Top similar games like Defense Protocol:

Qubicks is where tower defense meets roguelike as you venture across procedurally generated levels where you strategically position towers, balancing immediate survival with long-term growth. Upgrade your towers and heroes to adapt to difficult waves and ensure victory against alien inhabitants.

A Roguelike Tower Defense game set on a user controlled procedurally generated island. Select unique cards and relics that enhance your towers abilities, crafting powerful builds to defend against the growing hordes of enemies.

Cards of Prophecy combines Tower Defense, Deckbuilding, and Roguelike elements, with huge inspiration from Trading Card Games. Build an ever evolving deck to summon monsters and use powerful spells. Fuse, defend, open card packs, create new strategies. Repeat.

Treasure Defence is an award winning VR game that innovates on the classic tower defence genre. Play arcades, win towers and fight The Royal British Navy. Plunder gold from destroyed ships and fortify your pirate cove.

Flip Tower Defense on it's head in Flip TD. Flip your world upside down to defend with towers, upgrades, modifiers, powers, and more. Build custom worlds with the in-game world builder and share them online to compete for high scores in the community leaderboards.

Refactor is a hard-core tower defense game that combines modular building, route planning, and element composition.

Explore. Mine. Build. Fight. Destroy The Monoliths is a single-player real-time mining tower offense roguelike where you explore a randomly generated map, mine the terrain to get resources, and build turrets to both protect your base and fight monoliths that keep spawning ever more minions.

Portal of Defense is a strategy Roguelike tower defense game. The game can complete all operations by simply dragging and dropping with the mouse. Explore the portal and obtain powerful items to become stronger and resist the tide of enemy attacks.

Thorgard is a minimalistic viking base defense game. Defend your sacred meadhall against enemies.

Explore the mysterious Wall World on your giant robospider: mine for valuable resources, upgrade your equipment to fight off hordes of monsters, and discover exotic biomes in-between attacks. Will you be able to survive and learn the secrets of the Wall World?

Lanternia is a survival RTS with roguelite and deckbuilding elements. Build, defend, and expand the village in a dark wood, illuminated only with lanterns.

The Territory of Egg 2 is an unique tower defense indie game. Place Egg Towers, choose evolution branches, combine skills and build defenses. The souls of Heroic Eggs await your awakening! Explore and gather resources in the dark forest, unlock the technology tree, and defeat even stronger enemies!

"Final Resistance" It's a strategy game with a time-sensitive element. Control a castle under siege by monsters, gather resources within this prison-like castle, craft equipment, and arm your warriors.

An Exploration Tower-Defense Roguelite that lets you control the evolving map and monster spawns. Find resources, reveal encounters, adapt defenses, and enjoy endless replayability with procedural map/path generation and a quest/prestige system.

In The Rabbit Haul, you nurture your garden and upgrade your farm and abilities by day, and battle the mischievous Trash Panda Posse by night. Explore, strategize, and switch up your approach for optimal garden synergy and combat success in this unique take on tower defense.

Defenders of Cardom is a traditional tower defense game blended with deck-builder roguelite elements. Build your deck, play your cards right, and hone your strategy to defend against waves of enemies!

Creeping Dusk is a tower defense game. Build a town around an abandoned gold mine and defend against monsters that swarm the area. Fortify your defenses, and prepare for the increasingly challenging nights. Will you be able to protect your town from the encroaching darkness?

Immerse yourself in Nordhold: Origins, a tower defense game with high replayability. Build a medieval Nordic village, develop its economy, and defend it with unique towers and upgrades. Choose heroes and relics, compete on leaderboards, and aim for the Valhalla rank!

Conflict of Lords is an Roguelite Anti-TD game. You will act as the Lord of Foe in Game Development Council, who decided to go his separate way due to a conflict. Invade the newly released game Village Guardian. Summon the Predators to destroy villages. Try your best to overthrow the Overlord!

Roguelike tower defense where you craft your defense while controling your hero of choice. Navigate through procedurally generated maps and face unpredictable waves. Every run will offer a unique challenge that will make you adapt your strategy and master tower placement and upgrading!

A circuit-themed tower defense game: Build circuits that can survive the onslaught of electrical bugs. Discover new enemies, research new and upgraded towers, and protect increasingly complex circuit paths.

Fortress Fury is a survivor multiplayer tower defense roguelite. Endless hordes of enemies want to crush your tower! Buy weapons and upgrades to craft an array of overpowering builds. Will you be able to survive all waves and be the last tower?

"Slime Warfare" is a rogue tower defense game with a variety of gameplay and placement.Slimes are weak monsters and always bullied by humans. Players will play the role of the Slime Queen to build structures to defend against adventurers' attacks and strengthen themselves.

Cat Guardian is a flexible card game blending tower defense and survival. Manage resources, build, and strategize to protect the Tree of Hope from zombies. Can the cats of Meowx Planet succeed in their mission and survive? It’s up to you!

Gather and manage resources, defend your stronghold, explore and expand your kingdom and fight back against corruption.

The Territory of Egg is a unique twist on tower defense game. You need to build defense lines with egg warriors to protect the Holy Egg, the core of all eggs. Remember to upgrade your Tech Tree with the resources you've collected and unlock more skills to fight against the evil monsters.

Defend against the ongoing lizard problem in this dynamic tower defense where procedural, level-deforming earthquakes expand the available play area each wave. React to nature's forces and adapt to the changing terrain in order to survive.

Prepare for the onslaught! Chromatrix is a retro tower defense game where color and placement are everything. Upgrade and customize your turrets to counter shifting enemy-types and map configurations. Manage your resources and craft the perfect defense against any attack!

Defend your Chrysalis from growing hordes of monsters in this hybrid game that combines elements of tower defense, survival, and roguelike RPGs. Explore procedurally generated levels, possess and control animals, and grow deadly gardens. How far can you get before the next wave of monsters?

Defend your castle, mine for minerals, and level up your wizarding powers in this thrilling action-roguelike game. Grab your wand and prepare to fight off magical foes in this epic battle for survival!

Tower Factory is a tower defense and automation game with roguelite elements. Optimize resource production using conveyor systems while defending against monster waves. Can you find and destroy the enemy tower before it's too late?

Stop hordes of robots from destroying your Crystal shrine in this random shop tower defense game! Instead of choosing exactly what tower to place down, the random shop gives you 3 random towers to choose from. Set up your defenses and see if you can survive!