Top similar games like Anomaly Defenders:

Taur is an action-strategy sci-fi game. Control the Prime Cannon and unlock all of its powerful weapons and abilities. Build turrets, droids, aircraft and more as you fight to protect the homeworld of the Tauron droids against a relentless invasion. Will your Taur stand against the Imperion warmachine?

The ultimate mash-up of Real-time Strategy and Tower Defense!

Creeper World 3 is what happens when cellular automata takes over a strategy simulation. Instead of discrete units that attack your base, a fluid-like substance spreads over the terraformable terrain. Your base, your weapons, your strategy... you must adapt them all.

"In 'Random Core Defense,' acquire and enhance cores using limited resources to withstand relentless enemy onslaughts. Defeat powerful bosses and test your strategy to survive until the very end!"

Build your defense base to repel alien invaders. Atahion is a strategy and tactical defense game in which you have to extract resources, build defense towers and use bonuses to complete the mission.

Unique fusion of a top-down shooter and tower defense strategy. You are the invader! Use destructive weapons or lead your enemies into a maze of towers. Strategize in the build mode by carefully selecting various types of alien towers or throw yourself right into the heat of the battle.

The Echoes of Mars is a voxel-style tower defence game. Defend your research base on Mars from ancient creatures by strategically placing towers and using advanced tech.

Project Myriad 2 is a tower defense strategy game. Build towers on a grid of hexagons floating in space. 35 levels with unique tiles and mechanics each providing a unique challenge. 3 difficulty levels including extreme mode which has never ending waves of enemies. Strive for your new high score!

Super Sanctum TD is a retro-styled Tower Defense game that focuses on strategy, customization and replayability. Build advanced mazes and construct powerful towers to prevent alien hordes from reaching the Core!

Scrap Bastion is a strategy tower defense game where you manage your city, equipping it to survive the waves of mutant creatures, testing your planning and decision making capacities at every turn. Watch out, as time is crucial to win!

A roguelike tower defense game with a dash of deckbuilding. Choose a reward, improve your build, survive the next wave, repeat. Highly replayable, difficult, and addictive. You'll want just one more wave, just one more run!

Build your towers according to the enmey you are facing in the wave. Upgrade your turrets to increase range, damage or rewards. Each enemy wave will be random and increases in speed and damage resistance. How far can you go!

Private Mining Company is a tower defense game with perma-death and extraction elements. Keep your soldiers while you complete contracts, as long as they aren't killed. Make money defending mining outposts on hostile alien planets. Balance mining upgrades and growing your army.

Stop the escape of the infected automata in this Local Co-op Tower Defense First Person Shooter game for VR. Choose between playing solo or collaborating with a friend to build defensive structures and fight the Automata to avoid their escape.

Build your perfect defenses with hexagons! Use hex tiles to explore cyberspace, upgrade your defense towers, and complete quests in this unique turn-based strategy game. With a campaign, a procedurally generated endless mode, and a powerful editor, HexaScape offers endless challenges.

World of Towers combines puzzles with tower defense. Design your base in order to collect all of the puzzle pieces and destroy your enemies. Create and share your own worlds on the Steam Workshop using the World of Towers World Builder

Defend your kingdom by fighting back against an approaching robot invasion. Place, upgrade, and relocate elementally-charged towers strategically to destroy incoming robots. Watch as elements collide and combine to create explosive reactions!

"League Tower Defense" is a strategy tower defense game that combines unique defense towers and various upgradeable components to unleash different attack effects. Come and build your perfect defense line.

You think Tower Defense games are all about building? You thought wrong. Sanctum is not your average Tower Defense title. When the havoc starts, you get to join the fray! As one of the world’s first First Person Shooter - Tower Defense games, Sanctum has taken the best of both worlds to deliver an epic, one-of-a-kind experience.

Defense Grid: The Awakening is a unique spin on tower defense gameplay that will appeal to players of all skill levels. A horde of enemies is invading, and it's up to the player to stop them by strategically building fortification towers around their base.

Jump in to intense turret defense action with Sol Survivor! Build turrets to defend your colony and the innocent colonists within. Smash enemies with volleys of actively-controlled orbital support. Play with friends in co-operative and competitive multiplayer matches or test your mettle against our new Survival mode!

Setting the bar as the definitive tower defense game, Defense Grid 2 introduces new worlds and threats to test your tower placement strategies. With a bold new look and the addition of new game modes, player-versus-player and multiplayer co-op, every play brings fun new opportunities and challenges.

A strategic tower-defense where you control powerfull drones. Unlock new tower and use specific technologies to defend your base on Thukothea!

Space Run is a «real-time spaceship construction strategy game». Space Run takes the well-known Tower Defense-style gameplay and twists it, challenging you to manage and protect a spaceship and its cargo against the hazards of deep space!

Stellarcraft is a thrilling sci-fi tower defense game that delves deep into the vastness of the universe and offers players the opportunity to explore planets, collect resources and defend themselves against numerous threats.

Sanctum 2 is the sequel to the world’s first Tower Defense/FPS hybrid game. Pick from four unique character classes and embark on a mission to protect the oxygen-producing Cores from hordes of deadly aliens who are threatened by their existence.

Sentry System is a tower defense roguelike where you collect, modify and upgrade your sentries while progressing through a network of challenging encounters.

Galactic Garrison is a sci-fi, turn-based tower defense game where you defend your base from relentless alien waves on Mars. Deploy soldiers, build barricades, and upgrade defenses to withstand attacks. Earn powerful reward cards to gain strategic advantages and outmaneuver your enemies.

A tower defense adventure with endless strategy. Experience procedurally generated maps, unique foes, and a comprehensive tower upgrades system, as you progress through the waves. See how long you can hold down the homebase in this dynamic and replayable game!

Lunarpunk is the first Tower Attack ever made. A brand-new experience based on moving forward with your turrets to destroy the cosmic menace. Crush your enemies, develop new turrets, enhance those you have and try to overcome the crisis that desolates your world. Are you ready to push forward?

The Rift is a tower defense game with elements of RPG gameplay that will appeal to players of all skill levels. Enemies from an alternate universe are attacking and it's up to the player to stop them by strategically building defensive towers.

Defend the solar system from fearsome aliens by sending satellites into orbit in revolutionary tower defense action!

Build up your defenses and ward off any threats to your expedition in this rogue-like tower defense game. Manage your resources well and make sure no to overstay your welcome on this planet, or be prepared to face a never-ending onslaught of crustaceans...

Gear up and get going! Defend your outposts from waves of alien enemies with your mech. Build and upgrade your base, protecting the extraction of the mysterious planetary system’s rich resources!