Top similar games like Rogue 21:

Thirteen: Risk & Rogue is a card battle game that blends roguelike survival with the strategy of the Chinese poker game Thirteen Cards. With a limited stack of chips, you must fight your way through multiple stages — each one a true battle of wits. Survive, and victory is yours.

Enter the dungeon, get lost and roll the dice against the monsters! Play your chances against dangerous monsters like ghosts, werewolves or even the frankenstein monster himself!

Cyber Pokeris a cyberpunk roguelike card strategy game. Use 150 Tech Cards (max 6) to combo-enhance poker hands (flushes, straights, etc.) & 36 Weapon Cards (max 3) to disrupt AI. Random shops/bosses/events. Conquer 8 levels (500–10k target pts), then Endless Mode. Master combos to win.

Mahjong Rush is an ink-wash mahjong roguelike deckbuilder. Build your scoring engine with Chows, Pongs, Kongs, Flower Cards, Talismans, and Relics, then cash in with a “Chips × Multiplier” payoff. Challenge yokai Bosses and win it all.

UP CARDS is a light roguelike card game. In this exciting journey, you need to control the card situation, play the best combinations, stack additional effects to turn the tide, choose your permanent rewards, and reach new heights through different strategic builds.

A roguelite deck-builder based on "Daifugo". If you can't play a card, you take damage: (Field Total) x (Multiplier). Use battle rewards to customize your deck and special cards in the shop. Strategize and upgrade to defeat even stronger enemies!

A dark fantasy deckbuilding roguelike featuring a unique Clash combat system, where every duel becomes an exchange of calculated moves and deadly counters.

《寻仙》是一款拥有Roguelike要素，融合修仙背景的卡牌游戏。在这里，每一局都是全新体验，不同的先天资质，搭配不同的法术卡牌，获得完全不同的法器，也能合成卡牌升级效果，构建专属卡组，从锻体-练气-筑基-结丹-元婴-化神，当然也少不了寻求奇遇、探索秘境，同时允许玩家剑走偏锋，构建体修/剑修/魔修甚至是傀儡卡组。

A roguelike deckbuilding card game, and a free entry to the Net. Build your perfect deck and defeat your very first boss!

ULTRAMASSIVE is a rogue-like deckbuilding game in a sci-fi setting. Embark on a journey towards the center of the galaxy, craft unique decks, fight hostile aliens, upgrade your space ship and face the unknown.

矩阵破冰者是一款卡牌构筑游戏。你将参与到一场数据盗窃的非法活动之中，为了赚取更多零钱突破层层安保，在这个过程中收集各种各样的程式卡片，利用它们组合出各种劲爆的化学反应。

Odds At Oddity is a blackjack based roguelike deck builder. Manage your power betting deck, create diverse combinations and scale your points as far as you can go!

A card roguelike inspired by Balatro and Cuphead. Fight duels, play insane mini-games, build Joker City and rise to greatness — in Three Jokers!

A roguelike deckbuilder where you gamble with your own genes. Every card played mutates your body. Every defeat triggers unpredictable mutations. Become a different monster every run. Losing has never been this fun.

A roguelike deckbuilding card game where you control, and buff your objects to defeat all kinds of funny sci-fi enemies.

Draw it, Store it, Strike hard! A charming casual deckbuilding roguelike with magical animal wizards! Strategically combine elemental cards—Water, Fire, and Lightning—and collect over 150 unique relics to build your deck, customize your playstyle, and save a world tainted by elemental corruption.

Incredibly complex card-based roguelike that challenges you to learn and exploit the nuances of chance, mastering luck itself.

Battle Stones is a single-player turn-based strategy deckbuilding roguelike. Place stones on a board and leverage their combo rules and special effects. Expand your deck and even merge stones to create more powerful moves. Will you master the art of the stones and win all your battles ?

This is a single player self-propelled chess game including the mechanism of chess synthesis, relic, magic, front and back row position and so on. Players need to buy pieces, choose relic, defeat more and more powerful enemies and finally win

King or Nothing: Your Choices Forge Your Fate.​​ Embark on an epic adventure that blends ​deck-building​ and ​character progression. Master the ​elemental advantage​ and strategically ​synergize your cards​ to crush your enemy. ​Will you claim the throne or fall into oblivion? The challenge awaits.​

Craft devastating decks, gather loot to define your build, and defeat randomized dungeons and ruthless boss fights in a journey of risk, strategy, and ruin in this fantasy roguelike deckbuilder.

Strategic roguelike where you've been selected to compete in the king sport of the future. 60 wildcards, infinite strategies, 7 customizable professional rivals, world ranking, and different game modes. Will you become a legend?

Welcome to the 'Breaker System'. Fight back against the system through a game of cards and free humanity from its systematic embrace as BREAKER. Combine the use of skill cards and powerful artefacts alongside tactical thinking to best the system and break through the advancing array of robots.

Puzzline is a 2-4 player board game connecting cards like a puzzle! Each card has a unique effect. Play them strategically and get the victory! Online play is also supported!

Your deck is your code. Build branching, looping programs from cards to hit byte targets and outwit rival hackers. A programming-themed roguelike deckbuilder with a heat-driven mastery climb, runaway combos, and a final boss who's been watching you the whole time.

Lead a band of lawless rebels and take the dark streets of StarCity in this fast-paced deck-building roguelike game, set in a cyberpunk world. Choose your next move carefully: every decision matters!

Roll the dice to shape your fate. Each throw triggers events as you explore and leap across tiles. Battle with cards, build your deck, and manage scarce resources. Time is limited—plan wisely and defeat the Demon King before darkness consumes all.

Battle waves of enemies in a tactical card battler. Combine neutral cards with boosts to create powerful attacks. Spend XP on permanent shop upgrades and use in-run skill points to adapt your strategy. A passion project from Void65.

MAJOR ARCANA - is a roguelike deckbuilder in which you need to collect your deck of cards, artifacts, trinkets and look for a path, building your way from tiles with events and battles.

This is a life-simulation roguelike card game. Harness item and skill cards to shorten your commute, continuously boost yourself through diverse events, forge connections with different friends to help each other out, and become the best employee who never arrives late.

A game combining chess and card games with roguelike elements. You can move with the cards in your hand. With only a joker piece as start, you can build up a powerful army. With Upgrade Cards changing how you play, and Curses that help the enemy, every run feels different.

We create a single player card adventure full of deadly suspense. Everytime you step into the mansion, you will experience the life in the mansion, face deadly opponents, randomly triggered mechanical rampage events, and various mysterious relics.

Net Raiders is a strategic roguelike deck-building game where you play by performing Card Merge.To survive the dangers of a crumbling virtual world, merge the cards in your hand and find the best moves to defeat the enemies you face!