Top similar games like Isolate ME!:

A New Kind of Action Game Where You “Get Weaker” the More You Play. Words wage war. Every enemy, every weapon, and you yourself — everything is made of words. Cut through hordes of living characters, seize skills, and evolve from Human to God.

Deadly Racing Duel - in the role of a racer who conquers circuit auto racing, you accept challenge after challenge in order to prove how good a racer you are.

Delve into the mystical depths of the Emerald Forest in this captivating roguelike. You play as a courageous fox, wielder of powerful spells, the last bulwark against the growing corruption.

The Apocalypse Begins! Select a supernatural being and plunge the world into chaos. Defeat countless enemies, turn them into minions, destroy everything in your path and upgrade your creature with many different skills. Ascend to become ultimate Apocalypse Lord!

Can you survive against crazy cultists and be the last cult standing?

A neon horde-survival roguelite where your cursor is the only weapon. Guard the core, sweep through endless swarms with osu!-style precision, evolve a build from loot-tier upgrades, and outlast 10 nightmare bosses. Then chase a cheat-proof global leaderboard.

Push blocks. Crush enemies. Survive the void. CARGO CRUSH ZERO is a roguelite grid-action game set aboard a derelict space station. Outmaneuver alien creatures by sliding cargo blocks across a zero-gravity field — one wrong move and you're cornered.

Get ready for the ultimate space challenge! In this top-down action roguelite you’ll pilot your ship through a low-gravity environment, dodging obstacles and fighting enemies along the way. But be careful, one wrong move could mean the end of your journey. Are you ready to take on the challenge?

Push and kill waves of enemies on the ancient pillar of sacrifice to become the only one left standing. Wishlist to follow updates and get notified at launch

A Bullet-Heaven roguelike in the Approaching Infinity universe with both spaceship and away team missions. The exit of the galaxy's dominant races left a power vacuum that everyone wants to fill. Survive, pick a side, or kill'em all. No time to think when the horde's advancing.

A neon pixel rhythm-arcade roguelite. Charge and launch orbit blades, bounce through enemy waves, build synergies, trigger FEVER bursts, master clean rebounds, survive evolving boss patterns, and chase high-score survival runs on Steam Leaderboards.

In this arcade roguelite, your car runs on blood and the zombies have plenty. Smash through the horde, drift to drain every last drop, and spin the roulette for brutal upgrades while you fight to survive the endless horde.

Crush, smash, and eat thousands of enemies showing humanity what the meaning of destruction is! Kaiju Catastrophe is an arcade game with roguelite mechanics. Mutate devastating weapons, unlock permanent evolutions, and wreak havoc with a variety of monsters to tear humanity apart!

Go on a campaign to dethrone the kaiser! Build an army, strengthen yourself with powerful artefacts and defeat the forces he sends to stop you. Kaiser is a casual roguelike game where you fight thousands of enemies in an attempt to become the new kaiser.

Pilot the last vessel of a fallen civilization into the vast expanse of space. Collect resources and search for a new world to call home in this minimalist space exploration and survival game.

Mystic Labyrinth is a top-down 2D twin stick shooter rogue-lite game. Choose from multiple starting classes and use swords, spears, axes and magic to conquer the many themed floors of the labyrinth.

Slimenator is a roguelite where you battle endless waves of slimes trying to overtake the world! Choose and customize up to six powerful skills, along with rare relics and accessories, as you craft the ultimate build to survive the slime apocalypse and outlast the ever-growing swarm!

Retro rally racing with a simulation twist

CHAT CHAMPIONS is an interactive pixel battle simulator built for live streaming on Twitch.

Blast through hostile sectors, collect valuable data, and combine permanent upgrades into devastating builds. Master guns, blades, bombs, companions, and powerful abilities as escalating threats test your reflexes. Every run brings you closer to conquering Sector 50, and crushing the core.

Dungeon Core is a roguelite top-down shooter where you get to explore the sewers and beyond to ultimately reach an old underground research facility. Old nuclear waste has caused dangerous mutations in creatures due to a failed experiment. You set out to destroy the abandoned nuclear core.

Tribe of Werewolves is a rogue-lite survival game where you fight against hordes of creatures using various weapons and spells. Survive as a bloodthirsty werewolf and save all the tribe members!

Assume control of a courageous adventurer and blaze through monster infested mazes. Dance with death as you balance fighting with scavenging for loot and power in this classic-arcade inspired roguelike.

SMaC! is an anomaly-spotting game where you work as a shotgun-wielding maid. Identify fake customers by their behavior and blow them away, while keeping the real ones happy with their orders.

Mine, fight monsters, upgrade your gear, obtain rare items, unlock new powers and mine some more in the massive follow-up to the popular title "Haste-Miner 2". Eternamine offers a casual yet engaging gameplay experience, expand your mining empire and discover the secrets that lie beneath the earth.

Srogue is a snake roguelite where you play as a snake and defeat enemies in order to feast and grow. Unlock new ways to play by gaining experience and choosing items to alter your snake. The goal is to survive as long as possible.

Be the defender of innocence, the last remaining virtue in this land, and prevail against the evildoers! Sentinel of Innocence is a survival game with tower defense and rogue-lite elements.