Top similar games like Space Run:

Setting the bar as the definitive tower defense game, Defense Grid 2 introduces new worlds and threats to test your tower placement strategies. With a bold new look and the addition of new game modes, player-versus-player and multiplayer co-op, every play brings fun new opportunities and challenges.

Taur is an action-strategy sci-fi game. Control the Prime Cannon and unlock all of its powerful weapons and abilities. Build turrets, droids, aircraft and more as you fight to protect the homeworld of the Tauron droids against a relentless invasion. Will your Taur stand against the Imperion warmachine?

Ancient Space is a story driven single player real time strategy game where you take command of a fleet embarking on a scientific mission to chart undiscovered reaches of space called ‘The Black Zone’. Overcome overwhelming odds and fight for your life and the survival of your ship and its crew.

You think Tower Defense games are all about building? You thought wrong. Sanctum is not your average Tower Defense title. When the havoc starts, you get to join the fray! As one of the world’s first First Person Shooter - Tower Defense games, Sanctum has taken the best of both worlds to deliver an epic, one-of-a-kind experience.

The ultimate mash-up of Real-time Strategy and Tower Defense!

Defense Grid: The Awakening is a unique spin on tower defense gameplay that will appeal to players of all skill levels. A horde of enemies is invading, and it's up to the player to stop them by strategically building fortification towers around their base.

Exo TD is a true 3D space Tower Defense. Invaders have scouted your planet as their next target, you must protect it by building destructive turrets, orbital defenses, shields, drones and more to defend against the incoming invasion force.

Creeper World 3 is what happens when cellular automata takes over a strategy simulation. Instead of discrete units that attack your base, a fluid-like substance spreads over the terraformable terrain. Your base, your weapons, your strategy... you must adapt them all.

Sanctum 2 is the sequel to the world’s first Tower Defense/FPS hybrid game. Pick from four unique character classes and embark on a mission to protect the oxygen-producing Cores from hordes of deadly aliens who are threatened by their existence.

BAFTA award winning fleet-based RTS meets rogue-lite. In Distant Star: Revenant Fleet, build your fleet of up to 5 ships from a choice of 8 classes and traverse a randomly generated galaxy to defeat the Erebus Platform. NOW AVAILABLE ON MAC AND LINUX

Immortal Defense is a story-driven tower defense game in which you give up your body and life to become an immortal "path defender", and defend your home world from destruction, forever. The game takes place over millions of years. Is there anything you would give up everything to defend?

Anomaly 2 is a sequel to the critically acclaimed Anomaly Warzone Earth. Maintaining the core elements of the original, Anomaly 2 adds plenty of new features: unit morphing, over million tactical combinations, post-apo world and tower defense vs tower offense multiplayer mode.

You’ve been hired to make a delivery to planet Miridian V. The trip will be a dangerous yet lucrative journey full of mad robots and unpredictable stellar phenomenon. Name your crew, name your ship, manage your supplies, trade, battle, survive, and make your delivery!

"You are outgunned. You are massively outnumbered. You must win." These are your orders. Humanity has already fought its war against the machines -- and lost. AI death squads stand watch over every planet and every wormhole, the few remaining human settlements are held captive in orbiting bubbles, and the AIs have turned their...

Sci-fi Tower Defense real-time strategy with pleasant adaptive music. Play as a commander of a space station which got stuck in a time anomaly.

Fight off hordes of monstrous mutants created from a strange cataclysmic event in the new tower defense game, Prime World: Defenders. Join a group of exile treasure hunters who have ventured into the capital of an ancient empire, vast with mystery and danger.

Rocked by an explosive soundtrack, choose your band, place your equipments and defend the Rock 'N' Roll from everyone and everything who try to pull it down, on a totally hardcore tower defense!

Lead an armored squad through the perils of this reversed tower defense action-strategy game!

Build your defense base to repel alien invaders. Atahion is a strategy and tactical defense game in which you have to extract resources, build defense towers and use bonuses to complete the mission.

Jump in to intense turret defense action with Sol Survivor! Build turrets to defend your colony and the innocent colonists within. Smash enemies with volleys of actively-controlled orbital support. Play with friends in co-operative and competitive multiplayer matches or test your mettle against our new Survival mode!

Battlevoid: Harbinger is a hard sci-fi space exploration game blending roguelike, turn-based, star map strategy, and real-time space battles. You are a young commander venturing out into enemy territories, to unknown galaxies, never knowing what you will face as you jump out from hyperspace.

A spaceship building and universe-exploration game. Collect resources, expand and grow your fleet, and conquer your personal galaxy. Stellar ambience by Peaks.

This "spaceship simulation roguelike-like" allows you to take your ship and crew on an adventure through a randomly generated galaxy filled with glory and bitter defeat.

You believed tower defense is only about building towers? That's not quite right – because AIRA VR is not like other tower defense games in virtual reality. Once the battle starts you find yourself in the midst of the fight!

Gear up and get going! Defend your outposts from waves of alien enemies with your mech. Build and upgrade your base, protecting the extraction of the mysterious planetary system’s rich resources!

Slice them, burn them, skewer them, and launch them - no matter how you get it done, orcs must die in this fantasy action-strategy game from Robot Entertainment.

You have 9 days to find a safe place on the planet. Your ship is low on fuel and you have to land. Setup sentry guns around you to defend yourself while you collect more fuel for the ship. AI controlled Drones and Tanks attack you trying to find weaknesses in your defenses.

The ultimate space capital ship combat compendium is the evolution of hard core space combat sims. The only game of its kind currently in existence.

The Rift is a tower defense game with elements of RPG gameplay that will appeal to players of all skill levels. Enemies from an alternate universe are attacking and it's up to the player to stop them by strategically building defensive towers.

Out There is an award-winning space exploration game blending roguelike, resource management and interactive fiction.

Become the Captain of an interstellar cruiser and journey across the galaxy to save the Republic. During your journey you will have to make important decisions, improve the weaponry of your ship and fight against numerous enemies.