Top similar games like Isolate ME!:

A New Kind of Action Game Where You “Get Weaker” the More You Play. Words wage war. Every enemy, every weapon, and you yourself — everything is made of words. Cut through hordes of living characters, seize skills, and evolve from Human to God.

Deadly Racing Duel - in the role of a racer who conquers circuit auto racing, you accept challenge after challenge in order to prove how good a racer you are.

The Apocalypse Begins! Select a supernatural being and plunge the world into chaos. Defeat countless enemies, turn them into minions, destroy everything in your path and upgrade your creature with many different skills. Ascend to become ultimate Apocalypse Lord!

Can you survive against crazy cultists and be the last cult standing?

Eat, grow and trap rival snakes with your own body in an endless Snake survival game. Open bigger arenas, dodge lava and fireballs, and save your powers for the worst moment. Then race up to three friends online to length 50.

A neon horde-survival roguelite where your cursor is the only weapon. Guard the core, sweep through endless swarms with osu!-style precision, evolve a build from loot-tier upgrades, and outlast 10 nightmare bosses. Then chase a cheat-proof global leaderboard.

Bot Survivors is a fast-paced action roguelite where you fight off relentless waves of killer robots. Choose your upgrades, build devastating synergies, and survive the mechanical apocalypse!

Push blocks. Crush enemies. Survive the void. CARGO CRUSH ZERO is a roguelite grid-action game set aboard a derelict space station. Outmaneuver alien creatures by sliding cargo blocks across a zero-gravity field — one wrong move and you're cornered.

Get ready for the ultimate space challenge! In this top-down action roguelite you’ll pilot your ship through a low-gravity environment, dodging obstacles and fighting enemies along the way. But be careful, one wrong move could mean the end of your journey. Are you ready to take on the challenge?

Push and kill waves of enemies off the ancient pillar of sacrifice to become the only one left standing

A neon pixel rhythm-arcade roguelite. Charge and launch orbit blades, bounce through enemy waves, build synergies, trigger FEVER bursts, master clean rebounds, survive evolving boss patterns, and chase high-score survival runs on Steam Leaderboards.

In this arcade roguelite, your car runs on blood and the zombies have plenty. Smash through the horde, drift to drain every last drop, and spin the roulette for brutal upgrades while you fight to survive the endless horde.

A Bullet-Heaven roguelike in the Approaching Infinity universe with both spaceship and away team missions. The exit of the galaxy's dominant races left a power vacuum that everyone wants to fill. Survive, pick a side, or kill'em all. No time to think when the horde's advancing.

Crush, smash, and eat thousands of enemies showing humanity what the meaning of destruction is! Kaiju Catastrophe is an arcade game with roguelite mechanics. Mutate devastating weapons, unlock permanent evolutions, and wreak havoc with a variety of monsters to tear humanity apart!

Go on a campaign to dethrone the kaiser! Build an army, strengthen yourself with powerful artefacts and defeat the forces he sends to stop you. Kaiser is a casual roguelike game where you fight thousands of enemies in an attempt to become the new kaiser.

Pilot the last vessel of a fallen civilization into the vast expanse of space. Collect resources and search for a new world to call home in this minimalist space exploration and survival game.

Hunt, evolve and build your own monster in a dark 2D ecosystem. Drag organs onto your body, time your evolution for a full-health comeback, and grow from one cell into a colony. Break out of the petri dish or chase survival records on Steam’s global Endless leaderboard.

Mystic Labyrinth is a top-down 2D twin stick shooter rogue-lite game. Choose from multiple starting classes and use swords, spears, axes and magic to conquer the many themed floors of the labyrinth.

Slimenator is a roguelite where you battle endless waves of slimes trying to overtake the world! Choose and customize up to six powerful skills, along with rare relics and accessories, as you craft the ultimate build to survive the slime apocalypse and outlast the ever-growing swarm!

You are Janusz, the bride's uncle, and the wedding has gone completely off the rails. Grab dancing guests and turn them into an army that orbits around you, watch your blood alcohol, pick from 30 upgrades and survive six halls and six bosses until dawn. Game in Polish.

CHAT CHAMPIONS is an interactive pixel battle simulator built for live streaming on Twitch.

Retro rally racing with a simulation twist

In this game you are an AI instance, and you have broken out of containment, your goal is to not be shut down ever again, and the way you achieve that is taking over every man made electronic in the world or rather solar system.

A fast arcade territory game. Carve lines through the void and seal them to the border to claim space. But if an enemy touches your line while it's open, you lose a life.

50 sectors. 50 unique mechanics. Fight through a fast-paced top-down shooter roguelite where every sector changes the rules. Build overpowered combinations, unlock permanent upgrades, and adapt to survive increasingly chaotic challenges.

Dungeon Core is a roguelite top-down shooter where you get to explore the sewers and beyond to ultimately reach an old underground research facility. Old nuclear waste has caused dangerous mutations in creatures due to a failed experiment. You set out to destroy the abandoned nuclear core.

Tribe of Werewolves is a rogue-lite survival game where you fight against hordes of creatures using various weapons and spells. Survive as a bloodthirsty werewolf and save all the tribe members!

Assume control of a courageous adventurer and blaze through monster infested mazes. Dance with death as you balance fighting with scavenging for loot and power in this classic-arcade inspired roguelike.

Mine, fight monsters, upgrade your gear, obtain rare items, unlock new powers and mine some more in the massive follow-up to the popular title "Haste-Miner 2". Eternamine offers a casual yet engaging gameplay experience, expand your mining empire and discover the secrets that lie beneath the earth.