Top similar games like Mutation Overload:

Happy hour has arrived! Become the NecroBouncer and toss out rowdy guests in a roguelike adventure through the nightclub dungeon. Raise the dead, discover hundreds of relics, ban enemies and gobble up their powers. It’s one hell of a good time!

Conquer different planets at war by hacking and slashing through plant foes in roguelike style missions. Watch over your mothership to unlock, upgrade and customize Jelly characters for accomplishing objectives and defeating powerful bosses!

Life Core is a roguelite action game where you explore uncharted planets. Fight, eliminate your enemies, and when you fall, unleash the power of the Core in your new body. But remember… the system is always watching!

In this fast-paced rogue-lite, your health points are your only resource: sacrifice them to acquire vampiric powers and devour your enemies to heal yourself! Beware: every drop of blood counts in this frantic race to defeat the apostles of the Cult of the Sun!

Wield Slasher’s sword in high-octane bullet hell roguelite action. Enter the trial for the cure to a deadly virus in the hostile microcosm of Deflector. Dodge and repel enemy projectiles, evolve with collected DNA and cut down all opposition.

Cryptical Path is an action rogue-lite that pushes the boundaries of the genre. Play the Architect, build your own rooms, and tame an ever-changing labyrinth you've been summoned in.

Ending Tau is an action roguelike where you morph your body parts with curses that completely change the game. Walk, fly, teleport, or dig your way across the jungle. Explore unique mechanics with endless mix-and-match upgrades, unravel a beautiful pixel art land, rebuild your village, and End Tau.

Twinspell is a cooperative roguelike where two players explore procedural dungeons and face enemies in fast-paced, frenetic combat.

Fight. Die. Rise. Until your vow is fulfilled. Thorn Knight is a dark isometric action rogue-lite where ruthless, combo-driven combat meets a tower twisted by cursed echoes and buried sins. Every fight tests your skill. Every floor leads you deeper.

Pick your favorite MOBA-style hero and jump into exciting roguelite runs! Overcome deadly challenges, grab game-changing power-ups, sync your build for devastating combos and save Lumerea from corruption!

Play as the mythological Chimera in this action-packed rogue-lite. Make your escape from a deadly tower filled with unrelenting enemies as you uncover its dark secrets. Enter this fantasy world and overcome intense challenges, find hidden lore, and discover the true reason behind your imprisonment.

Nether Dungeons is an action-packed dungeon crawler. Battle through procedurally generated dungeons, face relentless enemies, and defeat epic bosses. Customize your hero, wield diverse weapons, and survive intense challenges as you descend into ever-changing, dangerous depths.

Fight hordes of otherworldly monsters and explore procedurally generated dungeons in this addicting twin-stick action roguelike with beautiful pixelart. Mastering risk/reward mechanics and creating powerful Artefact synergies will be key to survive and escape the Demise Sanctuary!

In this hyper-stylized isometric fantasy rogue-lite, embark on a generations-long journey to defeat the corruption spreading from a nearby dungeon. Fight, die, upgrade, repeat, as you descend into the depths of the dungeon in order to make a name for yourself.

The Mixer is a unique take on a rhythm-driven rogue-lite where you create your own custom soundtrack by mixing-and-matching different music loops. Wield your own beat to conquer a dungeon full of rhythmic dangers.

Explore the sci-fi dungeons, collect loot, and negotiate the highest prices in this action roguelite, set in a 3D cardboard world. Grow stronger with each attempt. Be the unlikely hero.

Recreate yourself and break free from the simulation, in ICARUS84, a focused retro ARPG that will take over your mind and heart, but not your life. Make the build that plays the way you want to play, unravel the mystery behind why you're trapped, and find a way out.

Rise Again is an Action Roguelike inspired by Hack n Slash and Dungeon Crawler. Witness the adventures of a cursed wizard in ever-changing dungeons. Kill, Die, and Rise Again to lift the curse. Every death is a step closer to freedom. Will you break the curse?

An action roguelike fused with deck-building combat. Steal enemy abilities to shape your battle deck and unleash relentless, zero-cooldown combos.

Embark on an epic quest in this roguelite RPG where you explore dungeons, mine for gold, and battle fierce foes. Upgrade your gear, face daunting bosses, and uncover hidden treasures. Customize your hero with powerful loot and master new skills for endless adventure and surprises!

Will you dare to challenge the Cyberfield champions? Gather a unique combination of skills and enhancers in this roguelike game to rise to the pedestal of the best warriors of the steel arena.

An RPG Styled Roguelite set in fantasy procedural paths. Craft artifacts, slay legendary monsters and abuse synergies to fulfill the secret goal of your champion. Which one will you choose? We need your feedback before the official launch!

Explore this top-down dungeon crawler with semi-randomized levels. Find items like a boomerang and bow and more to defeat enemies, and collect soul crystals to access boss rooms.

Fight your way through randomly generated dungeons in this hardcore rouge-lite game. Discover your favorite character from a group of unique heroes and get powerful weapons or power-ups to save beautiful princesses in need.

Plunge into a living nightmare where every roll counts. Chain fluid combat with dice-fueled attacks, stack relics into ferocious synergies, and build unstoppable momentum. Slash through fate, bend chance to your will, and defeat the Black Die in this board-game inspired roguelite dungeon crawler.

An action roguelike indie game with secrets, loot, necromancy & ability progression from the creator of Songbringer. Each run you build a different sequence of weapons, abilities & relics while keeping your loot, character & world upgrades across runs. Play solo now. Local co-op coming soon.

Starward Rogue is a bullet hell twin-stick shooter. Blast your way through the Megalith, a rogue-lite labyrinth lodged in the side of a star. Customize your mech with a huge variety of weapons, perks, and upgrades. Steel yourself for the dangers that lurk in the depths of the dungeon.

Play as Cyrus, a medieval knight, in this top-down action roguelike. Battle your way through endless procedurally generated dungeons filled with coins and weapons. Discover rare, powerful modifiers and test your skills against a variety of deadly foes.

Use an extendable slime arm to “dissolve”, punch, grab, and throw enemies in order to save your slime brethren and navigate through the decrepit insides of an ancient Worm in this top-down hoard battler.

Helskate is a skateboarding action roguelite. Grind, perform tricks, and chain combos to power up your attacks to slay the monsters of Vertheim. Combine unique weapons and gear to suit your playstyle as you fight, die, and upgrade your abilities to come back to this labyrinth over and over again!

Echoes of Elpis is a twin-stick shooter sci-fi roguelike. Upgrade weapons, discover new tech, and uncover a secret past as you battle through Elpis on an epic treasure hunt.

Tears Apart is a fast-paced, dungeon crawling Action Roguelite. Tear through the decay with your dash strikes, commanding a delicate balance of evasion and aggression. Dive into the hollow realm, defeat creatures of void, and tune your combat tempo as you discover powerful and synergistic abilities.

Defeat the Titans as you battle your way into Tartarus to stop Chaos from conquering Olympus and destroying the world. In this rogue-like dungeon crawler adventure, you will play as Perseus, a demigod tasked with one mission; stop Chaos and the evil forces that surround him.