Top similar games like Diffusion:

Build towers and learn abilities to defend against swarms of hundreds of on-screen hostile alien creatures. Choose between sets of randomized upgrades that both upgrade you and the alien swarm. From enormous explosions to far-reaching flamethrowers, no two games are the same.

Defend your Nexus by placing mirrors and buildings on the path of your projectiles. Deflect, empower, manage and solve each map using your creative and strategic mind.

A Byte War is a real time strategy game where you lead a race of block-based machines against a machine threat from another dimension. Construct buildings from blocks arranged in various patterns and leverage your machines to convert the world around you.

A rogue-like sci-fi Tower Defense strategy game with infinite replayability!

Hexfall is a planet-scale tower defense game where over 100,000 enemies attack at once. Mine the crust, wire the power and arm a hex world against an armada that fills the sky long before it comes down.

Build, Upgrade, and then Move your Towers in this unique twist on the Tower Defence genre. With Rogue-Lite mechanics every run offers new strategies, and every death unlocks new upgrades. Grow. Evolve. Destroy the Robots!

A Roguelike Tower Defense in space with missions to conquer. Can you hold against the spreading alien bosses? Build and upgrade towers against the corruption. Choose your technologies and warpspeed your way to victory.

Creeper World 3 is what happens when cellular automata takes over a strategy simulation. Instead of discrete units that attack your base, a fluid-like substance spreads over the terraformable terrain. Your base, your weapons, your strategy... you must adapt them all.

We've traveled to the past to conquer these fertile lands. Now, you must defend them from the blood cult intent on taking it for themselves. Be careful though: from where their blood is spilled, ancient magicks empower whomever is still alive.

Build your defense base to repel alien invaders. Atahion is a strategy and tactical defense game in which you have to extract resources, build defense towers and use bonuses to complete the mission.

Von Neumann Project is about a self replicating probe as it charts the galaxies, peacefully of course. Mine, build, expand, and explore in this sci-fi RTS. Remember to have as little impact on your surroundings as possible and protect yourself at all costs.

A pixelated 2.5D RTS meets tower defense as you battle mutated ants in a short campaign. Build walls, place turrets, and hold the line to reclaim Earth's surface in this tactical fight for survival where placement of everything matters.

Embark on an adventure with Loot Express Delivery Service, a 2D pixel art game. As the commander, your goal is to retrieve valuable items from a distant planet. Utilize your skills and strategy to complete missions and guide your company to prosperity.

Build by day. Survive by night. A focused medieval tower defense where every decision is permanent.

Survive endless waves of dark entities, use your clicks as a resource, and grow stronger with every run. Find and upgrade powerful modules and unlock new technologies in this incremental clicker defense game. Also - Everything is square.

The goblin tribes of the realm have united against you and the power of the Eye of the Void. Build towers, fortify walls, construct gold mines to gather resources, and cast powerful spells to fend off waves of determined goblins and their allies who seek to destroy you.

Build whimsical defenses, wield powerful relics, and command magical snow guardians to survive the infernal chaos. Can you hold the line through endless nights and defeat the Frost fallen King?

Freely place a 15-chassis defense network, break visible enemy layers, and time Flux Gates, Protocol choices, commander abilities, and Overdrive across a 20-mission neon tower defense campaign.

On an alien world, you must defend yourself in this unique base-building tower-defense game. Build a base by placing blocks, turrets and traps in order to survive the hoards of aliens.

Space Base is an action-packed tower defence game, where you aim to protect your planets from the incoming forces of enemy ships and aliens by any means necessary. Build up your defences as stronger and stronger waves of enemies arrive to reach the highest score possible.

An Urban Survival RPG! Crafting, Exploring and Defending in a desolate metropolis haunted by the mysterious dreamers. Lead a team of 4 survivors through this urban desert of skyscrapers and high-rises, where the streets are crowded with the mutated victims of a strange disease.

Strategize your base to build and defend off waves of enemies in an on going battle. Plan, Attack, Defend and Grow! In the stratigic tower defense shooter.

Build & defend a small remote mining base on Taichin XI from the alien hordes. Deploy defenses, upgrade your turrets and get ready for the nightfall. The Unearthened is a classic Idle Tower Defense game where you build towers and prepare for the invasion.

Super Sanctum TD is a retro-styled Tower Defense game that focuses on strategy, customization and replayability. Build advanced mazes and construct powerful towers to prevent alien hordes from reaching the Core!

Hold the line in a neon sci-fi siege. Deploy and upgrade 15 distinct towers, expose every enemy's weakness, and survive 50 escalating waves and relentless boss assaults. Every threat has a counter — find it before your base falls.

A single-player survival RTS game about exploring the vast cosmos, the many planets inhabiting it and their countless secrets. You'll need to explore, gather resources and research new technologies in order to survive, thrive, and eventually build a colony on a bizarre, foreign world.

Dawnhold is a top-down action base-defense game where you gather resources, build up your defenses, and survive relentless enemy waves. Strike back by assaulting enemy strongholds and defeating powerful bosses in a fight to protect the Sunstone.

A hand-drawn survival tower defense on a hostile alien world. No fixed lanes — towers and ice walls reshape the swarm in real time. Command distinct frontline heroes, trigger ecological chain reactions, and defend the Purification Core across expanding battlefields.

Touhou Mushroom Defense blends resource gathering, base building, and tower defense into one survival adventure. Collect mushrooms, craft towers, create synergies, and survive for 30 days—or longer!

You control a small colony in the underground of an unknown planet. Mine resources, build a base, explore the world and technology. Supply your colonists with oxygen, food and energy so that they can carry out their tasks.

Build your own towers from modular units, adapt mid battle, and master custom defenses in this Build-a-Tower Defense.

Turn-based space battle tactical/strategic game

TAVU is a PvE RTS game with a tactical combat system. Build your bases and defend them against waves of enemy attacks. Upgrade your units and destroy enemy bases to gain new territories and resources.