Top similar games like Tower of Ascension:

A roguelike tower defense game with a dash of deckbuilding. Choose a reward, improve your build, survive the next wave, repeat. Highly replayable, difficult, and addictive. You'll want just one more wave, just one more run!

Vault of the Void is a fast-paced roguelike deckbuilder where the power is in your hands. Continuously customise your deck, crafting powerful combos and ingenious strategies. Upgrade your cards with Void Stones, infusing them with new abilities to help defeat the minions of The Void!

A fusion of tower defense games and roguelike deckbuilders. Use your cards to build towers and to upgrade them in unique ways. Gain rewards to customize your deck, defense and playstyle. Break the shapes before they break you!

Gate Guardian is a fantasy roguelite in the horde survival genre. Take advantage of unimaginable freedom in creating your magic spells. Build perfect combinations of skills, change and modify them. Defend Life and Survive Death!

A minimalist sci-fi tower defense. Buy soldiers and upgrade them, defeat waves of enemies, hold your lines.

Adventure with your unique friends and defeat powerful enemies! UNILOGUE is a new tower defense game with elements of a build-your-own roguelike. Form the best party you can think of and set out on a rugged adventure!

Build mazes, customize your deck and travel through time, in a nostalgic tower defense game with a minimalist feel and a rogue-lite twist. Only you can save the Tree of Life from the malevolent forces of The Corruption...

Build twisting mazes with tetromino blocks and deploy unique towers in this engaging roguelite tower defense game!

Discover an endlessly replayable roguelike deckbuilder. Craft a unique deck, collect powerful relics, harness potent magic and enhance cards with "Boost" to overcome the challenges ahead as you set out to Seal the Rift!

A fusion of roguelite, tower defense, city-building, and deck-building! We created a new kind of real time strategy game filled with addictive and fast-paced gameplay. Create your deck, defend your city, and build the largest Ratropolis in history!

A completely new style real-time card battle "Overdungeon" Overdungeon combines rogue-like, tower defense and card games. More than 100 cards are Attack, Animal, Building, Spell, Trap, etc..Build your creative and crazy deck!

Delve into grid-based tactical combat in this roguelike deckbuilder. Coordinate your heroes, modify your cards with unique runes, construct powerful item builds, and sidestep card-corrupting terrain to survive a gauntlet of befouled enemies.

Northwind is a monster-hunting rogue-lite deckbuilder. Hunt monsters, gather resources, and explore card crafting in Northwind Town. Discover new monsters and unlock town upgrades as you increase your hazard level.

Play the first deck of Shapebreaker for free. A fusion of tower defense games and roguelike deckbuilders. Use your cards to build towers and to upgrade them in unique ways. Gain rewards to customize your deck, defense and playstyle. Break the shapes before they break you!

Engage in adrenaline-pumping card battles with 30+ beautiful girls! Use the quirky Joker cards to transform your poker deck, or achieve record-breaking scores with unique card combinations. After conquering the challenges, unlock a stunning gallery of the girls' exquisite artwork!

Become the hero who protects the fantasy world and stop the monster invasion! 'Legacy of Defense' combines defense with deck-building. Build your deck, use powerful skills, gain experience, upgrade, clear stages, and defeat the final boss. Ready to test your strategy and luck?

Portal of Defense is a strategy Roguelike tower defense game. The game can complete all operations by simply dragging and dropping with the mouse. Explore the portal and obtain powerful items to become stronger and resist the tide of enemy attacks.

Deck Hunter is a roguelike card game. The World of Klanojh has been cursed by Glatta, the Goddess of Anger. Build your deck, make combos, defeat fantasy creatures and help Avery to face the evil and restore the balance!

Gothic × Sickがテーマのデッキ構築型ローグライト。10枚のカードを入れ替えながらデッキを強化。攻撃をして敵を倒すか、防御に徹して耐えるか、2通りの戦略を上手く活用しよう。

A dynamic tower defense/deck-building game with roguelite mechanics! Build towers, protect your pyramids, and create your own strategy. Drafting towers is an addictive real time strategy game.

Assemble a team of Heroes to take down the AI overlord in this roguelike auto-battler. Master the elements, manage your timeline and build the strongest team possible.

Choose your Tamer and fight dangerous creatures with your companions - powerful Mystlings! Travel the mysterious world of Dragon Eclipse. Catch and train Mystlings to put together your own team! Build a strong card deck and create efficient synergies of three Mystlings to fight your enemies.

Dark Mist is a card game that combines elements of the roguelike deckbuilder genre with enemies that appear in waves. Defeat monsters and level up during battle to keep yourself going.

Iris and The Giant is a fusion of the CCG, RPG and roguelike genres. You play as Iris, who must brave her fears in her imaginary world. Dive into a melancholic and gripping adventure, filled with cute monsters and buried memories. Ready to face your inner demons?

Investigate your own death, find ways to break free from a time loop, choose a hero who will ascend to the throne and rule the Northern gate! The fates of whole nations of the land of Midian depend on your choices.

Arcane Array Arena is a shooting auto-battler game that "Combines Offense and Defense". You summon items in a magic circle and shoot them against your opponent! Create your own unique item builds, compose the most powerful deployment, and defeat your opponents!

Call of Zadeus [Zuh-day-us] is an open-world roguelike deckbuilder with a late 90's aesthetic. Travel across a huge procedurally generated world, collect cards, battle enemies, delve into dungeons, and defeat the unimaginable Zadeus!

Melt sand, shatter glass, and rust iron in this epic elemental tower defense game. Combine elemental effects to beat powerful materials. Use cunning strategy and wit to take on impossible challenges. Unlock new abilities and power as you embark on this difficult journey.

Dungeon Decks is a roguelike deckbuilding game where you create custom characters, craft unique decks, and recruit up to 4 allies. Collect powerful party buffs, battle monsters, and choose your own path in procedurally generated dungeons!

Gather bees to fight hordes of enemies in this RogueLike TowerDefense, collecting various relics to become the most powerful and defeat all those who get in your way.

We fused deck-building roguelikes and tower defenses in a way never seen before - deploy your towers, collect valuable trinkets and cast powerful spells to defend yourself against the Salkoth!

Seize forbidden treasures. Summon alien gods. Feed on your disciples. Cultist Simulator is a game of apocalypse and yearning. Play as a seeker after unholy mysteries, in a 1920s-themed setting of hidden gods and secret histories.

Immerse yourself in Soulkin, a tactical, monster-collecting Roguelite. Play as Nadia, a heroine summoned to save the world of Ankiril. Collect unique Soulkin, engage in strategic, turn-based battles on a hex grid, and defeat powerful foes to unlock new content and stop the corruption on Ankiril.

This card game combines elements of roguelike and deckbuilding. During the game, you shall strive ahead, gathering cards to build a unique deck and use it to defeat the enemies getting in your way. You will have to choose between escaping or try to defeat Death, who is relentlessly pursuing you.

“Natti” is a roguelike tower defense game unfolds in the Otherworld of Korean folktales. Place defense towers, collect equipment, and strategically utilize various heroes to defeat all the monsters and protect the Otherworld with “Natti”, goblins in form of animals.

Use ships to attack and destroy enemy space stations in real time.  Navigate through different randomly setup star maps to get to the exit and win.  It's a 2D single player space game that's massively replayable.