Top similar games like Mutagenesis:

Survive and thrive in a post-apocalyptic future — resources are scarce, but opportunity calls! Build the ultimate disaster proof colony, protect your colonists, and restore civilization to a devastated world.

Endzone is a post-apocalyptic survival city builder, where you start a new civilization with a group of people after an ecological disaster. Build them a new home and ensure their survival in a shattered world, threatened by constant radiation, toxic rain, sandstorms and droughts.

Build, scavenge, craft, and perform occult rituals to survive in a demon-infested, post-apocalyptic colony simulation. Will you survive Judgment day?

ATC is a base building game set in a post-apocalyptic world featuring urban environments. Build a base across several layers with dozens of survivors. Fight other factions for the control of the remaining production centers and explore the world to find long forgotten resources and technologies.

LiF:Forest Village is a city builder with survival aspects in a realistic harsh medieval world. Shape, build and expand your settlement, grow various food to prevent your villagers from avitaminosis and starvation. Possess them for additional micromanagement or simply to wander around.

New Cycle is a city building game with focus on survival. After an apocalyptic series of solar flares, human society has been thrown into disarray. Establish a settlement and develop it all the way from humble beginnings to industrial metropolis.

There will be challenges to overcome. Execute your strategy and improve your colony’s chances of survival while unlocking the mysteries of this alien world. Are you ready? Mars is waiting for you.

Neo Citizen - Prologue - A management and strategic game in which you will have to manage your resources to the best of your ability. Make connections with the inhabitants, improve the infrastructure and defend yourself from the dangers of a hostile and corrupt world.

Commander, lead your army, build the strongest weapons, conquer the harsh weather and enemies, and build a new Eden on the sea!!!!

Gnomoria is a sandbox village management game where you help lead a small group of gnomes, who have set out on their own, to thrive into a bustling kingdom! Anything you see can be broken down and rebuilt elsewhere.

Crowded Blue Dot is a game about producing various items to make people happy and growing a city from a small village to a metropolis.

The world after a nuclear war. Manage the settlement, learn technology, make decisions, produce weapons, ammunition, organize defense, raid for supplies on other areas, do not let residents die, survive the nuclear winter.

Frostpunk is the first society survival game. As the ruler of the last city on Earth, it is your duty to manage both its citizens and infrastructure. What decisions will you make to ensure your society's survival? What will you do when pushed to breaking point? Who will you become in the process?

Recovery Syndicate is a prequel to Abeyance, in which you are the leader of one of the factions trying to reconstruct the economy of the galaxy. You must build and manage your colony's resources carefully, while watching out for rival factions who are also vying for supremacy.

Set in a gritty, fictional 1960s universe, it’s a colony sim / base-building / grand strategy hybrid where you rebuild a war-ravaged region, fortify your defenses, and control key trade routes that every convoy depends on.

A sci-fi colony sim driven by an intelligent AI storyteller. Generates stories by simulating psychology, ecology, gunplay, melee combat, climate, biomes, diplomacy, interpersonal relationships, art, medicine, trade, and more.

Automate a lunar base as you become the savior of humanity exploring the future on the moon. Mine, craft, research, and trade resources with Earth in this gripping narrative basebuilder.

Building and managing a late medieval city is a series of challenges. Build wells to provide drinking water, markets to provide bread and food, and theaters to collect performance tax. Stage mode continues an interesting story and journey, random map mode fills each game with a new experience.

Clanfolk is a colony sim set in the Scottish Highlands. Harness your environment to survive - fish, gather, hunt, and farm as you prepare for the winter. Build an inn, trade with other clans, have children and marry them off - live life and prosper across the generations.

Guide a group of space settlers trying to establish a base on a remote planet. Grow food, collect energy, mine resources, survive disasters and build a self-sufficient colony in a harsh and unforgiving environment.

As the Queen's latest governor, build a colonial empire in Her name. Claim islands, collect their natural resources, build production chains, and turn a derelict outpost into a rebellious, bustling metropolis at the heart of a New World commercial empire!

Avian Colony is a survival simulation game that places you in the role of the ruler of a floating colony in a harsh sky world. Your main goal is to ensure the survival and prosperity of your colony by managing resources, planning strategically, and defending against threats.

It is a strategy and survival game set in a world turned into a desert by nuclear wars. Gather scarce resources, manage your team, build your town, and engage in strategic battles. Do you have what it takes to survive?

Endzone 2 is a post-apocalyptic survival colony builder, where you embark to secure humanity's survival after a cataclysmic disaster. Discover and repopulate the last habitable grounds, while the survival of your people hinges on your wits, foresight, and resilience in a harsh and unforgiving world.