Top similar games like Patient Zero: Plague Idle:

SynthetiCell BioClicker is an Idle incremental simulator where you bring to life a colony of synthetic automaton cells. Inspired by the classic 'Game of Life' by mathematician John Horton Conway (1970) about the evolution of an organism. Can you guide your colony to prosperity?

From 0 to Hero investing simulation game. Start as a dead end job worker and work your way to financial freedom. Supports both minmaxing and relaxing playstyles.

These bees are hard workers and terrible thinkers, so you do the thinking. In this programming game you connect nodes into programs, and the colony does exactly what you said. Not always what you meant. Start with one clueless bee. End with a hive that runs itself. The Queen will still want more.

Grow food. Smash it into bites. Feed Fred. An active incremental game about one very hungry creature. Discover stranger foods, cook better meals, and hire Friends to keep food coming from every location. Recycle Fred's waste into fertilizer and watch his weight climb.

Manage a colony of living cells in a strategy game built from real biology. Build phospholipid membranes, place organelles, import nutrients, fight viruses, detect cancer, and divide your cells to grow. No tutorials. No lectures. Learn by keeping the cell alive.

A relaxing idle city-builder where a single hut grows into a sprawl of millions. Build production chains, let your civilisation expand while you're away, and Ascend to push the whole world up an order of magnitude.

Do you need more RAM? Of course you do. Everybody does. Get RAM Downloader and improve your quality of life. The clicker / idler, that gets you all the RAM you need. It's easy. You click Download. RAM increases. You live a happier life.

A condensed incremental experience, where you build a colony to collect and merge bigger and bigger fruits. Combine game-changing technologies and special upgrades to find the best synergies and take your cash flow to another dimension.

Apiary in Flow is an incremental game with automation elements where you place bees inside a hive to build efficient honey-gathering chains. Unlock new bee types and spend your harvest on permanent skill tree upgrades!

Build a living ant colony that can stay on your desktop while you work. Hatch unusual ants, place nest and food rooms, collect coins, and expand from a glass habitat into drawers, pipes, walls, roots, and the forgotten depths below.

Idle Cosmos Clicker is a space-themed idle simulation where you grow the universe from asteroids to black holes. Produce, automate, and evolve resources while unlocking planets, stars, and galaxies. A relaxing yet deep incremental experience with endless progression.

An idle game where you gather resources and grow your city. Sit back and watch your city expand!

A cute incremental clicker where you bonk bugs for profit. Earn money, unlock upgrades, acquire powerful skills, and recruit helpers to automate the bonking until you’re truly unstoppable. Satisfying and Relaxing!

Giant Horse Feeding is a silly alien colony simulator where you feed a horse & collect its droppings to build an alien empire. Automate production, unlock bizarre technologies, and create an endless recycling loop where horse droppings become the foundation of your civilization.

Turn a bankrupt recycling yard into a smooth-running operation in this relaxing incremental management game. Open bags and sort waste by hand, hire a crew, install processing machines, and automate the journey from truck delivery to valuable recycled goods.

Slay giant bosses and turn the hollow wasteland into the almighty kingdom! Endlessly rewarding incremental game where you collect fountains of rare loot, unleash crazy combos and watch the monsters fall under your knees. Boss Rush that keeps on going when you're gone!

An incremental game about flipping bottles, unlocking and upgrading unique abilities, and turning simple bottle flips into increasingly satisfying moments.

Build a quiet fishing harbor in an atmospheric idle strategy game. Send your fleet to sea, sell the catch, expand warehouses and buildings, collect captain and ship cards, and sail from a peaceful bay toward dangerous depths.

Run an office of parody AI models through the night. Work jobs by hand, buy models like Llamba and Clawed into desks, and keep them cool with fans, a battery and solar panels. Pivot for Vision, open five offices on a city map and take the company public.

Goblin Smasher is an addictive idle/incremental game where you crush endless hordes of goblins. Sweep your mouse to blast goblins, explore a massive skill tree, equip your heroes, collect relics, and become an unstoppable force!

Click, topple and profit! Knock over tiny wandering Humans, hire Animals to cause chaos, collect mountains of coins and grow your ridiculous empire. Unlock powerful Rebirth upgrades, defeat Bosses and turn a peaceful board into a glorious mess of falling people.

An incremental tycoon about getting rich in a crooked city. Play as a thief, a dirty cop, a 9–5 worker or a suburban teen, and climb from nobody to the person Port Vesper can't function without. Every run, the city you left behind has changed.

Stolen Legacy!! Click, hustle, invest. From nobody to legend!

Pirate Treasure Hunt is a short incremental treasure hunting game. Explore islands, uncover rare treasures and ancient artifacts, upgrade your expedition and become the richest pirate on the seas.

Incremental clicker/idle and narrative game where you crush empty cans, sell the aluminum, upgrade your equipment, and buy factories and automatic presses to automate the process. Discover what happened to your wife and son as you try to save Aluminum City from an evil villain.

The company is falling apart, and you're both the HR cleaning up the mess and the CEO profiting from it. Optimize people, rebuild workflows, automate production, and watch the numbers go up.

Build a cosmic energy empire in this colorful incremental sci-fi game. Click, automate production, unlock technologies, explore distant planets, collect artifacts, raise cosmic pets, and ascend to unlock permanent upgrades.

A chill idle game in the corner of your screen. Popups spawn. Close them. Earn money. Buy upgrades. Repeat.

Start with one donut. End with a multidimensional bakery empire. Click, automate, expand, unlock the Research Lab, run a Storefront, and break through to the Donut Hole. A layered idle game that keeps unfolding new systems until your mouse screams for mercy.

Billion Bounces is a short incremental game with bouncing balls, bumpers, and one goal: earn coins, buy upgrades, and watch the economy slowly fall apart.

Start with a small plot in the middle of a forest and a few wind turbines. Sell power to the city, buy the land next door, and work your way from solar to nuclear and on to fusion. Your plants keep running even when the game is closed.

A Minesweeper-inspired incremental where every cell you dig pays. Run short shifts, buy upgrades between them, and work your way up a seven-floor company tower — glaciers, volcanoes, deep space, a casino on top. Mines? That's what insurance is for.

Incredig is a short sci-fi incremental mining game about digging far too deep. Break rock pixel by pixel, haul ore back to your Rig, automate the mine with swarms of drones, and keep pushing downward. Something beneath the surface is beating.

Start with a single sickle and a tiny field. Cut and sell grass, automate your workforce, optimize supply chains, and build a sprawling incremental empire.

Weedcraft Inc explores the business of producing, breeding and selling weed in America, delving deep into the financial, political and cultural aspects of the country's complex relationship with this troublesome and promising plant.

An idle strategy game about the trade beneath a forest. Route Carbon, Phosphorus and Water through a mycorrhizal network, sporulate to begin again stronger, and press down through deep time until the forest becomes one organism.