Top similar games like Mutation Surge:

Microbes and Machines is a roguelite action game where you control a little bubble robot that fights against the forces of evil.

Drawn into your PC by an antivirus, control a multi barrel tank in this Action Roguelike, 2D Shooter. Defeat motherboard viruses to unlock new zones. The 'UPGRADE MACHINE' grants enhancements every 1-10 seconds. Use points to add upgrades in this Arcade, Top-Down Adventure.

Step into the shoes of Aetherion's newest agent and join them on their quest for infinite energy. Choose your playstyle and weapons, upgrade your equipment, and complete your missions to become stronger and survive on planet 347TH2-Terminus in this fast-paced roguelike-metroidvania.

Core Breach is a fast-paced, twin-stick arcade shooter in a pixel art style. Play as a Trojan worm virus, outmaneuvering and destroying antivirus enemies. Upgrade your worm with powerful attacks and skills as you fight to breach the CPU core and uncover its secrets

Go To Heck is a fast-paced 2d sidescrolling action roguelite, descending through Cyberheck and using your railgun to destroy all the devils in your way.

A rogue-like arcade shoot-'em-up.

Challenge the tower solo or co-op in this high-octane sky crawler action rogue-lite. Stack power ups and steal destructive weapons as you dodge, dash and mutilate your way to the top. Your retribution awaits.

You are military volunteer. what? you did not volunteer? It's too late! You are already in the middle of the battlefield. kill the alien for the humanity! Marine Survivors is simple action rogue lite game. kill aliens, earn exp gem, upgrade your weapon. unlock various collection.

Fast paced Top-down shooter! Smartly use IRCM to evade the constant barrage of bullets and missiles and destroy everything that stands in your way.

Regulators is a tactical top-down shooter where you lead a team of mercenaries to clear the city from mutating villains using your weapons, gadgets, special super powers and intelligence.

This is a rogue-like top-down shooter where you control a spaceship that is sent out to explore the caves on the Moon. Once you enter the caves, you find out that there are enemies. It is up to you to survive against them while also trying to find the path down to the next level of the caves.

Frontline Survivors is an intense top-down shooter with roguelite elements that puts you in the boots of a soldier fighting for survival on the battlefield. With countless enemies coming at you from all sides, you will need to use all your skills and strategy to stay alive.

This is a hardcore physics-action game that rewards skillful maneuvering and tactical thinking with satisfying, robot-smashing action! Survive long enough to learn about secret AI society, and discover the truth behind the ROBOT RECKONING.

ArrowMongers is a top-down 2D shooter, in a mix between a roguelite dungeon and a level based colosseum! Fight your way through the procedural dungeon while using tons of different arrows, clear the 100-floors colosseum, and become a legendary archer in the ArrowMongers village!

Fight hordes of Covenant & Flood in this new game mixing Roguelite & Bullet Heaven for hours of mindless fun!

Pewt 'em Up! is a retro inspired arcade space shoot 'em up with lots of upgrades, achievements, extras and more.

Survive Planet Yubglub is a survival rouge-lite, where Earth Representatives must hurl dodgeballs while evading toxic slime aliens and their lethal projectiles. The Earth Reps. must carefully navigate through the harsh environment of planet Yubglub. Choose your character, and Survive Planet Yubglub!

Face endless waves. Dodge. Survive. Repeat. Vengeance is a fast-paced 2D bullet hell roguelike where you're thrown into a chaotic battlefield swarming with enemies. Master your movement, survive as long as you can. Every second counts, and one wrong step means game over.

Dive into a fast-paced underwater roguelike! Battle swarms of sea creatures, cursed pirates, and colossal bosses as you explore unique aquatic biomes. Collect a variety of weapons, uncover treasures, and survive the unknown in an epic journey through the ocean depths!

Nemesis Shock is a twin stick shooter rogue-lite. Take control of your prototype mech, the Nemesis, and cut though hordes of enemies. Use your quick movements and overwhelming firepower to survive.

Roguelike Shooter Where Your Bullets Hurt You!

Explore a world where cyberpunk and magic collide with the eccentric protagonists. With them by your side, you're sure to encounter some unwanted situations!

Void Heart is a frenetic 2D action rogue-lite platformer with a character development system. You will go through various rooms destroying enemies and collecting items that will help you in the battle against the bosses. Enemies will become tougher with each level you complete. No checkpoints.

Rejected as heir after losing your will, you must survive on an abandoned amusement-park planet. Gather ingredients, craft food-guns, shoot, eat, and grow stronger to reclaim your lost legacy.

Consume the civilization of the fools who unleashed you upon the universe. Become the Empire Ender.

Space Ace is a 2D top-down shooter that focuses on upgrading your ship to fight through levels of Bosses and smaller enemies. Play with keyboard + mouse or Xbox controller.

A twin stick shooter without the twin stick, Gunlocked is a sci-fi action roguelike about careful positioning and upgrade selection. Manage unique targeting systems across multiple weapons and upgrades, as you battle legions of alien ships, and then do it all over again!

Enter the chaotic world of Exo Helljumper: Descent X, filled with mutated foes and lurking dangers. Combine items and strategy to conquer relentless levels. Face unique foes and formidable bosses, test your cunning and skills, and feel the thrill of battle as you push beyond your limits!

Rotten Survivor is the ULTIMATE 2D top-down horde survivor game! Fight massive hordes of bizarre enemies! Upgrade your equipment, create crazy combinations between all of the different weapons and modifiers and become an unstoppable force!

Discvivors is a timed survival, bullet hell, roguelite game which grows more intense over time. With more RPG style progression and unlocks than most games of the genre, permanently improve the classes you want and unleash hell on your enemies to become the ultimate survivor.

Gun Garden is a dungeon crawler top-down shooter with rogue-like elements. Explore rooms, find gear, fight enemies, and level up your stats as you progress through the various floors, attempting to find the lost treasure of the Gun Garden.

Exosoul is an adrenaline-fueled top-down shooter that will test your skills and reflexes. Fight for your life against relentless enemies while trying to synchronize your body and soul. You have a powerful arsenal of weapons at your disposal, but you'll need to use them wisely if you want to survive.

Seedovia is a rogue-like dungeon crawler where you traverse room after room, fighting challenging monsters. Chain your weapons, collect game-changing passive upgrades, and equip items to create unique builds and become increasingly more powerful.

The universe is yours to conquer in That's My Space. Gather resources, craft powerful weapons, upgrade your spaceship and battle against enemy nations to become the ultimate space explorer.

Meow Legion is a game about assembling an army of cats to defend against waves of enemies.A top-down roguelite shooter game where you hire cats and level them up to fight mice from the evil Mousy Empire!