Top similar games like Post Apocalypse Microbe Lab:

Idlequarium is a casual simulation game where you raise adorable little fish to earn coins, purchase decorations, and build a fully customized aquarium.The game sits anywhere on your desktop, letting you interact with your live aquarium during work or study breaks.

"Meet your new hardworking desk companion! Cozy Desktop Pal mines, fishes, and farms while you focus on your work. Help your pal survive by managing their needs, trade resources in the market, and use skill points to transform a tiny worker into a master adventurer."

A relaxing mini aquarium that stays on your desktop corner while you do other stuff — collect fish, upgrade tanks, and enjoy a cozy idle experience.

A cozy idle fishing game where you play as an adorable alligator angler. Designed to run in the corner of your screen, it's the perfect companion for work or study—featuring rich animations that make every moment feel like watching a charming short film.

"Launch the hook to the sky! Capture the unknown!"Use a specially designed anti-gravity fishing rod to fish for strange flying creatures in the mutated clouds, establish a new era of Earth's ecological atlas, and explore the oddities of civilization in the joy of picking up trash.

Welcome To The Crater! It's been 100 years of drought, but water has returned and with it a flourishing of new life to find! Discover new creatures, customize your aquarium to perfection, and collect them all! Fish right on your desktop with passthrough or enjoy the scenic views of The Crater!

Collect over 100 stylish little pets on your desktop! They can freely move along the bottom of your screen, or live in the little houses you've carefully decorated for them. Hmm... or perhaps send them on adventures to earn treats?

A chill, tamagotchi-like idle creature game in the corner of your screen. Raise creatures, unlock 100+ evolutions, and freely customize your room at your own pace!

Watch a tiny diver explore the ocean in the corner of your screen. Collect sea creatures, upgrade equipment, and unlock new diving spots.

Little Aquarium is a relaxing idle game where you grow your own underwater world. Collect rare fish, discover vibrant color variants, and decorate your dream tank!

Build a living pond where every fish has a unique genetic code. Breed for rare traits, balance oxygen and hunger, unlock new species, and watch your ecosystem compose its own soundtrack in real time. Part sim, part idle game, part science experiment gone beautifully wrong.

A one-button game where failure is progress, inaction is a choice, and luck is never entirely fair. Discover every egg, stage, secret, and animal while putting your fortune to the test. It’s a piece of cakegg!

Cozy Littlequarium is a relaxing aquarium simulator that sits at the bottom of your screen! Take care, breed them, collect and decorate!

Pilot a submarine into the deep. Kill fish, harvest PSI energy, and defeat 25 bosses across 5 ocean zones. Ascend, transcend, and unlock the Void. A deep-sea idle dungeon crawler with 3 prestige layers, 36 forgeable artifacts, procedural audio, and an ending worth reaching.

"Skytopia" is a charming pixel-style fishing simulation idle game. Decorate a beautiful sky island at the base of your desktop, immerse yourself in a relaxing fishing lifestyle, and hatch and nurture a variety of adorable animals on the island.

Sit back and relax with Neko Station, a cozy 2D Pixel Art Desktop Idle Game! Manage your very own 'cat train,' decorating it with the perfect furniture to attract a diverse cast of feline customers. Pick them up at various stations and build friendships in this heartwarming adventure.

Raise your own virtual pet right on your desktop. Choose your favorite, take care of your companion, play together, train for battle, and help them evolve! They will always be there, keeping you company while you work, play, or browse.

Brewbie’s Alchemy Desk is a cozy idle simulation about potions and tiny magical helpers. On your enchanted desk, you’ll meet the adorable Brewbies—little spirits who happily run your workshop while you relax. Decorate your desk however you like and enjoy a slow, healing moment of magic.

Turn your desktop into a living prehistoric world. Dinosaurs roam along the bottom of your screen while you work, study, or browse. Collect, care for them, and grow your ecosystem over time.

Tiny Biomes is a relaxing idle game where animals peacefully produce resources and you gather wood in a calm harvesting zone. Build small biomes, earn gold, and enjoy steady progression without pressure, timers, or stress. Play at your own pace and unwind.

Idly gather and manage resources to repair what's left of a decaying world. Scavenge forgotten ruins, meet scattered survivors, and push back against the inevitable collapse. IDLE_DIRECTIVE is a grid-based inventory and resource management idle game.

Build and manage your own aquarium by collecting fish, earning money, and unlocking decorations. Feed your fish, clean the tank, and enjoy relaxing idle progression in this cozy 2D aquarium simulation.

An interactive and cozy raccoon fueled trash digging game for your Twitch viewers. Viewers can dig through your garbage with commands, subs, gift subs, and bit donations. Ideal for keeping chat engaged during content that requires extra attention, or while on long breaks.

In Fantasy Idle Dungeon, hatch and capture rare Jenin, awaken their legendary skills and talents, and experience the joy of leveling up, evolving, and fusing them. Freely customize your gear, assemble an unbeatable adventure team, and claim glorious victories with effortless idle gameplay!

Games are too stressful ... so I made one that literally plays itself

A cozy desktop idle game where cute slimes bounce around your tiny farm while you work or study.

Pirate Treasure Hunt is a short incremental treasure hunting game. Explore islands, uncover rare treasures and ancient artifacts, upgrade your expedition and become the richest pirate on the seas.

A chill clicker-idle stars hunting and constellations creation game that sits in the corner of your screen. Feel free to daydream while you are working or doing something else.

Harpooner is an action-driven incremental fishing game where you hunt bizarre alien fish from a meteor crash. Grab your gear, grow stronger with every dive, and take down massive bosses to save Earth's ecosystem!

Chonkers is a cozy and relaxing idle game. Adopt the cutest fur balls and watch them ramp up the chonk scale as you play with them. Find them a new family. They’ll pay A LOT for your hefty chonker! Complete your collection by finding all the breeds and the rarest space cats!

Click on fish, produce bubbles, and upgrade your aquarium! Hire Blobfish, discover rare Angel Fish, and watch out for sudden sharks in this relaxing clicker game. Are you ready to build your underwater empire?

A Good Day Fishing is a gamified focus tool where you catch fish while completing real-life tasks. Reel in and record new species, decorate your favorite cozy fishing spot, and customize your soundscape to create a custom vibe to help you relax and boost concentration.

A relaxing idle desktop farming game where you grow crops, gather resources, upgrade facilities, tease little birds, earn extra coins by clicking or typing, and expand your farm at a laid-back pace.

This game is a relaxing idle game where you grow your garden empire by swinging your scythe in beautiful isometric fields, collecting resources, and sprouting grass one by one.