Top similar games like Deck Defense:

Rogue Tower is a tower defense game with roguelike elements and a continuously expanding path which you can influence. Unlock, build, upgrade, expand, defend.

Strategic roguelike tower defense game where you fortify your defense line by stacking cards in deckforts, play various cards on enemies and deployable grids, and receive general contributions to your defense from altar structures.

A hybrid card game and tower defence where the hands you play become the towers you build. Defeat the enemies approaching the bear's den and find modifiers that support the elements of your defensive strategy.

Card Conquest is a Tower Defense game with Deckbuilding and Roguelite elements. Combine spells, towers and units to create a deck and defeat your enemies. Spend your resources wisely and find balance between offense and defense. Gather powerful relics that will enhance your cards.

Defend your valuable chest in randomly generated maps with various towers, traps and obstacles to modify the path that the enemies must follow in "Digs: Prologue", the ultimate rogue-like tower defense game. Experience unique mechanics, upgrade your defenses and face off against challenging enemies

Rogue Cube Defense is a minimalist roguelite tower defense game with procedurally generated path that you gradually build up. Each run is different as the upgrades you get from leveling up are random. Pick your towers loadout and come up with the best strategy to beat the hordes of enemies.

A combination of Tower Defense and Rogue-like deckbuilding. Select your heroes, place towers, cast spells, research new technologies and build your deck to defend your castle from enemy forces.

TileDeck TD is a Deckbuilding Tower Defense with roguelike elements. Expand your kingdom, play powerful cards and build your perfect defensive setup.

Spliced is a hybrid roguelite deck-builder. Play as a symbiotic ooze, taking the parts and abilities of enemies you defeat. Use cards to battle enemies and navigate the environment.

Combine tactics and strategy in this roguelike deckbuilder, where you must build your deck, train and evolve your team. Step into a mystical world where the Genkai battle in a quest for power and harmony, and prepare for the imminent arrival of the Primal Genkai.

Gather together troops and weapons to fight through increasingly difficult armies in this medieval fantasy grid-based deck-building game. Establish synergies between your cards and treasures to create the strongest army!

Cards of Prophecy combines Tower Defense, Deckbuilding, and Roguelike elements, with huge inspiration from Trading Card Games. Build an ever evolving deck to summon monsters and use powerful spells. Fuse, defend, open card packs, create new strategies. Repeat.

Tower Knight is a deck-building & tower defense strategy game. Build your deck to strengthen your position, level up your knight, and win by capturing enemy towers.

Krumit's Tale, the second game in the Meteorfall universe, is a new take on the deckbuilding roguelike genre. Use your cards to clear dungeons, then upgrade your deck with new cards and perks to press forward. The fate of the world is in your hands.

Isle of Arrows is a Puzzle Tower Defense game in which you build a fortress in the sky. Place towers, expand the isle, and build your own paths. Can you find the perfect spot for each tile to beat the RNG and defend against waves of invaders?

Crystal Guardians prologue (small slice of the full game) is a tower defense game with rogue-like elements. Fight off waves and defend the base crystal. Gear up your towers with a powerful combination of items for your personal strategy. In a procedural map, find hidden powers and conquer the enemy.

A captivating blend of deckbuilding roguelike and tower defense genres. Craft your powerful deck, embark on a grand adventure through the Forest Kingdom, and wage epic battles against relentless enemy hordes. Are you ready to claim your throne in this unique fusion of cards and towers?

Build twisting mazes with tetromino blocks and deploy unique towers in this strategic roguelite tower defense adventure!

A classic rogue-like deck-builder game with some unique twists like Talent system and Random encounters and interesting Relics which change every run.

---

Nightmare has set its sights on this world, and as the will of the world, you will rely on cards, tower defenses, and urban construction to destroy Nightmare's invasion in the dream

A roguelite deck-building tower defense where every card you play shapes the battlefield! Draft a unique deck, summon powerful towers and traps, and unleash spells against waves of enemies. Explore with synergies, stack artifacts, and watch your strategy evolve as you forge the ultimate defense!

Every card is a weapon. Every decision matters. Battle through strange worlds and dangerous dungeons. Discover exotic weapons, powerful gear, and deadly skills. Burn, curse, explode, and smash your way to victory. Every run is different—just bring your best blades.

Deck of Defense is a deck-building, tower defense game where you place cards to defend your base. Craft a unique deck, upgrade your abilities, unlock game-breaking defense strategies, and see if your Deck of Defense can stand the test of time.

After an earthquake, you're sent to an island for rebuilding. Face nightly critter attacks, set up towers, and farm. Your mission is to seal the island or secure crops before defenses are breached. Now, grab your shovel and hammer, and enter the defensive battle!

A roguelike deckbuilder where alchemy fuels your cards, dice shape your fate, and sins whisper in your ear. Build your deck, forge your path, and decide what kind of soul you’ll become. All buffs react to one another as proper alchemy should do!

Slay the Spire meets Age of Empires! The roguelike deckbuilder where your cards are literally your weapons! Choose your wizard, build your deck, and become the best Castlemancer in the land!

A tactical deckbuilding game where you fight enemies, unlock cards, and build your deck before each battle—discard cards to generate energy and control the flow of every fight.

Dog and Goblin is an auto-battler Roguelike deck-building strategy game where you assemble a mixed army to stand against humans. With nearly 150 units across 19 different types, build your ultimate army and conquer their castles!

3D card building roguelike game, a tower climbing game where you can control two characters with independent card pools and turns, a favorite for Slay the Spire fans!

Portal of Defense is a strategy Roguelike tower defense game. The game can complete all operations by simply dragging and dropping with the mouse. Explore the portal and obtain powerful items to become stronger and resist the tide of enemy attacks.

"Zodiac Mountain" is a roguelike deckbuilder following the journey of a Panda as they adventure to become a Chinese Zodiac. Utilise dual hands of Yin & Yang, encounter fierce mythical characters, outskill your enemies in battle, and climb Zodiac Mountain.

Knight Dice is a turn-based dice game, upgrade and reroll your dice to defeat the dangerous enemies on your adventure.

Create the best set of magic scrolls to defeat waves of enemies.