Top similar games like Protocell:

Discarded is action rougelike, arena shooter where you face waves of relentless enemies. You’re alone and outgunned - move fast, shoot faster, dodge the bullets and upgrade on the fly. Keep up with the pressure or get shredded like the rest.

Your friend's "harmless" prank virus mutated and hijacked your PC! Luckily, your AI assistant is ready. Command an evolving fleet of cursors in this bullet-heaven roguelite. Purge swarms of mutating malware, stack game-breaking upgrades, and reclaim your system!

Roguelite action game with RPG elements in a world of grim bioengineering. Control a growing lab, craft monsters from body parts, boost them with random upgrades, and send them into ever-changing trials. Unlock modules, tweak builds, and adapt to enemies that change with every run!

Survive shifting universes where the rules themselves change. Build your arsenal across 15-wave runs, claim the Keys, and face a finale built from the worlds YOU conquered. Adapt or die — the strongest build means nothing in the wrong universe.

Gnomekeeper is a cozy-weird bullet-heaven roguelite. You’re one garden gnome, the sun has quit, and everything in the garden wants you gone. Fend off the swarm, cobble together a ridiculous build, and see if you make it to morning.

Dustdrifter is an incremental bullet heaven arena shooter. Venture into dangerous ruins, blast through overwhelming hords of enemis and collect valuable relics. Return home to upgrade your drifter and grow your village.

SURVIVE in a transforming arena against ALIEN OGRES in this ROGUELIKE BULLET-HELL 💥 MODIFY your gun, make smart upgrade decisions and master your spaceship's controls to conquer the OGRE CHAMBERS !

Bug Alliance is a top-down Action Roguelite where every level-up reshapes your build. Trigger Synergies, conquer 20-wave maps with boss finales, unlock a 13-chapter story on higher difficulties—then dive into Chaos Surge with endless bosses, curses, and risky rewards.

Happy hour has arrived! Become the NecroBouncer and toss out rowdy guests in a roguelike adventure through the nightclub dungeon. Raise the dead, discover hundreds of relics, ban enemies and gobble up their powers. It’s one hell of a good time!

Mow down endless hordes of enemies in the arena of this dark cyberpunk survival roguelite. Play as a fully modular robot, snapping together multiple weapons and components to craft your perfect build. Collect powerful items to forge game-breaking synergies and annihilate everything in the Pit.

Fight through neon-drenched survival arenas as a cyber cat-eared gunslinger, stacking weapons, upgrades, and chaotic builds against overwhelming enemy swarms.

A fast-paced physic-based roguelite shooter in a decaying star system.

A roguelike with unique curses, 60+ cards, incredible shots and power-ups. No two attempts are ever the same.

Star of Providence is a top down action shooter with procedurally generated elements. Explore a large, abandoned facility in search of incredible power, fighting dangerous foes and gaining new weapons and upgrades as you progress.

A bullet-heaven action roguelite where every byte counts. Delete malware, fuse powerful programs, and restore corrupted systems. Experience high-octane survival action in an executable that, along with an adaptive code-synth soundtrack, fits on a 1.44 MB floppy disk!

Demoman is a 3D top-down arena survival roguelite about a retired soldier who was perfectly happy living out his days with his cat, General Meow — until an alien invasion ruined everything. Now he's dusting off old skills, upgrading his arsenal, learning new tricks, and leveling entire city blocks.

Get ready for the ultimate space challenge! In this top-down action roguelite you’ll pilot your ship through a low-gravity environment, dodging obstacles and fighting enemies along the way. But be careful, one wrong move could mean the end of your journey. Are you ready to take on the challenge?

Roguefall is an action rogue-lite following a lost player guided by the enigmatic Overseer to scavenge a world forgotten by humanity. Fight, explore, collect, and fall until you reach the final machine: 0VR5R.

A fast-paced bullet heaven action roguelike set in a futuristic arena. Face overwhelming enemy waves, evolve your build with powerful upgrades, and survive escalating instability that constantly reshapes the battlefield.

Seedovia is a rogue-like dungeon crawler where you traverse room after room, fighting challenging monsters. Chain your weapons, collect game-changing passive upgrades, and equip items to create unique builds and become increasingly more powerful.

Scarlett's Dungeon is a retro-inspired action RPG dungeon crawler with roguelite elements. Explore randomly generated dungeons, fight monsters, and collect loot in beautifully crafted pixel art reminiscent of the Game Boy Advance era. Test your skills as you dive deep into ever-changing challenges!

Pillage and plunder across the galaxy as part of a crew of Space Vikings in this sci-fi roguelite bullet hell dungeon crawler. Find exotic weapons, upgrade them with powerful augments, explore mysterious alien planets, and unleash viking vengeance on their inhabitants.

Octomech Survivors is a top-down mech action roguelite focused on movement, survival, and auto-fire combat. Manage weight across 8 weapon slots, with up to 4 copies of the same weapon. Choose 1 of 3 mechs and create your own build!

Arcade mining under pressure: pilot a fast rover, mine resources, upgrade, fight, and rescue planets before aliens take control over the whole universe.

Creator’s Fall is an action roguelike with various classes, where you can choose between different paths. The goal is to reach and defeat the final boss at the end of the path. Levels are dynamically generated and feature different biomes. You can choose an upgrade after each level up.

In this fast-paced rogue-lite, your health points are your only resource: sacrifice them to acquire vampiric powers and devour your enemies to heal yourself! Beware: every drop of blood counts in this frantic race to defeat the apostles of the Cult of the Sun!

Worm Slayer is a Fast-Paced Bullet Hell Roguelike where you must fight your way through the dungeon that is the Worm King's den to finally reach and then defeat the Worm King.

Slay Goblins is an arena roguelite where you play a knight fighting off hordes of goblins. Choose from a variety of perks, weapons and items to create unique builds and defend your castle.

A fast-paced Bullet Hell roguelike where your "hero" is a heavily armored sewage truck. Drift through thousands of enemies, combine dozens of absurd weapons and passive skills. Upgrade your heavy machinery and survive the shift!

Sealer of Dungeons is an action-shooter with Rogue-lite elements. Play Sealers on their journey, you will find great treasures and abilities to seal the unknown evil above. Gather precious loot, discover hidden secrets, and chat with merchants to get powerful items. Seal the dungeon, save the world!

A pure neon arcade survivor-like: dodge swarming hordes, dash through walls of bullets and forge devastating builds from 200+ synergizing items. 6 ships with unique ultimates, 8 mega-bosses, rising Threat levels, endless mode and a daily challenge.

Aggrolotls is a top-down arena roguelike where you play as tiny axolotls and must evolve into a swarm that can take on powerful creatures from the sea. Level up and choose from upgrades that make each round feel unique.

BAFTA award winning fleet-based RTS meets rogue-lite. In Distant Star: Revenant Fleet, build your fleet of up to 5 ships from a choice of 8 classes and traverse a randomly generated galaxy to defeat the Erebus Platform. NOW AVAILABLE ON MAC AND LINUX

An action roguelite game with alien swarms and mechs. Battle enemies to make your way through a mass of spreading and evolving cells hosting dormant enemies. Collect a variety of game-changing skills and upgrades to create unique builds.

A roguelite bullet heaven where you dodge and auto-shoot through waves of enemies. Build devastating weapon, gear and mutation combinations with deep synergies. Face over 30 unique bosses across diverse biomes in this challenging arena shooter.

Skelly Selest is a score-attack hack slash dash run 'n' gun-athon. Venture into the procedurally generated perdition depths of Hell to purge the evil taint of the Deamonica Netherlords and their fiendly followers.