Top similar games like Slay the Spire 2:

All the strategic depth of deckbuilding classics taken to the extreme! Manage combat on a tactical map, pursuing divine boons and avoiding the deadly spread of corruption in Waystones, a turn-based roguelike deckbuilder!

Little Adventure tale is a Roguelike Deckbuilder set in a cute fantasy world where you can enlist the help of the Guild to Hire companions and manage several Card Decks & Accept Quests to earn more rewards! All this in order to banish the Evil Lord Obradin!

We fused card games and roguelikes together to make the best single player deckbuilder we could. Craft a unique deck, encounter bizarre creatures, discover relics of immense power, and Slay the Spire!

Hunt through the wastelands for colossal Beasts in this roguelike deckbuilder. Beware! Beasts grow stronger during battle, allowing them to consume your creatures or counter your spells. Carve profane Gifts from these behemoths and grow stronger to serve your Patron! But serve them to what end?

Poker Quest is a fantasy roguelike where players use a standard 52-card deck to take on fierce enemies in epic battles. Featuring over 20 unique heroes, thousands of items, and deep gameplay that will test even the most experienced players.

The combination of CCG, roguelike, and tactical gameplay with an interactive environment offers a unique experience! Build your own deck, join battles and quests, obtain powerful artifacts by cunning or force, and uncover the mystery of the Stone of Adventure!

Destiny or Fate is a deck-building roguelite game. Choose a hero, build a deck and a party of mythical creatures, and set out on an endless adventure! Are you ready to make your own destiny, or will you succumb to an evil fate?

Reincarnation is a medieval/fantasy themed turn-based RPG card game with unique deck-building, character development and class selection experiences. Devise your attack and defense strategies to defeat monsters and gain rewards. Join the action-packed world of Reincarnation today!

This card game combines elements of roguelike and deckbuilding. During the game, you shall strive ahead, gathering cards to build a unique deck and use it to defeat the enemies getting in your way. You will have to choose between escaping or try to defeat Death, who is relentlessly pursuing you.

Tactical Roguelike Deckbuilder with ability-based combat, fueled by card synergies. Build a powerful deck to support your hero. Use abilities to wipe out hordes of enemies. Discover powerful combos within the near-endless variety of composite cards.

Cardseer is a deckbuilding game combining roguelike elements with a sprawling campaign. Choose your hero and fight your way across diverse maps filled with fearsome enemies, all while crafting your deck and collecting powerful artifacts. Can you rise to the challenge?

Dreamshard is a rogue-like deck-building game where slay the spire meets hearthstone. Explore procedurally generated dungeons, fight monsters, craft a unique deck and defeat your enemies to find the secret of the Dreamshard.

Mutant Kingdom thrusts you into a haunting, ever-changing world where survival hinges on clever deckbuilding and tactical exploration. Harness the power of dynamic weather and elemental synergies, discover game-changing items, and unleash adrenaline-pumping combos.

Neurodeck is a psychological deckbuilding card game to challenge your fears. Build your deck & capacities by answering personality tests, visiting rooms or meditating. Face your phobia and defeat them through the power of life-inspired cards.

Lucky Hand is a roguelike deckbuilding game where every card drawn shapes your fate. Build powerful decks, strategize against challenging enemies, and explore dangerous places. With each battle, unlock new cards to help you in your adventure!

Dive into a unique fusion of classic RPG and deckbuilding, where epic adventures meet strategic card battles. Ascend the Tower of Legends, build your own deck, confront fearsome monsters, and forge your own destiny.

Fuse cards together in this roguelike deckbuilder to unleash their full potential. Discover powerful fusion combinations, build decks with potent synergies, harness abilities from ancient runes, and defeat challenging enemies on your quest to restore peace to the realm of Erdia.

Dungeon Decks is a roguelike deckbuilding game where you create custom characters, craft unique decks, and recruit up to 4 allies. Collect powerful party buffs, battle monsters, and choose your own path in procedurally generated dungeons!

An astronomical roguelike deckbuilder game. Fight the Olimpians while each Zodiac sign affects your cards differently in a deeply satisfying card game. Fight Greek beasts, discover Tarot Cards and climb the Olimpus searching for revenge.

Dark Mist is a card game that combines elements of the roguelike deckbuilder genre with enemies that appear in waves. Defeat monsters and level up during battle to keep yourself going.

A roguelike deck-building game where you craft a deck, spark talents, discover runes, and assemble your team with partners' cards! Play unique stories for every character and explore a world caught in the clash of gods. New Puppeteer DLC just released!

"Castle Morihisa" is a roguelike featuring strategic deckbuilder. You need to build up your deck through constant battles, acquire powerful talents, and wield the power of the Fallen Heroes to unveil the truth behind the rebellion in Castle Morihisa.

Unlike other single player deckbuilder, you are going to fill a bag with black and white stones. Wether you can use your skills depends on the order you pick the stones. Build a unique combo, defeat powerful enemies, and don't forget to use your Prescience!

A roguelike, deckbuilder game with a twist, tactical combat, and huge replayability. Collect cards, traverse the dark lands, battle elusive enemies, and grow your town - as you push deeper into the chasm of madness.

Spliced is a hybrid roguelite deck-builder. Play as a symbiotic ooze, taking the parts and abilities of enemies you defeat. Use cards to battle enemies and navigate the environment.

Folktale Misfits is the card game roguelike where you play as outcasts looking for answers in a whimsical world. Develop strategies and help the misfit heroes unlock their true potential.

Deck-building turn-based slot machine battling adventure. Fight evil fruits aside your battle buddy slot machine to save your village. Spin your destiny and grab the precious loot in a fast paced colorful adventure.

A combo-based deckbuilding roguelike through a space-time loop: collect cards, receive blessings, add pets to your party, and grow stronger. Chain together cards in the right order for max power, and act before the enemy does. Build synergistic decks, find many secrets, and make BIG numbers!

A roguelike deckbuilding game where rogues are summoned to defeat dark forces of evil. Summon historical heroes, tame mythical beasts, and evolve them in your adventure!

Dreamgate is a unique hardcore mix of deck building card battler, roguelite adventure and RPG. Build your deck, explore the Dreamgate world and defeat fearsome foes!

Become a giant walking dice, explore dungeons and defy Lady Luck in this dice powered roguelike! Now featuring "Reunion", a free DLC with six brand-new episodes!

Discover an endlessly replayable roguelike deckbuilder. Craft a unique deck, collect powerful relics, harness potent magic and enhance cards with "Boost" to overcome the challenges ahead as you set out to Seal the Rift!

A roguelike deckbuilder where you play as a witch studying wacky schools of magic like Llamamancy and Spookymancy. Summon monsters to fight for you. Scrounge together components to cast powerful spells. Mix and match spell combos as you journey for lost astral knowledge.

Assemble a team of Heroes to take down the AI overlord in this roguelike auto-battler. Master the elements, manage your timeline and build the strongest team possible.

A Roguelike Deckbuilder with fun card fusion and transformations. Combine different cards to create powerful combos and generate power cells that can be used to unlock special abilities. Collect four identical cells to transform Dala into special forms to take on powerful mythical creatures.