Top similar games like Slime mutation:

Dungreed is a 2D side-scrolling action game with 2D Rogue-LITE elements. You become an adventurer exploring a continuously evolving dungeon to prevent the town from being destroyed. Eliminate enemies, use a variety of weapons and magic, eat food, and defeat evil in the dungeon!

Sidequest Survivors is a bullet-heaven roguelite where you control wacky characters, mow down waves of magical creatures, and tackle sidequests. Choose from a variety of weapons and create builds that match your playstyle.

Face challenging bosses and hordes of enemies in an action roguelike, using elemental weapons and unique combinations to master each cycle.

Pixel Descent is an action rogue-lite in which you navigate a series of complex dungeons packed to the brim with monsters that want you dead. Sign the contract and descend into the deepest depths of the abyss knowing full well that you will definitely die there, it's just a matter of when.

Mystical Map is a rogue-lite that allows players to draw out their own path in each playthrough. Maps are randomly generated, but YOU have the ability to choose your path and use any items found to enhance it. Chart your course and take on various action platforming challenges!

Rogue Legacy is a genealogical rogue-"LITE" where anyone can be a hero. Each time you die, your child will succeed you. Every child is unique. One child might be colorblind, another might be a dwarf with vertigo. But that's OK, because no one is perfect, and you don't have to be to succeed.

Deadly missions for a deadly group! TH3-M15 Guild is a bullet hell survival game with rogue-lite elements. Undertake assignments, fighting off against armies of robots and creatures alike. Use an arsenal of unique skills, weapons, and items! Do you have what it takes to finish the job, mercenary?

Delve into the mystical depths of the Emerald Forest in this captivating roguelike. You play as a courageous fox, wielder of powerful spells, the last bulwark against the growing corruption.

Smol Survivors is a 2D reverse bullet-heck where smol blocks have become lost and need to find their friends and a way back home while fighting through hordes of enemies.

Don't Go Unarmed is a randomly generated action RPG shooter with heavy Rogue-like elements. Combine upgrades, items and talents in new ways each run, to defeat all the different enemies you'll be facing throughout the forests, caves and beyond...

Become a Swordmancer, warriors capable of using an arsenal of living weapons to defeat their enemies. Level up, get upgrades and evolve your weapons into stronger versions in this roguelike survivor game!

You play as a rogue mage who tapped into dark arts to try and gain more power but as soon as you opened a dusty old book, Fafnir was summoned and not pleased, which caused him to place a curse on you and sent you to a eternal dungeon. Survive by beating the dungeon and breaking the curse.

From Digital Sun, creators of Moonlighter, The Mageseeker is an action RPG in the League of Legends universe. Play as Sylas, a mage now freed from years in captivity. Wield the chains that once bound you and liberate Demacia from the Mageseekers' tyranny.

A Fantasy Rogue-Like game with Paper thin graphics. Cut through waves of enemies and collect their souls to increase your power! Encounter a variety of enemies and events as you make your way through the DARK.

Slimenator is a roguelite where you battle endless waves of slimes trying to overtake the world! Choose and customize up to six powerful skills, along with rare relics and accessories, as you craft the ultimate build to survive the slime apocalypse and outlast the ever-growing swarm!

Rift Survivors is a 2D survivor-like game where you grow stronger by arranging your inventory. Equip items to unlock hidden powers and create your own unique build. Cross the rifts and survive against endless waves of enemies!

Mow down thousands of night creatures and survive until dawn! Vampire Survivors is a gothic horror casual game with rogue-lite elements, where your choices can allow you to quickly snowball against the hundreds of monsters that get thrown at you. Be the bullet hell!

Battle your way through the different worlds in AnotherOne with randomized enemies, upgrades, items, relics and much more. Roguelike action that assures you no run will ever be the same.

An action-adventure roguelike with a bit of RPG tossed in. Adventure deep into the UnderMine and discover powerful relics, deadly enemies, hidden secrets, and a few friends to help along the way.

Pixel Traveler is a rogue lite action game where players can freely edit skills and trigger chains. Design your own skill set; Utilize limited resources, transform and synthesize each other to obtain the ideal skill combination, and debug to maximize the effect.

La Furia de las Trenzas is a survivor-like roguelite where you'll face relentless hordes of British soldiers trying to capture Buenos Aires. Recruit your platoon of soldiers with special abilities and defend the town square! 

Guide 'Skul' on his quest to single-handedly take on the Imperial Army and rescue his King from captivity, in an action-packed rogue-lite 2D platformer for the ages.

Hack and slash your way through thousands of enemies in this action-packed casual game with rougelike features. Level up and gain access to a variety of abilities that will either increase your chances of surviving or get you killed even quicker.

A fast paced short byte-sized roguelike game where you play as a warlock taking bounties.

Dungeon Souls is an action-adventure roguelike dungeon crawler which draws heavy inspiration from Nuclear Throne, Risk of Rain, and Overture. Explore vast procedurally generated dungeons, collect loot, and slay hordes of challenging enemies!

A magical, chaotic roguelike-survivor. Craft insane wands, evolve and fuse powerful spells, equip crazy gear, and wield the power of divine relics. Get ready to wipe out hordes of hungry frogs and face mighty bosses in unique, unpredictable runs.

Crimen Exceptum is a spell-crafting action roguelike where you scavenge for equipment and combine magical spells to overcome all that stand in your path

Risk of Rain is an action platformer with roguelike elements. With permanent death as a primary feature, players will have to play their best to get as far as possible. Fight on a mysterious planet with randomly spawning enemies and bosses, either alone or with 3 friends in online co-op.

Murim Survival is a survival roguelite where you battle relentless enemies within a time limit. Explore a world on the brink of collapse, master martial arts, collect powerful equipment, and unlock unique traits to become a true hero of the Murim. The fate of this world is in your hands.