Top similar games like Isotopia:

Land with your friends on the surface of various planets, gather resources, create items and buildings, defeat enemies and move to other planets to discover their secrets and secrets

Within the Cosmos is a sci-fi RPG. After awakening in a secluded star system, you soon discover a fractured human society grappling with an emerging android threat. Explore planets, uncover mysteries, and navigate differing philosophies. Your choices will shape how the story unfolds.

HIRAETH is a sci-fi, first-person survival game set on a desolate, alien planet. Adapt to various threats while discovering the secrets of the abandoned, dystopian colony. You can choose between two distinct game modes that share common gameplay mechanics - sandbox and story.

Vault-Tec engineers have worked around the clock on an interactive reproduction of Wasteland life for you to enjoy from the comfort of your own vault. Included is an expansive world, unique combat, shockingly realistic visuals, tons of player choice, and an incredible cast of dynamic characters.

Bethesda Game Studios, the award-winning creators of Fallout 3 and The Elder Scrolls V: Skyrim, welcome you to the world of Fallout 4 – their most ambitious game ever, and the next generation of open-world gaming.

Lead a rebellion against tyranny in this open-world, survival sci-fi RPG game. Utilize alien technology to explore, build bases, craft, and farm. Prepare for an unequal combat to rescue humanity from tyranny and a mysterious deadly virus.

Pilot your starship in Starship Fighters: Galactic Warfare, a high-octane 3D space combat simulator. Engage in intense battles, explore vast galaxies, and unleash destruction with an arsenal of powerful weapons in a universe teeming with enemies!

QANGA: Dive into a sci-fi adventure of exploration and resilience across the cosmos. Merge your mind with a state-of-the-art cyborg crafted by ICLab's Industry labs, and journey through this expansive universe!

Immersive first-person roleplaying adventure with a focus on exploring a rich handcrafted fantasy open-world filled with interesting places to find, powerful items to collect, challenging enemies to defeat, ancient mysteries to solve and, ultimately, good friends to make along the way.

You will find yourself on the edge of space, on one of the space stations. A place where travelers, research scientists, traders and adventurers from all corners of the galaxy gather. But is everything so safe?

Explore a vast universe, uncover the mystery of humanity's demise, gather resources, build bases, and scan the unknown. Your journey awaits in this post-apocalyptic sci-fi adventure.

Alien zombies survival game, open world survival.Game uses unreal engine 5

Beyond Mankind: The Awakening is an indie old school type RPG taking place in a post-apocalyptic world. The game sports a mature and deep narrative, rich exploration, tense combat, and immersive RPG mechanics.

Think in reverse. Outsmart the impossible. A mind-bending first-person adventure where you solve ingenious and complex puzzles by rewinding objects through time.

Redacted:Genome is a survival action horror game where the player is given the ability to swap between various arm powers and rifle barrels to fight off enemy mimics in the third or first person. Craft ammo, food, and upgrade your abilities for the greatest chance at survival.

Fractured Atmosphere is an atmospheric VR exploration game. Scour abandoned spaceships and avoid hazards in your search for valuable items. Send crew to dangerous environments where each ship you explore will help to paint a picture of this universe and the people who live here.

EVE Vanguard is the online sci-fi sandbox FPS set in the EVE Universe, taking place 21,000 years in the future on far-flung worlds across the star cluster of New Eden, in which decisions have consequences and loss has meaning.

CyberFall is an open-world survival game set in a post-apocalyptic Cyberpunk setting with base-building and crafting. Players fight to survive against new threats as well as each other.

Anipocalypse is a humoristic post-apocalyptic first-person shooter. Use an arsenal of guns to shoot your way through hordes of zombies and mutated animals to complete your mission in this first-person "bullet-hell" shooter!

The world has ended. You are deep underground, and all alone with a cheery AI companion. You will have to mine and build to survive, and search for other survivors to help you. Will you be able to reach the surface? And what will you find when you get there?

NEX:OS is a community driven Ability/Movement focused Looter-Shooter style FPS game set in a war torn future. You play as a Centurion, a Biologically and Cybernetically enhanced near-immortal super soldier.

Over The Ruins is a post-apocalyptic blacksmith simulator with retro graphics. The player can explore the world, collect resources, create machines, upgrade your house and of course, forge incredibly customizable weapons.

In the year 2204 an average engineer gets an ordinary job offer that ends up being a lot more than he bargained for...

Voidless is a sci-fi space survival sandbox set in the near future within a realistic scale solar system. In first or third person, players can explore planets and asteroids, collect resources, and craft items. As well as building bases and ships, all with physics based flight and combat.

Tesera is a sci-fi sandbox game in a mysterious alien world. Explore an endless voxel world, defend yourself against aggressive creatures and drones, building your dream settlement alone or with friends.

After a mysterious accident you are left are stranded, floating through space on a piece of a space station. Craft supplies and Hubs to expand what is now your home. But be warned space is a dangerous places where one mistake can mean certain death. Can you defy the odds and survive in space?