Top similar games like Plasma Dome:

An open-ended factory management game with RTS and tower defense elements.

Heart of Machine blends top-down tower defense with light roguelite elements. Face an evolving mechanical swarm thousands strong, tailor defenses, upgrade towers with chips, and use real-time support weapons to turn the tide. Build an unbreakable line and save the core from destruction.

Expand your moving village while monsters try to tear it down in this strategic horde survival. Combine blessings, level-ups, orbs and buildings to create the ultimate survival machine!

On a forgotten world, confront a malevolent machine intelligence. Extract minerals, build factories, power up the railguns, and arm the missile batteries. Defend the Fortress Omega against the alloyed nightmare.

In Vermin Control, you will enter a thrilling sci-fi tower defense world filled with strategic combat and high tension. Operate a versatile unit capable of both melee combat and construction, deploy and manage 9 unique devices, and protect key facilities from relentless vermin assaults.

Creeper World 3 is what happens when cellular automata takes over a strategy simulation. Instead of discrete units that attack your base, a fluid-like substance spreads over the terraformable terrain. Your base, your weapons, your strategy... you must adapt them all.

Mechs V Kaijus is an addictive hardcore tower defense gameplay. In Mechs V Kaijus you take on the role of Commander of a powerful Mechs squadron. Improve your Mech, strategically place towers and factories on the battlefield. Deploy support units on the battlefield, and save our civilization.

Survive on a hostile planet by automating a factory, fighting alien waves, and buying random upgrades. Hold out until the cleansing bomb drops! Roguelike strategy with drones & survival.

Build and design the terrain while defending your stronghold against alien invasion in this unique Roguelike tower defense. Choose from 30 heroes, survive enemy waves, and upgrade a variety of destructive towers to hold the line!

Infinitory mixes city-building, automation, and tower defense in a in a rogue-lite top-down game. Expand your base vertically in limited space, a strategic planning challenge. Automate resources to produce ammunition and upgrades, crucial for stopping waves of enemies on procedurally generated maps.

A Byte War is a real time strategy game where you lead a race of block-based machines against a machine threat from another dimension. Construct buildings from blocks arranged in various patterns and leverage your machines to convert the world around you.

A rogue-like sci-fi Tower Defense strategy game with infinite replayability!

Orestorm Factory is a bullet hell, automation rogue-like where everything is a hazard. Build a factory of drills and processors to loot a cave, while dodging your way past enemies and your own deadly machinery along the way.

Survive endless waves of dark entities, use your clicks as a resource, and grow stronger with every run. Find and upgrade powerful modules and unlock new technologies in this incremental clicker defense game. Also - Everything is square.

Dig minerals, manufacture ammunition, and build defense towers to fend off swarms of insects. A tower defense game with light production line elements.

Feed your scrap hungry factory in this real time strategy roguelike. Command your army of robots through the wasteland to fight for scraps and upgrades. Are you ready to defend your base as the cloud king invades night after night? Or will you turn the tide and invade the cloud king?

Build deadly mazes and outsmart a rogue AI in this strategic tower defense game. Adapt your defenses, use aiming parameters to your advantage, and activate powerful perks to survive increasingly complex waves of incoming robots.

Cube Chaos is a complex strategy roguelike about placing units to create giant armies, factories, combos, or self replicating murder crabs, overwhelming and outsmarting your opponents. Build and adapt new strategies each run using a ludicrous variety of units, perks and more.

Defend your AI capital against endless alien invasions in this space shmup-inspired tower defense with roguelite randomness. Dissect bodies and ships to unlock weirdly powerful tech. Upgrade your base with turrets, turning your screen into a symphony of perfect destruction!

Hunger Gods is a roguelike tower defense game, where your ultimate goal is to spread and defend the influence of the blood-thirsty God of your choice. Repel waves of vindictive humans to definitely re-instate your Master, and mold the World to its will.

Acid Planet is a caustic blend of horde-survival, tower-defense and strategy. Build, fight and evolve to survive against rampaging swarms of monsters and fearsome Kaiju.

Von Neumann Project is about a self replicating probe as it charts the galaxies, peacefully of course. Mine, build, expand, and explore in this sci-fi RTS. Remember to have as little impact on your surroundings as possible and protect yourself at all costs.

Negative Energy is a tower defense game with basic RTS mechanics, where your goal is to defend the construction of a Dyson sphere, while fighting against waves of hundreds of enemies ships.

Build, automate, and defend humanity's last factory on a dying industrial planet. Chain production lines, survive AUTON raids and dust storms, research lost technology, and uncover what silenced every factory before yours.

Empires of a Tiny Universe is a relaxed single-player RTS where you build and expand your empire across space. Manage planetary infrastructure, develop new technologies for your fleet, and conquer the galaxy - all from a clear, minimalist perspective.

Fort Laboratory is a 2D tower defense game with elements of roguelike gameplay. Players must build bases, weapons, and factories to defend against hordes of enemies. Collect a variety of items and structures to create a unique defense system and protect the core of the base until the attack is over.

A planetary tower defense where enemies attack across land, air, and space. Build layered defenses, manage resources, and survive an escalating alien invasion.

Tower Defense with resource- and base management! Waves of enemy robots with special abilities, shield and armor! Mining, refining and production for building and repairing! Environmental hazards and the best: the Orbital strike!

Xenogarden is a dark sci-fi strategy game where you spread an alien swarm, build synapse nodes, defend your core, and overwhelm human defenders before they destroy your living network and cut the invasion apart.

"Slime Warfare" is a rogue tower defense game with a variety of gameplay and placement.Slimes are weak monsters and always bullied by humans. Players will play the role of the Slime Queen to build structures to defend against adventurers' attacks and strengthen themselves.

Milky Way is a unique mix of Tower Defense, RTS, Auto-Battler and Survivors. Build your base, choose random upgrades and use powerful skills to survive against hordes of enemies.

Delve for materials, machines and curiosities in this game inspired by Dungeon Keeper and Pikmin.

Strategize your base to build and defend off waves of enemies in an on going battle. Plan, Attack, Defend and Grow! In the stratigic tower defense shooter.

Astra Sentinel is a wave-based survival RTS where endless alien hordes relentlessly assault your planets. Build defenses, colonize planets and manage resources under constant pressure. Will you be able to recover the control of the galaxy?