Top similar games like Patient Zero Pandemiс Simulator:

Make Your Kingdom is a city-building game where you need to survive, revive and develop a settlement. You are a founder of a new settlement! Choose the best way to develop and achieve your goals. Find a way to win the people's favor by satisfying their needs.

Craft bio-weapons, master lethal science, and unleash global annihilation. Experiment. Fail. Adapt. Evolve. Repeat until humankind falls.

If you have ever thought of becoming a doctor – here is your chance! Arm yourself in a stethoscope and do a ward round to keep up to date with your patients’ condition. They may complain and question your authority but remember – you’re the doctor!

Design, build and control your own space station. Mission command and control is in your hands and only careful planning and vigilant supervision will keep your crew and space station safe.

Kingdom is a 2D sidescrolling strategy/resource management hybrid with a minimalist feel wrapped in a beautiful, modern pixel art aesthetic.

In the event of a global pandemic, would your first priority be preserving lives or saving the economy?

You have awoken as a small god. As you accumulate the faith and souls of your followers, you will learn incredible new abilities. Protect, guide your people and smite any threats that may arise. The fate of your world is in your hands.

What if you had it in your power to rid the world of disease, to improve the lives of millions, to ease suffering and cure the sick… and earn a tidy profit? As the head of your own Pharmaceutical Conglomerate you have this power resting in your hands. Will you use it for good?

Through an "accident" seafarers arrive on an island where they have to fight for their survival. Help them by building and managing a tree house for them.

Design your own skyscraper with more than 100 Floors. Rent offices, apartments or shops and build a financially lucrative skyscraper. Build cinemas, bars or a theater to satisfy your visitors and create an effective transport system with elevators and stairs.

This is a free version of Oxygen, featuring the first 50 game-days. Build your city around the Oxygen Center and ensure your people's survival in a post-apocalyptic future, threatened by crack explosions, deadly winds, droughts and frosts. Lead your people and keep the Oxygen Center running!

Guide tiny planets back into harmony in Spherical Symphony. Balance each world’s living systems, recruit cozy catfolk helpers, befriend cosmic sea creatures, trade between worlds, repel threats, and awaken the sleeping sun at the heart of it all.

Explore a mysterious planet, harvest and refine resources, discover new technology, craft machines, and set up automated factories.

CloudDwellers is a 2D simulation and city-building game set in a world of scattered floating islands. Guide your settlers to harness technology, optimize production, and transform fragmented skies into a thriving, beautifully crafted aerial haven.

Casual town builder that takes place on floating islands in a fantasy world. Grow your town and manage your resources in this challenging builder.

Build, renovate and manage your hotel to keep your guests happy. Increase your star rating, but be careful - unhappy guests leave bad reviews and you don't want to lose your hotel!

Diluvian Winds is a management game set in a small hamlet at the foot of a lighthouse. Welcome weary travelers and help each other to try and survive the unpredictable weather. Grow your hamlet on land by discovering new rooms.

A prologue to a survival strategy game on the Moon. Contact with Earth is lost, help isn’t coming, and the Sun burns everything in its path. Control your mobile base, gather resources, make tough moral choices—and run into the shadows.

Foundations is a free version of Masterplan Tycoon, a minimalist resource management sim. The world is your playground: start with simple production lines for basic needs and evolve into a production powerhouse in an elegant and stress-free setting

Weedcraft Inc explores the business of producing, breeding and selling weed in America, delving deep into the financial, political and cultural aspects of the country's complex relationship with this troublesome and promising plant.

Project Aura is a micro management game where you lead a Colony of Climate Disaster Survivors. You have been assigned the mission to build an habitat capable of survival in this new unknown world.

Build a magical village full of life and wonder, while taking care of the villagers who live there. Expand your territories, add unique buildings and decorations. Along the way, discover hidden spirits who will help your town grow and flourish.

Block Factory is a relaxing and creative building game where you craft delightful 3D figurines from blocks. Shape your designs and build flowing production lines in a peaceful factory world.

Discover a post-apocalyptic world Collect resources and manage people Build your colony on the remains of an oil tanker Prepare supplies and vehicles for a dangerous expedition. Complete challenging tasks from the council of elders

Guide pioneering settlers among Venusian clouds in this space colonisation city builder. Grow food, collect energy, mine resources, balance buoyancy and weight to stay afloat in the treacherous Venusian atmosphere, and build a self-sufficient colony while navigating storms and acidic clouds.

Build an intricate prison, hire the best staff, and pamper your prisoners to create the perfect rehabilitation facility in Prison Tycoon: Under New Management

Become a one-man renovation company and take care of the reconstruction of a ruined hospital! Save a neglected facility and create a fully functional emergency complex. The entire process of cleaning, planning, repairing, and arranging is on your side. Build a dream clinic in the Hospital Renovator!

Maia is a colony building game set in the not-so-distant future. Your colonists make planetfall on a hostile world and you must ensure their survival and their safety, constructing their off-world habitat from almost nothing and sheltering them from a dangerous, often deadly environment.

Blockville is a relaxing, funny, stylized city building simulation game where you can build a city inspired by the toys you all used to play with as a child. A mix of modern day city building sim with a comedy twist. Now you have an excuse to play again as an adult in this stylized city sim.

You command a drilling train, leading a dwarf clan through the underground depths toward the planetary core. Manage the crew, complete expeditions, gather resources, upgrade gear, and make tough choices to reach the abandoned city and bring your people back home.

Shape worlds with your godly titans. Make symbiotic ecosystems and inspire humanity with your creations. Their achievements unlock new possibilities. Make different planets for different human spirits, and fill the universe with life!

Build and automate your way from a comet miner to an entertainment mogul in this isometric tycoon game. Harvest resources and buy bigger comets to keep more peeps happy, alive and profitable.

Service Please: First Dinner! Build, manage, and expand your own restaurant! Control everything from the kitchen to service, from decoration to automation. Satisfy your customers, increase your prestige, manage your staff, and turn your restaurant into an efficiency driven service machine!

Build, manage and optimise intergalactic hospitals! Recruit staff to satisfy the whims of various alien species, and cure their bizarre illnesses - for money! Save the (literal) Galaxy in story mode, or head into sandbox to design the hospital of your dreams.

Crafting Town Is : A Crafting game with Simulation&Building where you can Craft and Develop your Village, Source Management and Quests.