Top similar games like The Lizard Problem:

A roguelike tower defense where every run reshapes your strategy. Build your team of towers, combine more than 80 artifacts, and explore a pixel-art world while taking on ever tougher challenges and bosses.

A Roguelike Tower Defense in space with missions to conquer. Can you hold against the spreading alien bosses? Build and upgrade towers against the corruption. Choose your technologies and warpspeed your way to victory.

A rogue-like sci-fi Tower Defense strategy game with infinite replayability!

Embark on a quest to mend the Holy Grail and bring harmony to the universe! Gather cards in Explore mode, a peaceful classic RPG, then put them to use in Battle mode, an intense RTS card game, where the fate of the stars is decided.

A medieval Tower Defense x Autobattler Roguelite. Defend your Keep across escalating waves, recruit different unit types, and cast spells from different Schools of Magic. Spend what you earn on a skill tree with over 300 upgrades, and place them on a Decree Bar with many unique modifiers and mults.

Survive as long as possible in Fried Panic! Buy weapons, abilities, and even donut producing machines. Fight through waves of eggs, lemons, chicken drumsticks, and much more, all in a top down pixel art style.

On an alien world, you must defend yourself in this unique base-building tower-defense game. Build a base by placing blocks, turrets and traps in order to survive the hoards of aliens.

Try to survive in infinite asteroid cloud as long as possible in reworked tower defence style. FInd your own playstyle and beat your own records or chillout with original ambient soundtracks. Build, explore, think - everything to create your own colony in this cold space.

Delve for materials, machines and curiosities in this game inspired by Dungeon Keeper and Pikmin.

Dawnhold is a top-down action base-defense game where you gather resources, build up your defenses, and survive relentless enemy waves. Strike back by assaulting enemy strongholds and defeating powerful bosses in a fight to protect the Sunstone.

A roguelike auto-battler defense where luck meets strategy. Spin a 3x3 slot machine to summon units and grow your army by absorbing others. Use Items and Cores to manipulate the odds and survive challenging judgement waves and boss waves. Every spin and every choice counts.

Goofy animals decided to start a battle! Defend your towers with brilliant gold management for sending animal units fight for you. Then collect more units to fill your deck and beat every level on the map!

TEOM is a roguelite strategy game that draws inspiration from the tower defense genre to innovate it through dynamic levels, interactive elements, and high replayability. Follow Aiden and his friends on an unexpected journey through this vibrant world.

Snowbound is a roguelite farming game with tower defense elements. Build your farm, survive the night with a range of defenses, and complete missions to progress deeper into the forest.

Prepare for an epic battle in this captivating tower defense game! Build, defend, and triumph as you strategically place towers, manage resources, and upgrade your arsenal to fend off relentless waves of enemies.

Mana Fortress is a roguelite base defense strategy game. Build up your arsenal of towers and spells to keep your fortress safe from waves of enemies while you gather enough mana and resources to ensure victory.

A tower-defense roguelite. Draft towers, merge three of a kind into something meaner, and pick your route through four acts while the horde quietly learns to counter whatever's working. Ten factions, over 300 tower forms, and a difficulty ladder that does not respect you.

Dive into the whimsical world of Tinker Tactics, a unique blend of roguelike deckbuilding and tower defense. Craft the perfect deck to build the most efficient engines for your toy towers, then fend off waves of malfunctioning toy robots.

A base-building, Roguelike Action/Turn-based Strategy (RATS) game, in a forest invaded by a million Rats. As the powerful Spirit of Vengeance, you must save the adorable Villagers! Explore a randomly generated world, expand your village, and exterminate the Rats!

Gold and Bricks is a small game that mixes elements of city builder, roguelite, strategy and tower defense. Plan the layout, manage your economy and invest your gold in defensive towers to protect yourself from the hordes of enemies invading your village.

Raise a fallen keep by day, and hold it through the dark. Villagers with names and tempers fell timber and work the fields — then take up spears when night comes. A dark fantasy settlement-builder defense game.

Plant towers, hold the Nexus. A pixel-art tower defense where population caps how wide you can build, gold and mana decide what you build with. Draft augments as you level, spend gems on a permanent power-up tree, and find out how long your walls hold.

Defend your turf against endless waves of grinning enemies! Pick from 6 unique smiley classes with their own abilities, build and upgrade turrets across multiple lanes, and take down ever-tougher bosses – a colorful tower-defense hybrid built for replayability.

Cluckmech Oasis, a top-down shooting Roguelike tower defense game. Play as the Warcluck and lead your team of animal heroes in a fight for survival. Collect, build and upgrade defenses, and engage in intense battle against waves of plant enemies.

Ready for some chaos? Command 5 characters in this Roguelite Tower Defense! Build your dream team, crush enemies, and have a blast with adorable pixel art!

A real-time line-battle roguelite. Spend rations to summon swordsmen, shields, archers and cavalry onto a single front, then break the enemy base. Pick relics and promotions at every fork to build a different army each run. Three commanders, three ultimates.

Ice Fighter is a fast-paced Tower Defense-like game where you battle enemies, scavenge for resources, manage upgrades, and build defenses. Melt enemies during the night and gather resources during the day.

Fight your way through a large variety of rooms, enemies, and bosses. Collect unique items each floor, developing your stats and creating interesting item combos with terrifyingly powerful synergies! Play to enjoy the rush, or piece together the story through the various endings and hidden messages!

Fend off endless hordes of enemies in this roguelite tower defense. Build your own path to maximize carnage. Unleash devastating hero abilities to turn the tide of battle. Upgrade your arsenal with dozens of new towers and heroes to keep your castle from oblivion. Survive and become dauntless.

Heart of Machine blends top-down tower defense with light roguelite elements. Face an evolving mechanical swarm thousands strong, tailor defenses, upgrade towers with chips, and use real-time support weapons to turn the tide. Build an unbreakable line and save the core from destruction.

Survive waves of enemies raining bullets on you with the help of your trusty Automatic Turret Machines (ATMs) while you focus on more important priorities: making bank. It's equal parts bullet hell, tower defense, incremental game, and rogue-lite. Coming out later this year in 2024!

‘Blood Moon: Last Stand’ is an action-strategy game set in Xianxia, blending wave defense, real-time control, and roguelike deck-building. Command up to three cultivators, forge unique builds, and withstand relentless hordes and bosses. Survive seven days to overturn fate.

Command your king in a frantic real-time tower defense roguelite. Play cards to summon autonomous troops, construct buildings, and set traps as you scramble to defend your castle against escalating enemy hordes.

Defend your town against relentless enemy waves in this top-down action game that combines real-time combat, strategic town upgrades, and tower defense. Recruit powerful soldiers, strengthen your defenses, and survive until the final battle.

Upgrade your engine’s arsenal in this bullet hell, tower defense roguelite featuring the most heavily armored locomotive in existence. Engineer and command the Ironfront Express in a unique take on lane defense where you upgrade with specialized turrets, drones, and tactical abilities.

A cute, challenging roguelite tower defense. A campaign across 4 planets, 14 unique towers, a map editor, endless mode and a massive skill tree for gameplay that's all your own.