Top similar games like Slay the Spire 2:

All the strategic depth of deckbuilding classics taken to the extreme! Manage combat on a tactical map, pursuing divine boons and avoiding the deadly spread of corruption in Waystones, a turn-based roguelike deckbuilder!

Little Adventure tale is a Roguelike Deckbuilder set in a cute fantasy world where you can enlist the help of the Guild to Hire companions and manage several Card Decks & Accept Quests to earn more rewards! All this in order to banish the Evil Lord Obradin!

We fused card games and roguelikes together to make the best single player deckbuilder we could. Craft a unique deck, encounter bizarre creatures, discover relics of immense power, and Slay the Spire!

Hunt through the wastelands for colossal Beasts in this roguelike deckbuilder. Beware! Beasts grow stronger during battle, allowing them to consume your creatures or counter your spells. Carve profane Gifts from these behemoths and grow stronger to serve your Patron! But serve them to what end?

Destiny or Fate is a deck-building roguelite game. Choose a hero, build a deck and a party of mythical creatures, and set out on an endless adventure! Are you ready to make your own destiny, or will you succumb to an evil fate?

Reincarnation is a medieval/fantasy themed turn-based RPG card game with unique deck-building, character development and class selection experiences. Devise your attack and defense strategies to defeat monsters and gain rewards. Join the action-packed world of Reincarnation today!

This card game combines elements of roguelike and deckbuilding. During the game, you shall strive ahead, gathering cards to build a unique deck and use it to defeat the enemies getting in your way. You will have to choose between escaping or try to defeat Death, who is relentlessly pursuing you.

Cardseer is a deckbuilding game combining roguelike elements with a sprawling campaign. Choose your hero and fight your way across diverse maps filled with fearsome enemies, all while crafting your deck and collecting powerful artifacts. Can you rise to the challenge?

Dreamshard is a rogue-like deck-building game where slay the spire meets hearthstone. Explore procedurally generated dungeons, fight monsters, craft a unique deck and defeat your enemies to find the secret of the Dreamshard.

They lied about the magic being low. A dark fantasy roguelike deckbuilder where victory matters - beat the game with one class, their magic unlocks for all others. 3 classes at launch. Optional dungeons. Gods who answer prayers. Vibrant fantasy descending into cosmic horror.

Neurodeck is a psychological deckbuilding card game to challenge your fears. Build your deck & capacities by answering personality tests, visiting rooms or meditating. Face your phobia and defeat them through the power of life-inspired cards.

Tactical Roguelike Deckbuilder with ability-based combat, fueled by card synergies. Build a powerful deck to support your hero. Use abilities to wipe out hordes of enemies. Discover powerful combos within the near-endless variety of composite cards.

Dive into a fusion of classic RPG and deckbuilding, where epic adventures meet strategic card battles. Ascend the Tower of Legends, build your own deck, confront fearsome monsters, and forge your own destiny.

Lucky Hand is a roguelike deckbuilding game where every card drawn shapes your fate. Build powerful decks, strategize against challenging enemies, and explore dangerous places. With each battle, unlock new cards to help you in your adventure!

Poker Quest is a fantasy roguelike where players use a standard 52-card deck to take on fierce enemies in epic battles. Featuring over 20 unique heroes, thousands of items, and deep gameplay that will test even the most experienced players.

Fuse cards together in this roguelike deckbuilder to unleash their full potential. Discover powerful fusion combinations, build decks with potent synergies, harness abilities from ancient runes, and defeat challenging enemies on your quest to restore peace to the realm of Erdia.

In this roguelike deckbuilder, every card features its own dice. Battle against many fantastic creatures across 3 chapters. Upgrade your cards, build countless synergies and find mighty weapons to shape your playstyle. There is only one goal: Be the hero, slay the dragon.

This roguelite deckbuilder is set in the American West. Battle monsters, cultists, and folkloric creatures while searching for gold and the source of the evil within a mine. You choose when to leave, not where to go. Will you play it safe returning to the surface, or risk it all by going deeper?

Dungeon Decks is a roguelike deckbuilding game where you create custom characters, craft unique decks, and recruit up to 4 allies. Collect powerful party buffs, battle monsters, and choose your own path in procedurally generated dungeons!

Arcane Veins is a roguelike deckbuilder. Build your deck, chain together spells in your wand, and overpower your enemies as you descend through the darkness uncovering all the secrets the cave has to offer.

Dark Mist is a card game that combines elements of the roguelike deckbuilder genre with enemies that appear in waves. Defeat monsters and level up during battle to keep yourself going.

Northwind is a monster-hunting roguelite deckbuilder with a tug-of-war combat twist, card crafting, and a mana management system inspired by Magic: The Gathering.

A roguelike deck-building game where you craft a deck, spark talents, discover runes, and assemble your team with partners' cards! Play unique stories for every character and explore a world caught in the clash of gods. New Puppeteer DLC just released!

In Deathless, elements of a collectible card game, roguelike, and turn-based strategy combine seamlessly. Build a unique deck of cards, discover unusual relics, and defeat legendary bosses. No two journeys will ever be the same with endless Path. Crush the Evil and save the world!

"Castle Morihisa" is a roguelike featuring strategic deckbuilder. You need to build up your deck through constant battles, acquire powerful talents, and wield the power of the Fallen Heroes to unveil the truth behind the rebellion in Castle Morihisa.

Unlike other single player deckbuilder, you are going to fill a bag with black and white stones. Wether you can use your skills depends on the order you pick the stones. Build a unique combo, defeat powerful enemies, and don't forget to use your Prescience!

In this roguelike deckbuilder, you’re hunted by an Eldritch Horror. Build crushing combos, fight coordinated enemies, and reroll your abilities to survive. Infinitely upgrade weapons, forge killer synergies, and become stupidly overpowered!

Spliced is a hybrid roguelite deck-builder. Play as a symbiotic ooze, taking the parts and abilities of enemies you defeat. Use cards to battle enemies and navigate the environment.

Bring revolution to the skies in this party-based deckbuilder with roguelite storytelling. Navigate treacherous sky islands, build unique decks for a crew of unlikely heroes and breach the storm to uncover the true cost of power.

Take deckbuilding to the next level. Transform your hand of cards into a tactical grid of runes. Plan, shift, and strike to unleash powerful combos and chain match-3 bonuses. Choose your hero, master their deck, and fight through deadly dungeons to face a mysterious dark overlord.

Through Hell and Back is a timeline based roguelike deckbuilding game. Place your spells on the Timeline to outsmart your enemies. Choose your power ups carefully, trade spells and upgrade the Timeline to unleash devastating combos.

Tame legendary beasts, evolve them into powerful forms, and fuse them with historical heroes in this roguelike deckbuilder. Master deep strategy and build unstoppable synergies to conquer every run!

Inkborn is a roguelike deckbuilder with a card system built around chaining Glyph-based combos. Sequence your cards in tactical combat to unleash impactful effects. Customize your Skill Tree before each run, evolve new abilities and uncover the hidden story of a world folded in ink, metal and paper.

Deck-building turn-based slot machine battling adventure. Fight evil fruits aside your battle buddy slot machine to save your village. Spin your destiny and grab the precious loot in a fast paced colorful adventure.

Folktale Misfits is the card game roguelike where you play as outcasts looking for answers in a whimsical world. Develop strategies and help the misfit heroes unlock their true potential.

Discover infinite cards in this roguelike deckbuilder. Every card is unique, every run a new experience. Craft, combine, and build your deck completely freely to defeat enemies and bosses, or take on cleverly designed puzzle challenges!