Top similar games like Patient Zero:

Blast robots to bits in this action rogue-lite shooter which focuses on satisfying gunplay and thousands of fun builds! Mechs invented "Mood Solution" to replicate their creators, but lords got possessed by emotions. Fight with friends or by yourself to annihilate hordes of deadly bots.

The game is a Dungeon Crawler, where the player must survive the succeeding dungeons and defeat Impeficus on his throne.

Cut down Thousands of enemies, from the undead to the mysterious creatures of the night to save the world from the impending doom, Rune Break is a Fantasy Rogue-lite where you fight hordes of enemies with casual elements.

A co-op roguelike for 1-4 players with missions and levels that include classic gameplay of pinball, brick breaker, mini-golf and soccer combined with ninjas, stats, power-ups, and enemies. Build your clan, crush the darkness.

"Touhou ~Red Empress Devil." is a bullet-hell shooting roguelike action game. Set in The Scarlet Devil Mansion, the inhabitants of Gensokyo go on a rampage!

Trapped in a deadly gameshow, in order to survive, you will need to fight mutated creatures, use crazy weapons & abilities, collect treasures, avoid sinister traps and obtain insane power-ups in this Top-Down, Twin-Stick Shooter with a wacky FMV/Low-CGI style and multiple Single+Multiplayer modes.

Full Mojo Rampage is a rogue-like game that takes place within the confines of the Voodoo reality. In this realm only the most powerful rites and powers can provide a safeguard against evil. Dying is not the end, only the beginning to becoming a stronger voodoo soul!

Roguelite Overpowered Wizard Simulator & Dungeon Crawler. Slay hundreds of cultists using the power of ancient cards and your magical arsenal. Choose from a diverse set of cards to create unique, game-breaking builds and shoot down the horde trying to stop you from climbing the tower of babel.

In this fast paced twin-stick roguelite platformer, you play as an unnamed child ascending an ominous clocktower in pursuit of their lost memories. Harvest and sacrifice souls to grow your power in order to challenge procedural encounter rooms and intimidating bosses!

Now is the time for justice! In this Roguelite game, players will be able to learn spells, strengthen skills, use the currency obtained from battles to purchase items from mysterious merchants, kill numerous demon claws, and ultimately conquer this world!

Rain down hell on the robot army in DUST & NEON, an award-winning best-in-class post-apocalyptic shooter where twitchy-finger gunslingers are rewarded with fame and glory.

The Lightless World is a PC reverse horror action RPG co-op game set in a cosmic horror universe where players control demonic god protagonists.

A charming 3D roguelite platformer about a normal day in the life of a knight! Sharpen the spear and make the Dragon run in fear! Oh, and also try to manage a date with princesses & princes you rescue.

Rightfully, Beary Arms is a bullet hell roguelite that is about much more than collecting loot, dying and losing everything. Carefully choose enemy upgrades against your own, then plan your dungeon crawl tactfully to gun through unique factions of enemies, strategically preserving loot after death.

SURVIVE COUNTLESS HORDES, BE A ONE MAN ARMY, DIE AND RETURN STRONGER. Halftime Heroes is a Survival Rogue Action RPG game with short and intense matches where you learn spells, level up, acquire loot and fight bosses. Each time you die you may upgrade or unlock several features.

Prepare for epic battles between gods and Hades in this top-down action roguelite! Choose your deity, unleash powerful combos, and fight against underworld enemies. Feel the adrenaline for 15 minutes and restore order in the underworld.

Battle Shapers is an action-packed, sci-fi FPS roguelite in which you shoot and smash your way through swarms of corrupt robots. Wield powerful weapons, abilities and game-changing new powers stolen from ruthless Overlords.

Juicy army is the sweetest action roguelike set in a dream universe where you'll have to fight an army of juicy creatures!

LightBear is a randomly generated action RPG whackathon with heavy Rogue-like elements. Players will lose their vision the further from the starting point they get. Don't be deceived by its appearance, this game will challenge you to no end. Watch out for 100's of randomized monsters.

Star Bind is an increasingly fast-paced action dungeon crawler where you'll need to shoot, dodge, loot, learn, and improve to escape a bizarre simulation.

Unleash mythic heroes and their mighty vehicles in this thrilling co-op action roguelike. Seamlessly shift into car form, create builds with unique abilities, and battle endless enemies to stop the evil Dominion. Rev through high-octane missions, conquer epic bosses, and become an absolute legend!

Whether you choose magic, swords, or both, make your way through the thousands of monsters attacking you! DunJumb is a colorful 2D medievial survivor game with roguelite elements, in which you create, buy and reinforce a combination of weapons against formidable enemies!

Void Soul Awakening is a 3rd person action rogue-lite that fuses the heart-pounding elements of hack and slash mechanics with the intensity of a shooter. In a world of unrelenting action and adventure, you are casted as an immortal vessel struggling to escape from the clutches of an undead prison.

Genome Guardian is a top-down roguelite turret shooter where you must defend yourself from hostile aliens at the microscopic level. Combine & discover 70 weapons across 4 modes using a vast array of turrets, perks, modifiers and power-ups on this vibrant journey to the depths of the abyss.

A top-down twin-stick shooter that pays homage to the golden era of arcade classics. With its vibrant 2D retro pixel art style, this game offers a blistering blend of intense shooting action, dynamic combat, and strategic gameplay.

Discover the beauty and fragility of life in Survivor Cells, a unique survival game against viruses and bacteria, which strategically combines the elements of roguelite, bullet hell and tower defense in a challenging experience. Your destiny depends on your agility and choices. How far will you get?

"Towers and Survivors" combines rogue-like action with tower defense. Strategically build and upgrade towers, manage resources, and use various skills. Each choice is key in this engaging, strategy-based game.

Battle time and terror in a shoot & survive extraction roguelite. Select your hero and survive the relentless cosmic surge. Shoot, level up, topple bosses, and amplify your powers to cosmic levels. Embrace the Blastard within and unlock new heroes, powers, and perks to use on future runs.

Come and fight with Doobi to slay the evil monsters and bring peace to the family! Watch out, as only your strategies and upgrades will help you find the right set of combos. Let's venture deeper into the woods!

amazin' Mage is a top-down, randomly generated dungeon crawler with crafting and with excellent replay value!

Chaos wakes up from the darkness and erodes Hades of hell. Hades opens the door of hell, and the devil and chaos of hell come to the world. Chaos erodes the earth, and the gods who can fight against chaos are missing. Only the sun goddess and the God of love protect human beings against Hades.