Top similar games like The Lizard Problem:

A Roguelike Tower Defense in space with missions to conquer. Can you hold against the spreading alien bosses? Build and upgrade towers against the corruption. Choose your technologies and warpspeed your way to victory.

A rogue-like sci-fi Tower Defense strategy game with infinite replayability!

Gattai TD is a roguelike, mazing tower defense in which you merge towers and gain ancient wonders to hold back waves of cursed keepsakes.

Survive as long as possible in Fried Panic! Buy weapons, abilities, and even donut producing machines. Fight through waves of eggs, lemons, chicken drumsticks, and much more, all in a top down pixel art style.

Try to survive in infinite asteroid cloud as long as possible in reworked tower defence style. FInd your own playstyle and beat your own records or chillout with original ambient soundtracks. Build, explore, think - everything to create your own colony in this cold space.

Delve for materials, machines and curiosities in this game inspired by Dungeon Keeper and Pikmin.

Snowbound is a roguelite farming game with tower defense elements. Build your farm, survive the night with a range of defenses, and complete missions to progress deeper into the forest.

Goofy animals decided to start a battle! Defend your towers with brilliant gold management for sending animal units fight for you. Then collect more units to fill your deck and beat every level on the map!

TEOM is a roguelite strategy game that draws inspiration from the tower defense genre to innovate it through dynamic levels, interactive elements, and high replayability. Follow Aiden and his friends on an unexpected journey through this vibrant world.

Mana Fortress is a roguelite base defense strategy game. Build up your arsenal of towers and spells to keep your fortress safe from waves of enemies while you gather enough mana and resources to ensure victory.

Guide your familiar through the stars! Space Witch is a self-paced 2D top-down rogue-like collectathon, designed to align your mind, body, and soul.

Prepare for an epic battle in this captivating tower defense game! Build, defend, and triumph as you strategically place towers, manage resources, and upgrade your arsenal to fend off relentless waves of enemies.

Dive into the whimsical world of Tinker Tactics, a unique blend of roguelike deckbuilding and tower defense. Craft the perfect deck to build the most efficient engines for your toy towers, then fend off waves of malfunctioning toy robots.

A base-building, Roguelike Action/Turn-based Strategy (RATS) game, in a forest invaded by a million Rats. As the powerful Spirit of Vengeance, you must save the adorable Villagers! Explore a randomly generated world, expand your village, and exterminate the Rats!

Gold and Bricks is a small game that mixes elements of city builder, roguelite, strategy and tower defense. Plan the layout, manage your economy and invest your gold in defensive towers to protect yourself from the hordes of enemies invading your village.

Ready for some chaos? Command 5 characters in this Roguelite Tower Defense! Build your dream team, crush enemies, and have a blast with adorable pixel art!

Cluckmech Oasis, a top-down shooting Roguelike tower defense game. Play as the Warcluck and lead your team of animal heroes in a fight for survival. Collect, build and upgrade defenses, and engage in intense battle against waves of plant enemies.

Fend off endless hordes of enemies in this roguelite tower defense. Build your own path to maximize carnage. Unleash devastating hero abilities to turn the tide of battle. Upgrade your arsenal with dozens of new towers and heroes to keep your castle from oblivion. Survive and become dauntless.

Ice Fighter is a fast-paced Tower Defense-like game where you battle enemies, scavenge for resources, manage upgrades, and build defenses. Melt enemies during the night and gather resources during the day.

Fight your way through a large variety of rooms, enemies, and bosses. Collect unique items each floor, developing your stats and creating interesting item combos with terrifyingly powerful synergies! Play to enjoy the rush, or piece together the story through the various endings and hidden messages!

Survive waves of enemies raining bullets on you with the help of your trusty Automatic Turret Machines (ATMs) while you focus on more important priorities: making bank. It's equal parts bullet hell, tower defense, incremental game, and rogue-lite. Coming out later this year in 2024!

SUPRACORE is a roguelike base building game. Build your base, upgrade it and defend against ongoing waves of enemies to gather more resources and expand your Core!

OBA DOBA is a Roguelike RTS/Tower Defense that is fast, funny, and frantic. Defend your base with towers and fighters while managing your resources and upgrades. Build up your arsenal of structures, abilities, and passives to defeat the evils that await. Build, rebuild, and survive! (hopefully)

Classic tower defense meets roguelike adventure where you control the hero! Dive into procedurally generated levels filled with unique waves of enemies. Create powerful synergies with a variety of game-changing skills, relics, weapons, and traits to defend your kingdom. Every run is a new challenge!

A living ant tower defense, upgrade abilities to increase competitiveness. Combine different ant species to form an aerial defense and kamikaze attacks. Deploy ants to collect honey. Breed ants to expand your territory and compete against red fire ants to save the natural environment of the island.

As the kingdom's most promising pioneer, embark on a legendary journey to tame the frontier! Build thriving towns across various landscapes, fending off waves of diverse enemies until you establish a firm foothold and have explored everything the eye can see!

Little Kingdom RTS is an indie real-time strategy game set in a medieval fantasy world. Gather resources, build settlements, raise walls, and grow your small kingdom. Command an army of knights, archers, and mages to fight off rival kingdoms, orcs, and undead.

A real-time strategy game combining deck-building mechanics. Summon soldiers to control a 3x3 battlefield and deal damage by completing lines using Tic-Tac-Toe rules. Make quick decisions and build your deck strategically to protect the kingdom’s resources.

The adventure in the mysterious world of the Wall continues! Pilot your robospider into its depths, uncover lost artifacts and technologies, upgrade your exosuit and spider, and battle the horrors lurking in the dark. Unravel the mysteries buried in the depths of the Wall!

A valiant knight embarks on a perilous quest to find a mystical portal that will lead him back to his homeland. Clad in gleaming armor and wielding his trusted fork, he traverses treacherous landscapes only to be haunted by none other than...cows.

TINAD is a unique tower defense game where you defend your retirement home from overeager heroes. Play as the dungeon itself. Deploy traps, summon minions, and prove you’re just trying to enjoy your golden years in peace against heroes who can’t read the sign and assume every dungeon is evil.

Raise your favorite characters and have them ready to fight in the next run! Command beautiful girls to defend the castle and princess A non-reset roguelite × tower defense

Defend your castle, mine for minerals, and level up your wizarding powers in this thrilling action-roguelike game. Grab your wand and prepare to fight off magical foes in this epic battle for survival!

Combination of roguelike and strategy in one side view game. Defend yourself against constantly attacking Elms while researching procedural research branches. Destroy the enemy or lose

Endless tower defense with roguelike cards and mining. Build between waves, unlock legendary upgrades, and face escalating enemies and bosses.

Combine chemicals, prepare potions, and battle hordes of mythical monsters in this action-packed, chemistry-themed roguelike. You'll fight your way through a procedurally-generated science lab, exploding endless enemies and solving various puzzles, all to earn coins and upgrade your equipment.