Top similar games like Powerup Humans:

Pixel Defender is a 2D tower defense game with retro pixel aesthetics and direct character control.

Prevent the invasion of the minions that stimulate the desire for challenge and prove that you are a slayer physically and mentally.

Fable Forts! TD: defend your fairy kingdom from stupid human invaders!

This game is a arcade block placing game mixed with action-packed Tower Defense gameplay mechanics. Build forts out of tetrominoes high up in the sky and defend it against the incoming waves of airships, by shooting at them with your minigun and building defenses!

Kingdom Eighties is a short story-based standalone expansion set in the Kingdom universe. An epic singleplayer adventure of micro-strategy and base building. Defend your town against the mysterious Greed, and discover the secrets of your family lineage!

An arcade strategy game about defending your garden. Grow potatoes, onions and carrots to defend your lawn!

Build your defense base to repel alien invaders. Atahion is a strategy and tactical defense game in which you have to extract resources, build defense towers and use bonuses to complete the mission.

A minimalist game about building and defending your little kingdom.

Gather bees to fight hordes of enemies in this RogueLike TowerDefense, collecting various relics to become the most powerful and defeat all those who get in your way.

Defend your base from hordes of sheep. Fight as a hero with powerful abilities or shapeshift into a flying eyeball god to traverse the battlefield and command troops. Build your defenses and economy while maximizing auto-battler inspired synergies that unlock power-ups for your hero and defenses.

A strategic tower-defense where you control powerfull drones. Unlock new tower and use specific technologies to defend your base on Thukothea!

Tiny Battles is a tactical action auto-battler where battles take place automatically in the arena.

Tower Field is a roguelike tower defense game with a random generated world to explore and modular towers that you can customize and adapt to protect yourself from the dangers you discover.

As the kingdom's most promising pioneer, embark on a legendary journey to tame the frontier! Build thriving towns across various landscapes, fending off waves of diverse enemies until you establish a firm foothold and have explored everything the eye can see!

Laser Defense Extreme is a Tower Defense Game, with a Killstreak System. Place your "Towers" strategically and eliminate the incoming enemies.

Defend the galaxy against a slimey pandemic in this classic Tower Defence game. Build towers to defend these planets and strategize against the infection.

Summon troops and use magic to defeat mage lords and other foes while surviving attacks from their followers. Learn new spells and recruit troops with unique powers. Venture across the land, battling ever stronger enemies until reaching the evil Mage King.

Dive into 1BIT CASTLE: REMAKE, a strategic action-packed tower defense game. Choose heroes and perks to fight off evil monsters. Enjoy captivating pixel art while protecting your treasures in this addictive adventure with endless mode!

"Relic Guardian" is a fantasy style strategy tower defense game. As the builder on the battlefield, summon a variety of defense towers and spells with reliable hero companions to complete this epic and guarding adventure!

Defend against interdimensional (wow!) monsters in this open field (huh?) tower defense game.

Rise Eterna War tells the bloody tale of Arthbane, a great general who led the last stand to reclaim his homeland Ars Rare from foreign invaders. Play as Arthbane, 10 years before the events of Rise Eterna, rallying loyalists in a desperate bid to seize the capital Gaiacus.

Last Outpost is a minimalist Base Building & Strategy game where you build and defend your outpost in zombie apocalypse.

Build Defenses and Battle against the Clockwork horde in this 2D Action RPG / Tower Defense hybrid. Experience a gripping story, which unfolds as you progress through 75 Days of warfare, aided by a collection of turrets, traps and special attacks.

Building defender 2D strategy game! Place building and gather resources. Use the resources you collect to then build towers that will defend your heart in the middle of the map. Survive as many levels as you can manage! Good luck!

Swallow’s Keep is a place of great prosperity; however, not all lands share in its wealth, and it has caught the eye of ambitious adversaries. Can you defend your home against the bandits?

“Natti” is a roguelike tower defense game unfolds in the Otherworld of Korean folktales. Place defense towers, collect equipment, and strategically utilize various heroes to defeat all the monsters and protect the Otherworld with “Natti”, goblins in form of animals.

Prepare for an epic battle in this captivating tower defense game! Build, defend, and triumph as you strategically place towers, manage resources, and upgrade your arsenal to fend off relentless waves of enemies.

A tower defense game filled with 12 varied levels across 7 biomes and 14 unique monsters with 3 increasingly harder difficulties to challenge even the most experienced of tower defense gamers lurking in their strongholds.

Real-time resource / defense game. Advance your build level by destroying enemies. Enemies are spawned from camps on either side of your territory. Eliminate the camps (and all spawned enemies) to end the raids and conquer the Scenario.

ProtectHeart is a strategic defense game, defend the heart at all costs! Are you up for the challenge?

Dark facets is a 2d strategy action game in the tower defense genre with the unusual mechanics and a unique storyline. In the role of a dark magician, you will have to build your own citadel, mine resources and engage in battle with a dangerous enemy.

Phoenix Hope is a pixel art 2D real-time, side-view strategy game in which you must develop your colony during the day and repel waves of monsters at night.

Defend your castle in this fast-paced tower defense/action hybrid game with stunning pixel art graphics! Play as alchemically enhanced warrior Bellator, set traps, build towers, craft powerful weapons, and defend your home! The fate of the castle lies in your hands!

Command your troops through an epic (mis)adventure as you defend exotic lands from dragons, man-eating plants, and ghastly denizens of the underworld -all with flashy new towers, levels, heroes, and more goodies to help you crush your foes in this Fantasy Action Tower Defense game!

The goblin tribes of the realm have united against you and the power of the Eye of the Void. Build towers, fortify walls, construct gold mines to gather resources, and cast powerful spells to fend off waves of determined goblins and their allies who seek to destroy you.

Chrono Crystal is a tower defense game. Spanning across 5 major regions with the Prince and facing numerous challenges, an unprecedented great war is about to break out. Build your towers, upgrade your heroes, and defend your crystal against waves of enemies—until the countdown timer runs out!