Top similar games like Protocell:

Discarded is action rougelike, arena shooter where you face waves of relentless enemies. You’re alone and outgunned - move fast, shoot faster, dodge the bullets and upgrade on the fly. Keep up with the pressure or get shredded like the rest.

Your friend's "harmless" prank virus mutated and hijacked your PC! Luckily, your AI assistant is ready. Command an evolving fleet of cursors in this bullet-heaven roguelite. Purge swarms of mutating malware, stack game-breaking upgrades, and reclaim your system!

Roguelite action game with RPG elements in a world of grim bioengineering. Control a growing lab, craft monsters from body parts, boost them with random upgrades, and send them into ever-changing trials. Unlock modules, tweak builds, and adapt to enemies that change with every run!

Survive shifting universes where the rules themselves change. Build your arsenal across 15-wave runs, claim the Keys, and face a finale built from the worlds YOU conquered. Adapt or die — the strongest build means nothing in the wrong universe.

Survive the night shift at a possessed print shop. You pick your tool, clock in at 10 PM, and mow down waves of printer's devils until the morning edition ships at 6 AM. You level up, evolve your arsenal, get PRINTED or get PULPED. A roguelike bullet heaven where ink runs. So should you.

Gnomekeeper is a cozy-weird bullet-heaven roguelite. You’re one garden gnome, the sun has quit, and everything in the garden wants you gone. Fend off the swarm, cobble together a ridiculous build, and see if you make it to morning.

Dustdrifter is an incremental bullet heaven arena shooter. Venture into dangerous ruins, blast through overwhelming hords of enemis and collect valuable relics. Return home to upgrade your drifter and grow your village.

SURVIVE in a transforming arena against ALIEN OGRES in this ROGUELIKE BULLET-HELL 💥 MODIFY your gun, make smart upgrade decisions and master your spaceship's controls to conquer the OGRE CHAMBERS !

Bug Alliance is a top-down Action Roguelite where every level-up reshapes your build. Trigger Synergies, conquer 20-wave maps with boss finales, unlock a 13-chapter story on higher difficulties—then dive into Chaos Surge with endless bosses, curses, and risky rewards.

Happy hour has arrived! Become the NecroBouncer and toss out rowdy guests in a roguelike adventure through the nightclub dungeon. Raise the dead, discover hundreds of relics, ban enemies and gobble up their powers. It’s one hell of a good time!

Assemble your own combat machine from interchangeable components and weapons to mow down hordes of enemies in the arena of this dark cyberpunk survival roguelite. Every part changes your build — combine them to create devastating synergies to survive increasingly brutal waves.

Fight through neon-drenched survival arenas as a cyber cat-eared gunslinger, stacking weapons, upgrades, and chaotic builds against overwhelming enemy swarms.

A fast-paced physic-based roguelite shooter in a decaying star system.

A roguelike with unique curses, 60+ cards, incredible shots and power-ups. No two attempts are ever the same.

Deepforge Brawl is a dwarven arena roguelite where your weapons fire themselves — you just have to survive. Charge your beard, chug your ale, and dash through goblin hordes across six depths of the mountain. Merge 17 weapons, forge 7 Masterworks, and descend until the Maw takes you.

Star of Providence is a top down action shooter with procedurally generated elements. Explore a large, abandoned facility in search of incredible power, fighting dangerous foes and gaining new weapons and upgrades as you progress.

Get ready for the ultimate space challenge! In this top-down action roguelite you’ll pilot your ship through a low-gravity environment, dodging obstacles and fighting enemies along the way. But be careful, one wrong move could mean the end of your journey. Are you ready to take on the challenge?

A bullet-heaven action roguelite where every byte counts. Delete malware, fuse powerful programs, and restore corrupted systems. Experience high-octane survival action in an executable that, along with an adaptive code-synth soundtrack, fits on a 1.44 MB floppy disk!

Demoman is a 3D top-down arena survival roguelite about a retired soldier who was perfectly happy living out his days with his cat, General Meow — until an alien invasion ruined everything. Now he's dusting off old skills, upgrading his arsenal, learning new tricks, and leveling entire city blocks.

Roguefall is an action rogue-lite following a lost player guided by the enigmatic Overseer to scavenge a world forgotten by humanity. Fight, explore, collect, and fall until you reach the final machine: 0VR5R.

A fast-paced bullet heaven action roguelike set in a futuristic arena. Face overwhelming enemy waves, evolve your build with powerful upgrades, and survive escalating instability that constantly reshapes the battlefield.

Seedovia is a rogue-like dungeon crawler where you traverse room after room, fighting challenging monsters. Chain your weapons, collect game-changing passive upgrades, and equip items to create unique builds and become increasingly more powerful.

You beat a wild boar with a slipper in the parking lot behind the apartment blocks. You pelt the Concrete Garden Gnome with pierogi. You pay in bottle caps. Osiedlowy is an action roguelite about every legend your neighbourhood has ever spawned - and how long you can keep running from them.

Scarlett's Dungeon is a retro-inspired action RPG dungeon crawler with roguelite elements. Explore randomly generated dungeons, fight monsters, and collect loot in beautifully crafted pixel art reminiscent of the Game Boy Advance era. Test your skills as you dive deep into ever-changing challenges!

Pillage and plunder across the galaxy as part of a crew of Space Vikings in this sci-fi roguelite bullet hell dungeon crawler. Find exotic weapons, upgrade them with powerful augments, explore mysterious alien planets, and unleash viking vengeance on their inhabitants.

Arcade mining under pressure: pilot a fast rover, mine resources, upgrade, fight, and rescue planets before aliens take control over the whole universe.

Octomech Survivors is a top-down mech action roguelite focused on movement, survival, and auto-fire combat. Manage weight across 8 weapon slots, with up to 4 copies of the same weapon. Choose 1 of 3 mechs and create your own build!

Project Sundive is wave-based arena auto-shooter roguelite, focusing on ship customization and ridiculously overpowered builds

In this fast-paced rogue-lite, your health points are your only resource: sacrifice them to acquire vampiric powers and devour your enemies to heal yourself! Beware: every drop of blood counts in this frantic race to defeat the apostles of the Cult of the Sun!

Worm Slayer is a Fast-Paced Bullet Hell Roguelike where you must fight your way through the dungeon that is the Worm King's den to finally reach and then defeat the Worm King.

Creator’s Fall is an action roguelike with various classes, where you can choose between different paths. The goal is to reach and defeat the final boss at the end of the path. Levels are dynamically generated and feature different biomes. You can choose an upgrade after each level up.

Sealer of Dungeons is an action-shooter with Rogue-lite elements. Play Sealers on their journey, you will find great treasures and abilities to seal the unknown evil above. Gather precious loot, discover hidden secrets, and chat with merchants to get powerful items. Seal the dungeon, save the world!

Slay Goblins is an arena roguelite where you play a knight fighting off hordes of goblins. Choose from a variety of perks, weapons and items to create unique builds and defend your castle.

Leaping Dungeon is a frog first bullet heaven with lots of jumping and roguelike dungeon exploration in the world of frogs vs flies. Wield 6 weapons and 3 tongues at the same time. Beat rooms swarming with flies, fight bosses blocking the way down, and track down the Fly Lord!