Top similar games like Slay the Spire 2:

Cardseer is a deckbuilding game combining roguelike elements with a sprawling campaign. Choose your hero and fight your way across diverse maps filled with fearsome enemies, all while crafting your deck and collecting powerful artifacts. Can you rise to the challenge?

Destiny or Fate is a deck-building roguelite game. Choose a hero, build a deck and a party of mythical creatures, and set out on an endless adventure! Are you ready to make your own destiny, or will you succumb to an evil fate?

All the strategic depth of deckbuilding classics taken to the extreme! Manage combat on a tactical map, pursing divine boons and avoiding the deadly spread of corruption in Waystones, a turn-based roguelike deckbuilder!

This card game combines elements of roguelike and deckbuilding. During the game, you shall strive ahead, gathering cards to build a unique deck and use it to defeat the enemies getting in your way. You will have to choose between escaping or try to defeat Death, who is relentlessly pursuing you.

Unlike other single player deckbuilder, you are going to fill a bag with black and white stones. Wether you can use your skills depends on the order you pick the stones. Build a unique combo, defeat powerful enemies, and don't forget to use your Prescience!

Poker Quest is a fantasy roguelike where players use a standard 52-card deck to take on fierce enemies in epic battles. Featuring over 20 unique heroes, thousands of items, and deep gameplay that will test even the most experienced players.

We fused card games and roguelikes together to make the best single player deckbuilder we could. Craft a unique deck, encounter bizarre creatures, discover relics of immense power, and Slay the Spire!

Reincarnation is a medieval/fantasy themed turn-based RPG card game with unique deck-building, character development and class selection experiences. Devise your attack and defense strategies to defeat monsters and gain rewards. Join the action-packed world of Reincarnation today!

A roguelike deck-building game where you craft a deck, spark talents, discover runes, and assemble your team with partners' cards! Play unique stories for every character and explore a world caught in the clash of gods. New Puppeteer DLC just released!

Fuse cards together in this roguelike deckbuilder to unleash their full potential. Discover powerful fusion combinations, build decks with potent synergies, harness abilities from ancient runes, and defeat challenging enemies on your quest to restore peace to the realm of Erdia.

Noyah: Corrupted Memories is a roguelike deckbuilder, in pixel art, with random battle generation, day and night cycle, climate events, advanced rune system, that allows you to create endless possibilities with a single card.

Dreamshard is a rogue-like deck-building game where slay the spire meets hearthstone. Explore procedurally generated dungeons, fight monsters, craft a unique deck and defeat your enemies to find the secret of the Dreamshard.

Dive into a unique fusion of classic RPG and deckbuilding, where epic adventures meet strategic card battles. Ascend the Tower of Legends, build your own deck, confront fearsome monsters, and forge your own destiny.

An astronomical roguelike deckbuilder game. Fight the Olimpians while each Zodiac sign affects your cards differently in a deeply satisfying card game. Fight Greek beasts, discover Tarot Cards and climb the Olimpus searching for revenge.

Hunt through the wastelands for colossal Beasts in this roguelike deckbuilder. Beware! Beasts grow stronger during battle, allowing them to consume your creatures or counter your spells. Carve profane Gifts from these behemoths and grow stronger to serve your Patron! But serve them to what end?

Neurodeck is a psychological deckbuilding card game to challenge your fears. Build your deck & capacities by answering personality tests, visiting rooms or meditating. Face your phobia and defeat them through the power of life-inspired cards.

Dreamgate is a unique hardcore mix of deck building card battler, roguelite adventure and RPG. Build your deck, explore the Dreamgate world and defeat fearsome foes!

Folktale Misfits is the card game roguelike where you play as outcasts looking for answers in a whimsical world. Develop strategies and help the misfit heroes unlock their true potential.

Dungeon Decks is a roguelike deckbuilding game where you create custom characters, craft unique decks, and recruit up to 4 allies. Collect powerful party buffs, battle monsters, and choose your own path in procedurally generated dungeons!

Spellrune is a singleplayer collectible card game with rogue-like and role-playing elements set in a fantasy world. Take the role of a wizard apprentice, build a powerful spell deck, defeat hordes of creatures and collect magic artifacts.

Spliced is a hybrid roguelite deck-builder. Play as a symbiotic ooze, taking the parts and abilities of enemies you defeat. Use cards to battle enemies and navigate the environment.

Northwind is a monster-hunting rogue-lite deckbuilder. Hunt monsters, gather resources, and explore card crafting in Northwind Town. Discover new monsters and unlock town upgrades as you increase your hazard level.

Dark Mist is a card game that combines elements of the roguelike deckbuilder genre with enemies that appear in waves. Defeat monsters and level up during battle to keep yourself going.

Dark Crown is a roguelike deckbuilder where a new take on chess meets powerful magical abilities. It's a gloomy and oppressive world, but one that you will conquer by unlocking new cards, improving units, making sacrifices, and tough choices to grow more powerful with each new run.

Your deck is your health in BeaureCard, an easy to learn fast-paced roguelike deckbuilder. Strive to deplete your opponents' deck, cleverly using traps, powers, blessings, and curses. Embark on an epic adventure, with exciting events to explore, new cards to acquire, and dangerous demons.

Become a giant walking dice, explore dungeons and defy Lady Luck in this dice powered roguelike! Now featuring "Reunion", a free DLC with six brand-new episodes!

Explore the galaxy in this deckbuilding, sci-fi roguelike where ship upgrades and crew management are key to your survival. Optimize resource generation, engage in intense turn-based battles, and take on ever-growing threats as you seek out The Signal.

Become a master hacker in this Cyberpunk Roguelike Deckbuilder. Explore the dangers of cyberspace and fight evil corporations. Build and upgrade a deck of powerful programs. Unlock perks and skills, and unleash digital hell on your enemies. Dive Into The Grid!

Iris and The Giant is a fusion of the CCG, RPG and roguelike genres. You play as Iris, who must brave her fears in her imaginary world. Dive into a melancholic and gripping adventure, filled with cute monsters and buried memories. Ready to face your inner demons?

A fusion of roguelite, tower defense, city-building, and deck-building! We created a new kind of real time strategy game filled with addictive and fast-paced gameplay. Create your deck, defend your city, and build the largest Ratropolis in history!

Escape a treacherous labyrinthine prison by outsmarting guards in tactical card-based battles. Pick your abilities before each encounter, tailoring your strategy. Defeat guards to steal their skills, navigate deadly traps, and unleash your cunning to secure your freedom.

Astrea is a DICE-deck-building roguelike that flips the script on deckbuilders by using dice instead of cards and a unique dual “damage” system: Purification vs Corruption. Build a dice pool strong enough to purify Astrea's out-of-control corruption and save the Star System.

Lucky Hand is a roguelike deckbuilding game where every card drawn shapes your fate. Build powerful decks, strategize against challenging enemies, and explore dangerous places. With each battle, unlock new cards to help you in your adventure!

Embark on a thrilling deckbuilding adventure, fighting your way to the final boss on a journey that's different every time.

Embark on a journey through the fading world of Everwayne, unravel all of its secrets, untangle the personal stories of characters, collect various unique cards for each character, and battle your enemies.

A roguelike deckbuilder where you play as a witch studying wacky schools of magic like Llamamancy and Spookymancy. Summon monsters to fight for you. Scrounge together components to cast powerful spells. Mix and match spell combos as you journey for lost astral knowledge.