Top similar games like Post Apocalypse Microbe Lab:

Idlequarium is a casual simulation game where you raise adorable little fish to earn coins, purchase decorations, and build a fully customized aquarium.The game sits anywhere on your desktop, letting you interact with your live aquarium during work or study breaks.

Watch a tiny diver explore the ocean in the corner of your screen. Collect sea creatures, upgrade equipment, and unlock new diving spots.

"Skytopia" is a charming pixel-style fishing simulation idle game. Decorate a beautiful sky island at the base of your desktop, immerse yourself in a relaxing fishing lifestyle, and hatch and nurture a variety of adorable animals on the island.

Cozy Littlequarium is a relaxing aquarium simulator that sits at the bottom of your screen! Take care, breed them, collect and decorate!

A chill clicker-idle stars hunting and constellations creation game that sits in the corner of your screen. Feel free to daydream while you are working or doing something else.

A cozy idle fishing game where you play as an adorable alligator angler. Designed to run in the corner of your screen, it's the perfect companion for work or study—featuring rich animations that make every moment feel like watching a charming short film.

Desktop Fishing is a cozy idle game that sits in the corner of your screen. Go about your usual desk work (or don't) while your frog buddy catches fish, discovers new outfits, and unlocks fishing spots.

Creature Evolution is a simple game about merging little creatures and seeing what they turn into. You start with a few small critters, and by combining them, they slowly change into new and sometimes unexpected forms. The more you merge, the stranger and bigger they grow.

A chill idle-fishing desktop toy in the corner of your screen. Buy upgrades, catch rare fish, and customize your avatar at your own pace!

"Launch the hook to the sky! Capture the unknown!"Use a specially designed anti-gravity fishing rod to fish for strange flying creatures in the mutated clouds, establish a new era of Earth's ecological atlas, and explore the oddities of civilization in the joy of picking up trash.

A relaxing idle fishing game that waits for you at the bottom of your screen. CATCH fish, BUY upgrades, COMPLETE your collection, and DISPLAY them in your aquarium.

An idle desktop pet game where pixel RPG heroes patrol the bottom of your screen, collect loot, and level up while you work.

Chillquarium is a cozy and relaxing idle game. Buy fish and raise them in real time, then sell them to turn a profit! Customize your aquarium as you progress from a simple starter tank to your dream setup by filling your collection with rare exotic fish and ultra-rare color variants!

Collect over 100 stylish little pets on your desktop! They can freely move along the bottom of your screen, or live in the little houses you've carefully decorated for them. Hmm... or perhaps send them on adventures to earn treats?

This is a group of cute little fish swimming leisurely at the bottom of the screen while you work. The fish swim, grow and earn stars for you. Use them to buy other cute little fish until the bottom of the screen becomes a colorful ocean world! Start a leisure desktop fish farming journey!

Hatch mystery eggs, watch fish grow to reveal their hidden rarity, and collect the rarest ones in a cozy aquarium you can relax with in the background.

Decorate your own aquariums and care for a variety of fish in Fishlets, a cozy fish-collecting sim! Feed, breed, sell, and collect fish and aquatic critters in the virtual tanks mode. Drop into Adventure mode and progress through 7 unique levels, unlocking even more fish while fending off threats!

Little Aquarium is a relaxing idle game where you grow your own underwater world. Collect rare fish, discover vibrant color variants, and decorate your dream tank!

《Fluffy Kitchen Saga》A restaurant simulation game located at the bottom of your computer screen, where both staff and customers are fluffy little animals! They’ll keep you company while you work/study. Let’s run a restaurant full of fluffiness!

"Internet Fisherman" is an idle fishing game with Steam Community trading, where you can obtain rare fish every 2 hours and add them to your Steam inventory. Players can feed fish to cats to increase affection, and will appear on the affection leaderboard to compete with other players.

Here’s a cute, chubby black cat. All it wants to do is quietly go fishing. “Right in the corner of your desktop!” Collect fish to fill up the cat’s encyclopedia, earn money, and dress it up in adorable outfits!

Mango’s Fisharium is a short incremental game about catching unique fishes and displaying them in the Fish Aquarium. Designed to be completed in around 4 hours.

Brewbie’s Alchemy Desk is a cozy idle simulation about potions and tiny magical helpers. On your enchanted desk, you’ll meet the adorable Brewbies—little spirits who happily run your workshop while you relax. Decorate your desk however you like and enjoy a slow, healing moment of magic.

"My Aquarium" runs at the bottom of the screen while you are doing other things, making it an idle aquarium simulator you can enjoy comfortably.

In Fantasy Idle Dungeon, hatch and capture rare Jenin, awaken their legendary skills and talents, and experience the joy of leveling up, evolving, and fusing them. Freely customize your gear, assemble an unbeatable adventure team, and claim glorious victories with effortless idle gameplay!

Cozy Island Idle is a chill fishing idle game where you catch all sort of fantasy fishes to showcase them in an Aquarium to sell them to turn a profit and customize your aquarium and island.

Welcome to Fish to Dish: Idle Sushi! This is a relaxing and enjoyable idle fishing game that can sit at the bottom or any corner of your screen, allowing you to enjoy a leisurely sea fishing time in your busy life.

Cast n Chill is a relaxing fishing game where you explore serene lakes, rivers, and oceans. Catch rare fish, upgrade your gear and reel in legendary catches - all with your loyal companion by your side.

Chonkers is a cozy and relaxing idle game. Adopt the cutest fur balls and watch them ramp up the chonk scale as you play with them. Find them a new family. They’ll pay A LOT for your hefty chonker! Complete your collection by finding all the breeds and the rarest space cats!

A relaxing and humorous idle god simulator that stays at the bottom of your screen or on a second monitor while you do other things. With physics-based dragging interactions, it feels just like playing with desk toys.

Relax in a calm idle incremental aquarium. Buy and feed fish that grow in real time. Sell fish to buy more fry and discover rarer species. Build your oasis: unlock and place decorations, and enjoy fish interacting with them. Your world keeps earning even while you're away

A creature collection game that sits at the bottom of your screen & fits easily into your routine. Whether you're working, studying, or relaxing, Whimside is always ready to offer you a cozy escape. Capture rare creatures, create new species & decorate your whimsical space!