023! Develop your farming capabilities, grow crops, and build your own town. With beautiful graphics and a relaxed gameplay style, it's perfect for players of all ages. Start your farming adventure today!

Welcome to Mall Manager, where you can build and manage your personalized mall. Choose your manager, design from scratch, and expand across unique worlds. A friendly indie management sim.

The Settlers®: New Allies is a strategy game with an in-depth build-up experience and real-time strategic battles.

Space 4X game with the ability to build factories, extract resources, with characters, internal and external markets ... Take part in the discussion of the game, share your vision)

Welcome to Explorers of Esmar! Build your settlement, master complex production chains. Claim the riches to explore and conquer the new island continent of Esmar!

Subzero Tides is a sci-fi colony builder set on Europa moon. Build a self-sustaining colony, harness geothermal vents for power and manage colonists. Experience a compelling blend of exploration, survival, and strategic decision-making.

Dive into a world of creation and discovery, where each element combines to form new ones. Experiment freely in this interactive sandbox. But be careful: every combination has its consequences..

Creo God Simulator is a game of city building, resource management, survival, and a ton of villager smiting. As the divinely chosen Creostrider, it's your job to build a society bit by bit, while convincing your new population to believe in you as their one true god.

The technologically advanced humanity starts looking for other planets to conquer. Now that the Earth is depleted of its resources, we're looking for them elsewhere. The Universe is open for us now - and it cannot hide any secrets. So how will you conquer it?

Launch a rocket. Extend the Antenna. Set your internet service price and start making money. Oh and shoot down asteroids if they threaten your satellites.

Purrfect Galaxies is a text-based strategy game. As the ruler of the planet Cataris, hungry cats await your decisions. Will you let your meowpurrlation bask in catnip bliss, or will they unsheathe their claws and seal your doom?

The First Explorers® is a Settlers-like game, that offers the perfect mix of organic city-building and RTS in a bustling world. Set in the time of antiquity in Europe, you will play as the Romans, Carthaginians or Gauls. Are you ready to raise an army backed by a thriving economy?