Top similar games like Post Apocalypse Microbe Lab:

Idlequarium is a casual simulation game where you raise adorable little fish to earn coins, purchase decorations, and build a fully customized aquarium.The game sits anywhere on your desktop, letting you interact with your live aquarium during work or study breaks.

Watch a tiny diver explore the ocean in the corner of your screen. Collect sea creatures, upgrade equipment, and unlock new diving spots.

"Skytopia" is a charming pixel-style fishing simulation idle game. Decorate a beautiful sky island at the base of your desktop, immerse yourself in a relaxing fishing lifestyle, and hatch and nurture a variety of adorable animals on the island.

"Launch the hook to the sky! Capture the unknown!"Use a specially designed anti-gravity fishing rod to fish for strange flying creatures in the mutated clouds, establish a new era of Earth's ecological atlas, and explore the oddities of civilization in the joy of picking up trash.

Little Aquarium is a relaxing idle game where you grow your own underwater world. Collect rare fish, discover vibrant color variants, and decorate your dream tank!

A chill idle-fishing desktop toy in the corner of your screen. Buy upgrades, catch rare fish, and customize your avatar at your own pace!

Chillquarium is a cozy and relaxing idle game. Buy fish and raise them in real time, then sell them to turn a profit! Customize your aquarium as you progress from a simple starter tank to your dream setup by filling your collection with rare exotic fish and ultra-rare color variants!

Welcome to Fish to Dish: Idle Sushi! This is a relaxing and enjoyable idle fishing game that can sit at the bottom or any corner of your screen, allowing you to enjoy a leisurely sea fishing time in your busy life.

An idle desktop pet game where pixel RPG heroes patrol the bottom of your screen, collect loot, and level up while you work.

Joyquarium is a relaxing casual fish-raising game. Buy various cute fry and sell them at a high price after they grow up. With the money you earn, you can purchase aquatic plants, driftwood, scenery stone, etc. to decorate your tank (you can freely adjust the color, size, and position).

An aquarium sim you can keep anywhere on your screen while you do other things. Buy endless upgrades, apply trait modifiers, and complete your collection of rare, epic and legendary fish! Buy today or give a gift to someone!

Decorate your own aquariums and care for a variety of fish in Fishlets, a cozy fish-collecting sim! Feed, breed, sell, and collect fish and aquatic critters in the virtual tanks mode. Drop into Adventure mode and progress through 7 unique levels, unlocking even more fish while fending off threats!

A chill clicker-idle stars hunting and constellations creation game that sits in the corner of your screen. Feel free to daydream while you are working or doing something else.

Desktop Fishing is a cozy idle game that sits in the corner of your screen. Go about your usual desk work (or don't) while your frog buddy catches fish, discovers new outfits, and unlocks fishing spots.

Expand your farm, get more animals, earn more coins, and start all over again. The first clicker with a fishing mini‑game!

Cozy Littlequarium is a relaxing aquarium simulator that sits at the bottom of your screen! Take care, breed them, collect and decorate!

A relaxing idle game about fishing. Discover dozens of fishes and treasures! Spend your resources on growing your operation and unlocking new varieties of underground life! Achieve goals, buy skills, and mutate rare fish to improve your profits!

This is a group of cute little fish swimming leisurely at the bottom of the screen while you work. The fish swim, grow and earn stars for you. Use them to buy other cute little fish until the bottom of the screen becomes a colorful ocean world! Start a leisure desktop fish farming journey!

A relaxing and humorous idle god simulator that stays at the bottom of your screen or on a second monitor while you do other things. With physics-based dragging interactions, it feels just like playing with desk toys.

"My Aquarium" runs at the bottom of the screen while you are doing other things, making it an idle aquarium simulator you can enjoy comfortably.

Catio Simulator is a casual clicker game in which you decorate a catio to attract cats. Pet your cats to get them ready for adoption, collect adoption fees, and buy new decorations and petting abilities!

SynthetiCell BioClicker is an Idle incremental simulator where you bring to life a colony of synthetic automaton cells. Inspired by the classic 'Game of Life' by mathematician John Horton Conway (1970) about the evolution of an organism. Can you guide your colony to prosperity?

A relaxing idle fishing game that waits for you at the bottom of your screen. CATCH fish, BUY upgrades, COMPLETE your collection, and DISPLAY them in your aquarium.

Mango’s Fisharium is a short incremental game about catching unique fishes and displaying them in the Fish Aquarium. Designed to be completed in around 4 hours.

Brewbie’s Alchemy Desk is a cozy idle simulation about potions and tiny magical helpers. On your enchanted desk, you’ll meet the adorable Brewbies—little spirits who happily run your workshop while you relax. Decorate your desk however you like and enjoy a slow, healing moment of magic.

Gachamon is a cozy idle clicker where gacha meets multitasking. Collect creatures, earn coins, and climb the ranks — all from the bottom of your screen!

Here’s a cute, chubby black cat. All it wants to do is quietly go fishing. “Right in the corner of your desktop!” Collect fish to fill up the cat’s encyclopedia, earn money, and dress it up in adorable outfits!

Summon and study witches’ familiars in this charming creature collection game. Gather dragons, spirits and more in your quest to complete your magical grimoire. Watch them enchant your screen without intruding while you work, study or relax. With over 100 variations there’s a favourite for everyone!

A cozy idle fishing game where you play as an adorable alligator angler. Designed to run in the corner of your screen, it's the perfect companion for work or study—featuring rich animations that make every moment feel like watching a charming short film.

Misty's Idle Fishing is a relaxing idle fishing game that sits on your desktop! Help Misty upgrade her equipment, customise her boat, and discover new islands, so she can catch and research all sorts of fish while you are busy with other things!

神圣世界是一个可以放置的自动化游戏，拥有挂机功能，采用回合制战斗的设计了战斗环节。你会进行许多场战斗，在这个过程中遇到新的伙伴，打造新的装备，最终收获一支强大的队伍，所向披靡。

Start with a broken phone... and follow Mercie, a lazy witch, as she juggles fairies, weird upgrades and a cauldron that turns anything into everything! Brew all kinds of stuff and embrace the cozy chaos in this offbeat incremental idle game

Grow fish with a gachapon twist in this bite-sized idler! Feed, nurture, and watch as fisher people reel in mature catches, earning money to upgrade things like feeding, growth, and fishing speeds for even faster profits.

Beastkeepers is your creature taming adventure at the bottom of the screen. Breed and train powerful creatures, battle enemies, and earn coins. Use them to unlock new creatures, upgrades, and decorations. Grow stronger and progress endlessly!