Top similar games like STEM Defense:

Build twisting mazes with tetromino blocks and deploy unique towers in this engaging roguelite tower defense game!

Hexguardian is a roguelite, tower defense game where you build your own maps with hexagonal tiles! Build and upgrade towers, recruit armies, learn spells, construct wonders and place hexagonal tiles to create a path to enhance your defenses. With plenty of game modes and talents to unlock!

Rogue Tower is a tower defense game with roguelike elements and a continuously expanding path which you can influence. Unlock, build, upgrade, expand, defend.

Crystal Guardians is a tower defense game with rogue-like elements. Fight of waves and defend the world crystal. Gear up your towers with a powerful combination of items for your strategy. In an ever expanding map, find hidden powers and conquer the enemies.

Rogue Cube Defense is a minimalist roguelite tower defense game with procedurally generated path that you gradually build up. Each run is different as the upgrades you get from leveling up are random. Pick your towers loadout and come up with the best strategy to beat the hordes of enemies.

FrankenStorm is a mazing roguelite tower defense. You are a humble scientist, besieged by endless hordes of angry peasants. Salvage parts to build towers, set traps, acquire upgrades and construct an elaborate maze. Be vigilant or these wily foes will use your own tricks against you!

Tower Knight is a roguelike deck-building & tower defense strategy game. Build your deck to strengthen your position, level up your knight, and win with clever blockades.

Isle of Arrows is a Puzzle Tower Defense game in which you build a fortress in the sky. Place towers, expand the isle, and build your own paths. Can you find the perfect spot for each tile to beat the RNG and defend against waves of invaders?

A Roguelike Tower Defense game set on a user controlled procedurally generated island. Select unique cards and relics that enhance your towers abilities, crafting powerful builds to defend against the growing hordes of enemies.

A tower-defense game with roguelite elements on fully explorable mini planets! Travel the galaxy of Vyrosa, land on planets, and defend your drilling equipment while mining fuel to continue your journey throughout the galaxy!

Stop an endless hoard of crystal-type enemies, with different attributes, from reaching the portal to earth! You can build your own labyrinths, unlock new turrets, upgrade them, unlock abilities, and also gather permanent bonuses.

The Territory of Egg 2 is an unique tower defense indie game. Place Egg Towers, choose evolution branches, combine skills and build defenses. The souls of Heroic Eggs await your awakening! Explore and gather resources in the dark forest, unlock the technology tree, and defeat even stronger enemies!

Tower defense meets deck building in Deck Defense. Defending against the blobs is no easy feat. Will you prioritise fortifying your tower defenses or expanding the map? Can you play your cards right to win?

Crowntakers combines turn-based strategy with RPG elements and takes you at the behest of the crown into a medieval fantasy world full of challenging encounters and epic adventures. With its randomly generated world, Crowntakers offers a varied gaming experience every time you set out to fight evil.

Terrorformer TD is a tower defense roguelite with a procedurally generated map that YOU shape! Assemble a home tower, build your defenses, terraform the map, cast spells, buy upgrades, and unlock new perks with every run. How long can you hold out against the terror?

Island Invasion is an arcade-style tower defence game, where no two playthroughs are the same! Upgrade, path-block, and mine your way to victory, on randomly generated maps and against increasingly difficult enemies.

Defend your valuable chest in randomly generated maps with various towers, traps and obstacles to modify the path that the enemies must follow in "Digs: Prologue", the ultimate rogue-like tower defense game. Experience unique mechanics, upgrade your defenses and face off against challenging enemies

Abyss Protection - dynamic, endless Tower Defense. Fight off the attacks of the inhabitants of the abyss, expand your possessions. Build formidable weapons that will help repulse enemies. Defeat the main evil.

Block Tower TD 2 is a strategic game in the roguelike style with original innovations. Build worlds from blocks, choose random upgrades, each game will be unique.

Outpost brings the perfect mix between survival and roguelite gameplay. Start the game in a randomly generated environment and try to adapt, and make it through as many nights as possible. How long can you survive?

The Territory of Egg is a unique twist on tower defense game. You need to build defense lines with egg warriors to protect the Holy Egg, the core of all eggs. Remember to upgrade your Tech Tree with the resources you've collected and unlock more skills to fight against the evil monsters.

Defend Your Life! Is tower defense set in human body where players are fighting against villain hordes of viruses and bacteria. Levels and units correspond to reality of human anatomy.

A combination of Tower Defense and Rogue-like deckbuilding. Select your heroes, place towers, cast spells, research new technologies and build your deck to defend your castle from enemy forces.

Hold On is a multi-type game including Real-Time Tactics, War-Chess, Tower-Defense for now, and you can build all those types of level.

Crystal Guardians prologue (small slice of the full game) is a tower defense game with rogue-like elements. Fight off waves and defend the base crystal. Gear up your towers with a powerful combination of items for your personal strategy. In a procedural map, find hidden powers and conquer the enemy.

Coral Cove is a relaxing match 3-like underwater game in which you try to build the largest reef without running out of corals to place.

From the developers of Element TD 2 comes a Mazing Tower Defense where you expand the map layout itself. A huge arsenal of towers and a wide variety of enemies clash in a battlefield that shifts on your whims. Engage in single, cooperative, or roguelite gameplay.

A Fantasy based Tower Defence Game. Strategically construct different towers to direct monsters for most damage possible. Additional one shot skills might get you out of that sticky spot. Can you get on the global leaderboards ?

The enemy is approaching. What's your strategy? In this fusion of Tower Defense and Autobattler, optimize the power of your turrets, create strong synergies and wisely choose your bonuses... Or your maluses! Will you be able to defend your city against the hordes of furious monsters?

Defend attacks from enemies from all directions within a limited time. Only by making full use of the differences in each tower and choosing appropriate random rewards can you survive.

“Natti” is a roguelike tower defense game unfolds in the Otherworld of Korean folktales. Place defense towers, collect equipment, and strategically utilize various heroes to defeat all the monsters and protect the Otherworld with “Natti”, goblins in form of animals.

Hallway Defender is a roguelite tower defense where you defend your base from an endless wave of fellow classmates. With over 25 different towers and even more upgrades and effects there are infinite ways to set up your own defenses.

A minimalist high-fantasy maze-building tower defense game that combines rogue-like and deck-building features. Survive for as long as possible, collect magic gems, unlock new skills and towers, prepare your deck, and triumph in the leaderboard!

Everwarder is a 2D roguelite tower defense. Protect the crystal against expanding darkness and enemies that emerge from it. Explore procedurally generated worlds and keep up with constantly rising difficulty by acquiring powerful artifacts, evolve units, progress in upgrade tree and more.

Take on the ultimate tower defense challenge in Digs, a roguelike game where you shape the battlefield, mine resources, and strategize against a variety of enemies. Manage your actions, customize your arsenal with upgrade cards, and explore diverse levels. Can you dig in and emerge victorious?