Top similar games like Doom Keeper:

Defend against the alien invasion and take down the mother ship! Utilise branching upgrade trees, unlock new ships, and equip permanent upgrades to create your own unique build and defeat the growing hordes of invaders in this sci-fi action roguelike!

Spaceship Survivors is an anime-style arena survivor roguelike where you play in space to fight against loads of alien spaceships. Create unique builds to survive and kill the final boss, or go for an endless run. You can unlock 33 playable spaceships.

Microscopic SurvivalEmbark on a microscopic survival journey where you eat or be eaten.Simple controls meet strategic evolution in this unique roguelike RPG._Hunt the weak, flee the strong, and evolve your way to become the apex predator of this endless micro universe.

Dodge, dash, and destroy bugs with your squad in a fast-paced fight against a relentless insect invasion. Choose from a roster of elite exterminators, each armed with powerful weapons and elemental powers. Evolve your squad mid-run and unlock lasting upgrades to stand against the ever-growing swarm.

Survive endless waves of alien creatures and crush the heart of the infestation! Cyberage is a dark casual rogue-lite where you follow Phy’s journey to defeat an alien parasite. Level up, upgrade, and battle through hordes of relentless enemies!

Striving for Light: Survival brings the exploration of infinite expanding skill trees to the arena survival roguelite genre. Unlock new characters, weapons, skills and maps, slay hordes of monsters and take on massive boss fights.

Steel Defence is a tactical twin-stick roguelike where defeating a boss changes the arena's geometry. Build a loadout from 4 weapon classes, upgrade your mech with microchips, and adapt to survive when the solid ground suddenly becomes an abyss.

Shadow of the Depth is a top-down action Roguelite game. Delve into a dungeon world of light and shadow to eradicate the monsters that ravage your home. Be prepared to step into the abyss before you!

Shoot & Sow is a top-down arena shooter roguelite, where players control unique characters and fight vegetables and fruits. Players can plant seeds to grow special items, as well as buy a variety of weapons and items. Complete the talent tree to gain more power. Can you survive on your own farm?

lone.AI is a space RPG roguelite. With challenging, relentless gameplay, each run has the potential to boost your ship's power, speed, and more. As a lone AI, fight your way through the solar system and uncover the secret behind the ZOSMA, an alien race that holds power over the system.

Netspectre is a cyberpunk hacker roguelike: infiltrate networks, optimise your machine, conspire with your contacts, then change the world forever by making the ultimate run –

Swarmhunters is a top-down arena action shooter. The war between human and bugs has become worse - Project Swarmhunters emerged at this situation. You play as the best space soldiers in the galaxy and your mission is to strike the hive and hunt down the Emperor, supreme commander of bugs.

This is a rogue-like top-down shooter where you control a spaceship that is sent out to explore the caves on the Moon. Once you enter the caves, you find out that there are enemies. It is up to you to survive against them while also trying to find the path down to the next level of the caves.

Crabby Never Cry, Rock and Roll Never Die! Crab Rhapsody is a unique crab roguelite shooter where you can build upgrades and band in real-time to fight against CrabGPT — an AI trying to monopolize the Abysea’s music.🤘🎶🦀

Micron Survivor is a survival game with rogue-lite elements where you play as alien microorganisms under the microscope. Evolve, unlock research objectives, find symbiotic weapons, upgrade your builds, and fight hordes of terrestrial organisms to rule the microcosm.

Use your whip to protect the egg! Whip the enemies to defeat them. If there are too many, you can even whip the egg to spawn soldiers. But be careful, because there's a boss in the egg, and every damage shortens the hatching time. When it hatches, you'll need to defeat the boss

A top-down rogue-like shooter. Customize your weapons with looted upgrades to stay alive as long as possible.

Survive the relentless offensive of the alien horde in Let Them Come: Onslaught, a sci-fi survival roguelite. The pursuit of the perfect build and an ever-expanding arsenal of abilities are the keys to your success.

Fight for survival in B.L.A.C.K - 1, a 3D FPS roguelike set in a dystopian future. Battle through procedurally generated spaceships using all your skills and resources, in Zero-G environments. Can you survive long enough to finally escape from enemy territory?

Digital Frida is a roguelike arena game in stylized 2D graphics.Welcome to the online virtual reality server "Digital Frida", where you can become whoever you want, do whatever you want and be wherever you want!

Don't Go Unarmed is a randomly generated action RPG shooter with heavy Rogue-like elements. Combine upgrades, items and talents in new ways each run, to defeat all the different enemies you'll be facing throughout the forests, caves and beyond...

You are military volunteer. what? you did not volunteer? It's too late! You are already in the middle of the battlefield. kill the alien for the humanity! Marine Survivors is simple action rogue lite game. kill aliens, earn exp gem, upgrade your weapon. unlock various collection.

Fight hordes of Covenant & Flood in this new game mixing Roguelite & Bullet Heaven for hours of mindless fun!

A creature-collecting roguelike where every monster is sculpted in real clay and brought to life! Collect and battle a random assortment of hand-sculpted monsters in order to become the #1 Sculpling Champion!

You are a KING - a being with the power to travel through dimensions to save corrupted realms. Fight hordes of enemies, find the HEARTS of the KINGS, unlock new characters and discover the secrets of each dimension.

Vector Prospector is an arcade action roguelite with simple, precise movement that rewards skill and quick thinking. Unlock powerups and ships to explore the caverns beneath an alien world, collect the five green gems, and escape alive.

Our Tribe Above All is an epic online co-op survival game that masterfully blends survivor combat with online multiplayer. Make crucial strategic decisions and choose to grow in power collectively or isolate yourself for individual gains while fending off relentless hordes.

Swing, smash, and combo your way through the dead. DIVINE SHOCK is an infinitely scaling first-person rogue-lite, where you are a Paladin, standing between the dead and the mortal realm.

An endless roguelite with flappy controls and randomised power-up mechanics.

Will you dare to challenge the Cyberfield champions? Gather a unique combination of skills and enhancers in this roguelike game to rise to the pedestal of the best warriors of the steel arena.

Take command of a spaceship, try to get home. A science fiction adventure game.Weapons, crew, morally ambiguous actions and cats in spacesuits.

A free-to-play sci-fi action roguelike game set in an alien world where the sun never shines. Explore the world as a ‘Planet Adventurer’. Fight hostile creatures, gather ore, and interact with the local community in your downtime. Upgrade your gear with resources earned during your expeditions.