Top similar games like Anomaly Defenders:

Defense Grid: The Awakening is a unique spin on tower defense gameplay that will appeal to players of all skill levels. A horde of enemies is invading, and it's up to the player to stop them by strategically building fortification towers around their base.

Armoured Onslaught is a fast paced Top-Down Shooter and Tower Defence hybrid. You will need to make use of both strategy and skill as you fight your way through near endless hordes of deadly foes.

The ultimate mash-up of Real-time Strategy and Tower Defense!

Build up your fortifications, place your cannons, and fire at the enemy forces! Improve your Battle Haven with powerful upgrades while playing through a story campaign comprised of dozens of scenarios with unique mission types and multiple boss fights! Take to the sky and win!

An epic, challenging tower defense game with an emphasis on strategy and replayability. Summon gems of immense magical potency and harness their unique abilities against a seemingly endless horde of monsters. The archdemon seeks to swallow the world, and you must journey to stand against her.

Creeper World 3 is what happens when cellular automata takes over a strategy simulation. Instead of discrete units that attack your base, a fluid-like substance spreads over the terraformable terrain. Your base, your weapons, your strategy... you must adapt them all.

Embark on an adventure with Loot Express Delivery Service, a 2D pixel art game. As the commander, your goal is to retrieve valuable items from a distant planet. Utilize your skills and strategy to complete missions and guide your company to prosperity.

Command a team of 5 elite soldiers against an alien horde of 100,000. Surrounded on all sides, you must outmaneuver and outsmart the enemy.

Taur is an action-strategy sci-fi game. Control the Prime Cannon and unlock all of its powerful weapons and abilities. Build turrets, droids, aircraft and more as you fight to protect the homeworld of the Tauron droids against a relentless invasion. Will your Taur stand against the Imperion warmachine?

Scrap Bastion is a strategy tower defense game where you manage your city, equipping it to survive the waves of mutant creatures, testing your planning and decision making capacities at every turn. Watch out, as time is crucial to win!

The first ever auto-battler game, from way back in 2009Who needs backstory? Who needs resource-gathering? Diplomacy is so last year. Gratuitous Space Battles cuts right to the chase of sci-fi strategy games, and deals with large, completely unjustified space battles between huge opposing space fleets.

Rise of the Cones is a tower defense game where a relentless army of cones is marching toward your base. They will not stop. Build towers, shape them with branching upgrades, and figure out how to hold the line.

Sci-fi tower defense meets ARPG-like hero combat. Build towers then fight alongside them with your hero as you battle through a campaign to uncover the fate of a colonization effort on a distant planet.

Lead an armored squad through the perils of this reversed tower defense action-strategy game!

A roguelite base-defense game where your traps decide where enemies walk — and where they fall. Block a chokepoint so the whole wave comes down one road, line it with traps, and draft a new one from three cards after every wave. They won't make it easy: they dig through walls and tear traps apart.

Fight, build and engineer your way through five stages to protect a living energy Core. Corebound mixes twin-stick combat with deckbuilding, tower defence and a production network — every card, tower and weapon changes what the other three can do.

Prepare for the onslaught! Chromatrix is a retro tower defense game where color and placement are everything. Upgrade and customize your turrets to counter shifting enemy-types and map configurations. Manage your resources and craft the perfect defense against any attack!

Thousands of rift creatures. One base. Aim every turret's line of fire, then take the main cannon into your own hands. Take down five bosses across 15 maps, grow stronger between runs, and climb the global leaderboard in Endless. Build and share your own maps on the Workshop.

One laser. Build a machine of mirrors, splitters and lenses that burns every step of the path. Light gets tired: every enemy it passes through drains it, so where you split and where you strike is the whole game. A tower defense where you engineer the damage. When it slips mid-wave, grab a mirror.

Build towers, unleash ultimates and command six heroes in sci-fi tower defense. Play all 100 Scenario stages free. Try one-minute highlights of Basic and GRID COMMAND before purchase, then take your aerial fleet into GRID COMMAND's survival battles.

Molten Armor is an action tower defense game with a non-linear story in sci-fi setting! Command defenses and stop hordes of enemies! Fight on land, sea and in the skies!Decisions taken in the heat of battle will change the course of the war.

Star Pulse: The War is an independent real-time strategy game that merges science fiction with fantasy. Players will command a sci-fi faction, harnessing the power of star pulse to gather resources, construct buildings, train troops, and nurture heroes in the fight against invading magical forces.

Super Sanctum TD is a retro-styled Tower Defense game that focuses on strategy, customization and replayability. Build advanced mazes and construct powerful towers to prevent alien hordes from reaching the Core!

Drone swarms close in from every side: survive 10 minutes until reinforcements arrive. Level up mid-fight, build and modify 11 towers, break shields with the right damage type and bring down giant bosses in this neon roguelite tower defense.

Chess Defense is a strategy tower defense game where chess pieces become your towers.

Protect the asteroid mine's reactor from swarms of supersized alien protozoa. This game's groundbreaking AI system uses machine learning to adapt to your strategy in real-time as you build and upgrade your defenses. Fight evolution itself.

Terminal squad: swarmites is a game with indirect control where you must erect a chain of buildings, which generate resources for construction or the combat units for destruction of an enemy.

Wave defense with an RTS command layer. Your drones fight on their own until you take the controls. Mine the wreckage, draft upgrades between waves, and hold the line against an onslaught of asteroids.

Robicon is a tactical tower defense game with roguelite elements. Place and merge your towers, experiment with different builds, and crush endless waves of robotic enemies. Adapt, upgrade, and survive.

Unique fusion of a top-down shooter and tower defense strategy. You are the invader! Use destructive weapons or lead your enemies into a maze of towers. Strategize in the build mode by carefully selecting various types of alien towers or throw yourself right into the heat of the battle.

Build your defense base to repel alien invaders. Atahion is a strategy and tactical defense game in which you have to extract resources, build defense towers and use bonuses to complete the mission.

A roguelike tower defense with a card-driven twist. Build your deck, carve out tunnels, and deploy defences directly into the path of the swarm. Rank up your chosen Guild and rescue your Dwarven crew to get off this frackin’ slime-infested moon!

Hold the line in a neon sci-fi siege. Deploy and upgrade 15 distinct towers, expose every enemy's weakness, and survive 50 escalating waves and relentless boss assaults. Every threat has a counter — find it before your base falls.

ZAP Master is a 2D, abstract art, base defense game where players click to zap incoming enemies. Enemies spawn in and travel down radial lanes, and if one reaches the end of the lane, it's game over!

What if MOBAs and RTS games had a baby? Rover Wars combines resource management, farming, building and strategy into an intense tug of war. Fight in an interplanetary campaign and challenge your friends in the configurable Battle Mode. Rover Wars might be your gateway ticket into the strategy genre.