Top similar games like Cartridge Defense:

We clapped the Minion Meta. No armies to manage. No 1/1 tokens to trade. Just you, and the miscreation in front of you. Apocalypse: The Hunger combines deep RPG progression, item crafting, and the tactical return of "The Stack" in a brutal, high-stakes card battler where you play for keeps.

Haxity is a cyberpunk, PvP, action deck-builder. Draft your deck, modify your fighter and outsmart your opponent in intense Head-to-Head battles. Fight online, challenge your friends or terminate the AI. Slot, hack and execute, welcome to Haxity!

A tactical card game built on Estro type clashes. Win the 5-stat duel to claim Dominance, then spend banked Quantum Charge to Overload the fight, multiplying your edge and turning a close call into a rout. Solo campaign, AI battles and ranked PvP.

Dive into Becoming Captain: Build your deck mid-battle in this Roguelike Deckbuilder. Set in a sci-fi realm where piracy is nearly eradicated, except aboard the notorious Calamity. Craft a tailored card deck on the fly while battling for your survival! Will you become its captain or die trying.

Renegade Run is an immersive deckbuilder that puts you in the pilot seat of an experimental starship. Discover anomalies, carve your path, and face powerful enemies as you battle your way back to Sector 0.

The fusion of deck-building roguelike and tower defense returns, bigger than ever! Build your deck with powerful new cards, unlock unique trinkets, and deploy enhanced towers to overcome relentless waves of enemies and new strategic challenges.

A relaxing card game with real-world side quests. Match inspiring and reflective quotes, combine special effect emblems, do out of game side quests and build your deck to get high scores. Reflect, relax, and walk away feeling good after you've finished playing.

A rogue-like deck-building experience set in the dark fantasy world of Port Haven. Featuring innovative CARD FUSION, CARD UPGRADES & CARD CYCLING systems.

DEFEND 99 is a rogue-lite tower defense game with deckbuilding and autochess elements. Place your turrets, roll for upgrades, equip Mods and Buddies, balance your economy and prepare your board strategy for enemy empowering weather effects. Can you hold off all ninety nine waves?

A dark 1930s cartoon roguelike deckbuilder fused with real-time tower defense. Turn cards into living towers, survive escalating waves, choose risky routes, buy new cards, and stamp powerful sigils into your deck.

The cyberpunk deckbuilder. Null Runner is a roguelike card game where you hack MegaCorp servers, break down their firewalls, and steal their secrets before the corpos flatline you.

Pulsars and Crowbars is a rogue-like deck builder that combines grid-based tactical gameplay with character-driven storytelling. Unlock cards, craft your deck and save the galaxy!

System Crash is a story-driven cyberpunk collectible card game inspired by Blade Runner and Neuromancer. When corporations own everything and the line between man and machine is blurred, your only option is to fight to survive!

Explore the galaxy in Star Deck, a replayable roguelike card battling sci-fi adventure! Rescue your brother from the Federation, an uncompromising totalitarian presence that rules the galaxy with an iron fist. Endless story loops with unlockable new weapons, cards & items will keep you coming back!

Friends to your face, foes to your scoreboard. A sci-fi deckbuilding roguelike where you cooperate to survive the onslaught, then sabotage your friends to stay on top. Play solo, with bots, or team up online

Net Raiders is a strategic roguelike deck-building game where you play by performing Card Merge.To survive the dangers of a crumbling virtual world, merge the cards in your hand and find the best moves to defeat the enemies you face!

Climb a cyberpunk tower in this turn-based roguelike deckbuilder. Collect cards, manage resources, choose risky routes, and build powerful synergies. Adapt to shifting enemies, events, and rewards as every run creates a new tactical challenge.

A hybrid card game and tower defence where the hands you play become the towers you build. Defeat the enemies approaching the bear's den and find modifiers that support the elements of your defensive strategy.

A roguelite deckbuilder crossed with a CCG, set in a dark cyberpunk world. You will lead a three-man squad against competing factions fighting among the ashes of a world-wide war. Each operator comes with a unique deck that can be customized and augmented.

Click Them Off is a hand-drawn roguelike deckbuilder. Conquer a strict hand limit by refreshing the store to stack identical cards, fusing them into unstoppable power. When nasty humans invade to steal your resources, wield three unique weapons to click them off!

We fused deck-building roguelikes and tower defenses in a way never seen before - deploy your towers, collect valuable trinkets and cast powerful spells to defend yourself against the Salkoth!

It's 1999. You owe a Busan loan shark ₩200,000,000, and the only thing you're good at is Go-Stop — Korea's flower-card game. Match cards, stack multipliers, call "Go" to double it all. Interest is due every third night. Miss it and they send someone.

Save humanity with six girls! This is a Deckbuilder roguelite game. Reclaim the lost surface and experience the stories of each android girl. You have 30 days to defend humanity's last stronghold

Faraway Galaxy is a card-based roguelite about a battle-hardened space wolf in a bizarre galaxy, focused on short, intense tactical battles and meaningful decision-making. Fight alien pirates, collect artifacts, and uncover new encounters!

FOIL QUEST: is an RPG roguelike deck builder! Choose a hero, build your deck as you go. Complete quests, face final bosses. Win or lose, your card collection keeps growing! If you've been wanting a new deckbuilder roguelike with a focus on combos and synergies, give FOIL QUEST a try!

ULTRAMASSIVE is a rogue-like deckbuilding game in a sci-fi setting. Embark on a journey towards the center of the galaxy, craft unique decks, fight hostile aliens, upgrade your space ship and face the unknown.

A roguelite deck-builder based on "Daifugo". If you can't play a card, you take damage: (Field Total) x (Multiplier). Use battle rewards to customize your deck and special cards in the shop. Strategize and upgrade to defeat even stronger enemies!

A single-player draft style take on the three lane, twelve card gameplay you know and love. Test your deckbuilding skills and choose from over 200 cards, no grinding required. Play the decks you want to play: Random decks, sealed draft, build your own, or import a deck code from *somewhere* else.

packet.Breach() is a roguelike tower defense where you deploy hacker programs to manipulate and redirect projectiles to attack your enemies. Build your deck and join a hacker faction, or choose to remain unaffiliated and become a legend.

Collect, construct and conquer. Choose your Faction and dominate the city. Collect cards, expand your Influence and crush your rivals!

The roguelike auto-battler where your deck prints itself! Supply a brave worker droid with synergistic blueprints to defend the planet against hordes of alien invaders. Combine hundreds of cards with custom upgrades and infinitely stackable modules to discover broken builds.

"Atman Rebel Flame" is a cyberpunk card-building game that supports multiplayer battles with no external numerical growth to ensure fairness . Choose your hero and support cards, elevate your phase and select talents, defeat opponents and claim victory!

CITY WARS: TOKYO REIGN takes the customisation and strategy of a traditional CCG and introduces a dynamic battlefield where tactile mechanics and turn-based battling combine. Choose a FACTION, build a COMBAT CASE and take to the streets.

Rottenlands is a tower defense deckbuilder where you build a deck of units, towers, and abilities to hold back waves of Mold-corrupted enemies and protect the kingdom.

Null and Void is a darkly satirical deckbuilding tower defence where even death doesn't free you from debt - your clone just inherits the bill. Only mining pays enough to survive and that means destroying entire worlds, but hey, there are always more planets.