Top similar games like Diffusion:

Build towers and learn abilities to defend against swarms of hundreds of on-screen hostile alien creatures. Choose between sets of randomized upgrades that both upgrade you and the alien swarm. From enormous explosions to far-reaching flamethrowers, no two games are the same.

Defend your Nexus by placing mirrors and buildings on the path of your projectiles. Deflect, empower, manage and solve each map using your creative and strategic mind.

A Byte War is a real time strategy game where you lead a race of block-based machines against a machine threat from another dimension. Construct buildings from blocks arranged in various patterns and leverage your machines to convert the world around you.

A rogue-like sci-fi Tower Defense strategy game with infinite replayability!

Build, Upgrade, and then Move your Towers in this unique twist on the Tower Defence genre. With Rogue-Lite mechanics every run offers new strategies, and every death unlocks new upgrades. Grow. Evolve. Destroy the Robots!

A Roguelike Tower Defense in space with missions to conquer. Can you hold against the spreading alien bosses? Build and upgrade towers against the corruption. Choose your technologies and warpspeed your way to victory.

Creeper World 3 is what happens when cellular automata takes over a strategy simulation. Instead of discrete units that attack your base, a fluid-like substance spreads over the terraformable terrain. Your base, your weapons, your strategy... you must adapt them all.

We've traveled to the past to conquer these fertile lands. Now, you must defend them from the blood cult intent on taking it for themselves. Be careful though: from where their blood is spilled, ancient magicks empower whomever is still alive.

Build your defense base to repel alien invaders. Atahion is a strategy and tactical defense game in which you have to extract resources, build defense towers and use bonuses to complete the mission.

A pixelated 2.5D RTS meets tower defense as you battle mutated ants in a short campaign. Build walls, place turrets, and hold the line to reclaim Earth's surface in this tactical fight for survival where placement of everything matters.

Build by day. Survive by night. A focused medieval tower defense where every decision is permanent.

Embark on an adventure with Loot Express Delivery Service, a 2D pixel art game. As the commander, your goal is to retrieve valuable items from a distant planet. Utilize your skills and strategy to complete missions and guide your company to prosperity.

The goblin tribes of the realm have united against you and the power of the Eye of the Void. Build towers, fortify walls, construct gold mines to gather resources, and cast powerful spells to fend off waves of determined goblins and their allies who seek to destroy you.

Build whimsical defenses, wield powerful relics, and command magical snow guardians to survive the infernal chaos. Can you hold the line through endless nights and defeat the Frost fallen King?

On an alien world, you must defend yourself in this unique base-building tower-defense game. Build a base by placing blocks, turrets and traps in order to survive the hoards of aliens.

Space Base is an action-packed tower defence game, where you aim to protect your planets from the incoming forces of enemy ships and aliens by any means necessary. Build up your defences as stronger and stronger waves of enemies arrive to reach the highest score possible.

Planet Gemini is a factory building and tower defense game. On two planets that crash-landed during a dimension trip, survive against incoming enemies and research on a portal to escape.

An Urban Survival RPG! Crafting, Exploring and Defending in a desolate metropolis haunted by the mysterious dreamers. Lead a team of 4 survivors through this urban desert of skyscrapers and high-rises, where the streets are crowded with the mutated victims of a strange disease.

Build & defend a small remote mining base on Taichin XI from the alien hordes. Deploy defenses, upgrade your turrets and get ready for the nightfall. The Unearthened is a classic Idle Tower Defense game where you build towers and prepare for the invasion.

Super Sanctum TD is a retro-styled Tower Defense game that focuses on strategy, customization and replayability. Build advanced mazes and construct powerful towers to prevent alien hordes from reaching the Core!

A maze-building tower defense where tower placement is everything. Force enemies the long way around, build choke points, push through lava, and adapt as levels change beneath you. No spells, no card modifiers. Just planning, placement, and a cat stuck in a jar.

Dawnhold is a top-down action base-defense game where you gather resources, build up your defenses, and survive relentless enemy waves. Strike back by assaulting enemy strongholds and defeating powerful bosses in a fight to protect the Sunstone.

You control a small colony in the underground of an unknown planet. Mine resources, build a base, explore the world and technology. Supply your colonists with oxygen, food and energy so that they can carry out their tasks.

A single-player survival RTS game about exploring the vast cosmos, the many planets inhabiting it and their countless secrets. You'll need to explore, gather resources and research new technologies in order to survive, thrive, and eventually build a colony on a bizarre, foreign world.

TAVU is a PvE RTS game with a tactical combat system. Build your bases and defend them against waves of enemy attacks. Upgrade your units and destroy enemy bases to gain new territories and resources.

Build your own towers from modular units, adapt mid battle, and master custom defenses in this Build-a-Tower Defense.

Turn-based space battle tactical/strategic game

A strategic tower-defense where you control powerfull drones. Unlock new tower and use specific technologies to defend your base on Thukothea!

Gutfarm is a top-down 2D pixel art game that blends farming, tower defense, and survival elements. On this alien island, you will expand and grow your farm by planting crops, unlocking genetically mutated varieties, defending against waves of monster attacks, collecting relics, and more!

Build, gamble, and most of all survive in this roguelike tower defense where everything is a tile. Use the slot shop to draft towers and physical upgrade tiles to buff your grid. With hundreds of unique synergies, will you hit the jackpot or let the enemies break your base? Play the odds today!

Bestion is a game that combines Roguelike tower defense elements with automated factory construction. Players are required to construct their own factory on a planet and protect the kernel from monster attacks.

Firewall, vaccine, cleaner... Place various blocks to protect your CPU! Vaccine A is a sandbox defense game, filled with parody of various programs.

Atlanta TD is a roguelite tower defense game where the armies of the underworld descend onto the Four Spectacular Realms in waves as it falls unto the remaining Gods to protect the city of Atlanta!